Ovarian synthesis theca cells. Medical search. Frequent questions

At the time of puberty, women have approximately 200,000 to 300,000 follicles, each with the potential to release an egg cell (ovum) at ovulation for fertilization. (wikipedia.org)
Ovarian follicles are the basic units of female reproductive biology. (wikipedia.org)
The primary oocyte turns into a secondary oocyte in mature ovarian follicles. (wikipedia.org)
It also remains in question the extent to which BPA penetrates developing ovarian follicles. (desdaughter.com)
The problems mostly commonly occur when the ovarian pool of follicles is depleted to a critical level with age but are also found in low follicular reserve of other etiologies. (biomedcentral.com)
DHEA controls critical elements of the ovarian environment at the earliest stage of maturation of the follicles, some 70 days before ovulation. (theconversation.com)
Ovarian follicles in animals under heat stress are damaged but continue to grow. (roshddanehkhavaran.com)
Nicotine induced a reduction in the proliferative indexes of granulosa and theca cells in pre-antral and antral follicles ( P = 0.001). (biomedcentral.com)
Co-Treatment with ginseng also reduced the expression of apoptotic markers and increased the proliferative indexes in granulosa and theca cells in pre-antral and antral follicles and also in stroma cells, in comparison to the nicotine group ( P = 0.001). (biomedcentral.com)
Only a few follicles in the human ovary survive to complete the cytodifferentiation process, with 99.9% dying by a programmed cell death mechanism called apoptosis. (glowm.com)
Regulation of bovine tumor necrosis factor alpha induced protein 6 in ovarian follicles during the ovulatory process and promoter activation in granulosa cells. (appliedbioinfo.com)
In this review, we highlighted some of the main gene networks and regulatory mechanisms involved in the plasticity of sex-determining pathways that help to establish a functional ovary that can nurture the follicles to generate a good ovarian reserve, both in quantity and quality. (lidsen.com)
Additionally, reproductive hormones regulate RAS activity in the cellular physiological function of ovarian follicles during pre-ovulatory maturation and ovulation. (encyclopedia.pub)

An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. (wikipedia.org)
They also consist of granulosa cells and theca of follicle. (wikipedia.org)
Cumulus oophorus is a cluster of cells (called cumulus cells) that surround the oocyte both in the ovarian follicle and after ovulation. (wikipedia.org)
Any ovarian follicle that is larger than about three centimeters is termed an ovarian cyst. (wikipedia.org)
Presently, ovarian follicle volumes can be measured rapidly and automatically from three-dimensionally reconstructed ultrasound images. (wikipedia.org)
To more definitively address the potential risk of BPA on human ovarian steroidogenesis, additional experimental studies using biologically active BPA doses likely to reflect those within the ovarian follicle will be necessary, as will additional prospective investigations in human populations with the use of standardized assay methodology. (desdaughter.com)
Reduced quality and accelerated follicle loss with female reproductive aging - does decline in theca dehydroepiandrosterone (DHEA) underlie the problem? (biomedcentral.com)
In females with normal fertility, pre-antral ovarian theca cells respond to stimulation by inhibin B to provide androgen-based support for the developing follicle. (biomedcentral.com)
With depletion of follicle numbers, inhibin B is reduced with consequent reduction in theca DHEA. (biomedcentral.com)
Theca and granulosa cells in the follicle may also be damaged during heat stress. (roshddanehkhavaran.com)
In vivo study in treated rats by nicotine also resulted in the reduction of follicle numbers, and ovarian cholesterol and glycogen elevation [ 9 ]. (biomedcentral.com)
The remaining cells in the follicle wall ( i.e. granulosa, membrana and periantral, theca, the theca interna and externa) develop into the corpus luteum. (glowm.com)
From Blandau RJ: Growth of the ovarian follicle and ovulation. (glowm.com)
During the course of folliculogenesis, growth is achieved by cell proliferation and formation of follicular fluid, whereas development involves cytodifferentiation of all the cells and tissues in the follicle. (glowm.com)
Specialized hypothalamic neurons secrete pulses of gonadotropin-releasing hormone (GnRH) into the portal blood vessels, which acts on the gonadotrophs to cause a pulsatile release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which act on ovarian follicle cells to control folliculogenesis. (glowm.com)
The production of estrogen and at a lower magnitude testosterone by the theca of the growing follicle increases 2 to 3 weeks before the production of the first egg and contributes to the development of reproductive organs and the synthesis of egg constituents [ 1 - 6 ]. (biomedcentral.com)
The relatively narrow intercellular space of the primordial follicle allows ferritin and possibly other molecules of similar size to cross, whereas in the late stages of rapid follicular growth, the shape of granulosa cells must accommodate the increasing flow of egg yolk precursors that accumulate at the surface of the plasma membrane of the follicle [ 7 ]. (biomedcentral.com)
COS was given to mice through the best route of administration, and the changes in ovarian and immune function were detected using assays of organ index, follicle counting, serum estrogen (E 2 ) and anti-Mullerian hormone (AMH) levels, and the expression of IL-2 and TNF-α in the ovaries. (biomedcentral.com)
Its essence is ovarian follicle depletion, and the resulting low estrogen levels in the ovary induce the occurrence and development of many other diseases [ 1 ]. (biomedcentral.com)
Women under 40 years of age, who have hypomenorrhea or amenorrhea for at least 4 months, and whose follicle stimulating hormone (FSH) level are greater than 25 U/L, are defined as premature ovarian failure(POF )[ 2 , 3 ]. (biomedcentral.com)
This discovery invalidated the "fixation theory of primordial follicle pool" and suggested for the first time the hypothesis that germ stem cells also exist in the ovary. (biomedcentral.com)

