• omental
  • Ex vivo omental organ co-culturing with luciferase-marked human OCa cells was developed to investigate the effect of 1,25D3 and VDR on the ability of OCa cells to invade omentum. (aacrjournals.org)
  • In ex vivo mouse models, the absence of the VDR in either the tumor cells or omentum resulted in increased invasiveness of OCa cells into omental tissues. (aacrjournals.org)
  • gastrocolic
  • Most sources include the following three: Gastrophrenic ligament-extends to the underside of the left dome of the diaphragm Gastrocolic ligament-extends to the transverse colon (occasionally on its own considered synonymous with "greater omentum") Gastrosplenic ligament (or Gastrolienal) ligament)- extends to the spleen, overlying the kidney The splenorenal ligament (from the left kidney to the spleen) is occasionally considered part of the greater omentum. (wikipedia.org)
  • mice
  • In in vivo studies with syngeneic tumor models, mouse ovarian tumors invaded into omentum much more rapidly in VDR null than wild type mice, showing a role for stromal VDR in OCa invasion. (aacrjournals.org)
  • Omentum Cells Promote Healing of Colonic Tissues in Dextran Sulfate Sodium (DSS) Induced Model of Colitis in Mice. (nih.gov)
  • We also examined if omentum infused mice were resistant to a lethal challenge of 4% DSS. (nih.gov)
  • 2% DSS-mice injected with omentum cells exhibited a decrease in body weight loss, decreased inflammation in the colon and decreased levels of the inflammatory cytokine KC in the serum compared to mice given 2% DSS alone. (nih.gov)
  • In addition, mice administered a lethal dose of 4% DSS exhibited a 50% decrease in mortality when injected with omentum cells. (nih.gov)
  • Mice were administered 2% DSS for 10 days and then injected intraperitoneally with omentum cells (2% DSS + omentum) or PBS (2% DSS). (nih.gov)
  • To determine if omentum protects against histological damage induced by DSS treatment, mice were administered 2% DSS for 10 days, injected with omentum cells and then euthanized 14 days later (day 24). (nih.gov)
  • In contrast, 2% DSS + omentum treated mice exhibited minimal ulcerations though they also showed extensive mucosal hyperplasia. (nih.gov)
  • In addition, we found that KC levels (functional homolog of interleukin-8) in the serum were also decreased in DSS + omentum mice compared to DSS treated mice (Fig. 3). (nih.gov)
  • inflammatory
  • In this study, we investigated whether the cells with anti-inflammatory and healing properties from the omentum could be harnessed to treat colitis in dextran sulfate sodium (DSS)-induced mouse colitis model. (nih.gov)
  • surgical
  • Omentectomy refers to the surgical removal of the omentum, a relatively simple procedure with no major side effects, that is performed in cases where there is concern that there may be spread of cancerous tissue into the omentum. (wikipedia.org)
  • Use of greater omentum in the surgical treatmen. (ugent.be)
  • Stegen L, Van Goethem B, Beerden C, Grussendorf C, De Rooster H. Use of greater omentum in the surgical treatment of a synovial cyst in a cat. (ugent.be)
  • resistant
  • The organ itself is strongly resistant to tumours - omentum cancer is known, but rare - but the filtering action of the milky spots can suck cancer cells into its fatty layers. (macedoniaonline.eu)
  • therapeutic
  • Randall and Meza-Perez suggest that better understanding the mechanism by which the omentum shields cancer cells could lead to new therapeutic targets, enabling early intervention. (macedoniaonline.eu)
  • our results demonstrate that omentum-derived ASCs are an alternative source of ASCs that regulate the antioxidant response and may represent a beneficial therapeutic strategy for ALF. (biomedcentral.com)
  • organ
  • Omentum merupakan jaringan lemak yang berada di dalam rongga perut yang berfungsi sebagai bantalan pelindung bagi organ dalam Anda. (blogspot.com)
  • addition
  • In addition, we performed in vitro co-culture studies with omentum-derived ASCs and primary isolated hepatocytes to demonstrate the hepatoprotective effect of omentum-derived ASCs on hepatocytes that were subjected to APAP-induced damage. (biomedcentral.com)