Occurs recombination genetic. Medical search. Frequent questions

The RAD51 protein is required for mitotic and meiotic recombination, whereas the DNA repair protein, DMC1, is specific to meiotic recombination. (wikipedia.org)
Meiotic recombination is required in most organisms to ensure the correct segregation of chromosomes at meiosis I and to boost genetic diversity. (europa.eu)
In mammals, studies on the early stages of oogenesis face serious technical challenges in that entry into the meiotic cycle, meiotic recombination, and the initiation of the highly conserved prophase I arrest all occur during embryogenesis. (nih.gov)
Meiotic recombination contributes to genetic diversity and ensures the correct segregation of chromosomes. (nih.gov)
The history of research on meiotic recombination is long and rich. (fredhutch.org)
The mystery was this: how do cells protect centromeric regions from meiotic recombination? (fredhutch.org)

Viruses like SARS-CoV-2 continuously evolve as changes in the genetic code (caused by genetic mutations or viral recombination) occur during replication of the genome. (cdc.gov)
A variant is a viral genome (genetic code) that may contain one or more mutations. (cdc.gov)
10 These factors are not mutually exclusive and include the purity and length of the repeated sequence, 7, 11 age of individuals, 6, 7 mitotic drive, 12 the relative position of the TNR with respect to adjacent origins of DNA replication, 13 and mutations in genes involved in DNA repair, replication, and recombination. (bmj.com)
They can occur as point mutations or frameshift mutations and can be randomly introduced (spontaneous) or induced by exposure to a mutagen. (coursehero.com)
Mutations can also occur as a result of exposure to environmental factors such as chemicals, radiation, or viruses. (coursehero.com)
When bacteria replicate, some mutations that occur may be beneficial to the survival of the organism. (coursehero.com)
Antigenic drift occurs through accumulating mutations and environmental influences, and these gradual changes are why we get the flu every couple of years: changes accumulate until the body can no longer recognize the strain and consequently, it loses its ability to defend itself. (ubc.ca)
Within any population, there exists genetic diversity due to mutations and recombination during sexual reproduction. (raisinrats.com)
d, showed that mutations can occur any time in clonal growth. (nih.gov)
Below is a short free essay written on the topic of human mutations or recombinations. (customcollegeessays.com)
Individuals may vary through so-called modifications, through 'recombinations' and through 'mutations. (customcollegeessays.com)

The apparent increase in genetic variation observed in populations of P. infestans in western Washington from 1996 to 1997 most likely occurred by migration rather than by sexual recombination. (apsnet.org)
Salmonella typhimurium a, undergoes sexual recombination as does its relative E. coli. (nih.gov)
We present the first direct genetic evidence to support the occurrence of sexual recombination between compatible strains of A. flavus through the meiotic processes of independent assortment and crossing-over, both of which are likely to contribute to the maintenance and regeneration of the aflatoxigenic phenotype. (usda.gov)