In affected ovaries, oxygenation of follicular fluid is low, ultrastructural disturbances especially of mitochondria, occur in granulosa cells and oocytes, and considerable disturbances of meiosis occur. (biomedcentral.com)
In females, specialized cells in the ovaries called theca cells make testosterone. (tabadc.org)
When it comes to the ovaries, the pituitary hormone LH causes the uptake of cholesterol into and the production of pregnenolone within the ovarian theca cells that is then turned into testosterone. (drfionand.com)
In the ovaries, LH acts on theca and interstitial cells to produce progestins and androgens, and FSH acts on granulosa cells to stimulate aromatization of these precursor steroids to estrogen. (diseasesdic.com)

Progesterone is only produced by the theca cells after ovulation has occurred until the ovarian corpus luteum cells degenerate. (drfionand.com)
In the ovarian cycle, repeated patterns of specific cellular proliferation, differentiation, and transformation occur that accompany the formation and regression of the corpus luteum. (encyclopedia.pub)
Recently, we focused on the role of RAS protein in the ovarian corpus luteum. (encyclopedia.pub)
In the ovarian cycle, repeated patterns of specific cellular proliferation, differentiation, and transformation occur that accompany the process of follicular development and the formation and function of the corpus luteum [ 2 ] . (encyclopedia.pub)
However, the function of RAS in the ovarian corpus luteum is not clear. (encyclopedia.pub)

D-chiro Inositol reduces the effects of polycystic ovary syndrome (PCOS) activity in cells. (jerodtaylor.com)
This study showed ginseng protects folliculogenesis via alteration of hypothalamic- pituitary-gonadal (HPG) axis, induction of proliferation in ovarian somatic cells, reduction of lipid peroxidation, and downregulation of apoptotic markers in the mouse ovary, treated with nicotine. (biomedcentral.com)
The process of ovulation itself involves great change in the production of estradiol, testosterone and progesterone within the cells of the ovary in a cyclic pattern. (drfionand.com)
Polycystic Ovary Syndrome (PCOS) and Premature Ovarian Insufficiency (POI), were selected and briefly discussed in this review. (lidsen.com)
The most common human ovarian pathologies that cause infertility are Polycystic Ovary Syndrome (PCOS) and Premature Ovarian Insufficiency (POI), and both pathologies have been briefly discussed at the end of the review. (lidsen.com)
It was found that ovoid cells in the epithelial layer of the ovary simultaneously expressed the germ cell specific marker MVH and the proliferation of cell marker BrdU using double-immunofluorescence staining. (biomedcentral.com)
Niikura [ 5 ] and others observed germ cells expressing Stra8 (stimulated by retinoic acid gene 8) in the ovarian surface epithelium, indicating that there may be germ cells with meiotic function in the ovary. (biomedcentral.com)
Ovarian drilling is treatment that is given to patients with polycystic ovary syndrome in order to encourage spontaneous ovulation. (tipsforwoman.com)
Synthesis of estrogens starts in theca interna cells in the ovary, by the synthesis of androstenedione from cholesterol . (wikidoc.org)

