• Relevant studies published by September 30, 2004, were identified through literature searches using EMBASE and MEDLINE and MeSH heading search strategy (using terms such as birth weight, intrauterine growth retardation, fetal growth retardation and cholesterol, lipoprotein, lipid). (nih.gov)
  • Anatomically modern humans (us), evolved about 200,000 years ago in Africa. (livescience.com)
  • This finding suggests that further analysis of these African groups "will help us understand the emergence of anatomically modern humans. (livescience.com)
  • Instead of pinpointing a single location from which modern humans arose, the genetic analysis revealed "different parts of Africa show up as potentially being the origin of anatomically modern humans," Jakobsson said. (livescience.com)
  • That suggests many different groups contributed to the gene pool "that then later on became anatomically modern humans," he explained. (livescience.com)
  • Taken together, we propose a southern African origin of anatomically modern humans with sustained homeland occupation before the first migrations of people that appear to have been driven by regional climate changes. (nature.com)
  • Researchers use an inducible gene to limit tumor growth from human iPSCs transplanted into mice. (the-scientist.com)
  • For the past 20 years, plenty of studies have suggested that only a small subpopulation of the cancer cells with tumor-initiating capability is the core origin of the tumorigenesis and the subset of cancer cells was named cancer stem cells (CSCs). (bmbreports.org)
  • Human tumor xenografts are vascularized and infiltrated by cells of mouse origin during the growth phase in vivo . (jove.com)
  • The overall goal of this procedure is to rapidly isolate xenotransplanted human tumor cells from mice to improve the downstream analysis of the desired target cells. (jove.com)
  • The elimination of the contuminating mouse cells by this method allows the specific assessment of human tumor cell gene expression or in vitro direct responses. (jove.com)
  • The main advantage of this technique is that the human tumor cells can be quickly and easily isolated without having to identify any surface markers on the target cells. (jove.com)
  • Then centrifuge the cells and resuspend the human tumor mouse stromal cell pellet in five milliliters of PB buffer. (jove.com)
  • To address this, we here established two autologous CAF lines representing inflammatory CAFs (iCAFs) and myofibroblast CAFs (myCAFs) and compared them with already established interlobular- and lobular fibroblasts with respect to their origin and impact on tumor formation. (lu.se)
  • Methods: Primary breast tumor-derived CAFs were transduced to express human telomerase reverse transcriptase (hTERT) and sorted into CD105 low and CD105 high populations using fluorescence-activated cell sorting (FACS). (lu.se)
  • We find that both property rights institutions and human capital are positively related to economic growth, although human capital is relatively more robust when we account for country fixed effects. (springer.com)
  • It was also a crisis of economic growth, for lord-princes were compelled by increased numbers of productive people to impose accountability on their appointed agents, to learn how to manage as well as to exploit. (rorotoko.com)
  • This research develops an evolutionary growth theory that captures the interplay between the evolution of mankind and economic growth since the emergence of the human species. (ssrn.com)
  • This unified theory encompasses the observed evolution of population, technology and income per capita in the long transition from an epoch of Malthusian stagnation to sustained economic growth. (ssrn.com)
  • The objective of this article is to study the direct and indirect effects of corruption control via the action of public power on economic development (economic growth, education, health, etc. (uni-muenchen.de)
  • Economic growth, control of corruption, action of public power, Human capital and Models of simultaneous equations. (uni-muenchen.de)
  • Institutions and economic growth: an historical introduction, Cornell" University on the role of Institutions in Economic Developpement, Ithaca, NewYork. (uni-muenchen.de)
  • and (iii) to explain the variations in the timing and pace to reaching sustained economic growth. (lu.se)
  • I've always thought that human evolutionary science has some compelling images, and we rarely see them in top science images lists, which often feature brightly colored micrographs. (johnhawks.net)
  • Also, dark-skinned people have been mistreated, and sometimes even killed, because racist evolutionists promulgated the doctrine that dark-skinned humans were evolutionary inferiors. (creationworldview.org)
  • Economists and social scientists have long debated the relative importance of institutions and human capital as fundamental determinants of long-run development. (springer.com)
