Reactive Oxygen SpeciesOxidantsOxygenOxidative StressHydrogen PeroxideAntioxidantsNADPH OxidaseOxidation-ReductionFree Radical ScavengersMitochondriaSuperoxide DismutaseCatalaseOxygen ConsumptionAcetylcysteineSuperoxidesGlutathioneApoptosisCells, CulturedMembrane Potential, MitochondrialLipid PeroxidationSignal TransductionXanthine OxidaseReactive Nitrogen SpeciesOnium CompoundsSinglet OxygenCyclic N-OxidesFree RadicalsCell SurvivalCell DeathHydroxyl RadicalNitric OxideEnzyme ActivationGlutathione PeroxidaseEnzyme InhibitorsDNA DamageCell Line, TumorDose-Response Relationship, DrugAscorbic AcidRats, Sprague-DawleyCell LineRotenoneXanthineVitamin K 3tert-ButylhydroperoxideMice, Inbred C57BLRespiratory BurstBlotting, WesternTime FactorsLuminescent MeasurementsHypochlorous AcidAcetophenonesNeutrophilsCytochromes c1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium SaltMitochondrial ProteinsMetalloporphyrinsMitochondria, HeartMalondialdehydePeroxiredoxinsAnoxiaEndothelium, VascularModels, BiologicalMice, KnockoutCaspase 3Oxygen Inhalation TherapyGlutathione DisulfideParaquatNF-E2-Related Factor 2DeoxyguanosineProtein CarbonylationElectron Transport Complex ICell HypoxiaCaspasesSpin LabelsElectron TransportCell RespirationRats, WistarRNA, MessengerNF-kappa BPhosphorylationPeroxynitrous AcidThioredoxinsNADH, NADPH OxidoreductasesDNA FragmentationUp-RegulationCytoprotectionDisease Models, AnimalPeroxidesThiobarbituric Acid Reactive SubstancesPeroxidaseSulfhydryl Compoundsp38 Mitogen-Activated Protein KinasesHeme Oxygenase-1Gene Expression RegulationCalciumDeferoxamineTioproninrac1 GTP-Binding ProteinPeroxidasesEndothelial Cells