During meiosis in eukaryotes, genetic recombination involves the pairing of homologous chromosomes. (wikipedia.org)
Recombination may also occur during mitosis in eukaryotes where it ordinarily involves the two sister chromosomes formed after chromosomal replication. (wikipedia.org)
In meiosis, non-sister homologous chromosomes pair with each other so that recombination characteristically occurs between non-sister homologues. (wikipedia.org)
In both meiotic and mitotic cells, recombination between homologous chromosomes is a common mechanism used in DNA repair. (wikipedia.org)
During meiosis, synapsis (the pairing of homologous chromosomes) ordinarily precedes genetic recombination. (wikipedia.org)
Chromosomal crossover involves recombination between the paired chromosomes inherited from each of one's parents, generally occurring during meiosis. (wikipedia.org)
Chromosomes (green) and their genetic recombination hotspots (red). (nih.gov)
Researchers have zoomed in on mouse chromosomes to map hotspots of genetic recombination - sites where DNA breaks and reforms to shuffle genes. (nih.gov)
Yes, crossing over occurs during synapsis when the chromosomes are bundled in tetrads. (ottovonschirach.com)
Explanation: Crossing over occurs when chromosomal homologs exchange information during metaphase of Meiosis I. During this stage, homologous chromosomes line up on the metaphase plate and exchange genetic information. (ottovonschirach.com)
Comparisons of meiosis among B. napus allohaploid plants, which carry one copy of each of the 10 A and 9 C B. napus chromosomes (AC), showed that allohaploids produced from different B. napus varieties displayed different levels of homeologous recombination. (europa.eu)
In humans, roughly 2-4 crossover events occur per chromosome, giving rise to subtle genetic differences observed between parents and children while also guiding the proper segregation of chromosomes during meiosis to form viable gametes (eggs and sperm in humans) and healthy progeny. (fredhutch.org)
There is good reason to prevent recombination and DSBs near the centromere as the centromere serves a critical function in parceling out chromosomes to daughter cells and defects in chromosome segregation can lead to genetic disorders such as Down syndrome. (fredhutch.org)
During DNA replication, proteins necessary for chromosome cohesion and recombination are deposited more or less uniformly along chromosomes. (fredhutch.org)
They experience recombination - where pieces of genetic material are swapped from matching chromosomes to form new mixtures of genes. (exploringnature.org)
The genomic architecture of this case is characterized by an undifferentiated genomic background interspersed by strong differentiation across multiple chromosomes, especially in low recombination regions and inversions enriched with quantitative trait loci (QTL) for divergent traits 3 , 19 . (nature.com)

A mutation refers to a single change in a virus's genome (genetic code). (cdc.gov)
A spontaneous mutation is a change in the genetic sequence that occurs randomly and without external influence. (coursehero.com)
The distributions of C11 and its parental haplotypes make it most likely that these two last steps occurred between the Middle East and the Indian subcontinent, with the A111T mutation occurring after the split between the ancestors of Europeans and East Asians. (blogspot.com)
The genetic basis of mutation rate [ 4 - 9 ] is the foundation for much theory [ 10 - 13 ]. (royalsocietypublishing.org)
Over many generations, genetic variations can accumulate within a population through mechanisms such as mutation, genetic recombination, and gene flow. (raisinrats.com)
d. mutation to streptomycin-resistance would be indicated if a very small amount of growth occurred in the streptomycin-con- taining region, but much growth occurred in the drug-free region. (nih.gov)

The shuffling of genes brought about by genetic recombination produces increased genetic variation. (wikipedia.org)
Genetic rearrangements in the cells that form sperm and eggs ensure that the set of genes passed on to every sperm and egg cell is unique. (nih.gov)
if PrBn and at least some of the mapped QTLs are duplicated genes retained from successive rounds of polyploidisation that still cooperate to regulate homeologous recombination, - if PrBn is still the key determinant for the level of homeologous recombination at the species level. (europa.eu)
By analyzing the whole genomes of Leishmania parasites, the researchers identified several genes which could allow the parasites to perform meiosis-like gene recombination. (nih.gov)
In other words, they have the necessary genes to perform a genetic recombination and exchange process similar to sexual reproduction in animals and plants. (nih.gov)
d. has n'its, each of which is capable of be- ing carried by a transducing phage, e. has some of its genes arranged in the same order as the chemical processes occur which these genes control. (nih.gov)
occur with vaccinia virus, leading to re- combination of its genes. (nih.gov)
Where most genetic diversity is to be found is in virus genes. (health-matrix.net)
Antibody diversity thus raises a special genetic question: How does an animal produce more antibodies than the genes in its genome? (1200artists.com)