  • We also investigate whether the growth effects of property rights institutions are heterogeneous across different levels of development. (springer.com)
  • This may aid researchers in the development of therapeutics for growth hormone defects and lead to a greater understanding of the causes of other genetic disorders. (sciencedaily.com)
  • Biologists also rejected preformationism, since studies of cytology and embryology clearly showed that development is much more than the simple growth of a preformed organism. (encyclopedia.com)
  • Meanwhile, morality serves as an important component of life, and the development of human life is inseparable from morality. (scirp.org)
  • In fact, morality comes from life whether in terms of its origin or motive force of development. (scirp.org)
  • It's caused by calcification of growth plates, which curtails long bone development and results in short legs with a curved appearance. (nih.gov)
  • This results in overproduction of the FGF4 protein, which the researchers hypothesize may turn on key growth receptors at the wrong times during fetal development. (nih.gov)
  • These appear linked with skeletal development, such as bone and cartilage growth, as well as immune system and brain cell function. (livescience.com)
  • The station will open the next chapter of human space exploration and development by facilitating the growth of a vibrant ecosystem and business model for the future,' the company had announced. (ahmedabadmirror.com)
  • The Colonial Origins of Comparative Development: An Empirical Investigation. (uni-muenchen.de)
  • The findings resulting from this analysis have implications for our understanding on the origins and consequences of the development process (output growth, human capital accumulation, fertility transition). (lu.se)
  • Effective intersectoral collaboration must be underpinned by the development, in each country, of a common multisectoral national plan for prevention of zoonosis in humans and animals. (who.int)
  • In N. J. Salkind (Ed.), Encyclopedia of Human Development (Vol. 3, pp. 1303-1307). (bvsalud.org)
  • What Is the Human Development Index (HDI)? (who.int)
  • The Human Development Index is a composite index that measures the development of a country based on three key dimensions. (who.int)
  • It was introduced by the United Nations Development Programme (UNDP) in 1990 as a more comprehensive measure of human development than traditional economic indicators such as gross domestic product (GDP) or income per capita. (who.int)
  • The HDI takes into account various indicators to assess the overall level of human development. (who.int)
  • The HDI (Index) is a summary measure of human development. (who.int)
  • It measures the average achievements in a country in three basic dimensions of human development: a long and healthy life, access to knowledge and a decent standard of living. (who.int)
  • For details on how index calculated, see latest UNDP Human Development Report, available from http://hdr.undp.org. (who.int)
  • The United Nations Development Programme (UNDP) developed an analytical tool known as the Human Development Index to measure and compare countries' levels of social and economic development. (who.int)
  • This composite index provides a multi-dimensional perspective of human development because it is not merely based on gross national income, but also on other significant aspects such as life expectancy at birth, educational achievement, and standard of living. (who.int)
  • The numerical HDI value ranges from zero to one: the higher the value, the higher the level of human development. (who.int)
  • A study of various countries by HDI map illustrates an evident disparity in human development levels globally. (who.int)
  • Thus, It is an indispensable tool for policymakers worldwide to gauge the progress of nations and to devise strategies designed to assist countries in enhancing their human development indices. (who.int)
  • 1. Growth and organ development / T.J. Cole -- 2. (who.int)
  • Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia. (lu.se)
  • Some developmental biologists study a whole organism for only a short period of its growth. (encyclopedia.com)
  • By studying these stages, developmental biologists gain insight into the origin of species, the relationships between them, and many of the diseases of growth or deterioration that can affect both animals and humans. (encyclopedia.com)
  • The origins of developmental biology lie in the search to understand the phenomenon of evolution. (encyclopedia.com)
  • Inverse associations between birth weight and subsequent blood cholesterol levels have been used to support the "fetal origins" hypothesis of the relevance of fetal nutrition to adult disease. (nih.gov)
