Ondansetron receptor antiemetics. Medical search. Frequent questions

Selective 5-HT 3 receptor antagonist. (empr.com)
Ondansetron is a selective 5-HT3 receptor antagonist. (empr.com)
Selective 5-HT3 receptor antagonist that blocks serotonin both peripherally and centrally. (medscape.com)
Several dopamine antagonist antiemetics commonly used in pregnancy also act as weak serotonin receptor antagonists. (biomedcentral.com)
Additionally, the 5-HT 3 receptor antagonist ondansetron is an often used antiemetic in pregnancy. (biomedcentral.com)
Our results will provide information regarding the utility of different strategies that can be used to mitigate cardiac risk amongst patients taking serotonin antagonist receptors. (biomedcentral.com)
Granisetron Kabi is a 5-HT3 receptor antagonist (serotonin antagonist), used in the prevention or treatment of chemotherapy and radiation therapy associated nausea and vomiting. (fresenius-kabi.com)
muscarinic acetylcholine receptors antagonist in parasympathetic nervous system. (ahlico.com)
Anti-psychotic (Dopamine receptors Antagonist). (ahlico.com)
Gastric acid secretion inhibitor (H2 receptor antagonist). (ahlico.com)
Dopamine receptors antagonist). (ahlico.com)
In France, Spain, and Italy, the dopamine receptor antagonist domperidone was preferred as antiemetic treatment. (ox.ac.uk)
Ondansetron is a 5-HT3 receptor antagonist, prescribed for nausea and vomiting caused by cancer chemotherapy, radiation therapy and surgery. (mtatva.com)
A competitive serotonin type 3 receptor antagonist. (pharmfair.com)
Ondansetron is a selective serotonin 5-HT 3 receptor antagonist. (pharmfair.com)
Animal and human studies show that Aprepitant augments the antiemetic activity of the 5-HT 3 -receptor antagonist ondansetron and the corticosteroid ethasone and inhibits both the acute and delayed phases of cisplatin induced emesis. (lgmpharma.com)
In summary, the active form of fosaprepitant is as an NK1 antagonist which is because it blocks signals given off by NK1 receptors. (lgmpharma.com)
Once biologically activated, the drug acts as a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy. (lgmpharma.com)
Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. (lgmpharma.com)
Cisplatin-based highly emetogenic chemotherapy (HEC) regimens, which are key treatments for some of malignant tumors, were conventionally administered after an antiemetic premedication with dexamethasone plus a 5-hydroxytryptamine 3 receptor antagonist (5-HT 3 RA) such as ondansetron or granisetron. (medscape.com)
Aprepitant, a neurokinin-1 (NK-1) receptor antagonist, and palonosetron, a second-generation 5-HT 3 RA, are two recently introduced antiemetic agents expected to improve control of CINV. (medscape.com)
Emeset 4 contains ondansetron, a potent 5HT3 receptor-antagonist that is used as an antiemetic to control nausea and vomiting following cancer chemotherapy and radiotherapy, also to prevent post-operative nausea and vomiting. (inhousepharmacy.vu)
The first 5-HT3, or serotonin receptor antagonist to be approved for use by the FDA was ondansetron. (nicerx.com)
Currently, Aloxi (palonosetron) is the only second-generation 5-HT receptor antagonist available. (nicerx.com)

