• salivary
  • The glands that make saliva are called salivary glands. (webmd.com)
  • Saliva moves through tubes called salivary ducts. (webmd.com)
  • In addition to being important in speech and swallowing, saliva is also a vital part of the human defence system, containing secretory IgA and components such as lyzosyme, lactoferrin, histatins along with salivary peroxidase systems. (dentistry.co.uk)
  • The salivary antioxidant system has an essential anti-carcinogenic role in the oral cavity and plays a pivotal role in the pathogenesis of oral squamous cell carcinoma (OSCC) (Reznick, Hershkovich and Nagler, 2004). (dentistry.co.uk)
  • In the oral cavity salivary nitrates are converted to nitrites which then react with amines to form carcinogenic nitrosamines (Xia, Deng and Wang, 2003) (Deng, 2000). (dentistry.co.uk)
  • In addition to antioxidants, saliva also contains nitrosamine inhibitory agents along with another crucial anti-cancer salivary enzyme glutathione S-transferase (Stich, Rosin and Bryson, 1982). (dentistry.co.uk)
  • More recently Hershkovich, Shafat and Nagler (2007) looked at the increased prevalence of oral cancer among older people and suggested this may be due to an age related reduction in protective salivary antioxidant mechanisms and age related magnitude of oxidative stress from ROS and RNS exposure. (dentistry.co.uk)
  • In a healthy mouth, saliva is produced continuously by the salivary glands, which are located under our tongues and in our cheeks. (orthospecialistpc.com)
  • Salivary dysfunction has been reported to be a frequent oral complication in type 2. (ebscohost.com)
  • Saliva is a watery substance formed in the mouths of animals, secreted by the salivary glands. (wikipedia.org)
  • citation needed] Produced in salivary glands, human saliva is 99.5% water, but also contains many important substances, including electrolytes, mucus, antibacterial compounds and various enzymes. (wikipedia.org)
  • Without normal salivary function the frequency of dental caries, gum disease (gingivitis and periodontitis), and other oral problems increases significantly. (wikipedia.org)
  • The salivary glands in mammals are exocrine glands, glands with ducts, that produce saliva, which is composed of several components including amylase, a digestive enzyme that breaks down starch into maltose and glucose. (wikipedia.org)
  • The largest of the salivary glands, they secrete saliva to facilitate mastication and swallowing, and amylase to begin the digestion of starches. (wikipedia.org)
  • They produce 20% of the total salivary content in the oral cavity. (wikipedia.org)
  • Direct sympathetic innervation of the salivary glands takes place via preganglionic nerves in the thoracic segments T1-T3 which synapse in the superior cervical ganglion with postganglionic neurons that release norepinephrine, which is then received by β-adrenergic receptors on the acinar and ductal cells of the salivary glands, leading to an increase in cyclic adenosine monophosphate (cAMP) levels and the corresponding increase of saliva secretion. (wikipedia.org)
  • squamous cell carc
  • As published in the current issue of Clinical Cancer Research, the scientists found they could measure for elevated levels of four distinct cancer-associated molecules in saliva and distinguish with 91 percent accuracy between healthy people and those diagnosed with oral squamous cell carcinoma. (innovations-report.com)
  • a scientist at the University of California at Los Angeles (UCLA) School of Dentistry and senior author on the paper, it may be possible with further refinement of the test, possibly by including additional cancer-linked mRNAs, to attain the necessary 99 to 100 percent accuracy of commercial diagnostic tests for oral squamous cell carcinoma, the sixth most common cancer in the United States. (innovations-report.com)
  • We obtained saliva and blood from 32 people who had been recently diagnosed with oral squamous cell carcinoma but not treated," said Yang Li, D.D.S., Ph.D., lead author on the study and a researcher in Wong s laboratory. (innovations-report.com)
  • secretion
  • Bubble nests, also called foam nests, are created by some fish and frog species as floating masses of bubbles blown with an oral secretion, saliva bubbles, and occasionally aquatic plants, or an area for egg deposit attached at the bottom. (wikipedia.org)
  • mucus
  • Human saliva comprises 98% water, plus electrolytes, mucus, white blood cells, epithelial cells (from which DNA can be extracted), glycoproteins, enzymes (such as amylase and lipase), antimicrobial agents such as secretory IgA and lysozyme. (wikipedia.org)
  • specimen
  • Drugs that may be present in the oral fluid specimen compete against their respective drug conjugate for binding sites in their specific antibody. (ultimed.org)
  • During testing, a portion of the oral fluid specimen migrates upward by capillary action. (ultimed.org)
  • A drug, if present in the oral fluid specimen below its cut-off concentration, will not saturate the binding sites of its specific antibody. (ultimed.org)
  • The presence of drug above the cut-off concentration in the oral fluid specimen will saturate all the binding sites of the antibody. (ultimed.org)
  • A drug-positive oral fluid specimen will not generate a colored line in the specific test line region of the strip because of drug competition, while a drug-negative oral fluid specimen will generate a line in the test line region because of the absence of drug competition. (ultimed.org)
