IbuprofenNSAIDsNonsteroidal anti-Rheumatoid arthritis and osteoarthritisNaproxenInflammationDiclofenacSpondylitis100mgPostoperative painContains ketoprofenAnalgesic and anti-inflammatoryAnti-inflammatory propertiesAcute painPsoriatic ArthritisSymptoms of osteoarthritisAcetaminophenNSAIDDegenerative joint dAspirinArthritisInflammatoryMusculoskeletalSprainsProstaglandin synthesisStiffnessSevereKneeTopicalDysplasiaDoseMetabolismCyclooxygenaseKidneysExcretionTopicallyJoint painCochraneEfficacyMethotrexatePregnancy
Ibuprofen12
- A 2013 systematic review indicated "The efficacy of orally administered ketoprofen in relieving moderate-severe pain and improving functional status and general condition was significantly better than that of ibuprofen and/or diclofenac. (wikipedia.org)
- A 2017 Cochrane systematic review investigating ketoprofen as a single-dose by mouth in acute, moderate-to-severe postoperative pain concluded that its efficacy is equivalent to drugs such as ibuprofen and diclofenac. (wikipedia.org)
- With analysis by drug (at least three trials), ketoprofen (number needed to treat 2.6), felbinac (3.0), ibuprofen (3.5), and piroxicam (4.2) had significant efficacy. (bmj.com)
- Fenoprofen (fen" oh proe' fen) belongs to the propionic derivative class of NSAIDs similar to naproxen, ketoprofen, flurbiprofen and ibuprofen. (nih.gov)
- Patients with fenoprofen induced liver injury should avoid other propionic acid derivatives such as flurbiprofen, ibuprofen, ketoprofen and naproxen. (nih.gov)
- Rimadyl ® (carprofen) is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that includes ibuprofen, naproxen, and ketoprofen. (petsupplies4less.com)
- Like many NSAIDs, it falls under the same propionic acid class as ibuprofen and ketoprofen. (medi-vet.com)
- Limited evidence of efficacy, potentially subject to publication bias, existed for topical preparations of ibuprofen gels and creams, unspecified diclofenac formulations and diclofenac gel other than Emulgel, indomethacin, and ketoprofen plaster in acute pain conditions, and for salicylate rubefacients for chronic pain conditions. (unboundmedicine.com)
- Several other nonopioid analgesics (such as ibuprofen , ketoprofen , and naproxen ) are available OTC, but higher doses may require a prescription. (msdmanuals.com)
- Four of the 5 active ingredients (aspirin, ibuprofen, ketoprofen, and naproxen sodium) are nonsteroidal anti-inflammatory drugs (NSAIDs) and can reduce inflammation (swelling) at doses higher than those recommended for OTC use. (bigcdiscountdrugs.com)
- You should not substitute acetaminophen, ibuprofen, ketoprofen, or naproxen sodium for aspirin if you are using it to reduce your risk of a heart attack. (bigcdiscountdrugs.com)
- Prescription ibuprofen is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). (planetdrugsdirect.com)
NSAIDs3
- Ketoprofen belongs to the group of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). (pocketpills.com)
- Ketoprofen, like other NSAIDs, may reduce the excretion of methotrexate and help to increase its toxicity. (pharmru.com)
- NSAIDs can be used as anti-inflammatory agents in musculoskeletal disorders, such as rheumatoid arthritis and osteoarthritis. (pharmacampus.in)
Nonsteroidal anti-1
- Ketoprofen is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. (wikipedia.org)
Rheumatoid arthritis and osteoarthritis2
- The recommended adult dose for rheumatoid arthritis and osteoarthritis is 150 mg to 200 mg daily. (pocketpills.com)
- These include rheumatoid arthritis and osteoarthritis. (ucihealth.org)
Naproxen1
- Prescription naproxen is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), juvenile arthritis (a form of joint disease in children), and ankylosing spondylitis (arthritis that mainly affects the spine). (medlineplus.gov)
Inflammation7
