Klinefelter'sBoys with Klinefelter syndromeSymptomsInfertilityHypogonadismTherapy in Klinefelter patientsMales with Klinefelter syndromeDiagnosisTestesChromosomesPhenotypeHarry KlinefelterVariantsKaryotypeInfertile1942EndocrinologistTesticularSpermOccurs when a boyRisk of developing metabolAffectsMosaicismTurner syndromeIndividualsKallmannPubertyFetusesHereditaryTendClinicalConditionMale birthsPhenotypicPsychiatricPartners pregnantHormoneGenetic conditionsAdolescentFemalesExtra
Klinefelter's27
- Unfortunately, the infertility aspect of Klinefelter's is rarely treatable, although some Klinefelter males have become Dads thanks to an assisted reproduction technique called ICSI . (sharedjourney.com)
- Hypostatic ulcers in 47,XXY Klinefelter's syndrome. (uchicago.edu)
- PubMed was searched for 'Klinefelter,' 'Klinefelter's,' and 'XXY' in titles and abstracts. (mensfe.net)
- Clinical and therapeutic aspects of Klinefelter's syndrome: sexual function. (mensfe.net)
- Klinefelter's syndrome (KS) is the most common sex chromosomal aberration among men, with estimated prevalence of about 1 in 500 newborn males. (mensfe.net)
- Sexual dysfunction in subjects with Klinefelter's syndrome. (mensfe.net)
- The clinical significance of bone mineral density and testosterone levels in Korean men with non-mosaic Klinefelter's syndrome. (medscape.com)
- Rovenský J. Rheumatic diseases and Klinefelter's syndrome. (medscape.com)
- Genital anomalies in Klinefelter's syndrome. (medscape.com)
- 10th May is Klinefelter's Syndrome Awareness Day in the UK Klinefelter's Syndrome affects 1 in 600 males but 75% are never diagnosed. (ksa-uk.net)
- Men with Klinefelter's syndrome usually start testosterone replacement therapy (TRT) in early adolescence and take it life long. (excelmale.com)
- What are the symptoms of Klinefelter's syndrome? (artfertilityclinics.com)
- Klinefelter Syndrome often referred to as XXY trisomy, XXY syndrome, and Klinefelter's Syndrome is a chromosomal disorder exclusively associated with males having one or more of the X chromosome than the normal 'XY' pattern. (hxbenefit.com)
- What is Turner's and Klinefelter's Syndrome in psychology? (hellovaia.com)
- Although 10% of cases are diagnosed prenatally, two-thirds of people with the condition are unaware they have Klinefelter's Syndrome. (hellovaia.com)
- Klinefelter's Syndrome is when biologically male people (anatomically appear male) have an extra X chromosome, making their chromosome pattern XXY. (hellovaia.com)
- Klinefelter's syndrome is a condition in which men have an extra X chromosome in most of their cells - an XXY pattern instead of the normal XY pattern that most men have. (medwonders.com)
- Would you like to join the Klinefelter's Syndrome support group? (medwonders.com)
- Are you sure you want to be removed from the Klinefelter's Syndrome support group? (medwonders.com)
- Klinefelter's syndrome is best described as a genetic condition that affects the male child only. (premiumessays.net)
- Klinefelter's syndrome can also cause reduced muscle mass, facial hair, enlarged breast tissues and reduced body. (premiumessays.net)
- As earlier mentioned, Klinefelter's syndrome is not noticed until puberty which can come late if the male child has the syndrome. (premiumessays.net)
- The genetic variation of Klinefelter's syndrome cannot be reversed. (premiumessays.net)
- Foresta C, Galeazzi C, Bettella A, Marin P, Rossato M, Garolla A, Ferlin A. Analysis of meiosis in intratesticular germ cells from subjects affected by classic Klinefelter's syndrome. (springer.com)
- Palermo GD, Schlegel PN, Sills ES, Veeck LL, Zaninovic N, Menendez S, Rosenwaks Z. Births after intracytoplasmic injection of sperm obtained by testicular extraction from men with nonmosaic Klinefelter's syndrome. (springer.com)
- is determined in men when reduced testosterone production is suspected, e.g. in hypogonadism, estrogen therapy, chromosome aberrations (as in the Klinefelter's syndrome) and liver cirrhosis. (cdc.gov)
- Transsexual development of a patient with Klinefelter's Syndrome. (bvsalud.org)
Boys with Klinefelter syndrome5
- These treatments can help boys with Klinefelter syndrome who have problems with speech, language and muscle weakness. (mayoclinic.org)
- Some boys with Klinefelter syndrome have trouble learning and socializing and can benefit from extra assistance. (mayoclinic.org)
- Most boys with Klinefelter syndrome have normal or slightly decreased intelligence. (msdmanuals.com)