Outside the basal lamina, the layers theca interna and theca externa are found. (wikipedia.org)

Testosterone is used as a marker of ovarian androgen secretion. (medscape.com)
This testosterone is passed over to the granulosa cells. (drfionand.com)
The influence of pituitary FSH on the granulosa cells causes testosterone to turn into estradiol. (drfionand.com)
LH activates theca cells to produce testosterone and the granulosa cells are usually secreted by FSH and there will be low estrogen. (tipsforwoman.com)
In the testes, LH stimulates Leydig cells to secrete testosterone, whereas FSH is necessary for tubular growth. (diseasesdic.com)
This compound crosses the basal membrane into the surrounding granulosa cells , where it is converted to estrone or estradiol, either immediately or through testosterone. (wikidoc.org)

Previously, we have demonstrated that simvastatin inhibited cellular proliferation and reduced androgen production by ovarian theca-interstitial cells. (uky.edu)
The objective of this study was to determine the gene expression profiles of the androgen/androgen receptor (AR) and anti-Müllerian hormone (AMH)/ Sry-related high-mobility group box 9 (SOX9) pathways in granulosa-luteal cells from patients undergoing standard in vitro fertilization (IVF) with or without recombinant luteinizing hormone (rLH) therapy. (biomedcentral.com)
The effects of androgen and rLH treatments on AR and AMH expression levels were also tested in vitro using HO23 cells. (biomedcentral.com)

The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line Cancer Cell International. (nottingham.ac.uk)
RAS protein plays a vital role in the modulation of cell survival, proliferation, and differentiation by molecular pathway signaling. (encyclopedia.pub)
RAS family proteins play a vital role in the modulation of cell survival, proliferation, and differentiation by signaling through a set of molecular pathways [ 10 ] . (encyclopedia.pub)
The ovarian microenvironment affects the proliferation and differentiation of OGSCs, and immune cells and related cytokines are important components of the microenvironment. (biomedcentral.com)
However, whether improving the ovarian microenvironment can regulate the proliferation of OGSCs and remodel ovarian function has not been reported. (biomedcentral.com)
With increasing time, the fluorescence intensity of cells gradually increased, and the cytokines IL-2 and TNF-α significantly promoted the proliferation of OGSCs. (biomedcentral.com)
It is worth noting that the proliferation and differentiation of stem cells cannot be separated from the surrounding microenvironment, and immune system related cells are an important part of the microenvironment of the OGSCs nest [ 14 ]. (biomedcentral.com)

DHEA supplementation may also be dangerous for some women, especially those with polycystic ovarian syndrome where there is often already excess DHEA. (theconversation.com)
Two major causes of infertility are polycystic ovarian syndrome (PCOS) and suboptimal sperm . (levelshealth.com)

Ovarian androgens are produced by thecal cells and exert their action in a paracrine fashion on granulosa cells. (biomedcentral.com)

The granulosa cells, in turn, are enclosed in a thin layer of extracellular matrix - the follicular basement membrane or basal lamina (fibro-vascular coat in picture). (wikipedia.org)
Ovarian function may be measured by gynecologic ultrasonography of follicular volume. (wikipedia.org)
This provides conditions for increased ceramide synthesis and follicular loss through ceramide-induced apoptosis is accelerated. (biomedcentral.com)
Levels of reproductive hormones in the pre-ovulatory follicular fluid and the expression levels of LHR (luteinizing hormone receptor), AR, SOX9, AMH, AR-associated protein 54(ARA54)and ARA70 were determined in granulosa-luteal cells by real-time reverse-transcription PCR. (biomedcentral.com)
Increases in the amount of PAPP-A mRNA in granulosa cells during follicular development occurs in some but not all species, indicating that other proteases or protease inhibitors may be involved in IGFBP degradation. (bioone.org)

Additional data suggest that BPA reduces endogenous estrogen synthesis, likely by antagonizing ovarian enzyme activities involved in sex-steroid hormone synthesis. (desdaughter.com)

Each of them contains a single oocyte (immature ovum or egg cell). (wikipedia.org)
The ovarian cycle is a highly orchestrated, and complex developmental process that depends on functional interactions and critical signaling pathways that communicate between the ovarian microenvironment elements, including the oocyte, granulosa cells, theca cells, and surrounding stromal components, including vascular and immune cells [ 3 ] . (encyclopedia.pub)

