AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesHealth Care
Cushing SyndromeOsteoporosisAdrenal Cortex DiseasesAdrenal Gland DiseasesPituitary ACTH HypersecretionCarney Complex17-HydroxycorticosteroidsAdrenocorticotropic HormoneSyndromeOsteoporosis, PostmenopausalAdrenalectomyAdrenal Gland NeoplasmsAdrenal Cortex Function TestsEsthesioneuroblastoma, OlfactoryAdrenal Cortex NeoplasmsPituitary NeoplasmsHydrocortisoneCyclic AMP-Dependent Protein Kinase RIalpha SubunitPituitary Function TestsAdrenocortical AdenomaAdrenal GlandsACTH Syndrome, EctopicBone DensityIatrogenic DiseaseHypophysectomyAdenomaBone Density Conservation AgentsAdrenal CortexCorticotropin-Releasing HormoneOsteoporotic FracturesFractures, BoneAbdominal FatObesity, AbdominalDiphosphonatesACTH-Secreting Pituitary AdenomaAbsorptiometry, PhotonFractures, SpontaneousAlendronateBone and BonesBone Diseases, MetabolicPituitary IrradiationDown SyndromeMetabolic Syndrome XFollow-Up StudiesParaganglioma, Extra-AdrenalSpinal FracturesTeriparatideEtidronic AcidBone RemodelingBone ResorptionGlucocorticoidsFemur NeckCentral Serous ChorioretinopathyLumbar VertebraeNephrotic SyndromeCavernous SinusSjogren's SyndromeHip FracturesRisk Factors
Cushing'sHypertensionEtiology of Cushing syndromeHyperthyroidismEndocrineFracturesACTHExcessGlucocorticoidsExogenousFractureHyperparathyroidismDexamethasoneStriaePituitary tumorMetabolicIatrogenicCorticosteroidsHarvey CushingAdenomasDiseaseClinicalRisk for osteoporosisDisordersBonesBone densityMoon faciesTumorCorticosteroidPolycysticPlasma cortisolTreatment for osteoporosisBiochemicalChronicSystemicSecondary
Cushing's82
  • Eddy RL, Jones AL, Gilliland PF, Ibarra JD Jr, Thompson JQ, MacMurry JF Jr. Cushing's syndrome: a prospective study of diagnostic methods. (medscape.com)
  • Limitations of nocturnal salivary cortisol and urine free cortisol in the diagnosis of mild Cushing's syndrome. (medscape.com)
  • Raff H. Utility of salivary cortisol measurements in Cushing's syndrome and adrenal insufficiency. (medscape.com)
  • AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: a novel mechanism in Cushing's syndrome. (medscape.com)
  • Cushing's syndrome from epidural methylprednisolone. (medscape.com)
  • Cushing's syndrome with low levels of serum cortisol: the role of inhaled steroids. (medscape.com)
  • This condition can lead to Cushing's syndrome. (novapublishers.com)
  • The most common cause of Cushing's syndrome is exogenous glucocorticoid use from any administration route, including topical, or inhaled glucocorticoids. (standardofcare.com)
  • Among patients with Cushing's syndrome from excess endogenous production of cortisol, Cushing's disease is the underlying cause in approximately 60 to 70% of patients, independent adrenal production of cortisol in 20 to 30% of patients, and ectopic paraneoplastic neuroendocrine tumors that secrete corticotropin, are the underlying cause in about 6 to 10% of patients. (standardofcare.com)
  • Unilateral, adrenal adenoma, or carcinoma and bilateral micronodular or macro nodular adrenal hyperplasia are the most common causes of Cushing's syndrome due to corticotropin independent, adrenal gland production of cortisol. (standardofcare.com)
  • The most common cause of endogenous Cushing syndrome is Cushing's disease in which a benign pituitary adenoma oversecretes corticotropin. (standardofcare.com)
  • Less than 1% of people with Cushing's syndrome have a tumor that secretes corticotropin releasing hormone. (standardofcare.com)
  • ACTH values greater than 15 to 20 pg/mL are consistent with ACTH-dependent Cushing's syndrome. (standardofcare.com)
  • Pituitary MRI with gadolinium should be performed in all patients with ACTH-dependent Cushing's syndrome. (standardofcare.com)
  • Corticotroph adenomas account for approximately 70% of cases of Cushing's syndrome with iatrogenic hypercortisolism, ectopic corticotropin or corticotropin releasing hormone production and cortisol producing adrenal lesions accounting for the rest. (standardofcare.com)
  • Cushing's syndrome due to endogenous cortisol hyperproduction is very rare, and overlapping clinically with more common diseases such as diabetes, obesity, and polycystic ovarian syndrome. (standardofcare.com)
  • Because Cushing's syndrome is potentially curable, the diagnosis should be pursued in all patients whose clinical course suggests endogenous hypercortisolism. (standardofcare.com)
  • What is Cushing's syndrome and what causes it? (caledphone.com)
  • Cushing's syndrome is a hormonal disorder caused by high levels of the hormone cortisol. (caledphone.com)
