Orthopedic bioactive glass bone regeneration. Medical search. Frequent questions

In the past, bone fractures were fixed by the methods of applying metal implants. (encyclopedia.pub)
There are several typical clinical indications for the use of biodegradable implants in orthopedics, which are mostly used for fractures stabilization, osteotomy procedures, bone grafts and fusions [ 6 ] [ 7 ] . (encyclopedia.pub)
Despite advances in orthopaedic materials, the development of drug-eluting bone and joint implants that can sustain the delivery of the drug and maintain the necessary mechanical strength to withstand loading has remained elusive. (nature.com)
They came together to exchange information and informed opinion on developments which affect the design, manufacture, and use of bone implants. (edu.au)
The HA was the primary mineral component of teeth and bone, due to its relatively high Ca/P ratio, its resorption rate was low and it was reported that only 5.4% of HA implants was reduced in rabbit cancellous bone in 6 months [ 14 ]. (biomedcentral.com)
Tissue engineering and regenerative medicine can provide a novel treatment regime based on the use of synthetic biomaterials, which may be constructed into three-dimensional implants and combined with biologics (such as cells and/or bioactive molecules). (edu.au)
Minor orthopedic implants include implants used in shoulder, wrist, ankle and foot joints. (thebusinessresearchcompany.com)
Generic Companies Gain Traction - Following the expiry of patents for implants, around sixteen generic companies have entered the orthopedic replacement implants market in the USA, including Orthosolutions, Covenant Orthopedics, Ortho Direct USA, and Emerge Medical. (thebusinessresearchcompany.com)
These generic orthopedic implant companies' offer lower prices compared to branded implants and are thus a big threat for the big orthopedic devices manufacturers such as Stryker, J&J/DePuy/Synthes, Zimmer/Biomet, Smith & Nephew and Medtronic Spine. (thebusinessresearchcompany.com)
The minor orthopedic replacement implants market is segmented by specialty, and by geography. (thebusinessresearchcompany.com)
North America is the largest market for minor orthopedic replacement implants, accounting for 62.2% of the global market. (thebusinessresearchcompany.com)
¾-TCP/PLGA), coatings (plasma-sprayed, electrochemically deposited or precipitated) on orthopedic and dental implants. (isbweb.org)
a positive immune response can lead to successful biointegration of the implant and (for orthopedic implants) bone remodeling. (medscape.com)
Although the focus of this review is on orthopedic implants, the immune pathologic response is also relevant for cardiac, vascular, gastric, and other surgical implants. (medscape.com)
[ 4 ] The metals most commonly used in orthopedic and dental implants are stainless steel (with nickel), cobalt, chromium, and titanium. (medscape.com)
[ 5 ] It therefore is not surprising that immune response to medical implants is commonly reported in the literature, including hypersensitivity to pacemakers or other cardiovascular devices, endovascular stents and coils, dental implants, and orthopedic hardware (eg, joint replacement prostheses, fracture fixation devices, and pain-relief stimulators). (medscape.com)
However, with the large number of joint replacements performed yearly, the largest group of allergic reactions to implants consists of reactions to orthopedic implants. (medscape.com)
Titanium has been widely used in dental implants and orthopedic implants due to its excellent physical and chemical properties and good biocompatibility. (francis-press.com)
Compositionally graded doped hydroxyapatite coating on titanium using laser and plasma spray deposition for bone implants [J]. Acta Biomater, 2019, 84: 414 423. (francis-press.com)
In several orthopedic and trauma surgeries, bone cement is frequently utilized to fixate implants. (emergenresearch.com)
Subperiosteal implants if the resorption is down to basal bone. (implantsutra.com)
M. Geetha, A. K. Singh, R. Asokamani, A. K. Gogia, Ti based biomaterials, the ultimate choice for orthopaedic implants, Progress in Materials Science 54 (2009) 397-425. (iapchem.org)