The synthesis and actions of these estrogens are complex. (medscape.com)

does decline in theca dehydroepiandrosterone (DHEA) underlie the problem? (biomedcentral.com)
Theca cells are the sole ovarian site of synthesis of DHEA, which is both a precursor of androstenedione and an essential ligand for peroxisome proliferator-activated receptor alpha (PPARα), the key promoter of genes affecting fatty acid metabolism and fat transport and genes critical to mitochondrial function. (biomedcentral.com)
This in turn reduces the synthesis of a hormone called DHEA dehydroepiandrosterone , which is produced both by the ovarian theca cells and the adrenal gland. (theconversation.com)
However, normal levels of DHEA are also required for the activation of another hormone called PPAR alpha which controls over 200 genes, especially those regulating mitochondria (the powerhouse of the cell) and fat metabolism. (theconversation.com)

Once gametogonia enter the gonadal ridge, however, they attempt to associate with these somatic cells. (wikipedia.org)
Mutations in these cells (i.e., "generative" cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not. (lookformedical.com)

Metabolism and ovarian function in PCOS women: A therapeutic approach with inositols. (jerodtaylor.com)
The effect of myo-inositol/di-chiro-inositol on markers of ovarian reserve in women with PCOS undergoing IVF/ICSI: A systematic review and meta-analysis. (jerodtaylor.com)
Key benefits include ovarian, menstrual, PCOS & fertility support. (jerodtaylor.com)

Symptoms secondary to changes in ovarian hormones can be difficult to distinguish from those due to general aging and/or other medical or endocrine disorders. (medscape.com)

The decrease in estradiol synthesis has made the appearance of estrus a problem, which is one of the effects of heat stress in the fertility process or low fertility in animals under heat stress. (roshddanehkhavaran.com)
In this review, we focused on the molecular mechanisms of ovarian sex determination and on understanding mutual cross-talks between central molecules in sex development which might impact fertility later in adult life. (lidsen.com)

Ovarian steroid hormone formation takes place in the ovarian granulosa and theca cells, which work in a collaborative way for the synthesis after stimulation by the gonadotropins LH and FSH. (susannepaulus.art)
Interestingly, stimulation of CALU-3 cells with forskolin, a cAMP agonist, slightly increased MUC1 surface expression and decreased MUC1 release. (healthdrugpdf.com)

G protein-coupled receptors , also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors , comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal. (absoluteastronomy.com)
Collectively, the effects of brefeldin A are consistent with a model in which MUC1 surface expression is dependent upon both protein synthesis and membrane release. (healthdrugpdf.com)
Furthermore ORP-150, a novel protein that is expressed by macrophages under ischemic conditions, is likely to be critical in enabling these cells to redirect their biosynthetic activities in hypoxia. (healthdrugpdf.com)
Further analyses and immunohistochemistry indicated that this increase in transcript and protein levels occurred in theca and granulosa cells. (appliedbioinfo.com)
Protein synthesis and lipogenesis are highly stimulated in the liver at sexual maturity in hens (15 to 20 fold) to support the incorporation of 0.75 kg proteins and 1.5 kg of triglycerides into the yolk over a year of commercial production. (biomedcentral.com)
Given that betaine has been suggested to boost greater levels of muscle protein synthesis and can decrease cortisol levels, it makes sense to put those doses on both ends of your intense training, androgenic vs estrogenic steroids. (tdtraktorist.ru)
It measures the percentage of blood sugar attached to hemoglobin (the protein which carries oxygen in your blood cells). (whitelotusclinic.ca)
A gene in the sex-determining region of the short arm of the Y, now referred to as SRY , has been found to direct production of a protein which binds to DNA, inducing differentiation of cells derived from the genital ridges into testes. (en-academic.com)
In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (lookformedical.com)

And ESPECIALLY not for ovarian hormones like estradiol and progesterone. (drfionand.com)

Dazl can regulate the expression, transport and localization of target mRNAs of proteins which control the differentiation, growth and maturation of germ cells. (ijbs.com)

They also produce peptides involved in ovarian hormone synthesis regulation. (wikipedia.org)

Although this level of plasticity is still found in the fully differentiated gonads, errors like mutations or epigenetic modifications impact ovarian development and, later, folliculogenesis, resulting in infertility. (lidsen.com)