Reported with 5-HT 3 receptor antagonists alone but particularly with concomitant use of serotonergic drugs. (nih.gov)
If these agents are unsuccessful, 5-HT3 receptor antagonists may be administered to control nausea and vomiting. (medscape.com)
The newer antiemetics used for the prevention and treatment of PONV are 5HT 3 receptor antagonists (ondansetron, granisetron, tropisetron, dolasetron) are devoid of these side effects. (ispub.com)
The use of these 5-HT 3 receptor antagonists have been shown to improve patients' satisfaction, decrease recovery and discharge times and reduced an unanticipated hospital admission especially when they are used prophylactically 25 26 .This prospective, randomized, double blind placebo controlled study was undertaken to compare the efficacy of granisetron and ondansetron in prevention PONV in patients undergoing gynecological laparoscopic surgeries. (ispub.com)
To increase their quality of life and treatment satisfaction, antiemetic medication, such as serotonin receptor antagonists, is often prescribed for patients experiencing these symptoms. (biomedcentral.com)
However, early warning signs suggest that serotonin receptor antagonists can cause harm, including arrhythmia. (biomedcentral.com)
Our objective is to identify the most effective interventions that mitigate the risk of adverse cardiac events associated with serotonin receptor antagonists in patients undergoing surgery and chemotherapy through a systematic review and network meta-analysis. (biomedcentral.com)
We will search electronic databases (for example, MEDLINE, Embase) from inception onwards, as well as dissertations and governmental reports, to identify interventions (for example, telemetry, electrocardiography, electrolyte monitoring) that decrease the cardiac risk associated with serotonin receptor antagonists among surgery and chemotherapy patients. (biomedcentral.com)
To prevent these symptoms, many patients are prescribed serotonin (5-HT3) receptor antagonists. (biomedcentral.com)
Serotonin receptor antagonists are powerful antiemetic medications that inhibit nerves in the gastrointestinal tract, blocking the emetic reflex [ 5 ]. (biomedcentral.com)
Serotonin receptor antagonists are recommended for patients suffering cyclic vomiting syndrome. (alcoholaddictioncenter.org)
Whereas serotonin antagonists , for example, bind 5-HT 3 receptors and effectively combat cytotoxic drug nausea , certain anticholinergic drugs target M 1 receptors and specifically treat motion sickness (kinetosis). (amboss.com)
There has been no phase III study of comparing the efficacy of first- and second-generation 5-HT 3 receptor antagonists in the triplet regimen with dexamethasone and aprepitant for preventing chemotherapy-induced nausea and vomiting after highly emetogenic chemotherapy (HEC). (medscape.com)
Examples of antiemetics include phenothiazines such as prochlorperazine (Compazine), antihistamines such as diphenhydramine (Benadryl) and meclizine (Antivert, Bonine), trimethobenzamide (Benzacot, Tigan, Ticon), cannabinoids, phosphorated carbohydrate solution (Emetrol), and 5-hydroxytryptamine-3 (5-HT3, serotonin) receptor antagonists such as ondansetron (Zofran). (gethomeworkdone.com)
These new selective 5-HT3 receptor antagonists marked a significant improvement in the treatment of nausea and vomiting. (nicerx.com)
5-HT3 receptor antagonists are a class of prescription drugs best known as antiemetics used for the treatment or prevention of nausea and vomiting due to chemotherapy, radiation therapy, or surgery. (nicerx.com)
First-generation 5-HT3 receptor antagonists examples include Zofran (ondansetron) and Sancuso (granisetron). (nicerx.com)