- Frequency of XY sperm increases with age in fathers of boys with Klinefelter syndrome. (medscape.com)
- Phenotype and Adverse Quality of Life in Boys with Klinefelter Syndrome. (qxmd.com)
Symptoms14
- The signs and symptoms of Klinefelter syndrome vary. (medlineplus.gov)
- Some Klinefelter males experience symptoms of their condition as boys or teenagers, and they therefore benefit from diagnosis and treatment at an earlier stage. (wdxcyber.com)
- Although some Klinefelter males will exhibit symptoms of the condition from boyhood, many don't realize that they have the condition until they try as adults to become fathers. (sharedjourney.com)
- Treatments are available for some symptoms of Klinefelter syndrome - for example, testosterone therapy can help men who have some feminine features. (sharedjourney.com)
- Klinefelter syndrome is named after Dr. Henry Klinefelter, who first described a group of symptoms found in some men with the extra X chromosome. (doctors.am)
- Even though all men with Klinefelter syndrome have the extra X chromosome, not every XXY male has all of those symptoms. (doctors.am)
- Because not every male with an XXY pattern has all the symptoms of Klinefelter syndrome, it is common to use the term XXY male to describe these men, or XXY condition to describe the symptoms. (doctors.am)
- What are the symptoms of Turner syndrome and Klinefelter syndrome symptoms? (hellovaia.com)
- Turner Syndrome and Klinefelter Syndrome symptoms present quite differently from one another. (hellovaia.com)
- Klinefelter syndrome has physical, psychological, and behavioural symptoms. (hellovaia.com)
- Here are the symptoms of Turner syndrome. (hellovaia.com)
- Effects of the syndrome will vary from one individual to another and not all the males portray the same symptoms and signs. (premiumessays.net)
- Many men with Klinefelter syndrome do not have obvious symptoms. (umcvc.org)
- It is named after Dr. Henry Klinefelter who first discovered the syndrome in 1942 and was able to link the symptoms back to men with an extra X chromosome. (clinicforhim.com)
Infertility7
- Klinefelter syndrome can make it difficult for people with this condition to have biological children (a condition called infertility), but up to half of people with Klinefelter syndrome may be able to have children using assisted reproductive technologies. (medlineplus.gov)
- If you or your son is diagnosed with Klinefelter syndrome, your health care team may include a doctor who specializes in diagnosing and treating disorders involving the body's glands and hormones (endocrinologist), a speech therapist, a pediatrician, a physical therapist, a genetic counselor, a reproductive medicine or infertility specialist, and a counselor or psychologist. (mayoclinic.org)
- Even if the problem is male-factor infertility, the chances of a man having Klinefelter syndrome are relatively low. (wdxcyber.com)
- An almost certain consequence of having the syndrome is permanent infertility. (sharedjourney.com)
- See our section on Klinefelter treatment, under Male Infertility: Drugs and Treatment, for more information. (sharedjourney.com)
- In Klinefelter syndrome (KS) the topic of fertility vs. infertility is of major concern since that, until recent years, infertility was considered an untreatable condition in KS. (springer.com)
- Infertility in patients with Klinefelter syndrome: optimal timing for sperm and testicular tissue cryopreservation. (springer.com)
Hypogonadism11
- Klinefelter syndrome is characterized by hypogonadism (micro-orchidism [small testes], oligospermia/azoospermia), gynecomastia in late puberty, hyalinization and fibrosis of the seminiferous tubules, elevated urinary gonadotropin levels, and behavioral concerns. (medscape.com)
- Management and treatment should focus on 3 major facets of the syndrome: hypogonadism, gynecomastia, and psychosocial problems. (medscape.com)
- The hypogonadism may lead to changes in body composition and a risk of developing metabolic syndrome and type 2 diabetes. (mensfe.net)
- Accordingly, clinical studies indicate that sexual dysfunctions, eventually present in KS, are not specifically associated with the syndrome but are related to the underlying hypogonadism. (mensfe.net)
- Classic Kallmann syndrome (KS) and idiopathic hypogonadotropic hypogonadism (IHH) are rare genetic conditions that encompass the spectrum of isolated hypogonadotropic hypogonadism. (medscape.com)
