• A subungual osteochondroma is rare, but it is particularly prone to a painful bursa (not visible on plain radiographs) and fracture. (medscape.com)
  • When used in the phrases "cartilaginous exostosis" or "osteocartilaginous exostosis", the term is considered synonymous with osteochondroma. (wikipedia.org)
  • An osteochondroma is a cartilage-covered bony excrescence (exostosis) that arises from the surface of a bone. (medscape.com)
  • Subungual tumor, osteochondroma, subungual exostosis. (faoj.org)
  • Osteochondromas are similar to the subungual exostosis under the hallux nail plate. (faoj.org)
  • Histologically, the subungual exostosis has a fibrocartilage cap whereas the osteochondroma has distinctive hyaline cartilage. (faoj.org)
  • Hereditary multiple exostoses (HME), also called hereditary multiple osteochondromas (HMO), is a condition that is estimated to affect 1 in 50,000 individuals. (wikipedia.org)
  • Hereditary multiple exostoses (HME), also known as osteochondromatosis, is the presence of multiple osteochondromas. (medscape.com)
  • 15% occur as multiple lesions associated with hereditary multiple osteochondromas (HME). (medscape.com)
  • Hereditary multiple exostoses, also known as osteochondromatosis, is an inherited, autosomal dominant disorder in which multiple osteochondromas are seen throughout the skeleton. (medscape.com)
  • Multiple hereditary exostoses (MHE) also known as Multiple Osteochondromas is a rare benign bone tumour disease, characterized by multiple osteocartilaginous masses. (mattioli1885journals.com)
  • 6.Grzelecki D, Szneider J, Marczak D, Kowalczewski J. Total knee arthroplasty with simultaneous tibial shaft osteotomy in patient with multiple hereditary osteochondromas and multiaxial limb deformity - a case report. (mattioli1885journals.com)
  • Skeletal OCs or osteocartilaginous exostoses constitute 10-15% of all bone tumors [1]. (jocr.co.in)
  • BACKGROUND: Solitary osteochondromas, or osteocartilaginous exostoses (OCEs), represent the most common benign bone tumor. (bvsalud.org)
  • This study supports application of a standardized measuring technique for improved distinction of benign osteochondromas from chondrosarcomas, with a cartilage cap thickness of 2 cm or greater as the determinant of chondrosarcoma. (rsna.org)
  • To validate a technique for reproducible measurement of the osteochondroma cartilage cap with computed tomography (CT) and magnetic resonance (MR) imaging and to reevaluate the correlation of the thickness of the cartilage cap with pathologic findings to improve noninvasive differentiation of benign osteochondromas from secondary chondrosarcomas. (rsna.org)
  • In less than 1% of all solitary osteochondromas, malignant degeneration of the cartilage cap is usually heralded by new onset of growth, pain and rapid growth of the lesion. (faoj.org)
  • Osteochondromas , which are the most common bone tumors in children, may be solitary or multiple, and they may arise spontaneously or as a result of previous osseous trauma. (medscape.com)
  • Most solitary osteochondromas are discovered incidentally in children and adolescents. (medscape.com)
  • Plain radiograph of the cervical spine shows a solitary osteochondroma of the posterior elements of C6. (medscape.com)
  • The true prevalence of solitary osteochondromas is not known, because many asymptomatic lesions go undiagnosed. (medscape.com)
  • Most osteochondromas, solitary or multiple, arise from tubular bones and are metaphyseal in location. (medscape.com)
  • CONCLUSIONS: In our large cohort of pediatric patients who underwent excision of solitary knee osteochondromas, most patients were male adolescent athletes. (bvsalud.org)
  • Solitary osteochondromas account for 35 to 40 percent of all benign bone tumors. (faoj.org)
  • Malignant transformation to osteogenic sarcoma has also been reported, but not in solitary, subungual osteochondromas. (faoj.org)
  • 6 months or requiring reoperation), which were more common in patients with sessile osteochondromas (p = 0.01), younger age (p = 0.01), and distal femoral lesions as compared with proximal tibial lesions (p = 0.003). (bvsalud.org)
  • Radiographs of both hands of 36-year-old man show multiple osteochondromas involving the radii right distal fibula, metacarpals, and phalanges. (medscape.com)
  • An isolated osteochondroma is usually associated with trauma, especially in the distal phalanx of the hallux. (faoj.org)
  • Osteochondroma (OC) is the most common benign tumor of the skeleton. (jocr.co.in)
  • Osteochondroma is the most common benign bone tumor of the foot. (faoj.org)
  • [ 1 , 2 ] Osteochondromas account for 20-50% of benign bone tumors and 9% of all bone tumors. (medscape.com)
  • Osteochondroma (OC) is the most common bone tumor, which constitutes 20-50% of all benign bone tumors [1]. (jocr.co.in)
  • 4] Osteochondromas rarely become malignant and mitotic figures are rarely identified microscopically. (faoj.org)