May relieve nausea and vomiting by blocking postsynaptic mesolimbic dopamine receptors through anticholinergic effects and depressing reticular activating system. (medscape.com)
Introduction: The aim of the study was to compare the antiemetic effects of intravenous ondansetron 80 mcg/kg and granisetron 40 mcg/kg in a double blind placebo controlled manner for prevention of postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgeries. (ispub.com)
Results: The incidence of nausea and vomiting over a period of 24 hour were found in 20% of patients who had received granisetron, 45% of patients who had received ondansetron and 77.5% of patients who had received placebo. (ispub.com)
Conclusion: It was concluded that granisetron is more effective than ondansetron and placebo in controlling postoperative nausea & vomiting after laparoscopic gynecological surgery. (ispub.com)
Zofran is an antiemetic prescription drug that is prescribed to prevent nausea and vomiting due to pregnancy, surgery, and cancer medications or procedures. (seagullindia.com)
Ondansetron 4mg is used to prevent nausea and vomiting that are caused by cancer chemotherapy. (snubiocare.in)
This is because Ondansetron 4mg has very little effect on nausea associated with motion sickness. (snubiocare.in)
Ondansetron and promethazine are used to prevent nausea and vomiting . (hdkino.org)
Ondansetron is an anti-nausea medication and promethazine is a phenothiazine. (hdkino.org)
Chemotherapy drugs increase secretion of serotonin, which stimulates serotonin (5-HT3) receptors in the brain, causing nausea and vomiting. (hdkino.org)
It is used as an antihistamine, sedative, and antiemetic (anti-nausea). (hdkino.org)
Ondansetron works by blocking certain chemicals in the body that can trigger nausea and vomiting. (alldiscountpills.com)
As with other antiemetics, routine prophylaxis is not recommended for patients in whom there is little expectation that nausea and/or vomiting will occur postoperatively. (pillintrip.com)
Ondansetron Medis Melt is indicated for the management of nausea and vomiting induced by cytotoxic chemotherapy and radiotherapy. (pillintrip.com)
Ondansetron Medis Melt is indicated for the prevention of post-operative nausea and vomiting (PONV). (pillintrip.com)
In patients where nausea and/or vomiting must be avoided postoperatively, Ondansetron Medis tablets are recommended even where the incidence of postoperative nausea and/or vomiting is low. (pillintrip.com)
Motion Sickness medications, also known as antiemetics, are drugs that suppress nausea and vomiting. (alcoholaddictioncenter.org)
Antiemetics are a heterogeneous group of drugs used to treat various causes of nausea and vomiting . (amboss.com)
Ondansetron is commonly used for generalized nausea . (amboss.com)
Aprepitant has little or no affinity for serotonin (5-HT 3 ), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CI NV). (lgmpharma.com)
Emeset 4 tablets 4mg contain the active ingredient ondansetron hydrochloride, an antiemetic used to treat nausea and vomiting caused by cancer chemotherapy and radiotherapy, also to prevent post-operative nausea and vomiting. (inhousepharmacy.vu)
Emeset 4 tablets 4mg contain ondansetron that is used to control nausea and vomiting caused by cancer chemotherapy by preventing the stimulation of nausea and vomiting caused by this cancer treatment. (inhousepharmacy.vu)
Your healthcare provider may prescribe a medicine called an antiemetic, such as trimethobenzamide, to help prevent nausea and vomiting. (rxlist.com)
5-HT3 receptor blockers reduce nausea and vomiting through the binding and inhibition of the serotonin receptors involved in this process. (nicerx.com)

These agents include dolasetron, ondansetron, and granisetron. (medscape.com)
Group A (n=30) received 40mcg/kg granisetron intravenously, group B (n=30) received 80mcg/kg ondansetron intravenously and group C (n=30) received 5 ml of normal saline by the same route 2 minutes before induction of general anaesthesia. (ispub.com)
These patients received 40 μg/kg granisetron in group A, Ondansetron (80 μg/kg) in group B and 0.9% saline in group C two minutes prior to induction of anesthesia. (ispub.com)
In this paper, we will report the results of randomized phase III study to evaluate the efficacy of palonosetron versus granisetron in the standard triplet antiemetic therapy for cisplatin-based HEC. (medscape.com)

These highlights do not include all the information needed to use ONDANSETRON HYDROCHLORIDE TABLETS, and ONDANSETRON ORALLY DISINTEGRATING TABLETS safely and effectively. (nih.gov)
Zofran tablets contain ondansetron hydrochloride dihydrate as the active ingredient. (alldiscountpills.com)

It belongs to a class of drugs known as antiemetics. (alldiscountpills.com)

[ 5-7 ] Palonosetron has several advantageous features over first-generation 5-HT 3 RA, such as a longer plasma elimination half-life and a higher affinity for the 5-HT 3 receptor. (medscape.com)
[ 8 ] In patients receiving moderately emetogenic chemotherapy (MEC), better CINV control was obtained with palonosetron than with a first-generation 5-HT 3 RA, [ 9 ] which supports current guideline recommendations for palonosetron use as a part of antiemetic premedication for MEC. (medscape.com)

Scopolamine, benztropine, and procyclidine are considered selective for M 1 receptors. (psychiatrist.com)

It is thought that chemotherapy, radiotherapy and surgery can cause the release of serotonin (5HT) from the cells of the small intestine, which stimulates 5HT3 receptors that are found on the vagal nerves in the intestines. (inhousepharmacy.vu)
There are also 5HT3 receptors in the chemoreceptor trigger zone (CTZ) of the area postrema in the brain, which is where the vomiting reflex originates, by sending nerve messages to the vomiting centre. (inhousepharmacy.vu)
It is thought that ondansetron in Emeset 4 also blocks the 5HT3 receptors in the CTZ and this also prevents activation of the vomiting centre in the brain. (inhousepharmacy.vu)
Ondansetron in Emeset 4 thereby blocks the 5HT3 receptors found in the peripheral nervous system in the intestine and the central nervous system in the brain. (inhousepharmacy.vu)
Chemotherapy is a cytotoxic cancer treatment that causes the release of serotonin (5HT) from the cells of the small intestine, which stimulates the 5HT3 receptors found on the vagal nerves in the intestines. (inhousepharmacy.vu)

