• monomeric
  • The binding affinities, obtained by isothermal fluorescence titration, of size-defined heparin and HS oligosaccharides to the chemokine were found to depend on the oligomerization state of IL-8: high affinity was detected for monomeric and low affinity was detected for dimeric IL-8, referring to a self-regulatory mechanism for its chemoattractant effect. (hud.ac.uk)
  • No indication for increasing affinities for monomeric IL-8 with increasing oligosaccharide chain length was found. (hud.ac.uk)
  • The monomeric composition of the oligosaccharides annotated in the library revealed that most of goat milk oligosaccharides have a lactose core and they are further decorated by functional groups. (milkgenomics.org)
  • studies
  • Numerous functional studies on human milk oligosaccharides (HMO) have concluded that these molecules perform important biological functions including the establishment of intestinal microbiota and prevention of pathogen binding to intestinal cells. (milkgenomics.org)
  • Recent studies have documented that these complex oligosaccharides are present in other mammalian milks, such as goat and bovine milk. (milkgenomics.org)