In these situations, the hypothalamus makes the "decision" to stop making ovarian hormones (meaning it decides not ovulate as reproduction would be risky). (drfionand.com)
Insulin gene superfamily hormones regulate cell growth, metabolism, and tissue-specific functions. (phoenixbiotech.net)
These hormones are made in the cell bodies and then transported to the axon terminals. (pharmaceuticalintelligence.com)
The gland consists of numerous cell types, which specialize in making and releasing specific hormones. (pharmaceuticalintelligence.com)

The second ultrasound I took clearly showed my ovarian cyst had disappeared into thin air. (tipsforwoman.com)
It's been almost eight months since my doctor first diagnosed me with a small ovarian cyst. (tipsforwoman.com)

The present study was designed to compare the effects of several statins on growth and steroidogenesis of rat theca-interstitial cells. (uky.edu)

The transfer of the major egg yolk proteins such as Very Low Density Lipoproteins (VLDL) containing essentially apovitellenin and apolipoprotein-B, but also vitellogenins and some other plasma proteins from the blood such as serum albumin to the interstitial fluid of the thecae is possible due to the presence of broad discontinuities in the capillary endothelium. (biomedcentral.com)

One study shows that the endocrine disrupting chemical bisphenol-A works in a fashion that is comparable to diethylstilboestrol at the cell and developmental level and research has clearly shown that many industrial chemicals can affect thyroid function. (hindustantimes.com)
Hormone production happens differently in different endocrine glands(and *inside* of different cells). (drfionand.com)
They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. (lookformedical.com)

Ovarian dysfunction includes a "natural" decline in ovarian function caused by age factors and pathological ovarian function decline caused by pathogenic factors such as radiotherapy, chemotherapy and surgery. (biomedcentral.com)

Molecular mechanism events in the ovarian microenvironment, such as angiogenesis and apoptosis, are complex. (encyclopedia.pub)

More specifically, evidence indicates BPA-mediated disruption of STAR, CYP450scc, and HSD-3β in theca cells and CYP450 aromatase activity in granulosa cells. (desdaughter.com)

Appearance of Leydig cells. (en-academic.com)

Cryopreservation of ovarian tissue is of interest to women who want to preserve their reproductive function beyond the natural limit, or whose reproductive potential is threatened by cancer therapy, for example in hematologic malignancies or breast cancer. (wikipedia.org)
Controlled ovarian hyperstimulation (COH) is one of the pivotal steps in assisted reproductive technology (ART). (biomedcentral.com)

Women carrying this gene have low ovarian reserves and higher risks of having Down syndrome babies, as well as of sons with fragile X. (theconversation.com)
For information on therapeutic regulation of gene expression, see therapeutic gene modulation.Regulation of gene expression includes the processes that cells and viruses use to regulate the way that the information in genes is turned into gene products. (absoluteastronomy.com)
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. (absoluteastronomy.com)
Data suggest that a gene named KISS is important in the development of the LHRH-secreting cells. (diseasesdic.com)
Mutations of this gene are associated with the formation of HEREDITARY BREAST AND OVARIAN CANCER SYNDROME. (lookformedical.com)
Mutations in this gene predispose humans to breast and ovarian cancer. (lookformedical.com)

Other recent studies verified the presence of PAPP-A mRNA in granulosa cells of humans, monkeys, cattle, mice, and pigs. (bioone.org)

However, its effect on the proliferative index of stroma cells was not significant. (biomedcentral.com)

In conclusion, COS could significantly improve the ovarian and immune function of chemotherapy model mice, and improve the survival rate of OGSCs, which provided a preliminary blueprint for further exploring the mechanism of COS in protecting ovarian function. (biomedcentral.com)

An error during these developmental steps in females may lead to defective gonads, affecting the differentiation and/or function of the gonads and the development, differentiation, and maturity of the germ cells. (lidsen.com)

The fluid in the theca spaces is then "filtered" by the basal lamina, which selectively permits the passage of particles depending on their size and their molecular charge [ 9 ]. (biomedcentral.com)

Microplastics have been shown to cause increased oxidative stress, inflammation, altered metabolism leading to cellular damage, which ultimately affects tissue and organismal homeostasis in numerous human cells. (hindustantimes.com)
IR alters glucose metabolism, resulting in an elevation in insulin production by beta-cells. (researchsquare.com)
The malfunctioning of our reproduction is tied to underlying energy dysregulation in our cells, caused by the many factors of our industrialized modern living that are disrupting our ability to metabolize food to energy properly (factors ranging from chronic overconsumption of refined sugars to the metabolism-disrupting chemicals in so many of our products like food storage containers, furniture, makeup, and cleaning supplies). (levelshealth.com)