Serotonin receptors of the 5-HT3 type are present both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone of the area postrema. (empr.com)
This inhibition of 5-HT 3 receptors in turn inhibits the visceral afferent stimulation of the vomiting center, likely indirectly at the level of the area postrema, as well as through direct inhibition of serotonin activity within the area postrema and the chemoreceptor trigger zone. (pharmfair.com)

Sensory conflict theory (the most widely accepted explanation for motion sickness) proposes that the condition is caused by conflict between the visual, vestibular, and somatosensory systems, and involves complex neurophysiologic signaling between multiple nuclear regions, neurotransmitters, and receptors. (cdc.gov)
Some antihistamines operate as antiemetics and are prescribed specifically for motion sickness. (alcoholaddictioncenter.org)

Such results are likely to be of use to clinicians prescribing these agents, as well as policy makers responsible for making decisions about antiemetic medications. (biomedcentral.com)
Antiemetic medications in children with presumed infectious gastroenteritis--pharmacoepidemiology in Europe and Northern America. (ox.ac.uk)
OBJECTIVE: To investigate the prescription pattern of antiemetic medications in 0- to 9-year-old children with infectious gastroenteritis in several industrialized countries during 2005. (ox.ac.uk)
Even certain medications can induce vomiting in some patients, so a patient may be prescribed an antiemetic to quell those unpleasant side-effects. (alcoholaddictioncenter.org)
Antiemetics include over-the-counter medications such as Pepto Bismol, Kaopectate, and Bismatrol. (alcoholaddictioncenter.org)
These medications can affect other serotonin receptors in your body which may lead to an increased incidence of side effects and drug interactions. (nicerx.com)
It has significant activity at only 5-HT3 receptors which helps its effectiveness at preventing emesis (vomiting) for longer periods when compared to first-generation medications. (nicerx.com)
The medications with the highest potential for actionability were analgesics, the antiemetic ondansetron, and antidepressants. (cdc.gov)

The active ingredient in Zofran is ondansetron. (alldiscountpills.com)

It blocks serotonin receptors in the vomiting center and on nerves supplying the digestive system. (mtatva.com)
Ondansetron ODT, for instance, blocks serotonin receptors and is used to treat chemotherapy patients, and others. (alcoholaddictioncenter.org)

The therapeutic effects occur through antagonism of central muscarinic acetylcholine receptors, the predominate type of cholinergic receptor in the brain. (psychiatrist.com)

Animal and human Positron Emission Tomography (PET) studies with Aprepitant have shown that it crosses the blood brain barrier and occupies brain NK1 receptors. (lgmpharma.com)
Fosaprepitant is a prodrug of aprepitant and accordingly, its antiemetic effects are attributable to aprepitant. (mdtodate.com)
Randomized controlled studies have shown that the addition of aprepitant to dexamethasone and a 5-HT 3 RA can achieve better CINV control when compared with the doublet antiemetic therapy. (medscape.com)
[ 3 , 4 ] Current antiemesis guidelines from multiple organizations [American Society of Clinical Oncology (ASCO), Multinational Association of Supportive Care in Cancer/European Society for Medical Oncology (MASCC/ESMO), and National Comprehensive Cancer Network (NCCN)] recommend aprepitant-containing triplet regimens as the standard antiemetic prophylaxis for patients receiving HEC. (medscape.com)

Antihistamines such as promethazine compete with histamine for one of the receptors for histamine (the H1 receptor) on cells. (hdkino.org)
However, when the antihistamines bind to the receptors they do not stimulate the cells. (hdkino.org)
IV paclitaxel includes the solubilizing agent Cremophor [2] (polyoxyethylated castor oil) which, although generally recognized as safe, has been shown to be responsible for significant side effects necessitating pre-treatment of patients with antiemetics, antihistamines and either oral or IV steroids. (doczz.net)

