Endocardial Cushion DefectsHeart Septal DefectsHeart Septal Defects, VentricularEndocardial CushionsHeart Septal Defects, AtrialHeart Defects, CongenitalHeart ValvesHeart SeptumEndocardiumDown SyndromeTetralogy of FallotFetal HeartAortopulmonary Septal DefectEchocardiographyAbnormalities, MultipleCardiac Surgical ProceduresInfant, NewbornHeartAtrial SeptumMesodermMitral Valve InsufficiencyChromosomes, Human, Pair 21Fetal DiseasesMitral ValveTransforming Growth Factor beta2Heart VentriclesUltrasonography, PrenatalSeptal Occluder DeviceChick EmbryoHeart AtriaGene Expression Regulation, DevelopmentalGestational AgePregnancyRetrospective StudiesMorphogenesisEmbryologyReoperationVersicansTransforming Growth Factor beta3