Loading...
  • enzyme
  • While these oxidations are often of benefit to the body, certain carcinogens and toxins are bioactivated by CYP2E1, implicating the enzyme in the onset of hepatotoxicity caused by certain classes of drugs (see disease relevance section below). (wikipedia.org)
  • membrane
  • This work was therefore designed to assess the phytochemical constitution of P. hysterophorus flower and root extracts and to evaluate their reducing power, radical scavenging activity as well as protective efficacy against membrane lipid damage. (biomedcentral.com)
  • Maximum protection against membrane lipid peroxidative damage among flower and root extracts was provided by ethanol (55.26%) and ethyl acetate (48.95%) fractions, respectively. (biomedcentral.com)
  • Removal of excess reactive species, suppression of their generation or protection against per-oxidation by repair of membrane damage may be an efficient way of preventing diseases. (biomedcentral.com)
  • Vitamin E has also found use as a commercial antioxidant and biocompatible modifier of biomaterials and medical devices, for example in ultra high molecular weight polyethylene (UHMWPE) used in hip and knee implants by resisting oxidation and in hollow-fiber membrane cartridges used in extracorporeal hemodialysis therapy. (wikipedia.org)
  • vitro
  • The amplification of low-density lipoprotein (LDL) peroxidation in vitro by copper and myoglobin are well-studied biochemical approaches for investigating the oxidative modification of LDL and its role in the pathogenesis of atherosclerosis. (biomedsearch.com)
  • presence
  • The presence of a large lipid core, necrotic tissue, macrophages, and a thin fibrous cap predisposes to plaque rupture. (ahajournals.org)
  • 4 Conversely, a relative absence of lipid and macrophages and the presence of a thick fibrous cap renders a plaque stable. (ahajournals.org)