Efforts to manipulate the chlamydial genome in vitro by recombination should be intensified. (nih.gov)
Recombination is known to occur at discrete regions of the genome called hotspots. (nih.gov)
Now that we have mapped recombination hotspots genome-wide, we can actually carry out studies on the whole mouse genome. (nih.gov)
The genomes of B. oleracea and B. rapa share an ancestral whole-genome triplication so that most segments of the Arabidopsis genome can be aligned to 6 syntenic segments of the B. napus genetic map. (europa.eu)
To address the first question, a comparative genetic analysis of all the QTL regions and their duplicates in the genome of B. napus was carried out. (europa.eu)
Combined bioinformatic and genetic approaches were used to determine which of the QTLs were located in syntenic regions of B. napus genome. (europa.eu)
The mechanism is prone to error but protects genome integrity from possible chromosomal translocations that can occur through homologous recombination. (news-medical.net)
It is initiated by the introduction of double-strand breaks (DSBs) and occurs in narrow regions of the genome called hotspots. (nih.gov)
The application of genetic diversity mining and genome editing for crop improvement has been hampered by the lack of tools and process to address the low frequency of Homologous Recombination (HR) that occurs in plants. (danforthcenter.org)
Even with the drastic differences in pathogenicity, C. muridarum and C. trachomatis share ~98% genome sequence identity, with most of the genetic differences occurring within the plasticity zone. (ku.edu)
Analyzing sequences of mitochondrial genome regions provides more reliable evidence regarding the genetic diversity and evolutionary origin of the species, due to the high rate of mitochondrial genome evolution compared to the nucleus. (researchgate.net)
The genome is the entire set of genetic instructions found in a cell. (visionlearning.com)
Phased haploblocks, similarly to other multi-allelic markers, will therefore be advantageous in genetic tasks like linkage mapping, QTL mapping and genome-wide association studies. (biomedcentral.com)

Meiosis is important for three main reasons: it allows sexual reproduction of diploid organisms, it enables genetic diversity, and it aids the repair of genetic defects. (ottovonschirach.com)
Loss of species diversity will bring a detriment to our planetary genetic resources on a time scale since the last mass extinction of around 65 million years. (dhushara.com)
This recombination process creates genetic diversity at the gene level that reflects differences in DNA sequences from different organisms. (1200artists.com)
The lack of reduced diversity within genomic islands and of genomic background differentiation led us to hypothesize that ecotypes likely diverged in situ in Lake Constance, either from selection on standing genetic variation or admixture variation. (nature.com)

In eukaryotes, recombination during meiosis is facilitated by chromosomal crossover. (wikipedia.org)
The researchers plan to use this map to further understand evolution as well as chromosomal abnormalities brought on by recombination. (nih.gov)
Prevention of chromosomal crossover events near the centromere, also known as pericentric regions, could occur at one of several steps leading up to DSB formation. (fredhutch.org)
By examining the roles of individual protein components of chromosome cohesion and recombination complexes, Smith and Nambiar discovered a dual role for the Swi6 protein, which localizes to the pericentric regions but not to chromosomal arms, that neatly provides the solution to the long-standing question. (fredhutch.org)

Homologous Genetic Recombination - Involves genetic exchanges between two DNA molecules. (tutorialspoint.com)
Homologous recombination involves the exchange of nucleotide sequences to repair damaged bases on both strands of DNA through the utilization of a sister chromatid. (news-medical.net)
What occurs in prophase of meisosi that involves genetic recombination? (freezingblue.com)

The obvious answer is recombination, which can readily occur when two strains of viruses infect a cell at the same time. (i-sis.org.uk)
But neither of the two progenitor strains is known, says Luis Enjuanes from the Universidad Autonoma in Madrid, Spain, one of the world leaders in the genetic manipulation of coronaviruses. (i-sis.org.uk)
NIAID supports a Tropical Medicine Research Center (TMRC) in Sri Lanka, which has conducted epidemiological and molecular studies on locally occurring types of Leishmania , comparing it with strains from India. (nih.gov)
Influenza pandemics occur when a new strain emerges that is different enough from previous strains that our immune systems cannot recognize it, rendering us defenseless. (ubc.ca)
Antigenic shift is a result of the recombination of genetic material from different strains, and can occur whenever an animal or human is infected with two different strains at once. (ubc.ca)
Because parents and offspring are genetically similar, they may be susceptible to the same parasite strains and thus, in hosts, maternal transmission should select for mechanisms that decrease intergenerational genetic similarity. (royalsocietypublishing.org)
Mixed infections involving different strains of a virus a. do not occur with tobacco mosaic virus al- though they do occur with influenza virus. (nih.gov)