In addition, mechanical damage of bone often occurs because of an accident, required surgery and so forth. (encyclopedia.pub)
Internal fixation is required for reconstructive surgery on fractured bone to maintain the anatomic reduction in the fragments and provide stability during the healing process. (encyclopedia.pub)
Effective reconstruction of craniomaxillofacial bone defects caused by trauma, tumor resection, or congenital malformation is a major problem in orthopedic surgery. (hindawi.com)
In trauma and orthopaedic surgery, extended bone loss is associated with considerable technical and physiological issues. (openorthopaedicsjournal.com)
Minor orthopedic joint replacement surgery for shoulder, wrist, ankle and foot is growing because of the high incidence of arthritis and fractures. (thebusinessresearchcompany.com)
Osteoarthritis and rheumatoid arthritis are the major causes for joint replacement surgery including minor orthopedic joints. (thebusinessresearchcompany.com)
Bone cement and adhesive are used during the surgery to firmly anchor the implant to the neighboring bone. (emergenresearch.com)
S. Kurtz, K. Ong, E. Lau, F. Mowat, M. Halpern, Projections of Primary and Revision Hip and Knee Arthroplasty in the United States from 2005 to 2030, The Journal of Bone and Joint Surgery 89 (2007) 780-785. (iapchem.org)

Bioactive glass scaffolds for bone tissue engineering: state of the art and future perspectives. (rjstonline.com)
Low temperature additive manufacturing of three dimensional scaffolds for bone-tissue engineering applications: Processing related challenges and property assessment. (acarindex.com)
10] RuizAguilar C, AguilarReyes EA, OlivaresPinto U. WITHDRAWN: Microstructure and in vitro evaluation of BTCP/Zr02phosphatebased bioactive glass scaffolds for bone tissue engineering[J]. Boletin De La Sociedad Espaáola De Cerámica Y Vidrio, 2019, 165: 111. (francis-press.com)

Recently, several studies have shown that ADSC-derived exosomes can exert similar biological effects as ADSCs and enhance bone regeneration [ 27 , 28 ]. (hindawi.com)
These two factors synergistically enhance bone regeneration (Tatullo et al. (springeropen.com)

By way of this review, a deeper understanding of the basic mechanisms of β-TCP for bone repair will be achieved which will aid in the optimization of strategies to promote bone repair and regeneration. (frontiersin.org)
The main challenge for large bone defect repair and regeneration remains the inadequate recruitment of mesenchymal stem cells (MSCs), reduced vascularization, and decreased growth factors stimulation within the scaffold construct to support cell viability and tissue growth. (frontiersin.org)
Most of these paracrine secretions include soluble factors and exosomes, which regulate the repair and regeneration processes at sites of damage by affecting cell proliferation, migration, and differentiation [ 22 , 23 ]. (hindawi.com)
Our work aims to develop optimal tissue engineered constructs for the repair and regeneration of different types of musculoskeletal tissues, including bone, cartilage and tendon. (edu.au)

14. Temenoff, J.S. and A.G. Mikos, Injectable biodegradable materials for orthopedic tissue engineering. (rjstonline.com)

It is expected that bioactive coatings with hierarchical pore structures will lead to antibacterial activity and cytocompatibility. (fau.eu)
Development of bioactive composite coatings based on combination of PEEK, bioactive glass and Ag nanoparticles with antibacterial properties. (fau.eu)
12] Robertson SF, Bandyopadhyay A, Bose S. Titania nanotube interface to increase adhesion strength of hydroxyapatite Solgel coatings on Ti6Al4V for orthopedic applications [J]. Surf Coat Technol, 2019, 372: 140147. (francis-press.com)

They were initially found in the bone marrow [ 11 ] but can also be found in other tissues, such as adipose, periosteum, muscle, placenta, and trabecular bone [ 12 ]. (hindawi.com)
Electrospun nanocomposite for bone tissues regeneration via osteoconduction, osteoinduction, and osteogenesis. (dokumen.pub)
Bioglasses and glass-ceramics have also been suggested as therapeutic agents for stimulating angiogenesis in soft tissues, but these effects need further evaluation in vivo. (ibecbarcelona.eu)
Thus, the combination of hMSC and calcium-releasing glass-ceramics represents a new strategy to achieve vessel stabilization, a key factor in the revascularization of ischemic tissues. (ibecbarcelona.eu)
By incorporating both human mesenchymal stem cells and glass-ceramic particles in an implantable hydrogel, this study provides insights into the vasculogenic potential in soft tissues of the combined strategies. (ibecbarcelona.eu)
Specific growth factors play important roles in the regeneration process of different tissues. (springeropen.com)
Namely, after the initial development of bioceramics that were just tolerated in the physiological environment, emphasis was shifted towards those able to form direct chemical bonds with the adjacent bones and tissues. (ceramic-science.com)