- By definition, either anosmia (lack of sense of smell) or severe hyposmia is present in patients with Kallmann syndrome, in contrast to patients with idiopathic hypogonadotropic hypogonadism, whose sense of smell is normal. (medscape.com)
- MRI of the brain in patients with Kallmann syndrome (KS) and idiopathic hypogonadotropic hypogonadism (IHH). (medscape.com)
- Deficient hypothalamic GnRH secretion underlies the markedly abnormal gonadotropin secretion patterns in most patients with Kallmann syndrome or idiopathic hypogonadotropic hypogonadism. (medscape.com)
- Some of the genes involved in the pathogenesis of Kallmann syndrome and idiopathic hypogonadotropic hypogonadism have been identified. (medscape.com)
- [ 3 ] In addition, mutations of the gene encoding chromodomain-helicase DNA-binding protein 7 ( CHD7 ) have been found in some patients with Kallmann syndrome or idiopathic hypogonadotropic hypogonadism, some of whom have features of the CHARGE syndrome (characterized by delayed growth and development, congenital cardiac defects, dysmorphic ears, hearing loss, coloboma of the eyes). (medscape.com)
- Loss-of-function mutations of critical components of the prokineticin pathway have been implicated in the pathogenesis of Kallmann syndrome and idiopathic hypogonadotropic hypogonadism. (medscape.com)
Therapy in Klinefelter patients1
- Zitzmann M, Depenbusch M, Gromoll J, Nieschlag E. X-chromosome inactivation patterns and androgen receptor functionality influence phenotype and social characteristics as well as pharmacogenetics of testosterone therapy in Klinefelter patients. (medscape.com)
Males with Klinefelter syndrome3
- An estimated 50% of males with Klinefelter syndrome can produce sperm. (wikipedia.org)
- A form of primary testicular failure occurs in males with Klinefelter Syndrome, with elevated gonadotropin levels due to lack of feedback inhibition by the pituitary gland. (medscape.com)
- A small percentage of males with Klinefelter syndrome are diagnosed before birth. (mayoclinic.org)
Diagnosis5
- Also called karyotype analysis, this test is used to confirm a diagnosis of Klinefelter syndrome. (mayoclinic.org)
- A combination of tests are used to diagnosis Klinefelter syndrome. (wdxcyber.com)
- A man who receives a positive diagnosis of Klinefelter syndrome will have to accept that it's very unlikely he'll ever biologically father a child. (wdxcyber.com)
- We aimed to investigate change over time in incidence, prevalence and age at diagnosis among Turner syndrome (TS), Klinefelter syndrome (KS), Triple X syndrome (Triple X) and Double Y syndrome (Double Y). (biomedcentral.com)
- The determination of testosterone in women is helpful in the diagnosis of androgenic syndrome (AGS), polycystic ovaries (Stein-Leventhal syndrome) and when an ovarian tumor, adrenal tumor, adrenal hyperplasia or ovarian insufficiency is suspected. (cdc.gov)
Testes4
- Individuals with Klinefelter syndrome typically have small testes that produce a reduced amount of testosterone (primary testicular insufficiency). (medlineplus.gov)
- Adult Klinefelter men may have smaller-than-average testes . (sharedjourney.com)
- Males with the syndrome are often infertile, but sometimes the testes develop enough to produce sperm. (msdmanuals.com)
- It's not all about the testes: medical issues in Klinefelter patients. (medscape.com)
Chromosomes7
- The syndrome is defined by the presence of at least one extra X chromosome in addition to a Y chromosome yielding a total of 47 or more chromosomes rather than the usual 46. (wikipedia.org)
- Klinefelter syndrome is the most common sex chromosome disorder in males and the second most common condition caused by the presence of extra chromosomes. (clinicalpub.com)
- Klinefelter syndrome (KS) refers to a genetic condition where the males have an extra chromosome making the total number of chromosomes 47 instead of 46 in healthy males. (artfertilityclinics.com)
- However, some syndromes can affect these sex chromosomes, causing many issues for those involved, known as atypical sex chromosome patterns (Klinefelter and Turner syndrome). (hellovaia.com)
- Turner's syndrome patients have 45 chromosomes rather than the usual 46. (hellovaia.com)
- Klinefelter syndrome occurs when a boy is born with one or more extra X chromosomes. (umcvc.org)
- Extant literature shows that Klinefelter syndrome (KS) is a chromosomal condition that affects the male physical, psychosocial and cognitive capacities due to the presence of one or more supernumerary X chromosomes among the affected individuals. (psychologywriting.com)
Phenotype6