Here we identify extensive sex differences at the initiation of recombination by mapping hotspots of meiotic DNA double-strand breaks in male and female mice. (nih.gov)
Direct mapping of meiotic DSBs in human individuals: novel aspects of recombination initiation. (nih.gov)

The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles. (mcw.edu)
It is well known that in mammalian somatic cells, mitotic recombination And can be modulated by genetic background. (1200artists.com)

What are three ways meiosis leads to genetic variation? (ottovonschirach.com)
Crossing over also accounts for genetic variation, because due to the swapping of genetic material during crossing over, the chromatids held together by the centromere are no longer identical. (ottovonschirach.com)
The occurrence of pathogenic variation, specifically physiologic races, has been based on several criteria but not yet by the traditional method of inoculating differential hosts and determining if infection occurs. (apsnet.org)
This article explores evolution from an informational perspective, delving into the mechanisms behind genetic variation, natural selection, and speciation. (raisinrats.com)
This genetic variation provides the raw material upon which natural selection acts. (raisinrats.com)
Breeding can be another reason for variation in form or recombination. (customcollegeessays.com)
Ecological speciation can sometimes rapidly generate reproductively isolated populations coexisting in sympatry, but the origin of genetic variation permitting this is rarely known. (nature.com)

In eukaryotes, genetic recombination during meiosis can lead to a novel set of genetic information that can be further passed on from parents to offspring. (wikipedia.org)
In meiosis and mitosis, recombination occurs between similar molecules of DNA (homologous sequences). (wikipedia.org)
Does crossing over occur in both mitosis and meiosis? (ottovonschirach.com)
This occurs in prophase of meiosis I. How many rounds of cell division occur? (ottovonschirach.com)
In meiosis-II the separation of two chromatids occur so that equal number of chromatids (in fact chromosome due to duplication of genetic material) goes to each of the daughter cell. (ottovonschirach.com)
Does meiosis occur all the time? (ottovonschirach.com)
In the Body Because mitosis takes place throughout your lifetime and in multiple organs, it occurs more often than meiosis, which is limited to the reproductive organs during gamete formation. (ottovonschirach.com)
Does crossing over occur in meiosis 2? (ottovonschirach.com)
Meiosis can only occur in eukaryotic organisms. (ottovonschirach.com)
Meiosis I includes crossing over or recombination of genetic material between chromosome pairs, while meiosis II does not. (ottovonschirach.com)
Meiosis occurs in the primordial germ cells, cells specified for sexual reproduction and separate from the body's normal somatic cells. (ottovonschirach.com)
In preparation for meiosis, a germ cell goes through interphase, during which the entire cell (including the genetic material contained in the nucleus) undergoes replication. (ottovonschirach.com)
Genetic recombination (crossing over) only occurs in meiosis I. (ottovonschirach.com)
Does meiosis occur before or after fertilization? (ottovonschirach.com)
Meiosis occurs over two cycles of cell division, which sperm cells complete before fertilization. (ottovonschirach.com)
Meiosis and recombination are among the most important processes because they are essential to the life cycle of all sexual eukaryotes. (europa.eu)
Meiosis is a type of cell division that occurs only in the specialized cells called germ cells. (proprofs.com)
Therefore, the statement that meiosis only occurs in germ cells is correct. (proprofs.com)
Metaphase of meiosis II until fertilization occurs. (freezingblue.com)
reorganization occurs in Two DNA molecules exchange fragments of their genetic material with each other … The unique combination of alleles that all sexually reproducing organisms acquire from their parents is a direct result of recombination during meiosis. (1200artists.com)