  • The most common cause of Cushing's syndrome is the long-term use of glucocorticoid medicines such as prednisone. (caledphone.com)
  • Cushing's syndrome is caused by prolonged exposure to high levels of cortisol. (caledphone.com)
  • Cushing's syndrome can also be caused by taking certain medications, such as prednisone, for a long period of time. (caledphone.com)
  • Anyone taking glucocorticoid medications, such as prednisone, for long periods of time is at risk of developing Cushing's syndrome. (caledphone.com)
  • The best way to prevent Cushing's syndrome is to avoid taking glucocorticoid medications for a long period of time. (caledphone.com)
  • The diagnosis of Cushing's syndrome usually involves a combination of tests, including blood tests and imaging studies. (caledphone.com)
  • Treatment for Cushing's syndrome depends on the cause. (caledphone.com)
  • Living with Cushing's syndrome can be difficult , but there are ways to cope. (caledphone.com)
  • It is also helpful to connect with other people who have Cushing's syndrome and share experiences. (caledphone.com)
  • Cushing's syndrome can lead to serious complications, such as high blood pressure , diabetes, and osteoporosis. (caledphone.com)
  • Living with Cushing's syndrome can be challenging, but with proper treatment and support , it is possible to lead a full and healthy life. (caledphone.com)
  • RePub, Erasmus University Repository: The European Registry on Cushing's syndrome: 2-Year experience. (eur.nl)
  • Objective: The European Registry on Cushing's syndrome (ERCUSYN) is designed to collect prospective and follow-up data at EU level on Cushing's syndrome (CS). (eur.nl)
  • What are the symptoms of the Cushing's syndrome? (houstonendocrinecenter.com)
  • Cushing's syndrome is a rare hormonal disease that occurs when the body's tissues are exposed to high cortisol levels for an extended period. (houstonendocrinecenter.com)
  • In this blog, we'll explore the symptoms of Cushing's syndrome. (houstonendocrinecenter.com)
  • One of the most common symptoms of Cushing's syndrome is weight gain, particularly around the abdomen, face, and neck. (houstonendocrinecenter.com)
  • Individuals with Cushing's syndrome may also develop a round, moon-shaped face, often called a "buffalo hump. (houstonendocrinecenter.com)
  • Individuals with Cushing's syndrome may experience headaches, dizziness, and blurred vision, all associated with high blood pressure. (houstonendocrinecenter.com)
  • Cortisol affects brain function, and individuals with Cushing's syndrome may experience mood changes, such as anxiety, depression, and irritability. (houstonendocrinecenter.com)
  • Individuals with Cushing's syndrome may experience thinning skin, easy bruising, and slow wound healing. (houstonendocrinecenter.com)
  • Women with Cushing's syndrome may experience menstrual irregularities, including heavy or prolonged periods or no periods at all. (houstonendocrinecenter.com)
  • Berry, M. (1995) Healing of osteoporotic vertebral compression fractures following cure of Cushing's syndrome Australasian Radiology, 39 (2). (ias.ac.in)
  • A young boy with endogenous Cushing's syndrome with severe osteoporosis, demonstrating satisfactory recovery of osteoporotic changes within 2 years after cure of Cushing's syndrome, is described. (ias.ac.in)
  • Endogenous' suppression of the adrenal cortex may occur in patients with structural abnormalities affecting the hypothalamus/pituitary and in other patients with deficiency of pituitary ACTH secretion and action including those recovering from successful treatment of Cushing's syndromes. (endocrine-abstracts.org)
  • Cushing's syndrome describes the signs and symptoms associated with prolonged exposure to inappropriately high levels of the hormone cortisol. (dailymeded.com)
  • Cushing's disease refers to a pituitary-dependent cause of Cushing's syndrome: a tumor (adenoma) in the pituitary gland produces large amounts of ACTH, causing the adrenal glands to produce elevated levels of cortisol. (dailymeded.com)
  • It is the most common non-iatrogenic cause of Cushing's syndrome, responsible for 70% of cases excluding glucocorticoid related cases. (dailymeded.com)
  • Exogenous (iatrogenic) steroids, such as glucocorticoid drugs are the number one cause of Cushing's syndrome. (dailymeded.com)
  • Cushing's syndrome is also a common cause of anovulation. (dailymeded.com)
  • Dexamethasone suppression test, is a test that is done to differentiate between different causes of Cushing's syndrome. (dailymeded.com)