Bone defects or bone injuries caused by aging, traffic accidents, fractures, or bone tumor resection are among the serious problems in orthopedics because they cause major damage to health and lower the quality of life. (encyclopedia.pub)
Recent advances in developing biocompatible materials for treating bone loss or defects have dramatically changed clinicians' reconstructive armory. (openorthopaedicsjournal.com)
This review summarises the major developments of macroporous bioceramics used mainly for repairing bone defects. (afpm.org.my)
Autologous bone remains the gold standard grafting substrate for bone fusions used for small gaps and critical defects. (ucp.pt)
A total of 14 veterinary clinical cases of appendicular bone defects and maxillary / mandibular bone defects are described. (ucp.pt)
In all clinical cases, the synthetic bone substitute was used to fill bone defects, enhancing bone regeneration and complementing the recommended surgical techniques. (ucp.pt)
The aim of this study is to investigate the osteoconductive property and efficacy of bioactive glass combined with risedronate sodium drug in repairing surgically created bony defects in the mandible. (springeropen.com)

In vivo comparison of a granular and putty form of a sintered and a non-sintered silica-enhanced hydroxyapatite bone substitute material. (uni-rostock.de)
Bone substrates like hydroxyapatite and tricalcium phosphate have been widely used for promoting spinal fusion and reducing the complications caused by autograft. (biomedcentral.com)
Whitlockite had a potential of being a better bone substrate hydroxyapatite and tricalcium phosphate in spinal fusion with low risk of inducing ectopic ossification. (biomedcentral.com)
Hydroxyapatite-glass nanocomposites. (dokumen.pub)
A major weakness of current orthopedic implant materials, for instance sintered hydroxyapatite (HA), is that they exist as a hardened form, requiring the surgeon to fit the surgical site around an implant to the desired shape. (afpm.org.my)
In the present case series, a glass-reinforced hydroxyapatite synthetic bone substitute, with osteoinductive and osteoconductive proprieties, was applied. (ucp.pt)
This synthetic bone substitute comprises the incorporation of P 2 O 5 -CaO glass-based system within a hydroxyapatite matrix, moulded into spherical pellets with 250-500 μm of diameter. (ucp.pt)

The increasing predominance of spine deformities including degenerative disc diseases and technological progress in bone-grafting processes are set to propel the growth of the Spine Biologics Market during the forecast period 2022-2027. (industryarc.com)
The global bone cement & glue market size was USD 1,322.6 Million in 2022 and is expected to register a revenue CAGR of 5.9% during the forecast period. (emergenresearch.com)

Large segmental bone loss and bone resection due to trauma and/or the presence of tumors and cysts often results in a delay in healing or non-union. (frontiersin.org)
Large bone loss as a result of trauma, tumor removal, infection, and developmental congenital disorders, often leads to delayed healing or non-union, and remains a critical challenge for orthopedic surgeons. (frontiersin.org)
This can cause an increase in bone loss, trauma to the surrounding tissue, and longer surgical time. (afpm.org.my)
Journal of Orthopaedic Trauma. (nebraska.edu)

We subsequently discuss how β-TCP can regulate osteogenic processes to aid bone repair/healing, namely osteogenic differentiation of mesenchymal stem cells, formation of blood vessels, release of angiogenic growth factors, and blood clot formation. (frontiersin.org)
To create a favorable osteogenic environment, β-TCP scaffolds have been modified in a number of ways to boost bone healing, including modulating physical features (e.g., pore sizes, porosity and surface roughness), combining with ionic components, and the addition/delivery of growth factors. (frontiersin.org)
The effects of shock wave stimulation of mesenchymal stem cells on proliferation, migration, and differentiation in an injectable gelatin matrix for osteogenic regeneration. (uni-rostock.de)
Spinal fusion is different from bone fracture, the fusion procedure requires bone grafting to add osteogenic potential [ 1 ]. (biomedcentral.com)
In addition to interacting with certain humoral factors that regulate bone homeostasis, VEGF can interact synergistically with osteogenic proteins, such as BMP-2, to promote bone formation and bone healing by enhancing cell recruitment, prolonging cell survival, and increasing angiogenesis. (springeropen.com)
Vascular endothelial growth factor (VEGF) and bone morphogenetic protein-2 (BMP-2) are two key regulators of angiogenesis and osteogenesis and promote the endothelial and osteogenic differentiation of stem cells respectively. (springeropen.com)

More than a million of these procedures of this sort are carried out annually across the globe today, and bone cements are routinely used in most of these procedures. (emergenresearch.com)