- Ketoprofen is generally prescribed for arthritis-related inflammatory pains or severe toothaches that result in the inflammation of the gums. (wikipedia.org)
- Ketoprofen is indicated for relief of mild-to-moderate pain and inflammation. (medscape.com)
- After the very early stages of osteoarthritis, inflammation begins to play a role in the disease. (medscape.com)
- Ketoprofen relieves pain and reduces swelling and inflammation by reducing a substance in the body that leads to inflammation and pain. (pocketpills.com)
- Rimadyl ® Rx is prescribed to help alleviate the pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs. (petsupplies4less.com)
- Rimadyl ® is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs. (petsupplies4less.com)
- For example, osteoarthritis is painful, but inflammation is usually not present. (bigcdiscountdrugs.com)
Diclofenac1
- The FDA approved a submicron low-dose product (Zorvolex) for osteoarthritis that allows treatment at a lower dose than the diclofenac sodium and potassium salts. (medscape.com)
Spondylitis2
- It is available as a prescription only medicine and is commonly used for Ankylosing Spondylitis, Familial Adenomatous Polyposis, Fibromatosis, Juvenile Rheumatoid Arthritis, Osteoarthritis, Pain, Period Pain. (bistropizzacasa.de)
- It is used for the symptomatic treatment of Rheumatoid Arthritis, osteoarthritis, and ankylosing spondylitis. (pocketpills.com)
100mg1
- Untuk Osteoarthritis & Arthritis rheumatoid Beli Ketoprofen Novel 100mg tab di K24klik dan rasakan manfaatnya. (k24klik.com)
Postoperative pain1
- Topical NSAID in the treatment of acute and chronic pain, of both rheumatic and traumatic origin as well as postoperative pain, including osteoarthritis, tendonitis, muscle strains, sprains, and swelling. (ampharcousa.com)
Contains ketoprofen1
- NIDAL ® gel contains ketoprofen, a phenyl propionic acid derivative of a non-steroid nature with analgesic and anti-inflammatory properties. (ampharcousa.com)
Analgesic and anti-inflammatory1
- Ketoprofen is used for its antipyretic, analgesic, and anti-inflammatory properties by inhibiting cyclooxygenase-1 and -2 (COX-1 and COX-2) enzymes reversibly, which decreases production of proinflammatory prostaglandin precursors. (wikipedia.org)
Anti-inflammatory properties1
- Ketoprofen-Based Polymer-Drug Nanoparticles Provide Anti-Inflammatory Properties to HA/Collagen Hydrogels. (csic.es)
Acute pain1
- Current indications include chronic joint pain due to osteoarthritis and rheumatoid arthritis, as well as mild-to-moderate acute pain. (nih.gov)
Psoriatic Arthritis4
- Psoriatic Arthritis vs. Osteoarthritis: What's the Difference? (healthline.com)
- Psoriatic Arthritis (PsA) vs. Osteoarthritis (OA): Which Is It? (healthline.com)
- Psoriatic arthritis (PsA) and osteoarthritis (OA) are two of the most common forms of arthritis. (healthline.com)
- Psoriatic arthritis and osteoarthritis share some symptoms, but they also have key differences. (healthline.com)
Symptoms of osteoarthritis2
- Symptoms of osteoarthritis begin gradually and worsen slowly over time. (adam.com)
- RELAFEN (nabumetone) is indicated for relief of signs and symptoms of osteoarthritis and rheumatoid arthritis. (rxlist.com)
Acetaminophen2
- An initial trial with acetaminophen is warranted in patients with mild-to-moderate osteoarthritis symptoms who do not derive sufficient relief from nonpharmacologic measures. (medscape.com)
- They are used to relieve osteoarthritis pain when the clinical response to acetaminophen is unsatisfactory. (medscape.com)
NSAID5
- Ketoprofen is a common NSAID, antipyretic, and analgesic used in horses and other equines. (wikipedia.org)
- A NSAID drug most-commonly prescribed for musculoskeletal pain from soft-tissue injury, osteoarthritis or other bone and joint problems. (herts.ac.uk)
- Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID). (famhp.be)