  • This means that there has been insufficient specimen volume or the instructions have not been followed correctly e.g. laying the oral cube on its side or upside down - these are the most likely reasons for the control line failing to appear. (homehealth-uk.com)
  • The Oral Cube test kit will then do the work getting the saliva oral specimen from the swab to the detection chamber and results will follow. (transmedco.com)
  • enzyme
  • Saliva also contains a catalytic enzyme called amylase which starts to act on food in the mouth. (wikipedia.org)
  • Saliva contains the enzyme amylase, also called ptyalin, which is capable of breaking down starch into simpler sugars such as maltose and dextrin that can be further broken down in the small intestine. (wikipedia.org)
  • Lactoperoxidase catalyzes the hydrogen peroxide (H2O2) oxidation of several acceptor molecules: reduced acceptor + H2O2 → oxidized acceptor + H2O Specific examples include: thiocyanate (SCN−) → hypothiocyanite (OSCN−) bromide (Br−) → hypobromite (BrO−) iodide (I−) → hypoiodite (IO−) Source of the hydrogen peroxide (H2O2) usually is the reaction of glucose with oxygen in the presence of the enzyme glucose oxidase (EC 1.1.3.4) that also takes place in saliva. (wikipedia.org)
  • Glucose, in turn, can be formed from starch in the presence of the saliva enzyme amyloglucosidase (EC 3.2.1.3). (wikipedia.org)
  • teeth
  • But saliva also contains important substances that your body needs to digest food and keep your teeth strong. (webmd.com)
  • That's because saliva helps clear food particles from your teeth. (webmd.com)
  • Firstly, the enamel's outer film, the pellicle as it is called, is formed from saliva and puts a protective coating over the teeth. (curaprox.com)
  • Thirdly, saliva provides the teeth with important minerals. (curaprox.com)
  • There are many reasons we have saliva, but the most important role it plays for your teeth is keeping your mouth's pH balanced and flushing away remnants of food to keep everything clean. (orthospecialistpc.com)
  • In general, the more effective one's brushing, flossing, and other oral homecare practices, the less plaque will accumulate on the teeth. (wikipedia.org)
  • diagnostic
  • Wong noted that currently no biochemical or genetic diagnostic tests are commercially available for oral cancer. (innovations-report.com)
  • We re now conducting our initial studies of saliva as a possible diagnostic fluid for other human cancers and system diseases, and we should have our preliminary data in the Spring. (innovations-report.com)
  • The researchers claim that they were able to use 3 of the six species as a diagnostic tool to predict more than 80 percent of oral cancer cases. (medindia.net)
  • Saliva can also be used as a diagnostic tool as well as marker for monitoring diabetes mellitus. (ebscohost.com)
  • When collecting saliva for routine diagnostic purposes a number of basic problems should be prevented: analytes should not be unspecifically absorbed in or on the collection device, analyte stability should be assured and the sample volume should be known. (mdpi.com)
  • significantly
  • As presented in their current Clinical Cancer Research paper, the scientists extracted the mRNA from the saliva of the cancer patients and soon discovered 1,679 genes were expressed at significantly different levels in the cancer patients compared to healthy individuals. (innovations-report.com)
  • substances
  • This is a contact sensitivity (type IV hypersensitivity reaction) in the oral tissues to common substances such as sodium lauryl sulfate, cinnamaldehyde or dental materials. (wikipedia.org)
  • ulceration
  • The antioxidant capacity of saliva appears to protect against oral cancers (Wu, Chi and Liu, 2005), and has been implicated in the progression of periodontal disease (Sculley and Langley-Evans 2003), susceptibility to periodontal disease and systemic inflammation associated with diabetes (Pendyala, Thomas and Joshi, 2013) and recurrent aphthous ulceration (Saral et al, 2005). (dentistry.co.uk)
  • test
  • The ulti med SalivaScreen Oral-Fluid Saliva Cup S2 is a test to monitor therapeutic measures. (ultimed.org)
  • With these baseline data as their scientific anchor, the researchers could begin to test whether saliva contains distinct mRNA patterns. (innovations-report.com)
  • The 3 in 1 Saliva Drug Test will test for the 3 most commonly abused medications and street drugs in the UK. (homehealth-uk.com)
  • Not only is this the easiest and most accurate drug test to use, it is also, as best we know, the only oral drug test that is specifically produced for the UK market and covers the 3 main street drugs found in the UK. (homehealth-uk.com)
  • Why is this oral test so good? (homehealth-uk.com)
  • I am just curious, if hiv is not transmitted from kissing without bloody contacts, why is it that oraquick, a product from orasure detects hiv presence in the saliva (no blood in saliva) during the 15 min test? (thebody.com)
  • Having said that, I will also point out that the OraQuick oral test is not a saliva-based test! (thebody.com)
  • new saliva test? (thebody.com)
  • If that's so, then why is there a new home test that may be approved and you take a swab from your mouth of saliva? (thebody.com)
  • Actually "saliva test" is somewhat of a misnomer. (thebody.com)
  • Any ways I took the Oraquick saliva test at 3,4,5 & 6 weeks. (thebody.com)
  • I am quite confused though as the girl at the clinic said to me at my 6 week test it takes the virus longer to show up in the saliva than in the blood.She acted like I was wasting my time but yet still took my money for a test even when I told her how many weeks it had been. (thebody.com)
