• superficial
  • Clinical signs start with a superficial vascularization of the perilimbal corneal, and as the disease progresses, the lesions appear as an edematous area, an irregular and vascularized mass with pink to white infiltrates that form gritty yellow-white corneal plaques extending axially from the limbus. (springer.com)
  • lesions
  • Other, albeit less frequent, potential causes of the disease are: intracranial space-occupying lesions such as neuroma, meningioma and aneurysms, which may compress the trigeminal nerve and reduce corneal sensitivity. (wikipedia.org)
  • Descemet's
  • With descemetoceles, Descemet's membrane will bulge forward and after staining will appear as a dark circle with a green boundary, because it does not absorb the stain. (wikipedia.org)
  • severe
  • Results suggest that three separate DE models, with mild, moderate, and severe manifestations of DE, could be stably established, in which conjunctival goblet cells took an important role. (biomedcentral.com)
  • wound
  • ARVO E-Abstract 262) In a model of corneal wound healing, the CMHA film was found capable of delivering recombinant human growth hormone in a controlled, sustained manner both in vitro and in vivo over a course of days to months. (oraclinical.com)
  • surgical
  • The present invention also relates to a method for improving post surgery visual acuity outcome in a patient, comprising the steps of: identifying a patient in need of an ophthalmic surgical procedure, administering to the patient an effective amount of azithromycin prior to the ophthalmic surgical procedure, and performing the ophthalmic surgical procedures on the patient. (patentsencyclopedia.com)
  • 2. The method according to claim 1, wherein said patient in need of the ophthalmic surgical procedure has dry eye disease or is at the risk of developing dry eye disease. (patentsencyclopedia.com)
  • 4. The method according to claim 1, wherein said ophthalmic surgical procedure is cataract surgery. (patentsencyclopedia.com)
  • treatment
  • The paper also discusses different colloidal drug delivery systems and current challenges in the development of topical ophthalmic drug delivery systems for treatment of KCS. (hindawi.com)
  • method
  • 1. A method of treating dry eye syndrome comprising the step of administering a therapeutically effective amount of insulin to an afflicted eye conjunctival sac. (patentsencyclopedia.com)
  • 15. The method of treating dry eye syndrome according to claim 2 wherein said therapeutic agent comprising of Diquafosol (INS365 Ophthalmic) and Rebamipide. (patentsencyclopedia.com)