- Vetprofen is a non-steroidal, anti-inflammatory drug (NSAID) that is commonly prescribed for the treatment of pain and swelling in dogs following surgeries and geriatric osteoarthritis complications. (medi-vet.com)
- History of skin allergy to ketoprofen, tiaprofenic acid, fenofibrate, other NSAID or UV blocker or parfumes. (ampharcousa.com)
Degenerative joint d2
Aspirin1
- ketoprofen, aspirin or other salicylic acid drugs with the same time, can not increase the efficacy of gastrointestinal side effects and increased incidence of bleeding tendency. (china.cn)
Arthritis5
- Function and Use: It mainly used to treat rheumatoid arthritis, osteoarthritis and other rheumatic diseases. (china.cn)
- Osteoarthritis (OA) is the most common type of arthritis and knee OA, being highly prevalent, accounts for as much or more lower extremity disability. (journalmedicalthesis.com)
- The medication you use will depend on the severity and type of arthritis that's being treated, but chances are that you're using one of these prescriptions if you have rheumatoid arthritis, gout, or osteoarthritis , which are the three most common types. (naturalarthritistreatments.com)
- It is used for the management of chronic pain caused by osteoarthritis, rheumatoid arthritis, low back pain, and frozen shoulder. (mediestore.com)
- In addition, ketoprofen inhibits lipo-oxygenase, has anti-bradykinin activity, stabilizes lysosomal membranes, and causes significant inhibition of neutrophil activity in patients with rheumatoid arthritis. (bestpharmbuy.com)
Inflammatory6
- In more inflammatory presentations of osteoarthritis, such as knee involvement with effusion, these agents may be used as first-line pharmacologic therapy. (medscape.com)
- ketoprofen,drinking and other non-steroidal anti-inflammatory drugs used in conjunction, will increase the gastrointestinal side effects, but also cause the risk of ulcers. (china.cn)
- Depending on the mechanism of action of drugs in osteoarthritis are divided into painkillers, anti-inflammatory, warming, topically irritating, homeopathic. (vsebolezni.com)
- Carprofen's effective use as an anti-inflammatory treatment for osteoarthritis and hip dysplasia is well-established. (medi-vet.com)
- The main properties of ketoprofen are analgesic, anti-inflammatory and anti-edematous action. (pharmru.com)
- Under inflammatory conditions, ketoprofen nanoparticles (KT NP) can reduce pro-inflammatory markers of macrophages and increase anti-inflammatory cytokines. (csic.es)
Musculoskeletal2
- Ketoprofen topical patches are being used for treatment of musculoskeletal pain. (wikipedia.org)
- There is evidence supporting topical ketoprofen for osteoarthritis but not other chronic musculoskeletal pain. (wikipedia.org)
Sprains1
- Ketoprofen can also be used to treat pain associated with menstrual cramps and for the relief of pain after surgery (including dental surgery), pain after giving birth, and mild to moderate pain associated with sprains and strains. (pocketpills.com)
Prostaglandin synthesis2
- Ketoprofen inhibits the prostaglandin synthesis and the thrombocyte aggregation. (ampharcousa.com)
- The pronounced analgesic effect of ketoprofen is due to two mechanisms: peripheral (indirectly, through suppression of prostaglandin synthesis) and central (due to inhibition of prostaglandin synthesis in the central and peripheral nervoussystem). (bestpharmbuy.com)
Stiffness2
- Patients with osteoarthritis experience pain, stiffness, and limited mobility of the affected joint. (adam.com)
- Regardless of your level of exercise, the passage of time means the classic osteoarthritis symptoms - joint pain and morning stiffness, that worsens over time. (sciencebasedmedicine.org)
Severe1
- Metabolism of ketoprofen not dependent on age, presence of severe renal failure or liver cirrhosis. (pharmru.com)
Knee4