  • Most Cushing's syndrome cases are caused exogenous steroid medications (iatrogenic). (dailymeded.com)
  • Women taking medication for Cushing's syndrome may not receive adequate birth control protection from Depo Provera. (targetwoman.com)
  • Excessive corticosteroid intake can lead to a collection of symptoms known as Cushing's syndrome, characterized by weight gain, moon face, and increased susceptibility to infections. (prednisone2.us)
  • But lest we be accused of being safely predictable, this year Pharm Exec decided to focus, too, on clinical and marketing achievement for an orphan-status rare disease drug, calling out Bay area start-up Corcept Therapeutics' initiative in repurposing an old drug, mifepristone, for a new indication as the first treatment for Cushing's syndrome, a disabling metabolic disorder that is habitually underdiagnosed. (pharmexec.com)
  • The most common cause of Cushing's syndrome is iatrogenic from medically prescribed corticosteroids. (endocrine.org)
  • Testing for Cushing's syndrome in certain high-risk populations has shown an unexpectedly high incidence of unrecognized Cushing's syndrome as compared with the general population. (endocrine.org)
  • Because Cushing's syndrome tends to progress, accumulation of new features increases the probability that the syndrome is present. (endocrine.org)
  • Caregivers are encouraged to consider Cushing's syndrome as a secondary cause of these conditions, particularly if additional features of the disorder are present. (endocrine.org)
  • If Cushing's syndrome is not considered, the diagnosis is all too often delayed. (endocrine.org)
  • 3.1 We recommend obtaining a thorough drug history to exclude excessive exogenous glucocorticoid exposure leading to iatrogenic Cushing's syndrome before conducting biochemical testing. (endocrine.org)
  • 3.3 We recommend against widespread testing for Cushing's syndrome in any other patient group. (endocrine.org)
  • 3.6 In individuals with normal test results in whom the pretest probability is high (patients with clinical features suggestive of Cushing's syndrome and adrenal incidentaloma or suspected cyclic hypercortisolism), we recommend further evaluation by an endocrinologist to confirm or exclude the diagnosis. (endocrine.org)
  • 3.7 In other individuals with normal test results (in whom Cushing's syndrome is very unlikely), we suggest reevaluation in 6 months if signs or symptoms progress. (endocrine.org)
  • 3.8 In individuals with at least one abnormal test result (for whom the results could be falsely positive or indicate Cushing's syndrome), we recommend further evaluation by an endocrinologist to confirm or exclude the diagnosis. (endocrine.org)
  • Osteoporosis may be primary or secondary to an underlying disease, such as Cushing's syndrome or hyperthyroidism. (medicscientist.com)
  • disease or Itsenko-Cushing's syndrome. (healthtwentyfour.com)
  • Causes and pathophysiology of Cushing's syndrome. (wikem.org)
  • What Is Cushing's Syndrome and Why Should We Be Concerned About It? (futureofpersonalhealth.com)
  • Approximately 25,000 Americans are living with Cushing's syndrome but our understanding of the disease is still lacking. (futureofpersonalhealth.com)
  • Can you give a brief overview on what Cushing's syndrome is? (futureofpersonalhealth.com)
  • Cushing's syndrome is a rare endocrine disorder that is usually not inherited and typically affects adults. (futureofpersonalhealth.com)
  • For people who do not have Cushing's syndrome, the highest levels of cortisol are secreted into the blood in the first hour after waking in the morning, with additional cortisol secreted in bursts at any time of day or night in response to external stresses, like infections, surgery, and trauma, or internal stresses like fear and anxiety. (futureofpersonalhealth.com)
  • For those with endogenous Cushing's syndrome, the adrenal glands secrete cortisol in a disordered way throughout the day and night, not in response to stress, but due to an internal cause, usually because a tumor is driving the excessive production of cortisol. (futureofpersonalhealth.com)
  • When a pituitary tumor causes the excess cortisol production, it's called Cushing's disease which accounts for more than 70% of Cushing's syndrome in adults in the U.S. Other causes of Cushing's syndrome are tumors in the adrenal glands themselves or in very rare cases, tumors that can secrete ACTH outside of the pituitary. (futureofpersonalhealth.com)