Because recombination can occur with small probability at any location along chromosome, the frequency of recombination between two locations depends on the distance separating them. (wikipedia.org)
[ 1 ] Its genetic cause is a microdeletion of chromosome 22 at band q11.2. (medscape.com)
if this would occur, multiple or illegitimate associations would result in chromosome misegregation and partial fertility. (europa.eu)
The Rec8-Rec11 complex along chromosome arms activates Spo11 leading to recombination, while the Rec8-Pcs3 complex along with Swi6 prevents Spo11 activation at pericentromeres. (fredhutch.org)

Researchers have recently identified recombination hotspots in humans. (nih.gov)
But these hotspots were mapped from a large pool of people with different genetic backgrounds and at a resolution that didn't allow for fine analysis. (nih.gov)

Does class switching occur before somatic hypermutation? (1200artists.com)

2) intrachromosomal recombination, occurring through crossing over. (wikipedia.org)

Genetic recombination and recombinational DNA repair also occurs in bacteria and archaea, which use asexual reproduction. (wikipedia.org)
Bacterial recombination In Bacteria there are regular bacterial recombination, as well as noneffective transfer of genetic material, expressed as unsuccessful transfer or abortive transfer which is any bacterial DNA transfer of the donor cell to recipients who have set the incoming DNA as part of the genetic material of the recipient. (wikipedia.org)
There are two ways by which transposition occurs in bacteria. (tutorialspoint.com)
Through horizontal gene transfer, MRSA continued to spread this genetic material to other Staphylococcus bacteria. (coursehero.com)
The fertilization process in bacteria always a. produces recombination. (nih.gov)
Genetic recombination in bacteria 15. (nih.gov)

Recombination can be artificially induced in laboratory (in vitro) settings, producing recombinant DNA for purposes including vaccine development. (wikipedia.org)
In our efforts to understand which genetic components are responsible for ascension, in vitro recombination between C. trachomatis and C. muridarum was completed, enriching for recombination around this plasticity zone. (ku.edu)

The third excision mechanism is called mismatch repair and occurs when mismatched bases are incorporated into the DNA strand during replication and are not removed by proofreading DNA polymerase. (news-medical.net)

The rearrangement of genetic information within and among DNA molecules encompasses a variety of processes, collectively placed under the heading of genetic recombination. (tutorialspoint.com)

Diplotene of prophase I, until puberty occurs. (freezingblue.com)

An important consequence of genetic anticipation is that the genetic transmission is interrupted and, therefore, new pathogenic alleles have to be generated from unexpanded alleles. (bmj.com)
If we consider a set of tightly linked bi-allelic markers (e.g. single-nucleotide polymorphisms, SNPs with only two alleles in the population studied) as one genetic locus, then the haplotypes covering these markers can be interpreted as the alleles of that locus. (biomedcentral.com)

These results suggest that AS3MT is the primary genetic locus responsible for the unique pattern of iAs metabolism in humans. (nih.gov)
Which of these two conflicting effects predominates depends on the strength of maternal transmission and the rate of recombination between the selected locus and the modifier. (royalsocietypublishing.org)

SARS-CoV-2, the virus that sparked the pandemic, probably emerged and infected humans through an initial small-scale exposure that occurred no later than November 2019. (idsa.in)
This type of photoreactivation does not occur in humans. (news-medical.net)
Antigenic shifts are probably due to genetic recombination (an exchange of a gene segment) between influenza A viruses that affect humans and/or animals. (cdc.gov)
The individual maps revealed that PRDM9, a protein identified as the major determinant of the location of DSBs in mammals, defines most of the sites where recombination happens in humans. (nih.gov)

The lineage that results from recombination is called a "recombinant. (cdc.gov)
Where does the recombination of Vdj recombinant somatic cells take place? (1200artists.com)
The locations of the crossover breakpoints within the aflatoxin cluster of the recombinant F1 progeny from our mating studies corroborate with those deduced from the genetic analysis of natural populations. (usda.gov)

Signs of the disease on pine occur as the fungus develops and produces two of the five spore stages characteristic of the rust. (apsnet.org)