  • The same three-month "window period" applies to this oral fluid test as to blood tests. (thebody.com)
  • Oral Cube makes it easy, the swab slides in and out of the test kit: out for application and back in for test results. (transmedco.com)
  • Oral fluids drug tests don't require privacy and are fully supervised, so it makes it practically impossible to tamper with the test. (arcpointlabs.com)
  • And because oral fluids are not considered a bio-hazard, disposal after the test is simpler too. (arcpointlabs.com)
  • Our permanent cleansing products will also prepare you for any saliva drug test in 1 - 8 days depending on your usage. (abdetox.com)
  • Contrary to current popular drug tests that require the individual to donate urine, the saliva swab drug screen test is an oral fluids drug test and is a top of the line product. (ipassedmydrugtest.com)
  • mouth
  • If dry mouth persists, your doctor or dentist may recommend rinsing your mouth with artificial saliva. (webmd.com)
  • Artificial saliva helps keep your mouth moist and comfortable. (webmd.com)
  • Pop something spicy or very sour in your mouth and your taste buds react by telling your body to make more saliva. (webmd.com)
  • How does saliva keep your mouth healthy? (curaprox.com)
  • Growth factors in saliva are why injuries in your mouth (like a burned tongue or a bitten cheek) heal faster than injuries elsewhere on the body. (orthospecialistpc.com)
  • Leukoplakia refers to a painless, raised white patch in the mouth that does not go away on rubbing, and is associated with an increased risk of getting oral cancer. (medindia.net)
  • Oral cancer is a cancer that develops in any part of the mouth. (medindia.net)
  • Dry mouth has multiple oral health consequences and affects quality of life. (ebscohost.com)
  • Dry mouth is something most oral cancer patients who underwent radiation treatments will struggle with for many years. (oralcancersupport.org)
  • She has suffered with over-production of saliva and a sour taste in her mouth ever since she was about 6 months post rads. (oralcancersupport.org)
  • The person holds it in their mouth for 2 to 5 minutes until it is saturated with saliva. (arcpointlabs.com)
  • Designed to be used alone or in conjunction with our Spit 'n Kleen oral mouth wash. (abdetox.com)
  • Oral candidiasis, also known as oral thrush among other names, is candidiasis that occurs in the mouth. (wikipedia.org)
  • That is, oral candidiasis is a mycosis (yeast/fungal infection) of Candida species on the mucous membranes of the mouth. (wikipedia.org)
  • A more recently proposed classification of oral candidiasis distinguishes primary oral candidiasis, where the condition is confined to the mouth and perioral tissues, and secondary oral candidiasis, where there is involvement of other parts of the body in addition to the mouth. (wikipedia.org)
  • periodontal
  • Oral health maintenance and periodontal interventions may reduce risks of diabetes, and cardiovascular and pulmonary disease. (ebscohost.com)
  • It is the first step in the decline of periodontal health, and the only step which can be fully reversed to restore one's oral health. (wikipedia.org)
  • proteins
  • While looking for cancer-linked proteins in saliva, St. John happened to notice mRNA from the gene encoding one of her proteins of interest. (innovations-report.com)
  • Saliva does all this with only 0.6% of its contents, added to which are proteins, minerals and enzymes. (curaprox.com)
  • Candida
  • This candidal carriage state is not considered a disease, but when Candida species become pathogenic and invade host tissues, oral candidiasis can occur. (wikipedia.org)
  • healthy
  • Saliva is an important part of a healthy body. (webmd.com)
  • If correct, are there different collective patterns of mRNA in the saliva of a healthy person compared with someone who has a developing cancer? (innovations-report.com)
  • SALIVA IS SUCH an ordinary thing that you probably haven't given it much thought, but it's actually as important to the healthy function of our mouths as oil is to a working car engine. (orthospecialistpc.com)
  • Saliva is an essential component of our ability to eat, taste our favorite foods, and speak, it's crucial to a healthy immune system, and it's our first line of defense against many oral health problems. (orthospecialistpc.com)
  • indicate
  • This so-called "proof-of-principle" study marks the first report in the scientific literature that distinct patterns of "messenger RNA" not only are measurable in saliva but can indicate a developing tumor. (innovations-report.com)
  • important
  • The global human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) pandemic has been an important factor in the move away from the traditional classification since it has led to the formation of a new group of patients who present with atypical forms of oral candidiasis. (wikipedia.org)
  • Products
  • In the past saliva drug testing products have been hard to use and confusing. (transmedco.com)
  • If you have extremely high toxin levels or just want to be sure, our saliva cleansing products can be combined to create the longest lasting, most effective solution available. (abdetox.com)
  • Rapid oral fluid products are not approved for use in workplace drug testing programs and are not FDA cleared. (wikipedia.org)
  • contains
  • Saliva contains a wide range of antioxidants including uric acid, albumin, vitamins A, C and E along with antioxidant enzymes such as reduced glutathione, oxidised glutathione, superoxide dismutase (SOD) and catalase (Nagler et al, 2002). (dentistry.co.uk)