- Klinefelter syndrome: expanding the phenotype and identifying new research directions. (uchicago.edu)
- Boada R, Janusz J, Hutaff-Lee C, Tartaglia N. The cognitive phenotype in Klinefelter syndrome: a review of the literature including genetic and hormonal factors. (medscape.com)
- An abnormal human female phenotype, called Turner syndrome , was described by H. H. Turner and associates 1938. (majordifferences.com)
- To characterize associations among psychosocial well-being, physical phenotype, and sex hormones in a sample of youth with Klinefelter syndrome (KS). (qxmd.com)
- Using an investigator-developed Klinefelter Phenotype Index Scale, the number of KS physical traits ranged from 1-13 (mean 5.1 ± 1.9). (qxmd.com)
- The Klinefelter Phenotype Index Scale may be a useful tool to characterize KS features in boys. (qxmd.com)
Harry Klinefelter1
- It is named after American endocrinologist Harry Klinefelter, who identified the condition in the 1940s. (wikipedia.org)
Variants1
- Visootsak J, Aylstock M, Graham JM Jr. Klinefelter syndrome and its variants: an update and review for the primary pediatrician. (medscape.com)
Karyotype4
- [ 1 ] The etiology was thought to be due to an endocrine disorder of unknown cause, until 1959, when Jacobs et al recognized that Klinefelter syndrome was a chromosomal disorder in which there is an extra X chromosome, resulting in the karyotype 47,XXY. (medscape.com)
- Today, the term Klinefelter syndrome (KS) refers to a group of chromosomal disorders in which the normal male karyotype, 46,XY, has at least one extra X chromosome. (medscape.com)
- If Klinefelter syndrome is not diagnosed prenatally, a patient with 47,XXY karyotype may demonstrate various subtle, age-related clinical signs that would prompt diagnostic testing. (medscape.com)
- Klinefelter syndrome (47, XXY) is a condition that occurs in men who have an extra X chromosome, resulting in an XXY sex chromosome karyotype. (healthguidenet.com)
Infertile1
- Until 1996, men with Klinefelter syndrome were considered infertile. (medscape.com)
19421
- In 1942, Klinefelter et al published a report describing nine men with a constellation of features: testicular dysgenesis, microorchidism, eunuchoidism, gynecomastia, elevated urinary gonadotropins, and azoospermia. (medscape.com)
Endocrinologist1
- This chromosomal condition was first observed and documented by Harry Fitch Klinefelter Jr, an American endocrinologist, and rheumatologist in the 40s, and hence its name. (hxbenefit.com)
Testicular5
- Adolescent male with Klinefelter syndrome who has female-type distribution of pubic hair and testicular dysgenesis. (medscape.com)
- Wikstrom AM, Dunkel L. Testicular function in Klinefelter syndrome. (medscape.com)
- The syndrome affects testicular growth adversely resulting to testicles that are smaller than normal. (premiumessays.net)
- Aksglaede I, Juul A. Testicular function and fertility in men with Klinefelter syndrome: a review. (springer.com)
- Plotton I, Giscard d'Estaing S, Cuzin B, Brosse A, Benchaib M, Lornage J, Ecochard R, Dijoud F, Lejeune H. Preliminary results of a prospective study of testicular sperm extraction in young versus adult patients with nonmosaic 47,XXY Klinefelter syndrome. (springer.com)
Sperm5
- Most men with Klinefelter syndrome are typically unable to father children because few or no sperm are produced in the testicles. (mayoclinic.org)
- There are men with Klinefelter syndrome all over the world who have become fathers through adoption, or assisted reproduction procedures using sperm from an anonymous donor. (wdxcyber.com)
- Often, the syndrome is not diagnosed till adulthood and most men with the syndrome will report to produce little to no sperm. (premiumessays.net)
- Objective To assess sperm retrieval rates in adolescents and young adults with Klinefelter syndrome, with the ultimate goal of improving fertility in this population. (elsevierpure.com)
- Conclusions This pilot study suggests that sperm retrieval rates in adolescents and young adults with Klinefelter syndrome are comparable with those reported in older men. (elsevierpure.com)
Occurs when a boy1
- Klinefelter syndrome occurs when a boy has one extra X chromosome. (msdmanuals.com)
Risk of developing metabol1
- People with Klinefelter syndrome have an increased risk of developing metabolic syndrome, which is a group of conditions that include high blood glucose levels during prolonged periods without food (fasting), high blood pressure ( hypertension ), increased belly fat, and high levels of fats (lipids) such as cholesterol and triglycerides in the blood. (medlineplus.gov)