Faulty recombination can lead to infertility or birth defects, and this work brings us closer to our ultimate goal of helping to prevent these health issues. (nih.gov)
It arises from a faulty recombination event during the development of sperm or egg cells. (sciencedaily.com)

That observation is that crossover events can occur almost anywhere along each of a chromosome's arms except for the central region, or centromere. (fredhutch.org)
I used molecular approaches to characterize regions of crossover among the hybrid progeny, focusing on hybrids containing gyrA-2 from C. muridarum as an indicator for genetic exchange near the plasticity zone. (ku.edu)

Speciation occurs when populations become reproductively isolated from one another, meaning they can no longer interbreed and produce fertile offspring. (raisinrats.com)

31 Therefore, we have hypothesised that mutagenic stress could result in an induction of instability of unexpanded TNR sequences, leading to an increase in the frequency of spontaneously occurring contractions/expansions in repeat number. (bmj.com)
Does the disorder occur in a greater frequency within a line or breed than in the general population? (vin.com)

As time goes on, this genetic trait is selected for, driving evolution of the species. (coursehero.com)
Is the same syndrome found in another species and is it known to be genetic? (vin.com)
Understanding how such changes occur requires examining various factors that influence species change. (raisinrats.com)
There is a group of viral species known as retroviruses which insert their genetic material into the host cell's DNA. (health-matrix.net)

Insertion of transposition in an essential gene could kill the cell that is why the process of transposition is very tightly regulated to avoid this and it does not occur frequently. (tutorialspoint.com)

A protein essential to make DSBs and thus recombination is Spo11, a protein relative of the topoisomerases, enzymes that create transient DSBs to relieve torsional stress. (fredhutch.org)

Since many clinically relevant serotypes within a serogroup have only small genetic differences, sequence-based assays have been pursued in addition to pyrosequencing. (medscape.com)
The differences between human genomes are small, but small changes in the code, called single nucleotide polymorphisms (SNPs) , if they occur in a protein sequencing area, can produce different proteins then the body intended. (exploringnature.org)

The researchers isolated and sequenced sites that were bound by a protein known to be involved in recombination. (nih.gov)
When this occurs early in the DNA sequence, the end protein produced is highly altered from the original. (coursehero.com)

6- 8 Expansions in the number of TNRs are known to be a molecular basis of genetic anticipation, 9 the progressively earlier age of onset of a disease with increasing severity in successive generations. (bmj.com)
It also introduces the student to the continuity of life from genetic and molecular perspectives. (uaeu.ac.ae)
Easy access to the early stages of oogenesis, coupled with available genetic and molecular genetic tools, makes Drosophila an excellent model for studies on meiotic progression and oocyte development. (nih.gov)
Much of the research revolves around the work of molecular geneticist Julie R. Korenberg, a professor in the Department of Pediatrics at UCLA and an adjunct professor at the Salk Institute, who has been studying the genetic basis of Williams syndrome for the last decade. (sciencedaily.com)
With the recent advances in molecular genetics and the availability of genetic maps, we have witnessed the emergence of genomics into clinical veterinary practice. (vin.com)

and reasons for emergence of virulent subtypes are poorly understood because of availability of only limited genomic sequence data and lack of robust cultivation systems and genetic manipulation tools ( 13 ). (cdc.gov)

There are two main mechanisms for repairing double strand breaks: homologous recombination and classical nonhomologous end joining. (news-medical.net)
These mechanisms are mutagenic and can lead to a loss in genetic information. (news-medical.net)
CHARACTERIZATION AND TREATMENT OF GENETIC METABOLIC DISEASES NIH GUIDE, Volume 23, Number 7, February 18, 1994 PA NUMBER: PA-94-036 P.T. 34 Keywords: Metabolic Diseases Genetics Pathophysiology Treatment, Medical+ National Institute of Diabetes and Digestive and Kidney Diseases PURPOSE The purpose of this program announcement is to encourage research grant applications studying the mechanisms underlying the pathophysiology of genetic metabolic diseases. (nih.gov)
RESEARCH OBJECTIVES The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) supports research on identifying and understanding the basic defects in causing genetic metabolic diseases, identifying alternative metabolic pathways, characterizing toxic metabolites and the mechanisms of their effects on multiple organs, development of animal models for these disorders, and treatment of these disorders including enzyme replacement therapy, dietary therapy, drug therapy and gene therapy. (nih.gov)