Commonly used older, traditional antiemetics for PONV were known to cause adverse effects such as dry mouth, dysphoria, sedation, hypotension, tachycardia, extra-pyramidal reactions, dystonic effects and restlessness leading to patient dissatisfaction 22 . (ispub.com)
High-risk PONV patients often require multiple antiemetics, including propofol anesthesia, as per consensus guidelines. (apsf.org)
It acts on multiple receptors involved in PONV, including dopaminergic, serotoninergic, and histaminergic receptors, with good oral bioavailability. (apsf.org)
The study found a 60% reduction in PONV incidence in the olanzapine group during the first 24 hours (p=0.008), even though both groups received the recommended multimodal antiemetic regimen. (apsf.org)
This study suggests that adding atypical antipsychotic medication like olanzapine, which targets multiple PONV receptors, to commonly used intraoperative antiemetic regimens can substantially reduce PONV and alleviate the associated challenges for both patients and healthcare systems. (apsf.org)

Initial antiemetic therapy may begin with routine doses of drugs commonly used to combat vomiting, such as promethazine, prochlorperazine, or droperidol. (medscape.com)
Pregnant women ≥18 years of age with NVP starting antiemetic therapy with promethazine, prochlorperazine, metoclopramide, or ondansetron at ≤ 16 weeks gestational age were eligible. (biomedcentral.com)

The information provided in Therapeutic indications of Ondansetron Medis is based on data of another medicine with exactly the same composition as the Ondansetron Medis . (pillintrip.com)
Be careful and be sure to specify the information on the section Therapeutic indications in the instructions to the drug Ondansetron Medis directly from the package or from the pharmacist at the pharmacy. (pillintrip.com)

Ondansetron is commonly used to treat HG, but studies are urgently needed to determine whether it is safer and more effective than using first-line antiemetics. (nature.com)

Brand names for ondansetron include Zofran , Zofran ODT , and Zuplenz. (hdkino.org)

Both groups received TIVA + epidural anesthesia, 4 mg of dexamethasone after induction, and 4 mg of ondansetron at the end of surgery. (apsf.org)

Other antiemetics work to suppress certain neurotransmitters, particularly dopamine and serotonin. (alcoholaddictioncenter.org)
SARIs act by binding to 5-HT2A receptors and blocking the reuptake of neurotransmitters such as serotonin, histamine, norepinephrine, and dopamine. (nicerx.com)

The correlations between hydroxytryptamine receptor 2A (HTR2A) gene polymorphisms (1438A/G, 102T/C, and rs7997012G/A) and the safety and efficacy of antidepressants in depression patients have been reported. (cdc.gov)

The objective of this study was to evaluate the role of serotonin receptor subunit HTR3A and HTR3B genotype with NVP severity and antiemetic efficacy. (biomedcentral.com)
Ondansetron, the only drug with evidence-based antiemetic efficacy, plays a minor role among antiemetic prescriptions. (ox.ac.uk)

Patients should be informed that ondansetron orally disintegrating tablets contain phenylalanine (a component of aspartame). (nih.gov)

The most common side effects of Ondansetron 4mg are constipation, diarrhea, fatigue, and headache. (snubiocare.in)
Side effects of ondansetron and promethazine that are similar include drowsiness and sedation, constipation , and dizziness . (hdkino.org)

Each tablet contains the specified dosage of ondansetron. (alldiscountpills.com)
The information provided in Dosage (Posology) and method of administration of Ondansetron Medis is based on data of another medicine with exactly the same composition as the Ondansetron Medis . (pillintrip.com)
500mg.org provides you with the chance to buy inexpensive Ondansetron 4, 8 mg online and also find out more about Ondansetron side effects, dosage information and drug interactions. (llclinic.com)

The antiemetic activity of the drug is brought about through the inhibition of 5-HT 3 receptors present both centrally (medullary chemoreceptor zone) and peripherally (GI tract). (pharmfair.com)