  • These findings suggest that impaired fetal growth does not have effects on blood cholesterol levels that would have a material impact on vascular disease risk. (nih.gov)
  • Journal of Human Evolution , 180 , 103372. (johnhawks.net)
  • The theory suggests that prolonged economic stagnation prior to the transition to sustained growth stimulated natural selection that shaped the evolution of the human species, whereas the evolution of the human species was the origin of the take-off from an epoch of stagnation to sustained growth. (ssrn.com)
  • Origin and evolution of the earth system d. (polartrec.com)
  • Origin and evolution of the universe a. (polartrec.com)
  • Evolution of human lactation and complementary feeding: Implications for understanding contemporary cross-cultural variation / D.W. Sellen -- 19. (who.int)
  • There's one gene where if you have mutations in that gene, you get heavy eyebrow ridges and rib cages that look like something that could potentially be Neanderthal or archaic human ," Jakobsson told LiveScience. (livescience.com)
  • The human genome is comprised of both non-coding DNA and coding regions, or genes. (sciencedaily.com)
  • At the genomic level, a 14,000 base-pair separation is equal to the size of 10 growth hormone genes lined end to end. (sciencedaily.com)
  • Genome imprinting is an epigenetic marking mechanism that causes genes to be expressed in a parental-origin-specific manner. (bmj.com)
  • Much remains uncertain about how modern humans originated in Africa's cradle of humanity . (livescience.com)
  • That is well before modern humans migrated out of Africa and about twice as old as the divergences of central African Pygmies and East African hunter-gatherers and from other African groups, said researcher Carina Schlebusch at Uppsala University in Sweden. (livescience.com)
  • The researchers also identified genetic variations that emerged before this split between the Khoe-San and other groups, adaptations linked to the rise of modern humans as a whole. (livescience.com)
  • Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. (nature.com)
  • Across three different murine models of human prostate and breast cancer, KBU2046 inhibits metastasis, decreases bone destruction, and prolongs survival at nanomolar blood concentrations after oral administration. (nature.com)
  • Efficacy of KBU2046 is demonstrated across several different in vitro models and across multiple murine models of human cancer metastasis, which includes decreased metastasis, decreased bone destruction, and prolonged survival. (nature.com)
  • Growth factors may emerge as an interesting alternative in the reconstruction of tissues, highlighting the growth hormone (GH), a regulator of bone growth and remodeling, which plays a key role affecting chondrocytes, osteoclasts, and osteoblasts. (bvsalud.org)
  • Bone substitutes from different origins are extensively used in surgical practice. (bvsalud.org)
  • Osteogenic differentiation and bone formation assays in culture and in vivo were employed to gauge for origin in bone marrow-derived mesenchymal stem cells (bMSCs). (lu.se)
  • If this is found, you may need to discuss with your doctor whether or not an adjustment to your diet and lifestyle would be possible without losing too much weight, growth hormone deficiency. (jakesediting.com)
  • HGH injections are approved to treat adults and children who have growth hormone deficiency, for people who are undergoing organ transplants, and for AIDS-related muscle wasting. (jakesediting.com)
  • In the United States, recombinant human growth hormone is used in the pediatric population to treat short stature due to growth hormone deficiency (including idiopathic [of unknown cause] growth hormone deficiency), Turner syndrome, Noonan syndrome, Prader-Willi syndrome, short stature homeobox-containing gene (SHOX) deficiency, chronic renal insufficiency, idiopathic short stature and children small for gestational age. (fda.gov)
  • The risk of death was reported to be increased when doses of recombinant growth hormone that are higher than what is normally prescribed for pediatric growth hormone deficiency were used. (fda.gov)
  • The approved doses in the United States for pediatric growth hormone deficiency are below 50 mcg/kg/day, except during puberty, when a higher dose regimen is approved for a limited duration of time.For short stature indications other than growth hormone deficiency, doses up to 69 mcg/kg/day (0.48 mg/kg/week) are currently approved. (fda.gov)
  • The unexpected discovery provides clues about how physical differences may arise within species and suggests new approaches to understanding a form of human dwarfism. (nih.gov)
  • All human viruses have their origin in a virus that crossed from a different animal species. (virology.ws)
  • Stringer, C. & Galway-Witham, J. On the origin of our species. (nature.com)
  • Countless species of animals are sources of viral, bacterial and parasitic diseases transmitted to humans. (who.int)