Genetic recombination (also known as genetic reshuffling) is the exchange of genetic material between different organisms which leads to production of offspring with combinations of traits that differ from those found in either parent. (wikipedia.org)
V(D)J recombination in organisms with an adaptive immune system is a type of site-specific genetic recombination that helps immune cells rapidly diversify to recognize and adapt to new pathogens. (wikipedia.org)
By examining how genetic information is passed down through generations and how it interacts with environmental factors, we can gain a deeper insight into how organisms adapt and evolve. (raisinrats.com)

Another criteria for pandemic status is that the virus must be easily transmissible, and potent enough that very few viral particles are required for an infection to occur. (ubc.ca)
Various researchers have brought to our attention the concept of viral recombination: when two viruses meet, they are very effective at exchanging genetic material between each other and a new recombined virus can be generated from this exchange. (health-matrix.net)

We demonstrated that sexual reproduction in A. flavus is heterothallic and occurs between individuals belonging to different vegetative compatibility groups, which suggests that the vegetative compatibility system is not a barrier to gene flow. (usda.gov)

[ 4 ] The cardiac defects are usually of the conotruncal type, which occur secondary to abnormal development of the outflow portion of the developing heart. (medscape.com)
Recent evidence suggests that many meiotic errors occur downstream of defects in the signaling pathways that control oocyte growth and differentiation. (nih.gov)
Research should be aimed at elucidating the genetic defects, examining their metabolic consequences, and devising and testing possible therapies for this group of devastating diseases. (nih.gov)

Gene conversion - the process during which homologous sequences are made identical also falls under genetic recombination. (wikipedia.org)
The three omp1 sequences were hybrids of serovars L1 and L2, containing a putative DNA recombination site in variable segment 2. (nih.gov)
Certain genetic sequences called haplotypes are passed on only by males or by females, so to get a complete picture of the ancestry of a population, scientists generate one family tree based on the male line and another based on the female line. (visionlearning.com)
Haplotypes are genetic sequences that we inherit from only one parent. (visionlearning.com)

d. do not occur for viruses containing RNA. (nih.gov)

In some transposons which are well characterized, the cointegrate intermediate is converted into a product by site-specific recombination, in which an enzyme called recombinase mediates the deletion reaction. (tutorialspoint.com)

We conducted sequence analyses of 32 genetic loci of 53 C. hominis specimens isolated from a longitudinally followed cohort of children living in a small community. (cdc.gov)
We identified by linkage disequilibrium and recombination analyses only limited genetic recombination, which occurred exclusively within the 60-kDa glycoprotein gene subtype IbA10G2, a predominant subtype for outbreaks in industrialized nations and a virulent subtype in the study community. (cdc.gov)
For genetic analyses, multi-allelic markers have an advantage over bi-allelic markers like SNPs (single nucleotide polymorphisms) in that they carry more information about the genetic constitution of individuals. (biomedcentral.com)

Somatic recombination is a gene rearrangement through which Cells of the adaptive immune system physically cut out small regions of DNA and glue the remaining DNA fragments together in error-prone ways . (1200artists.com)

An accidental - apparently small-scale - environmental leakage of the virus most likely occurred in Wuhan prior to November, considering various concrete, though circumstantial, evidence. (idsa.in)
Another evidence against the recent hypothesis that Amerindians carry West Eurasian admixture postulated to have occurred after Amerindians had split from East Asians. (blogspot.com)