Recently, carbon-modified biomaterials for bone tissue engineering have been extensively investigated to potentially revolutionize biomaterials for bone regeneration. (openorthopaedicsjournal.com)
Electrospun biomaterials for bone tissue engineering. (dokumen.pub)
She was awarded with a postdoc fellow from the Ministry of Science at the Technical University of Catalonia in Biomaterials for bone tissue regeneration and since 2010 has been professor at this university. (ibecbarcelona.eu)

It functioned as a space filler in association with standard orthopaedic and odontological procedures of stabilization, promoting a faster bone fusion without any local or systemic adverse reactions. (ucp.pt)
With the ability to overcome drawbacks of current fracture healing approaches, bioadhesives provide an appealing option for applications involving repair, stabilization, and regeneration of bone fractures. (emergenresearch.com)

Additional bone graft substitutes and biologics involve allografts, demineralized bone matrix, bone morphogenetic protein, and bioactive glass. (industryarc.com)
The Spine Biologics Market based on product can be further segmented into Bone Graft Substitutes , Spinal Allografts , Cell-Based Matrix, and Others. (industryarc.com)
The demand for bone graft substitutes is estimated to increase by 30 percent from 2013 to 2020. (edu.au)
However, significant morbidity is associated with the harvesting of autologous bone grafts and, for that reason, alternative bone graft substitutes have been developed. (ucp.pt)

The synergistic effects of the structure and biochemical reactivity provided by BGs coupled with the release of bioactive molecules will promote bone regeneration and osseointegration. (fau.eu)
The fundamental concept combines various tissue engineering elements, most often a scaffold as a supporting matrix in combination with living cells and/or bioactive molecules, to form a tissue engineering construct that repairs or regenerates the diseased or damaged tissue or organ. (edu.au)

In addition, CaP biomaterials have demonstrated bioactive, osteoconductive and sometimes, even osteoinductive properties - properties that make them superior to other types of biomaterials used for similar purposes. (isbweb.org)
The incorporation of osteoinductive factors into scaffolds is usually required to promote sufficient bone regeneration (Egri & Eczacioglu, 2017 ). (springeropen.com)

Research progress of pure titanium implant surface treatment technology to promote bone integration. (francis-press.com)

Consequently, enhancing the adhesion of MSCs, augmenting the release of growth factors, and promoting angiogenic potential of biomaterial scaffolds after implantation are pivotal for successful bone regeneration. (frontiersin.org)
A critical element in the longevity of each replacement is the successful interaction of bone tissue with biomaterial. (edu.au)
To address the diverse interests and areas of expertise related to the subject of bone-biomaterial interaction, a conference in Toronto at the end of 1990 brought together forty scientists from research teams in Canada, Europe, Japan, and the USA, as well as representatives of 23 of the world's major health-care companies. (edu.au)

Patients with osteoporotic fractures often require effective fixation and subsequent bone repair. (bvsalud.org)
Importantly, implementing the orthopedic adhesive is validated as an effective closed-loop management approach in restoring the dysregulated bone homeostasis of osteoporotic fractures. (bvsalud.org)
Demand for repair and joint replacement procedures is driven by aging population, sports injuries, bone-related disorders such as osteoporosis, cartilage and bone tissue degradation, and bone fractures, which is driving revenue growth of the bone cement and glue market. (emergenresearch.com)

Herein, kaempferol-loaded mesoporous bioactive glass nanoparticles (MBGNs)-doped orthopedic adhesives are prepared to assist osteoporotic fracture fixation and restore dysregulated bone homeostasis, including promoting osteoblast formation while inhibiting osteoclastic bone-resorbing activity to synergistically promote osteoporotic fracture healing. (bvsalud.org)

Moreover, Ca2+ and SiO4 4- ions released from MBGNs can accelerate osteogenesis via the PI3K/AKT pathway, while kaempferol mediated osteoclastogenesis inhibition and can slow down the bone resorption process through NF-κB pathway, which regulated bone regeneration and remodeling. (bvsalud.org)
Osteogenesis and angiogenesis are two closely correlated processes during bone growth, development, remodeling, and repair. (springeropen.com)
However, contact osteogenesis can result in bone attachment to the implant surface if the implant has a surface topography with submicron physical undercuts [3]. (toysis.pics)