  • If someone has abnormal levels of Growth Hormone or a growth hormone test is abnormal a diagnosis of pituitary androgen deficiency will be made, human growth hormone thailand. (noshamementalgains.com)
  • Impaired RNase MRP enzyme complex causes dwarfism, skeletal abnormalities, abnormal immune system function (immune deficiency), elevated cancer risk, sparse hair growth (hypotrichosis), and other signs and symptoms of cartilage-hair hypoplasia. (medlineplus.gov)
  • Acute experimental exposures of humans to lower concentrations of zinc oxide (14 mg/m3 for 8 hours or 45 mg zinc/m3 for 20 minutes) and occupational exposures to low concentrations of zinc (8-12 mg zinc/m3 for 1-3 hours and 0.034 mg zinc/m3 for 6-8 hours) did not produce symptoms of metal fume fever. (cdc.gov)
  • This reaction is also important in the human airways, where endogenous NH3 concentrations arc much higher than atmospheric levels. (cdc.gov)
  • The investigators found the earliest diversification event in the history of all humans occurred about 100,000 years ago. (livescience.com)
  • LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification. (lu.se)
  • Researchers have developed a technique to visualize the origin of melanoma in zebrafish, throwing light on a genetic switch for cancer. (the-scientist.com)
  • Researchers recently discovered a novel mechanism that works over an extensive genomic distance and controls the expression of human growth hormone (hGH) in the pituitary gland. (sciencedaily.com)
  • Researchers at the University of Pennsylvania School of Medicine recently discovered a novel mechanism that works over an extensive genomic distance and controls the expression of human growth hormone (hGH) in the pituitary gland. (sciencedaily.com)
  • While mutations to the hGH gene often lead to abnormal growth in children and adults, these mutations have provided researchers with key clues regarding the genomic areas that appear to control expression of the hGH gene. (sciencedaily.com)
  • To understand what causes chondrodysplasia, a team of researchers led by Dr. Elaine Ostrander of NIH's National Human Genome Research Institute (NHGRI) examined DNA samples from 835 dogs from 76 distinct breeds, including 95 dogs from 8 breeds with short legs. (nih.gov)
  • Researchers reported Sept. 20, 2012, in the journal Science, that the hunter-gatherers are an offshoot from the earliest split found yet in living humans. (livescience.com)
  • For instance, researchers had long thought humans arose in eastern Africa, but recent studies hint at roots in southern Africa. (livescience.com)
  • HGH injections should not be compared to injections for other treatments because there is no real difference in the severity of the symptoms, human growth hormone meaning. (jakesediting.com)
  • Food raw materials and products sold in the markets were in of uncertain origins and had no certificates of quality and hygiene. (who.int)
  • The dogs have an extra copy of the gene that codes for a growth-promoting protein called fibroblast growth factor 4 (FGF4). (nih.gov)
  • CD81 has a very broad cellular distribution, being expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin. (bdbiosciences.com)
  • On molecular analysis, SDC had high rates of androgen receptor (AR) (90%) and human epidermal growth factor receptor 2 (HER2) (55%) positivity. (ecancer.org)
  • They may also have implications for understanding human biology and disease. (nih.gov)
  • The New York Times recently published an article about population growth and the young age structure in sub-Saharan Africa. (populationconnection.org)
  • Let's explore what degrowth proponents aim to achieve and how this fits in with the goal of ending human population growth. (populationconnection.org)
  • The encounters that lead to these spillovers are driven by explosive human population growth and incredible change occurring in all ecosystems brought about by human occupation of almost every corner of the planet. (virology.ws)
  • The importance of zoonotic diseases has increased at global and regional levels in recent years in connection with human population growth, intensive human and wildlife migration, urbanization, increased international travel and trade of animals and products of animal origin, and intensification of animal production. (who.int)
  • Cutaneous tumors encompass a vast array of malignancies, ranging from neuroendocrine to lymphoid in origin. (medscape.com)
  • As with all tumors, whether benign or malignant, identification of the cell or cell layer of origin is of the utmost importance. (medscape.com)
  • The origin of cutaneous tumors can be simplistically divided into three major categories: epidermal, dermal, and adnexal (see image below). (medscape.com)
  • In addition, the growth of v-src DNA tumors and antibody response against sheep red blood cells differed among the 2 parental lines and the RCS. (bvsalud.org)