We conducted a comparative population genetic analysis of virulent C. homini s subtype IbA10G2 in children living in a periurban community in Lima, Peru, by multilocus sequence typing (MLST) of 32 genetic markers. (cdc.gov)
Site-specific recombination- Exchange occurs only at a particular DNA sequence. (tutorialspoint.com)
This sequence of pycnial and aecial development occurs progressively each year as the canker grows and continues as long as the fungus remains active. (apsnet.org)
A codon is a DNA or RNA sequence of three nucleotides (a trinucleotide) that forms a unit of genetic information encoding a particular amino acid. (genome.gov)
The aim of this study was to use the sequence of mitochondrial control region to investigate the phylogenetic relationship and genetic distances between some domestic sheep breeds of Iran and other Middle Eastern countries. (researchgate.net)
This study provided additional proof for the use of control region sequence as a precise method of genetic distance estimation among sheep breeds. (researchgate.net)

At least four pandemics of influenza occurred in the 19th century, three in the 20th century, and one thus far in the 21st century. (cdc.gov)
Drift occurs in all three types of influenza virus (A, B, C). (cdc.gov)

Mammalian spermatogenesis is a high regulated biological process occurring in the seminiferous tubules in the testis. (intechopen.com)

Implications of recombination on mycotoxin heritability are currently under investigation. (usda.gov)

While in this formation, homologous sites on two chromatids can closely pair with one another, and may exchange genetic information. (wikipedia.org)

Crossing over is the swapping of genetic material that occurs in the germ line. (ottovonschirach.com)
Recombinations consist in changes in the form of offspring as compared with that of their progenitors, these being exactly proportional to the genetic qualities of such progenitors, and germ characters transmitted definitely in accordance with the laws of heredity. (customcollegeessays.com)

V(D)J recombination is a mechanism of somatic recombination that occurs only in Formation of lymphocytes during early stages of T and B cell maturation . (1200artists.com)

They used precursors of mouse sperm cells for their study because they needed a population with a specific and identical genetic background. (nih.gov)
In what anatomical location does the process of somatic reorganization in B cells occur? (1200artists.com)
Somatic reorganization occurs in Bone marrow (B cells) and thymus (T cells) in the absence of antigen, the antigen-independent stage. (1200artists.com)
Does recombination occur in somatic cells? (1200artists.com)

Pathways to Discovering the Cause of Disease: Could it be Genetic? (vin.com)

This region may indicate a recombination hotspot or chi site within Chlamydia or may highlight the selective pressure against C. trachomatis to harbor the cytotoxins. (ku.edu)

What must occur in order for sperm to penetrate the zona pellucid? (freezingblue.com)

The same thing happens with genetic recombination and if you attempt to track a certain trait backward more than a couple generations, you'll have a very difficult time, considering how many ancestors there are to consider. (visionlearning.com)

A virus may have DNA or RNA, and the type of genetic material depends on the function and nature of the virus. (health-matrix.net)

The distributions of C11 and its parental haplotypes make it most likely that these two last steps occurred between the Middle East and the Indian subcontinent,' Looks to me more like between West Asia (minus Arabia) and western part of South_Central Asia (minus India). (blogspot.com)

Anatomy18

Organisms16

Diseases6

Chemicals and Drugs73

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes147

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science5

Health Care4

Meiotic recombination6

Mutations11

Sexual recombination3

Chromosomes16

Mutation6

Genes9

Genome13

Diversity4

Chromosomal4

Involves3

Strains7

Initiation2

Mitotic2

Variation7

Meiosis20

Chromosome4

Hotspots2

Somatic hypermutation1

Intrachromosomal1

Bacteria6

Vitro2

Replication1

Molecules1

Prophase1

Alleles2

Locus2

Humans4

Recombinant3

Produces1

Faulty2

Crossover2

Populations1

Frequency2

Species4

Transposition1

DSBs1

Differences2

Protein2

Molecular5

Genomic1

Mechanisms4

Organisms3

Viral2

Gene flow1

Defects3

Sequences4

Viruses1

Recombinase1

Analyses3

Rearrangement1

Evidence2

Sequence6

Influenza2

Mammalian1

Implications1

Exchange genetic1

Germ2

Mechanism1

Cells4

Pathways1

Chlamydia1

Sperm1

Trait1

Material1

Haplotypes1