The 3D-printed scaffold structures are used as supports in replacing and repairing fractured bone tissue. (mdpi.com)
Polymer-Bioactive Glass Composite Filaments for 3D Scaffold Manufacturing by Fused Deposition Modeling: Fabrication and Characterization. (uni-rostock.de)
Apatite formation on the scaffold surface was determined with Simulation body fluid (SBF), and a new bone-like apatite layer shaping on all samples confirmed the in vitro bioactivity of ZSM-5-GEN scaffolds. (afpm.org.my)
This study attempted to assess VEGF and BMP-2 reflecting the effect of hybrid bio-composite scaffold on bone healing in dogs and evaluate the quality of the healing process radiologically. (springeropen.com)

In recent years, electroconductive hydrogels (ECHs) have shown great potential in promoting nerve regeneration and motor function recovery following diabetic peripheral nerve injury (PNI), attributed to their similar electrical and mechanical characteristics to innate nervous tissue. (bvsalud.org)

In this study, the printing capability of two different additive manufacturing (3D printing) techniques, namely PolyJet and micro-stereolithography (µSLA), are investigated regarding the fabrication of bone scaffolds. (mdpi.com)
Printed bone scaffolds with complex structures produced using additive manufacturing technology can mimic the mechanical properties of natural human bone, providing lightweight structures with modifiable porosity levels. (mdpi.com)

Porous structure, biocompatibility and biodegradability, large surface area, and drug-loading ability are some remarkable properties of zeolite structure, making it a great possible option for bone tissue engineering. (afpm.org.my)
Graphene oxide has been increasingly used in the research and development of composite biomaterials due to its good mechanical properties, bone conductivity, bone inductivity, biocompatibility, antibacterial property and easy functionalization. (francis-press.com)

Her thesis focused on characterization of bioactive glasses. (wikipedia.org)

Bioactive and biocompatible pieces of HA/sol-gel glass mixtures obtained by the gel-casting method: a new route for high quality, net-shape ceramics. (9pdf.info)
Biocompatible materials are used to repair or replace joints, fractured, or otherwise damaged bone. (iapchem.org)

Each year more than 500,000 arthritic or injured hips are replaced by orthopaedic surgeons around the world. (edu.au)

The bone morphogenetic protein (BMP-2) family of growth factors plays critical roles in bone formation. (springeropen.com)
Expression of particular growth factors such as vascular endothelial growth factor (VEGF) and bone morphogenetic proteins (BMPs) during the healing suggests a possible role for these secreted factors in bone repair. (springeropen.com)

However, this ability is lost when the area of the bone defect exceeds a critical size. (hindawi.com)
In clinical practice, autologous and allogenic bone grafts can be a "gold standard" in bone defect treatment, even they have certain limitations such as chronic pain, poor cosmesis, nonunion, and infection [ 2 , 3 ]. (hindawi.com)

These disadvantages can result in complications and the development of a bone substitute materials offers a potential alternative to overcome these shortcomings. (frontiersin.org)
Since WH has been shown to have positive effects on the enhancement of bone formation in a rat calvaria model, it may represent a potential bone substitute material to be used for the spinal fusion. (biomedcentral.com)

Where necessary, we subjected the bone-implant interface to a mechanical fracture test. (toysis.pics)

One such pathway, angiogenesis mediated by vascular endothelial growth factor (VEGF), is important for the coupling of cartilage resorption and mineralized bone formation during endochondral ossification in bone development (Huang et al. (springeropen.com)
These effects of VEGF lead to enhanced cartilage formation, accelerated resorption, and improved bone formation (Hu & Olsen, 2016 ). (springeropen.com)
This sequence mimics the events that occur at sites of natural bone remodeling where the surface left by resorption of active osteoclasts presents a nanotopographically complex surface with undercuts [3], [4]. (toysis.pics)

Abstract: Bone is a composite of a mineral (carbonatehydroxyapatite, CHA) and a polymer (collagen). (isbweb.org)

Bone-on-a-Chip: A Microscale 3D Biomimetic Model to Study Bone Regeneration. (merlninstitute.com)

10 https://en.wikipedia.org/wiki/Ceramic (accessed in March 2018). (ceramic-science.com)

The optimized UHMWPE eluted antibiotic at a higher concentration for longer than the clinical gold standard antibiotic-eluting bone cement, while retaining the mechanical and wear properties of clinically used UHMWPE joint prostheses. (nature.com)
Bone cement is regarded as a trustworthy anchoring material owing to its simplicity in clinical practice and, more specifically, given its shown high percentage of survival for prostheses that are cemented in. (emergenresearch.com)