  • As with all tumors, whether benign or malignant, the paradigm of comprehension depends on identifying the cell or cell layer of origin. (medscape.com)
  • To help uncover the origins of humanity, scientists analyzed genetic variations across 220 individuals from 11 different populations in southern Africa to explore their relationships and commonalities. (livescience.com)
  • Analytes include soluble growth and differentiation factors, extracellular matrix components, proteases, membrane-bound receptors, and intracellular signaling molecules. (rndsystems.com)
  • According to one 2021 laboratory study, red algae contains a sugar called 3,6-anhydro-L-galactose, or AHG, which inhibits the growth of human colon cancer cells without affecting the growth of normal cells. (drweil.com)
  • Genetic analysis and epidemio- at 1:10 dilution on FRhK-4 cells infected with either a logic studies suggest that SARS coronavirus (CoV) was human SARS-CoV strain (GZ50) (5) or an animal SARS- introduced into humans not long ago. (cdc.gov)
  • The Khoe-San people of southern Africa, who speak a language based on clicking sounds, are descendants of the most ancient genetic split found yet in living humans, finds an international group of scientists. (livescience.com)
  • Most of the cancers are still incurable human diseases. (bmbreports.org)
  • In addition to causing human morbidity and mortality, such diseases hamper agricultural production, decrease availability of food and create barriers to international trade. (who.int)
  • Many of the human diseases that are new, emerging and re-emerging are caused by pathogens which originate in animals or products of animal origin. (who.int)
  • Seventeen (1.8%) archived samples from healthy adults investigations raised questions about whether the presence showed IF antibodies against the human virus, animal of the animal SARS-CoV-like virus in the market was an virus, or both (titer range 1:20 to 1:1,280) and were con- isolated event or if this virus had been prevalent in the firmed by serum neutralization assay. (cdc.gov)
  • A retrospective serologic study was conducted to either animal or human viruses, but they were negative in address these questions. (cdc.gov)
  • It is required in order for cells to invade through the basement membrane, represents an initial step in the metastatic cascade, and is necessary for cells to move from their primary organ of origin to distant metastatic sites. (nature.com)
  • In addition to serving as a major contributor to height growth during childhood, hGH plays a role in strengthening bones and increasing muscle mass throughout life. (sciencedaily.com)
  • 1-3 It was designed to assess the long-term mortality of patients treated with recombinant human growth hormone during childhood. (fda.gov)
  • The study population was based on a mandatory registry of patients in France who received recombinant human growth hormone treatment during childhood between 1985 and 1996 and whose vital status and cause of death was determined through September 2009. (fda.gov)
  • FDA is aware of the results of a long-term epidemiological study called SAGhE (SantĂ© Adulte GH Enfant), which was designed to assess the long-term mortality of patients treated with recombinant human growth hormone during childhood. (fda.gov)
  • 1-3 This study was based on a mandatory registry of patients in France treated with recombinant growth hormone during childhood between 1985 and 1996. (fda.gov)
  • The bio-safety committee is restrained from issuing any GM organism licenses and the government has been directed to establish a new regulatory regime for the implementation of the Cartagena Protocol,' an international agreement which aims to ensure the safe handling, transport and use of living modified organisms (LMOs) resulting from modern biotechnology that may have adverse effects on biological diversity, taking also into account risks to human health. (whale.to)
  • The dawn of human matrilineal diversity. (nature.com)
  • Ingredientes alimentarios no digeribles, principalmente en forma de CARBOHIDRATOS, que mejoran la salud humana estimulando selectivamente el crecimiento o la actividad de las BACTERIAS que existen en el COLON. (bvsalud.org)
  • Non-digestible food ingredients mostly of a carbohydrate base that improve human health by selectively stimulating the growth and/or activity of existing BACTERIA in the COLON. (bvsalud.org)
  • An additional six human population in southern China before the SARS out- samples were IF-antibody positive at a 1:10 dilution to break. (cdc.gov)
  • had a higher IF or neutralization antibody titer to the ani- and Pamela Youde Nethersole Eastern Hospital, Hospital mal virus than the human virus (Figure). (cdc.gov)
  • Multiparameter flow cytometric analysis using BD OptiBuild™ BV786 Mouse Anti-Human CD81 (TAPA-1) antibody (Cat. (bdbiosciences.com)