  • Endogenous Cushing's syndrome is different from exogenous Cushing's syndrome based on what causes the production of excess cortisol. (futureofpersonalhealth.com)
  • Exogenous Cushing's syndrome is caused by medicines that are intended to deliver cortisol-like hormones as therapy (drugs like prednisone, fluticasone, etc. (futureofpersonalhealth.com)
  • If given in sufficiently high doses for a period of time, these medicines can cause exogenous Cushing's syndrome. (futureofpersonalhealth.com)
  • Signs and symptoms of Cushing's syndrome vary widely and can mimic much more common conditions, such as the common forms of obesity, Type-2 diabetes, high blood pressure, and polycystic ovary syndrome, which makes diagnosing it challenging. (futureofpersonalhealth.com)
  • About how many people are affected by endogenous Cushing's syndrome? (futureofpersonalhealth.com)
  • In the United States, approximately 25,000 adults are diagnosed with endogenous Cushing's syndrome. (futureofpersonalhealth.com)
  • Over time, the excess cortisol secretion characteristic of Cushing's syndrome can lead to problems with essentially every system in the body, from the blood to the brain, from the immune to digestive system. (futureofpersonalhealth.com)
  • Commonly, though, people with Cushing's syndrome tend to suffer from excessive weight gain or difficulty maintaining normal weight, high blood pressure, obstructive sleep apnea, diabetes or prediabetes, changes in mood (heightened emotions/irritability/depression), insomnia, anxiety, or mood changes. (futureofpersonalhealth.com)
Hypertension5
  • All patients with incidental adrenal mass should also be evaluated for subclinical Cushing syndrome, a condition characterized by adrenocorticotropic hormone-independent cortisol secretion that may cause metabolic (hyperglycemia and hypertension) and bone (osteoporosis) effects of hypercortisolism, but not the more specific clinical features of Cushing syndrome, such as supraclavicular fat pads, wide violaceous striae, facial plethora, and proximal muscle weakness. (acponline.org)
  • Weight gain, hypertension, and hypokalemia are non-specific features of Cushing syndrome. (standardofcare.com)
  • The seminal studies of Harvey Cushing informed us of the deleterious consequences of circulating cortisol excess hypertension, osteoporosis and obesity that contributes to diabetes and premature mortality. (endocrine-abstracts.org)
  • Disorders leading to PCS usually are associated with systemic complications, mainly of a metabolic/cardiovascular nature (eg, hypertension, insulin resistance, diabetes mellitus, coronary heart disease, osteoporosis), which are also present in CS. (medscape.com)
  • Treatment should be planned and supervised bearing in mind the more serious side effects of corticosteroids in old age, particularly diabetes, hypertension, osteoporosis and susceptibility to infection and thinning of skin. (medscape.co.uk)
Etiology of Cushing syndrome2
Hyperthyroidism1
  • Other endocrine disorders would include hyperthyroidism, hypothyroidism, thyroid nodules, hypoglycemia and metabolic bone diseases such as osteopenia/osteoporosis and Paget disease. (memorial.org)
Endocrine2
  • Cushing syndrome , named after the famous neurosurgeon, Harvey Cushing who first described it, is an endocrine disorder with elevated cortisol levels in the blood. (osmosis.org)
  • McCune-Albright syndrome (MAS) consists of at least two of the following three features: (1) polyostotic fibrous dysplasia (PFD), (2) café-au-lait skin pigmentation (see the image below), and (3) autonomous endocrine hyperfunction (eg, gonadotropin-independent precocious puberty ). (medscape.com)
Fractures10
  • Osteoporosis is a disease that causes bones to become less dense and more prone to fractures. (nuh.com.sg)
  • Not all fractures are due to osteoporosis. (nuh.com.sg)
  • Building healthy bones by adopting healthy nutritional and lifestyle habits in childhood is important to help prevent osteoporosis and fractures later in life. (nuh.com.sg)
  • Osteoporosis , a disease that leads to bone loss which subsequently increases your risk for fractures. (memorial.org)
  • It can also lead to osteoporosis , a situation where the bones become fragile and breakable, increasing the risk of fractures. (houstonendocrinecenter.com)
  • Osteoporosis can lead to broken bones (fractures) in the hip, spine, and wrist. (medicalrecords.com)
  • It's important to find and treat osteoporosis early to prevent bone fractures. (medicalrecords.com)
