• Diffuse
  • Symptoms: Diffuse joint and bone pain (especially of spine, pelvis, and legs) Muscle weakness Difficulty walking, often with waddling gait Hypocalcemia (positive Chvostek sign) Compressed vertebrae and diminished stature Pelvic flattening Weak, soft bones Easy fracturing Bending of bones Osteomalacia in adults starts insidiously as aches and pains in the lumbar (lower back) region and thighs before spreading to the arms and ribs. (wikipedia.org)
  • congenital
  • When doctors consider slip disks they often look through etiology, which includes neck and back strains, trauma, congenital/inborn bone malformation, heavy lifting, degenerated disks, and/or weakness of ligaments. (blogspot.com)
  • phosphate
  • Serum bone formation markers were high: osteocalcin 52 ng/mL (reference range 4-12 ng/mL), alkaline phosphatase 23 μg/L (reference range 7.5-17 μg/L), and bone-specific alkaline phosphatase 36.5 μg/L (reference range 7.5-17 g/L). Tubular reabsorption of phosphate measured by ratio of the renal tubular maximum reabsorption rate of phosphate to the glomerular filtration rate (TmP/GFR) was normal initially ( Fig 3 ). (aappublications.org)
  • chronic
  • Most of the time, the only alleged symptom is chronic fatigue, while bone aches are not spontaneous but only revealed by pressure or shocks. (wikipedia.org)
  • density
  • Being out in the sun, taking around 10,000 IU of Vitamin D for up to 8 weeks, and drinking more milk would help keep the bones from loosing more strength and density. (naturalheightgrowth.com)
  • cells
  • In the formation stage, cells called osteoblasts build new bone to replace the old. (thefreedictionary.com)
  • A paracrine role for la,25(OH)2 D3 has been suggested by the combined presence of enzymes capable of oxidizing vitamin D3 into its active forms, e.g., 25-OHD-la-hydroxylase, and specific receptors in several tissues such as bone, keratinocytes, placenta, and immune cells. (allindianpatents.com)