  • Age 2.6 Sex XY Ethnic origin China Parents Non-consanguineous Comment Patient's mother had hyperthyroidism. (lu.se)
  • The origins of Agent Orange lie in an obscure laboratory at the University of Chicago where, during World War II, the chairman of the school's biology department, E. J. Kraus, discovered that direct doses of 2,4-D can kill certain broadleaf vegetation by causing the plants to experience sudden, uncontrolled growth not unlike that of cancer cells in the human body. (dissidentvoice.org)
  • Why would a person with hypothyroidism develop growth hormone test abnormalities that make their thyroid gland very weak? (noshamementalgains.com)
  • Hypothyroidism, or the failure of the thyroid to produce enough thyroid hormone, can lead to a number of conditions, including low iron levels in the blood, a drop in red blood cell counts and anemia (low red blood cells), low sperm count and an increased incidence of blood clots and other blood problems, human growth hormone sale. (noshamementalgains.com)
  • If you have an abnormally low or decreased testosterone and/or Estradiol levels then you may have low thyroid function and be thought to need an adjustment to your diet and lifestyle to compensate, human growth hormone sale. (noshamementalgains.com)
  • If you have an underactive thyroid, or are having a growth hormone test that is abnormally low in your blood and are concerned then it is important that you have a thorough consultation with your doctor, human growth hormone over 40. (noshamementalgains.com)
  • You should probably avoid Winstrol if you have thyroid disease, or if you regularly use other prescription steroids, like Anavar, prednisone, prednisolone, prednisolone/rindole, dexamethasone and other steroids containing the dianabol steroid compound (e, growth hormone function.g, growth hormone function. (noshamementalgains.com)
  • Among other things, we ask if you have ever been treated with growth hormone and thyroid stimulating hormones of human origin. (sanquin.nl)
  • Insights into the behavioral capabilities of ancient human relatives are beginning to show that some of the abilities we consider human go surprisingly deep in our ancestry. (johnhawks.net)
  • If you prescribe recombinant human growth hormone, follow the recommended indications and doses in the product labels. (fda.gov)
  • In addition, we note that the rate of conditional convergence to the steady state, measured by the coefficient on ln Y , increases when important determinants of the steady state (e.g. human capital, institutions) are included in the regression (as noted by Knack and Keefer 1995 ). (springer.com)
  • The study fed these rats NK603 , the Monsanto variety of GM corn that's grown across North America and widely fed to animals and humans. (whale.to)
  • Raising awareness among decision- makers and policy-makers on the burden of zoonoses in humans and animals will assist in securing political commitment and financial support for zoonosis control programmes. (who.int)
  • Zinc is an essential nutrient for humans and animals that is necessary for the function of a large number of metalloenzymes, including alcohol dehydrogenase, alkaline phosphatase, carbonic anhydrase, leucine aminopeptidase, and superoxide dismutase. (cdc.gov)
  • Recombinant human growth hormone is a protein that is manufactured to be nearly identical to the main form of the naturally occurring human growth hormone. (fda.gov)
  • In recent years, some manufacturers, including the Origins brand, have begun including red algae in skincare products. (drweil.com)
  • Some study the cell growth, or how specialized cell types differentiate from stem cells. (encyclopedia.com)
  • We identify a unique cell motility regulatory mechanism and synthesize a targeted therapeutic, providing a platform to pursue studies in humans. (nature.com)
  • It is involved in cell growth and signal transduction. (bdbiosciences.com)
  • It also acts as a growth factor, locally produced and secreted by several cell types. (bvsalud.org)
  • It became a common practice to violate the technological, hygienic and sanitary procedures and regulations at packaging, preserving, transporting and selling meat, milk, potatoes and vegetables for human consumption. (who.int)
  • International Society for Research in Human Milk and Lactation. (who.int)
  • Measuring trace immune factors in human milk: workshop summary / S. Filteau -- 25. (who.int)
  • Proceedings of the 12th Symposium of the International Society for Research in Human Milk and Lactation 2004 held at Queens College, Cambridge. (who.int)
  • At this time, FDA believes the benefits of recombinant growth hormone continue to outweigh its potential risks. (fda.gov)
  • For people who have a chronic illness, HGH can help maintain metabolic control, human growth hormone supplements ingredients. (jakesediting.com)
  • and to trace their cellular origin. (lu.se)