In this review, we introduce the broad application of β-TCP in tissue engineering and discuss the different approaches that β-TCP scaffolds are customized, including physical modification (e.g., pore size, porosity and roughness) and the incorporation of metal ions, other materials (e.g., bioactive glass) and stem cells (e.g., mesenchymal stem cells). (frontiersin.org)
Over the last decades, mesenchymal stem cells (MSCs) have attracted extensive attention in the field of bone regeneration [ 4 - 7 ]. (hindawi.com)

Hip and Knee Arthroplasty: Annual Report 2015 (Australian Orthopaedic Association National Joint Replacement Registry, 2015). (nature.com)
On the basis of application, the bone cement & glue market has been segmented into arthroplasty, total knee arthroplasty, total hip arthroplasty, total shoulder arthroplasty, kyphoplasty, and vertebroplasty. (emergenresearch.com)

The results indicate an enlarged opportunity of magnesium-based materials for orthopedic applications, where friction and wear are involved, by applying PEO. (ua.pt)
The micro-CT result from the posterolateral fusion model showed whitlockite had slightly but significantly higher percent bone volume than tricalcium phosphate, though none of the materials formed successful fusion with surrounding bone tissue. (biomedcentral.com)
Bioactive Materials, 19, 127-138. (merlninstitute.com)
In vitro experimental study on bone promoting ability and mechanism of silicatitanium dioxide microporous coating materials for artificial joint prosthesis D, Suzhou: Soochow University, 2012. (francis-press.com)
The materials utilized to replace bone must have mechanical qualities comparable to those of bone. (iapchem.org)
The mechanical properties of the implant materials were most important and had a considerable impact on the process of bone restoration. (iapchem.org)

The attraction towards Ti and its alloys reside in their superior mechanical and tribological features, as compared to CaPs, which are renowned for their compositional and structural features similar to those of natural bones. (infim.ro)
Incorporation of carbon nanostructures significantly improves the mechanical properties of various biomaterials to mimic that of natural bone. (openorthopaedicsjournal.com)

In this project, several strategies based on bioactive glasses (BGs) [3] will be explored to functionalise PEEK surfaces. (fau.eu)
We have found that even the smoothest surfaces, when modified with submicron crystals, can bond to bone. (toysis.pics)
However, as the movement stress through the bone to the implant increased with healing time, such interfaces failed while others with submicron features superimposed on surfaces of increasing microtopographical complexity remained intact under stress. (toysis.pics)
9]. We therefore hypothesize that bone bonding could occur on surfaces with submicron topographical complexity in the absence of microtopography. (toysis.pics)

Lu has said that integrative tissue engineering will eventually "pave the way for total limb regeneration. (wikipedia.org)
The growing importance of regenerative medicine and tissue engineering (TE) reflects the fact that bone metabolic and related diseases represent approximately 50% of all chronic diseases for people above the age of fifty. (encyclopedia.pub)
A selective literature review was performed for carbon nanostructure composites in bone tissue engineering. (openorthopaedicsjournal.com)
In the quest for alternative therapeutic strategies, research is focusing on the concept of tissue engineering to assist the progress of bone tissue regeneration. (openorthopaedicsjournal.com)
Bone tissue engineering. (dokumen.pub)
Nanocomposites in bone tissue engineering applications. (dokumen.pub)
bone repair, bone substitution, bone augmentation, as scaffolds for tissue engineering for regeneration of teeth and bones, drug delivery, gene therapy and osteoporosis therapy. (isbweb.org)
S. Bose, S. Tarafder, Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review, Acta Biomaterialia 8 (2012) 1401-1421. (iapchem.org)

A new bone adhesive candidate- does it work in human bone? (uu.se)
Application of bone cement and adhesive frequently need specialized expertise and training in order to ensure optimal use and patient safety. (emergenresearch.com)
Need for bone cement and adhesive develops along with demand for arthroplasty procedures. (emergenresearch.com)