During the menopausal transition, a reduction in ovarian function results in a number of symptoms. (medscape.com)

Depending on the species, DAZL is expressed in primordial germ cells (PGCs) and/or pre-meiotic and meiotic germ cells of both sexes. (ijbs.com)

A legal alternative to the anabolic steroid anavar, anvarol improves your strength and energy by stimulating phosphocreatine synthesis within. (tabadc.org)

This persons contraception status increases thrombogenicity due to reduced endogenous oestrogen status secondary to germ cells destruction by contraception, over that her consumption of hormonal pills to postpone menstruation further decreases endogenous oestrogen, increased vulnerability for pulmonary thromboembolism. (scirp.org)

Those molecular functions of RAS family proteins exhibit an essential role that co-occurs in the repeated pattern of physiological change during the ovarian cycle. (encyclopedia.pub)

We have gained crucial insights into molecular factors and pathways of the cells generating either the supporting gonadal cells or germ cells of both sexes. (lidsen.com)

The cell membrane or plasma membrane is a biological membrane that separates the interior of all cells from the outside environment. (absoluteastronomy.com)
The cell membrane is selectively permeable to ions and organic molecules and controls the movement of substances in and out of cells. (absoluteastronomy.com)

As aample, when cortisol is produced under stress or in the context of natural circadian rhythms, the pituitary gland releases ACTH and the adrenal zona faciculata cells take in cholesterol using special proteins and use it to make pregnenolone and convert it to cortisol. (drfionand.com)

In the last four decades, transgenic and knockout mouse models have helped to understand the mechanisms of mammalian sex determination, germ cell development, and adult gonad functions. (lidsen.com)

This might affect the ovarian reserve and lead to the diagnosis of infertility later in life. (lidsen.com)
In recent years, the discovery of ovarian germ stem cells (OGSCs) has provided a new research direction for the treatment of female infertility. (biomedcentral.com)

Although some pregnenolone leaks into the circulation, most of it is synthesized from cholesterol *inside* the cell. (drfionand.com)

To investigate molecular mechanisms involved in TNFAIP6 transactivation, the activity of bovine TNFAIP6 promoter was studied in granulosa cell cultures. (appliedbioinfo.com)

We collected 35 an 70 granulosa cell samples from patients cycled with and without rLH supplementation, respectively. (biomedcentral.com)

The moment the preferred serum titer was attained, immune spleens were removed through the mice, dissociated, and fused with SP2 o myeloma cells. (liverxreceptor.com)

2 Deficiency of insulin production or activity results in diabetes mellitus (DM), which can be either type 1 (T1DM) when there is a destruction of the β-cell by an autoimmune process, or type 2 (T2DM) in which there is a failure of the β-cell to produce insulin. (researchsquare.com)

Increased expression of LHR, AR, AMH, and SOX9 is characteristic of granulosa-luteal cells from IVF/ intracytoplasmic sperm injection (ICSI) patients receiving rLH supplementation. (biomedcentral.com)

Anatomy9

Organisms5

Diseases2

Chemicals and Drugs31

Analytical, Diagnostic and Therapeutic Techniques and Equipment6

Phenomena and Processes18

Disciplines and Occupations1

Information Science2

Follicles13

Follicle21

Ovaries4

Corpus luteum5

Ovary9

Interna1

Testosterone6

Androgen3

Proliferation7

Polycystic2

Androgens1

Follicular5

Estrogen synthesis1

Oocyte2

Estrogens1

DHEA4

Somatic cells2

PCOS3

Changes in ovarian1

Fertility2

Stimulation2

Protein9

Estradiol1

Maturation1

Hormone synthesis1

Folliculogenesis1

Hormones4

Cyst2

Steroidogenesis1

Interstitial1

Endocrine3

Dysfunction1

Apoptosis1

Aromatase1

Leydig1

Reproductive2

Gene6

Humans1

Stroma1

Mechanism1

Differentiation1

Basal1

Metabolism3

Reduction1

Primordial1

Steroid1

Endogenous1

Occurs1

Pathways1

Membrane2

ACTH1

Germ cell development1

Infertility2

Cholesterol1

Molecular mechanisms1

Granulosa cell1

Mice1

Production1

Sperm1