Affects5
- Klinefelter syndrome, also called 47,XXY, is a chromosomal condition that affects development in people who are assigned male at birth. (medlineplus.gov)
- People with Klinefelter syndrome are more likely than those without Klinefelter syndrome to have autism spectrum disorder , which is a developmental disorder that affects communication and social interaction. (medlineplus.gov)
- Klinefelter syndrome affects about 1 in 650 newborns who were assigned male at birth. (medlineplus.gov)
- Klinefelter syndrome is a genetic condition that affects males. (umcvc.org)
- Marfan syndrome is an inherited disease that affects the body's connective tissue, which provides support, strength, and elasticity to blood vessels, cartilage, heart valves, tendons, and other important parts of the physical body. (healthguidenet.com)
Mosaicism1
- Survival of male patients with incontinentia pigmenti carrying a lethal mutation can be explained by somatic mosaicism or Klinefelter syndrome. (uchicago.edu)
Turner syndrome8
- But what happens when a biological male has an extra X chromosome (Klinefelter syndrome), and a biological female is missing an X chromosome (Turner syndrome)? (hellovaia.com)
- Finally, what are a few more interesting facts about Turner syndrome? (hellovaia.com)
- Before diving into Klinefelter and Turner Syndrome in psychology, let's be sure we know what a sex chromosome is. (hellovaia.com)
- Fig. 1 Blood testing for DNA is used to diagnose Klinefelter Syndrome and Turner Syndrome. (hellovaia.com)
- The Turner syndrome is due to monosomy X (45, X). This monosomic has a chromosome complement of 44 autosomes and one X chromosome (44+XO). (majordifferences.com)
- This is incorrect regarding turner Syndrome. (majordifferences.com)
- What characteristics a turner Syndrome girl has depends on how many of her cells were affected. (majordifferences.com)
- Also, only 1-2% of Turner Syndrome fetuses are born alive. (majordifferences.com)
Individuals5
- Individuals with Klinefelter syndrome may have have anxiety, depression , impaired social skills, or behavioral differences, such as emotional immaturity during childhood or difficulty with frustration. (medlineplus.gov)
- Treatment, health education and social support can greatly benefit individuals with Klinefelter syndrome. (mayoclinic.org)
- Fortunately, there are numerous treatment plans that can help individuals with KS lead an almost normal life as well as live as long as those who are unaffected by the syndrome. (hxbenefit.com)
- Individuals with Klinefelter Syndrome show reduced volume in several brain areas, including the amygdala, temporal and frontal regions, hippocampus, and insular cortex. (hellovaia.com)
- Individuals with this syndromes are phenotypically males but with tendency towards femaleness. (majordifferences.com)
Kallmann4
- Mutations of the KAL1 gene, which encodes a putative neural cell adhesion molecule (anosmin), have been described in several patients with X-linked Kallmann syndrome. (medscape.com)
- Loss-of-function mutations of the gene encoding fibroblast growth factor receptor 1 (FGFR1) have been described in patients with autosomal dominant Kallmann syndrome. (medscape.com)
- Mutations of the gene encoding fibroblast growth factor 8 have been found in a small minority of patients with autosomal dominant Kallmann syndrome. (medscape.com)
- [ 7 ] Homozygous, heterozygous or compound heterozygous mutations of the prokineticin receptor 2 have also been associated with Kallmann syndrome. (medscape.com)
Puberty4
- During puberty, the physical traits of the syndrome become more evident - because these boys do not produce as much testosterone as other boys, they have a less muscular body, less facial and body hair, and broader hips. (wikipedia.org)
- Having Klinefelter syndrome can be a challenge, especially during puberty and young adulthood. (mayoclinic.org)
- Note - since KS can be hard to notice, many parents don't know their child has the syndrome until he shows delays in puberty. (healthguidenet.com)
- Wikstrom AM, Raivio T, Hadziselimovic F, Wikstrom S, Tuuri T, Dunkel L. Klinefelter syndrome in adolescence: onset of puberty is associated with accelerated germ cell depletion. (springer.com)
Fetuses1
- An estimated 60% of pregnancies with fetuses having Klinefelter syndrome abort. (wikipedia.org)
Hereditary1