45S5 bioactive glass surface zeta potential variations in electrolyte solutions with and without fibronectin (PhD). University of Pennsylvania. (wikipedia.org)
The histology results showed the bone formed on the cortical surface of the transverse process but did not form a bridge between the processes. (biomedcentral.com)
Bony union means the interlocking of the cement matrix of the bone with the properties of the underlying implant surface. (toysis.pics)
When the bone is attached to the implant surface, the force that breaks the pattern causes the bone to detach from the bone-implant interface [5], [6]. (toysis.pics)
In fact, it is salutary to emphasize that in natural bone remodeling, the cementum matrix invades the underlying resorbed bone surface to a depth of about one micron, which corresponds to the depth of penetration of the fibrous rim of the ruffled membrane of osteoclasts in the resorbed matrix. (toysis.pics)
However, using the natural bone interface as a model, it is also evident that osteoclasts produce Howship lacunae, which are depressions excavated in the bone surface ranging in size from microns to hundreds of microns. (toysis.pics)
Furthermore, Howship's lacunae form themselves on a bone surface with an even higher order topography, as can be seen from the strut-like morphology of the bony trabeculae in cancellous bone. (toysis.pics)

In particular, her recent research has focused on rotator cuff repair, although potential applications extend to any soft tissue-bone interface repairs. (wikipedia.org)
Nanocomposites in orthopedic drug delivery applications. (dokumen.pub)
This is due to rising demand for bone cement in orthopedic applications. (emergenresearch.com)
Hence, rising demand for bone cement in orthopedic applications is driving revenue growth of the segment. (emergenresearch.com)

Now bioceramic scaffolds are designed to induce bone formation and vascularization. (ceramic-science.com)

16. Widyaputra S, Sitam S, Suherna I, Fitri AD, Rachman A. Comparison of bone regeneration in hADMSC versus hUCBMSC with hBMMSC as a reference: A literature review of potential bone regeneration. (rjstonline.com)
In the late 1960s, strong interest grew in studying various types of ceramics as potential bone grafts thanks to their suitable biomechanical properties. (ceramic-science.com)

The present gold standard in bone grafting is autologous bone taken from the iliac crest or ribs, however, this process is related to significant morbidity and postoperative pain owing to an added graft harvesting process. (industryarc.com)

The interpositional graft used was a FDBA Bone Block from Tata Bone Bank in Mumbai not autogenous bone or particulate graft material. (implantsutra.com)

A bioinformatics approach to study the role of calcium phosphate properties in bone regeneration. (merlninstitute.com)
Bone cement is sub-segmented into Polymethyl Methacrylate (PMMA) Cement, Calcium Phosphate Cement (CPC), Glass Polyalkenoate Cement (GPC), Antibiotic-loaded Bone Cement and Non-antibiotic-loaded Bone Cement. (emergenresearch.com)

Lu has studied biomaterials for regeneration of tendons and ligaments extensively, focusing on bioinspired approaches. (wikipedia.org)
Unfortunately, this has also caused a drastic increase in musculoskeletal conditions impacting bones, joints and tendons, which impose annual costs of $5.7 billion on the Australian healthcare system. (edu.au)

Besides, both in vitro and in vivo studies substantiated that ECH-MS/ROP stimulated myelinated axon regeneration through the MEK/ERK signaling pathway, thereby improving muscular denervation atrophy and facilitating functional recovery. (bvsalud.org)
In vitro testing of Mg-based orthopedic biomaterials. (dokumen.pub)

Anatomy34

Organisms11

Diseases16

Chemicals and Drugs49

Analytical, Diagnostic and Therapeutic Techniques and Equipment33

Phenomena and Processes26

Disciplines and Occupations1

Technology, Industry, Agriculture23

Implants22

Surgery8

Scaffolds for bone tissue3

Enhance bone regeneration2

Repair and regeneration4

Biodegradable1

Coatings3

Tissues7

Defects7

Hydroxyapatite7

20222

Trauma4

Osteogenic6

Cements1

Biomaterials for bone3

Stabilization2

Substitutes4

Molecules2

Osteoinductive2

Promote bone1

Biomaterial3

Fractures3

Nanoparticles1

Osteogenesis3

Scaffold4

Hydrogels1

Additive Manufacturing2

Biocompatibility2

Characterization1

Biocompatible2

Surgeons1

Morphogenetic2

Defect2

Substitute2

Fracture1

Resorption3

Abstract1

Biomimetic1

20181

Prostheses2

Mesenchymal stem2

Knee Arthroplasty2

Materials6

Mechanical2

Surfaces4

Tissue Engineering8

Adhesive3

Surface7

Applications4

Bioceramic1

Potential bone2

Autologous bone1

Autogenous bone1

Calcium2

Tendons2

Vitro2