Patients known to have hypersensitivity (e.g. anaphylaxis) to ondansetron or any components of the formulation. (nih.gov)
If concomitant use of ondansetron with other serotonergic drugs is clinically warranted, patients should be made aware of a potential increased risk for serotonin syndrome. (nih.gov)
Consider antiemetics in patients with persistent vomiting. (medscape.com)
while in group B, 18 patients (45%) and in group C, 31 patients (77.5%) received antiemetics. (ispub.com)
The majority of women with NVP can be managed with dietary and lifestyle changes, but more than one-third of patients experience clinically relevant symptoms that may require fluid and vitamin supplementation and/or antiemetic therapy such as, for example, combined doxylamine/pyridoxine, which is not teratogenic and may be effective in treating NVP. (nature.com)
RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response. (cdc.gov)

The intake of Ondansetron 4mg causes dizziness and makes you drowsy, alcohol consumption can make you more drowsy. (snubiocare.in)

When histamine binds to its receptors on cells, it stimulates changes within the cells that lead to sneezing , itching , and increased mucus production. (hdkino.org)
Azelastine, an histamine 1 receptor-blocker, was predicted in multiple screens, and based on its attractive safety profile and availability in nasal formulation, was selected for experimental testing. (c19early.org)

Side effects of ondansetron that are different from promethazine include headache , feeling unwell (malaise), fatigue , diarrhea , and abnormal heart rate and rhythm. (hdkino.org)

Exclusion criteria included a history of allergy to drug(s), pregnancy & lactation, menstruation, vomiting or retching within 24 h before the operation, administration of antiemetic or psychoactive medication within 24 h before surgery, active alcohol or drug abuse. (ispub.com)
Severity of NVP was captured (using Pregnancy Unique Quantification of Emesis (PUQE) and Quality of Life (QOL) tools) upon enrollment and after one week of antiemetic therapy. (biomedcentral.com)

It is contraindicated in individuals who have a known hypersensitivity to ondansetron or any other components of the medication. (alldiscountpills.com)

Ondansetron (Zofran) vs. promethazine (Phenergan): What's the difference? (hdkino.org)
Ondansetron and promethazine belong to different drug classes. (hdkino.org)
What are ondansetron and promethazine? (hdkino.org)

Ondansetron may cause a condition that affects the heart rhythm (QT prolongation). (mtatva.com)

Blocks postsynaptic mesolimbic dopaminergic receptors in brain and reduces stimuli to brainstem reticular system. (medscape.com)

Ondansetron 4mg comes as a solution to be injected intravenously (into a vein) or intramuscularly (into a muscle) by a healthcare provider in a hospital. (snubiocare.in)

If you are allergic to any of the ingredients of Ondansetron 4mg then you should inform your doctor about it in order to avoid any severe side effects. (snubiocare.in)
Q. What are the side effects of Ondansetron 4mg? (snubiocare.in)
Furthermore, the many different types of antiemetics tend to have different side effects because they function differently in the body. (alcoholaddictioncenter.org)

It is not certain whether ondansetron's antiemetic action is mediated centrally, peripherally, or in both sites. (empr.com)

After being released, the serotonin binds to receptors in your stomach and transmits impulses through the central nervous system (CNS) to an area of your brain known as the vomiting center. (nicerx.com)

Acts centrally on chemoreceptor triggers in floor of fourth ventricle, which provides important antiemetic activity. (medscape.com)

Relaxes bronchial smooth muscle by action on beta2-receptors with little effect on cardiac muscle contractility. (medscape.com)

Anatomy1

Diseases8

Chemicals and Drugs21

Analytical, Diagnostic and Therapeutic Techniques and Equipment11

Phenomena and Processes3

Health Care4

Antagonist24

Antagonists17

Nausea24

Granisetron4

HYDROCHLORIDE2

Known as antiemetics1

Palonosetron2

Selective1

5HT35

Area postrema2

Motion sickness2

Medications8

Active ingredient1

Blocks serotonin receptors2

Muscarinic acetylcho1

Aprepitant4

Antihistamines3

PONV5

Prochlorperazine2

Indications2

Commonly1

Zofran ODT1

Dexamethasone1

Neurotransmitters2

Gene polymorphisms1

Efficacy2

Tablets1

Constipation2

Dosage3

Inhibition1

Patients6

Dizziness1

Histamine2

Headache1

Pregnancy2

Hypersensitivity1

Promethazine3

Prolongation1

Dopaminergic1

Intravenously1

Side Effects3

Peripherally1

Binds1

Centrally1

Cardiac1