  • A BMD test can tell you whether or not you have osteoporosis and how likely you are to develop it in the future, and can help you to make decisions that may prevent fractures or further bone loss. (osteoporosis.ca)
  • BMD testing is not usually recommended in younger men or women (under age 50) unless there is a medical condition predisposing them to osteoporosis or when there are unexplained fragility fractures . (osteoporosis.ca)
  • Osteoporosis is a systemic disease of the skeleton, characterized by a decrease in bone mass (BMD) and a violation of its quality (microarchitectonics), which lead to fragility of bones and subsequent fractures with minor trauma (for example, falling from a height of their own growth). (healthtwentyfour.com)
ACTH8
Excess3
  • The excess of the hormone also leads to bone autolysis, which leads to osteoporosis and accelerates the basic rhythm recorded during electroencephalography, causes mental disorders. (novapublishers.com)
  • Cushing syndrome results from prolonged elevated plasma cortisol levels due to either exogenous steroid use, or to excess endogenous cortisol production. (standardofcare.com)
  • Cushing syndrome from excess endogenous cortisol production may also be caused by a benign or malignant adrenal tumor that secretes cortisol or by a benign or malignant non-pituitary corticotropin secreting tumor. (standardofcare.com)
Glucocorticoids1
Exogenous1
Fracture8
  • Our Osteoporosis Care Pack is very beneficial as it strengthens the bone .It also lower the risk of bones fracture that is, it helps the bone from loss. (planetayurveda.com)
  • Osteoporosis only causes symptoms or impact on the patient when there is a fracture, so fracture outcome data takes precedence over bone density data in guiding clinical practice. (racgp.org.au)
  • Osteoporosis is a disease in which bones become fragile and more likely to break (fracture). (adam.com)
  • Osteoporosis, or weak bones, is a disease that causes bones to become brittle and more likely to fracture (break). (adam.com)
  • We now have a much better understanding of the many factors that affect your bone health and influence your chances for excessive bone loss, osteoporosis or experiencing a fracture. (womenshealthnetwork.com)
  • As you begin to understand the real causes of osteoporosis and fracture, it will become clear that you are not doomed to poor bone health just because of your particular demographic. (womenshealthnetwork.com)
  • Osteoporosis has no symptoms until the first fracture takes place. (ubuntumedical.com.au)
  • The treatment for osteoporosis is dependent on the risk of having a fracture in the next 10 years based on the results of the bone density test. (ubuntumedical.com.au)
Hyperparathyroidism1
  • Elevated total serum calcium levels are associated with idiopathic hypercalcemia, vitamin D intoxication, hyperparathyroidism, sarcoidosis, pneumocystic carinii pneumonia, and blue diaper syndrome. (cdc.gov)
Dexamethasone1
  • Currently, four methods are accepted for the diagnosis of Cushing syndrome: the urinary free cortisol level, the low-dose dexamethasone suppression test , the evening serum and salivary cortisol level, and the dexamethasone-corticotropin-releasing hormone test . (medscape.com)
Striae5
Pituitary tumor1
  • [ 1 , 2 ] Hypogonadism that is caused by intrinsic structural, destructive, or congenital pathology of the hypothalamic-pituitary-testicular (HPT) axis (such as pituitary tumor or Klinefelter syndrome) is referred to as organic (also termed classical) hypogonadism (Fig. 1). (medscape.com)
Metabolic5
  • Endocrinologists diagnose and treat a full spectrum of hormone-related conditions and diseases like Type 1 and type 2 diabetes, thyroid disorders, thyroid cancer, osteoporosis, calcium disorders, and a range of metabolic, pituitary and adrenal disorders. (memorial.org)
  • As such Cushing s syndrome offers an excellent paradigm for the metabolic syndrome. (endocrine-abstracts.org)
  • However circulating cortisol concentrations are invariably normal in patients with metabolic syndrome. (endocrine-abstracts.org)
  • Osteoporosis is a metabolic bone disorder in which the rate of bone resorption accelerates while the rate of bone formation slows, causing a loss of bone mass. (medicscientist.com)
  • HbA1c greater than or equal to 6.5%]) or 2 out of 4 components of metabolic syndrome (obesity, dyslipidemia, elevated blood pressure, elevated fasting glucose). (who.int)
Iatrogenic4
  • Also see Glucocorticoid Therapy and Cushing Syndrome and Iatrogenic Cushing Syndrome . (medscape.com)