  • The overall prevalence rates for specific tumor types were 7.5% for nonossifying fibromas, 5.2% for enostoses, 4.5% for osteochondromas, and 1.8% for enchondromas. (bvsalud.org)
  • An osteochondroma can affect any bone preformed in cartilage. (medscape.com)
  • An osteochondroma of the sesamoid bone of the hallux has been described, but it is extremely rare. (medscape.com)
  • After initial excision, a revisional surgery was performed one year later that included more aggressive curettage of the recurrent osteochondroma with allogenic bone grafting using InterGro® DBM Plus. (faoj.org)
  • Osteochondromas are small, benign, bone neoplasms and are the most common bone tumor of the foot. (faoj.org)
  • 2] Unlike osteochondromas that originate from the metaphyseal surface of the bone, enchondromas occur deep within the spongiosa of bone. (faoj.org)
  • In long bones, osteochondromas are typically located at the metaphysis. (medscape.com)
  • Osteochondromas arise less frequently from flat bones than from long bones. (medscape.com)
  • Multiple osteochondromas (MO) is a rare disorder, characterized by benign osteocartilaginous tumors (osteochondromas), arising from the perichondrium of bones. (bvsalud.org)
  • HME is associated with a loss-of-function type of mutation in the tumor suppressor genes exostosin-1 and -2 ( EXT1 and EXT2), which are responsible for the synthesis of heparan sulfate proteoglycans (HSPG), resulting in HSPG deficiency and subsequent development of multiple osteochondromas. (medscape.com)
  • Our study aims to analyze the data captured by the Registry of Multiple Osteochondromas, to refine Istituto Ortopedico Rizzoli (IOR) Classification, providing a representative picture of the phenotypic manifestations throughout the lifespan. (bvsalud.org)
  • Takagi M, Kiyoshige Y, Ishikawa A, Ogino T. Multiple occurrence of osteochondromas in dysplasia epiphysealis hemimelica. (medscape.com)
  • Agreement between measurements with CT and MR imaging was also evaluated, as were the sensitivity and specificity of both modalities for differentiation of osteochondromas from chondrosarcomas. (rsna.org)
  • With 2 cm used as a cutoff for distinguishing benign osteochondromas from chondrosarcomas, the sensitivities and specificities were 100% and 98% for MR imaging and 100% and 95% for CT, respectively. (rsna.org)
  • Osteochondromas arising from the pelvis are commonly large and are typically associated with a soft-tissue mass that may grow outward or inward, displacing adjacent structures. (medscape.com)
  • The osteochondromas increase during growth, frequently causing deformities and limitations. (bvsalud.org)
  • The most common site of origin for an osteochondroma is the metaphysis at bony sites of tendon and ligamentous attachments. (medscape.com)
  • 3. [Osteochondroma and multiple osteochondromas: recommendations on the diagnostics and follow-up with special consideration to the occurrence of secondary chondrosarcoma]. (nih.gov)
  • 10. Secondary chondrosarcoma in osteochondroma: report of 107 patients. (nih.gov)
  • 14. Intraosseous atypical chondroid tumor or chondrosarcoma grade 1 in patients with multiple osteochondromas. (nih.gov)
  • Osteochondroma is a benign, cartilaginous neoplasm that is found in any bone that undergoes enchondral bone formation in its development. (medscape.com)
  • The World Health Organization (WHO) defines osteochondroma as a cartilage-capped bony projection on the external surface of a bone. (medscape.com)
  • A subungual osteochondroma is rare, but it is particularly prone to a painful bursa (not visible on plain radiographs) and fracture. (medscape.com)
  • Subungual melanoma with osteocartilaginous differentiation. (ox.ac.uk)
  • Osteocartilaginous metaplasia is known to occur rarely in melanomas, particularly in subungual melanomas. (ox.ac.uk)
  • In long bones, osteochondromas are typically located at the metaphysis. (medscape.com)
  • Osteochondromas arise less frequently from flat bones than from long bones. (medscape.com)
  • 15% occur as multiple lesions associated with hereditary multiple osteochondromas (HME). (medscape.com)
  • As benign lesions, osteochondromas have no propensity for metastasis. (medscape.com)
  • The most common site of origin for an osteochondroma is the metaphysis at bony sites of tendon and ligamentous attachments. (medscape.com)
  • Osteochondromas can be associated with a reduction in skeletal growth, bony deformity, restricted joint motion, shortened stature, premature osteoarthrosis, and compression of peripheral nerves. (nih.gov)
  • Osteochondromas can occur in many different locations in the body. (medscape.com)
  • 15. Manifestations and management of osteochondromas: a retrospective analysis of 382 patients. (nih.gov)
  • Diagnostic radiological and histological features and the nature of the osteocartilaginous differentiation within this lesion is discussed. (ox.ac.uk)
  • 16] Thus, it is possible that regulation of miRNA expression may eventually become part of the treatment of osteochondroma. (medscape.com)