• mixed gonadal dy
  • pure or mixed gonadal dysgenesis and may exhibit varied karyotypes including 46XY or 45X, 46XY (1) Approximately 12% of individuals with Turner syndrome have Y chromosome material, but the incidence of gonadoblastoma in these individuals is about 7-10% (2). (upmc.edu)
  • chemotherapy
  • The role of chemotherapy or radiation therapy in the treatment of granulosa cell tumors remains uncertain because of the lack of prospective randomized trials supporting their roles as adjuvant agents. (appliedradiology.com)
  • The survival rate for germinomatous tumors is higher in part because these tumors are very sensitive to radiation, and they also respond well to chemotherapy. (omicsgroup.org)
  • Fallopian
  • The side of the ovary closest to the fallopian tube is connected to it by infundibulopelvic ligament , and the other side points downwards attached to the uterus via the ovarian ligament . (wikipedia.org)
  • The ovarian pedicle is made up part of the fallopian tube , mesovarium , ovarian ligament, and ovarian blood vessels. (wikipedia.org)
  • arise
  • It is believed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge. (urotoday.com)
  • These tumors arise primarily in the retroperitoneum and are exceedingly rare. (urotoday.com)
  • These tumors can also arise rarely in apparently normal women with a history of pregnancy (3). (upmc.edu)
  • carcinoma
  • Teratocarcinoma refers to a germ cell tumor that is a mixture of teratoma with embryonal carcinoma , or with choriocarcinoma , or with both. (omicsgroup.org)
  • [ 6 ] This kind of mixed germ cell tumor may be known simply as a teratoma with elements of embryonal carcinoma or choriocarcinoma, or simply by ignoring the teratoma component and referring only to its malignant component: embryonal carcinoma and/or choriocarcinoma. (omicsgroup.org)
  • There are five main subtypes of ovarian carcinoma, of which high-grade serous carcinoma is the most common. (wikipedia.org)
  • Histologically
  • Portions of this tumor histologically demonstrated mature elements of skin, bone and mature neural tissue including choroid plexus, neuroglia and cerebellar tissue. (upmc.edu)
  • tend
  • They are often suspected of being malignant prior to operation, being solid ovarian tumours that tend to occur most commonly in post menopausal women. (wikipedia.org)
  • these tumors tend to have late recurrencies ( even after 30 years ) Using next generation DNA sequencing, it was discovered that 97% of granulosa cell tumours contain an identical mutation in the FOXL2 gene . (wikipedia.org)
  • These hereditary cases tend to be younger, often have a multinodular thyroid goiter and there may be a personal or family history of other rare tumors such as pleuropulmonary blastoma, Wilms tumor and cervical rhabdomyosarcoma. (wikipedia.org)
  • marker
  • Most dysgerminomas are associated with elevated serum lactic dehydrogenase (LDH), which is sometimes used as a tumor marker . (wow.com)
  • postmenopausal
  • It typically secretes estrogen, and as a result women with this tumour often present with postmenopausal bleeding. (wikipedia.org)
  • In a study of 125 patients with juvenile granulosa cell tumors, 78% presented within the first 2 decades of life.3Clinically, these patients typically presentwith signs of hyperestrogenism-precocious puberty in pre- pubertal patients, menstrual irregularities in women of reproductive age, and abnormal uterine bleeding in postmenopausal women. (appliedradiology.com)
  • cystic
  • Cut section revealed solid homogenous grayish white tumor with small cystic areas and areas of haemorrhages (Figure 1 ). (hindawi.com)
  • tissue
  • The remainder of the tissue was replaced by tumor composed of sharply circumscribed nodules composed of small, dark cells interspersed with larger, paler cells often centered around hyaline bodies. (upmc.edu)