- Klinefelter syndrome is not a genetic or hereditary condition but transpires due to a randomized error in chromosomal patterning. (hxbenefit.com)
Tend2
- People with Klinefelter syndrome tend to have better receptive language skills (the ability to understand speech) than expressive language skills (vocabulary and the production of speech) and may have difficulty communicating and expressing themselves. (medlineplus.gov)
- Because men with Klinefelter syndrome tend to have low testosterone, they may have some physical characteristics that make them stand out from other men. (wdxcyber.com)
Clinical3
- Clinical review: Klinefelter syndrome--a clinical update. (mensfe.net)
- Bojesen A, Gravholt CH. Klinefelter syndrome in clinical practice. (medscape.com)
- Note - because of the high degree of variability of the syndrome, many of these clinical characteristics can be present at birth or they can manifest later in childhood. (healthguidenet.com)
Condition8
- Klinefelter syndrome (KS), also known as 47,XXY, is an aneuploid genetic condition where a male has an additional copy of the X chromosome. (wikipedia.org)
- Klinefelter males are born with the condition. (sharedjourney.com)
- The chances of you actually having Klinefelter syndrome are very small (somewhere between 1 in 500 and 1 in 1000 men have the condition). (sharedjourney.com)
- Klinefelter syndrome , also known as the XXY condition, is a term used to describe males who have an extra X chromosome in most of their cells. (doctors.am)
- Klinefelter syndrome (or 47,XXY or XXY syndrome) is a condition in which males have an extra X chromosome. (clinicalpub.com)
- Learn more about this condition from experts, meet others who have it, and network with them by joining our online support group for people with Klinefelters' syndrome. (medwonders.com)
- Klinefelter Syndrome (KS) is a condition that only occurs in men as a result of an extra X chromosome. (clinicforhim.com)
- Klinefelter syndrome is a rare genetic condition in which a male has an extra X chromosome. (cdc.gov)
Male births3
- Klinefelter syndrome is one of the most common chromosomal disorders, occurring in one to two per 1,000 live male births. (wikipedia.org)
- Klinefelter syndrome is the most common sex chromosome disorder and occurs in about 1 in every 500 live male births. (msdmanuals.com)
- One in every 500 male births is the victim of this syndrome. (majordifferences.com)
Phenotypic1
- Images reproduced from Quinton R, et al: The neuroradiology of Kallmann's syndrome: a genotypic and phenotypic analysis. (medscape.com)
Psychiatric1
- Psychiatric morbidity and X-chromosomal origin in a Klinefelter sample. (medscape.com)
Partners pregnant1
- Many men, however, find out that they have Klinefelter syndrome only after they try, and fail, to get their partners pregnant. (wdxcyber.com)
Hormone4
- Blood or urine samples can reveal abnormal hormone levels that are a sign of Klinefelter syndrome. (mayoclinic.org)
- Throughout their development, the syndrome prevents their bodies from producing enough of the male sex hormone testosterone. (sharedjourney.com)
- Klinefelter HF Jr, Reifenstein EC Jr, Albright F. Syndrome characterized by gynecomastia aspermatogenesis without a-Leydigism and increased excretion of follicle-stimulating hormone. (medscape.com)
- A longitudinal perspective of hormone replacement therapies (HRTs) on neuromotor capabilities in males with 47,XXY (Klinefelter syndrome). (bvsalud.org)
Genetic conditions1
- The syndrome might be identified in pregnancy during a procedure to examine fetal cells drawn from the amniotic fluid (amniocentesis) or placenta for another reason - such as being older than age 35 or having a family history of genetic conditions. (mayoclinic.org)
Adolescent1
- Adolescent male with gynecomastia and Klinefelter syndrome. (medscape.com)
Females1
- Turner's Syndrome occurs in biological females who lack an X chromosome, i.e. (hellovaia.com)
Extra6
- Klinefelter males are born with at least one extra X chromosome in each of their cells. (wdxcyber.com)
- In a nutshell, men with Klinefelter syndrome have an extra X chromosome. (sharedjourney.com)
- Most genes from the extra X undergo inactivation, but some escape and serve as the putative genetic cause of the syndrome. (mensfe.net)
- One in every 500 males has an extra X chromosome but does not have the syndrome. (clinicalpub.com)
- Klinefelter Syndrome is the result of an extra X chromosome (XYX). (clinicforhim.com)
- Klinefelter syndrome is when a male has developed an extra X chromosome. (catster.com)