- Others are chronic, typically osteoarthritis of hand or knee, or neuropathic pain. (unboundmedicine.com)
- There will be improvement with combination therapy on pain, range of motion and function in osteoarthritis of knee. (journalmedicalthesis.com)
- Help us formulate a better training approach osteoarthritis of knee management. (journalmedicalthesis.com)
- Plasma and tissue levels of ketoprofen have been measured in 24 patients undergoing knee surgery. (ampharcousa.com)
Topical6
- The EMA confirms the positive benefit / risk balance of ketoprofen-containing medicines for topical use. (famhp.be)
- Following a review of topical formulations of ketoprofen, the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has concluded that the benefit-risk balance of these medicines continues to be positive. (famhp.be)
- Topical formulations of ketoprofen are used to treat minor trauma, tendonitis, small-joint osteoarthritis, acute low-back pain and phlebitis. (famhp.be)
- The Committee recommended that topical ketoprofen should only be used when prescribed by a physician. (famhp.be)
- Questions and answers on the review of the marketing authorisations for topical formulations of ketoprofen. (famhp.be)
- 2. Topical ketoprofen-containing medicines (creams, gels, solutions and plasters) have been available in all Member States except for the Netherlands since 1978. (famhp.be)
Dysplasia1
- Dogs of all ages are subject to the symptoms of hip dysplasia and the resultant osteoarthritis. (oldenglishsheepdogclubofamerica.org)
Dose2
- After repeated percutaneous administration of ketoprofen gel the plasma levels were about 60 fold less (9 - 39 ng/g) than those obtained after a single oral dose of ketoprofen (490 - 3300 ng/g). (ampharcousa.com)
- Bioavailability of ketoprofen after cutaneous administration has been estimated to approximately 5% of the level obtained after an orally administered dose based on urinary excretion data. (ampharcousa.com)
Metabolism1
- Ketoprofen undergoes metabolism in the liver via conjugation with glucuronic acid (glucuronidation) by UGT enzymes, hydroxylation of the benzoyl ring by the CYP3A4 and CYP2C9 enzymes, and reduction of its ketone moiety (a carbonyl functional group, i.e. with carbon-oxygen double bond) by carbonyl reducing enzymes (CREs). (wikipedia.org)
Cyclooxygenase1
- Ketoprofen is one of the most effective inhibitors of cyclooxygenase. (pharmru.com)
Kidneys3
- Ketoprofen is metabolized in the liver to form conjugates that are derived mainly kidneys. (pharmru.com)
- During the III trimester of pregnancy, all prostaglandin inhibitors, including ketoprofen, may have toxic effects on the heart, lungs and kidneys of the fetus. (pharmru.com)
- Ketoprofen is excreted through the kidneys mainly as glucuronide conjugate. (ampharcousa.com)
Excretion1
- Excretion of ketoprofen kidney is slow. (pharmru.com)
Topically1
- Ketoprofen when applied topically in a cream hardly accumulates in the body. (pharmru.com)
Joint pain1
- Osteoarthritis is common - the most frequent cause of joint pain. (sciencebasedmedicine.org)
Cochrane1
- Two Cochrane meta-analyses evaluating tramadol concluded that it is efficacious in neuropathic pain [ 1 ] and pain related to osteoarthritis. (medscape.com)
Efficacy1
- The safety and efficacy of ketoprofen gel in children have not been established. (ampharcousa.com)
Methotrexate1
- ketoprofen should not be used with methotrexate to prevent poisoning. (china.cn)
Pregnancy2
- Since the safety of ketoprofen in pregnant women has not been evaluated, it should avoid the use of ketoprofen in I and II trimesters of pregnancy. (pharmru.com)
- During the first and second trimester, as the safety of ketoprofen in pregnant women has not been evaluated, the use of ketoprofen during the first and second trimester of pregnancy should be avoided. (ampharcousa.com)