  • A study by Álvarez-Hernández et al indicated that the clinical severity index of Cushing syndrome, developed by Sonino et al, while useful in endogenous Cushing syndrome, can also effectively be employed in patients with the iatrogenic form of the condition (specifically, in this report, those who had undergone at least 4 weeks of glucocorticoid treatment for rheumatologic disease). (medscape.com)
  • Conversely iatrogenic Cushing s with concomitant adrenal suppression is seen in the 1% of th. (endocrine-abstracts.org)
  • When inhaled, topical and parenteral steroids are added to this burden, iatrogenic Cushing s becomes a major health issue. (endocrine-abstracts.org)
Corticosteroids1
  • Cushing syndrome is a constellation of clinical abnormalities caused by chronic high blood levels of cortisol or related corticosteroids. (msdmanuals.com)
Harvey Cushing1
  • 100 years have passed since Harvey Cushing linked a basophilic pituitary adenoma to bilateral adrenal hyperplasia, and in doing so elegantly depicted the clinical phenotype of Cushing s syndrome. (endocrine-abstracts.org)
Adenomas3
Disease14
  • The primary therapy for Cushing disease is transsphenoidal surgery, and the primary therapy for adrenal tumors is adrenalectomy. (medscape.com)
  • If you cannot stop taking the medicine because of the disease it is treating, your high blood sugar, high cholesterol levels, and bone thinning or osteoporosis should be closely monitored and treated. (medlineplus.gov)
  • This care package also has some important properties like antibacterial, anti-fungul, antiviral, anti-inflammatory and antioxidating which make it more beneficial for osteoporosis disease. (planetayurveda.com)
  • Any systemic disease that a child has may increase his or her risk of having secondary osteoporosis. (nuh.com.sg)
  • Osteoporosis is the most common type of bone disease. (adam.com)
  • Osteoporosis is a rare disease of the bones. (adam.com)
  • The patient should be evaluated for primary subclinical Cushing disease and pheochromocytoma. (acponline.org)
  • Cushing disease is caused by corticotropin secreting pituitary adenoma is the typically benign and arise from an expansion of corticotroph cells in the anterior pituitary gland. (standardofcare.com)
  • Because many of the symptoms of Cushing syndrome are nonspecific diagnosis of Cushing syndrome may take 3 years and for Cushing disease even longer. (standardofcare.com)
  • Cushing s disease of the kidney occurs in the hyper. (endocrine-abstracts.org)
  • Osteoporosis is a disease that affects your bones. (medicalrecords.com)
  • Because of the high prevalence of alcohol abuse and the possibility that test results may be identical to those in Cushing disease, clinicians should be familiar with this disorder to avoid misdiagnosis and inappropriate therapy. (medscape.com)
  • Osteoporosis, which literally translates to porous (porosis) bone (osteo) , is a disease that diminishes the quality and density of bones. (ubuntumedical.com.au)
  • Osteoporosis usually does not have any underlying medical disease. (ubuntumedical.com.au)
Clinical3
  • This clinical situation is known as Nelson's syndrome. (dailymeded.com)
  • Osteoporosis Canada recommends combining the results of BMD testing with some very important clinical risk factors. (osteoporosis.ca)
  • The clinical presentation of MAS is highly variable, depending on which of the various potential components of the syndrome predominate. (medscape.com)
Risk for osteoporosis4
Disorders1
  • Although there are limited data on the prevalence of the syndrome in these disorders, the diagnosis should be considered. (endocrine.org)
Bones4
Bone density5
Moon facies1
Tumor1
Corticosteroid1
Polycystic3
  • What is the main cause of polycystic ovary syndrome? (caledphone.com)
  • Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. (medscape.com)
  • Metformin and combined oral contraceptive pills in the management of polycystic ovary syndrome: a systematic review and meta-analysis. (medscape.com)
Plasma cortisol1
  • Sutinen et al reported that highly active antiretroviral therapy (HAART) in patients infected with human immunodeficiency virus (HIV) is associated with a poorly understood lipodystrophy and hypertriglyceridemia, which resembles Cushing syndrome, but in which plasma cortisol is not elevated. (medscape.com)
Treatment for osteoporosis1
Biochemical3
Chronic1
Systemic1
  • Nuclear factor-kappaB- and glucocorticoid receptor alpha- mediated mechanisms in the regulation of systemic and pulmonary inflammation during sepsis and acute respiratory distress syndrome. (medscape.com)
Secondary1