Occurs protein biosynthesis. Medical search. Frequent questions

Proteins perform a number of critical functions as enzymes, structural proteins or hormones. (wikipedia.org)
We show that this reproductive blockage is the result of a dramatic impairment of JH biosynthesis, due to the CA-specific reduction in the expression of two key JH biosynthetic enzymes, 3-hydroxy-3-methylglutaryl coenzyme A synthase-1 (BgHMG-S1 ) and HMG-reductase (BgHMG-R ). Our findings provide insights into the regulatory mechanisms underlying the specific changes in the CA gland necessary for the proper transition to adulthood. (nature.com)
The ring contraction process that occurs during cobalamin (vitamin B12) biosynthesis is mediated via the action of two enzymes, CobG and CobJ. (edu.au)
Decreases in these enzymes have been shown to lead to increased TAG production as fatty acid biosynthesis is favoured. (biomedcentral.com)
Deubiquitinylating enzymes (DUBs) regulate the deubiquitinylation process of post-translationally modified proteins and thus control protein signaling in various cellular processes. (bvsalud.org)
Beyond being the basis for muscle growth, amino acids are essential for synthesizing proteins, enzymes, hormones, neurotransmitters and just about every other body function you can name. (allstarhealth.com)
For more than 30 years, his main research interests have been the functional and structural study of the enzymes of peptidoglycan biosynthesis, the determination of the structure of peptidoglycan from certain bacterial species, and the search for peptidoglycan biosynthesis inhibitors that could act as antibacterial agents. (degruyter.com)
Like most enzymes of peptidoglycan biosynthesis, MurD constitutes an attractive target for the design and synthesis of new antibacterial agents. (degruyter.com)

Lead's high affinity for sulfhydryl groups makes it particularly toxic to multiple enzyme systems including heme biosynthesis. (cdc.gov)

Suspect genes encode proteins involved in central metabolic pathways, cell signaling, cell wall biosynthesis, pigment biosynthesis, and secondary metabolite production. (sciencedaily.com)
Plastids are also the location of a number of vital metabolic pathways, including primary carbon metabolism and the biosynthesis of fatty acids, amino acids, and tetrapyrroles. (frontiersin.org)

This Review summarizes the more recent biochemical, cellular and mouse model studies that underscore the importance of the ER acetylation process in maintaining protein homeostasis and autophagy within the secretory pathway, and its impact on developmental and age-associated diseases. (biologists.com)
13 C-tracing verified de novo biosynthesis of valine and further revealed build-up of pathway intermediate 2,3-dihydroxy-3-isovalerate. (elifesciences.org)
One of these genes, let-60 , encodes a Ras protein that functions as aswitch in the pathway of vulval induction. (pdfdrugs.com)
The data provided herein suggest that B. fragilis uses N-succinyl-L-ornithine rather than N-acetyl-L-ornithine for de novo arginine biosynthesis and therefore that this pathway in Bacteroides is different from the canonical arginine biosynthetic pathway of most organisms. (nih.gov)
He is director of research at CNRS and, since 2001, is the head of the Laboratory of Bacterial Envelopes and Antibiotics which, for more than 30 years, has been studying the biochemistry, genetics and physiology of the bacterial cell-wall peptidoglycan biosynthesis pathway as a whole. (degruyter.com)
Exposure occurs through an exposure pathway between the contaminant in the physical environment and the exposed person. (cdc.gov)

The tobacco etch virus (TEV) protease is widely used in in vitro and in vivo approaches for the removal of affinity tags from fusion proteins or the generation of proteins with a desired N-terminal amino acid. (bvsalud.org)
Whole genome sequencing across the tree of life has revealed the surprising observation that nine essential amino acid (EAA) biosynthesis pathways are missing from the metazoan lineage ( Payne and Loomis, 2006 ). (elifesciences.org)
Comparison of the structures of the new protein with those recently reported for N-acetyl-L-ornithine transcarbamylase indicates that amino acid residue 90 (B. fragilis numbering) plays an important role in conferring substrate specificity for N-succinyl-L-ornithine versus N-acetyl-L-ornithine. (nih.gov)
The underlying mechanism for rebalancing amino acid content for both o2 and RNAi is unclear, although it depends on reduced synthesis of the zein storage proteins and a compensatory increase in non-zein protein content [ 17 ]. (biomedcentral.com)
Carnitine is a naturally occurring hydrophilic amino acid derivative, produced endogenously in the kidneys and liver and derived from meat and dairy products in the diet. (medscape.com)
MutS has a conserved mismatch recognition domain characterized by GxFxE, or similar AMINO ACID MOTIFS that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. (bvsalud.org)

Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation or export) through the production of new proteins. (wikipedia.org)
Protein synthesis is a very similar process for both prokaryotes and eukaryotes but there are some distinct differences. (wikipedia.org)
Protein synthesis can be divided broadly into two phases-transcription and translation. (wikipedia.org)
Recent studies indicate that nutrient fluctuations and insulin resistance increase proinsulin synthesis in β cells beyond the capacity for folding of nascent polypeptides within the endoplasmic reticulum (ER) lumen, thereby disrupting ER homeostasis and triggering the unfolded protein response (UPR). (jci.org)
Take it after a workout when your protein synthesis is low to jump start muscle repair. (allstarhealth.com)
These three amino acids, along with glutamine, also promote protein synthesis and prevent muscle breakdown. (allstarhealth.com)
Fourteen years later, when Lipmann lectured in Lindau for the second time, his research focus had long shifted to the mechanisms of peptide and protein synthesis. (lindau-nobel.org)
In 1967, he put this group activation into perspective with new insights on the transcription and translation of the genetic code, admitting that „peptide synthesis as it were actually played only a featured part in protein synthesis", whose bigger picture called for more than just correct peptide bonds, namely for the correct sequence of amino acids as the necessary condition for the three-dimensional emergence of the correct function. (lindau-nobel.org)
In this review, we summarize the metabolic engineering strategies developed and employed for improving the de novo biosynthesis of sterols and steroids in yeast based on the regulation mechanisms, and introduce the recent progresses in de novo synthesis of some typical sterols and steroids in yeast. (springeropen.com)
The substantial reduction in synthesis of α-zeins results in smaller, less numerous protein bodies and a concomitant increase in non-zein endosperm proteins [ 3 ]. (biomedcentral.com)
Reduced synthesis of the lysine-poor zein proteins and compensatory increases in other proteins dramatically improves the nutritional quality of the grain. (biomedcentral.com)

We identify several previously described cases of genes originated de novo from noncoding genomic regions, supporting the idea that this mechanism frequently underlies the evolution of new protein-coding genes in mammals. (scentoferos.com)
Advances in synthetic biology and metabolic engineering have enabled de novo biosynthesis of sterols and steroids in yeast, which is a green and safe production route for these valuable steroidal compounds. (springeropen.com)
With rapid development of synthetic biology, de novo biosynthesis of steroids from simple carbon sources like glucose using engineered microbial cell factories has emerged as a promising alternative approach. (springeropen.com)
In the present review, we will focus on the regulatory principles and metabolic engineering strategies for improving the de novo production of sterols and steroids in yeast, and introduce the recent progresses in de novo biosynthesis of typical sterols and steroids. (springeropen.com)

Once correctly folded, the protein can undergo further maturation through different post-translational modifications. (wikipedia.org)
We previously showed that autophosphorylation occurs early during protein biosynthesis, hampering complete maturation of SADDAN receptors. (univr.it)
During elongation and maturation, the phagophore encapsulates damaged proteins and cell organelles. (hindawi.com)
During autophagosome maturation, cargo recruitment takes place through the recruitment of ATGs and LC3, and mature autophagosome formation occurs. (hindawi.com)

In "Archaeal lipids", it appears to play a functional role that we have not associated with any other gene, and it occurs in close proximity on the chromosome with another gene from the same subsystem. (theseed.org)
After the degradation of damaged proteins and lipids, amino acids and fatty acids are released into the cytoplasm and recycled for new biosynthesis of cellular components or energy production [ 4 ]. (hindawi.com)
RNA, lipids, and proteins. (who.int)

Lead toxicity symptoms arise are thought to occur by interfering with an essential enzyme delta-AminoLevulinic Acid Dehydratase , or ALAD. (wikidoc.org)
The enzyme is involved in biosynthesis of D-mycaminose. (genome.jp)
Here we examined the molecular mechanism by which multi-walled CNTs (MWCNTs) induce M1 polarization in vitro, with a focus on the induction of arachidonate 5-lipoxygenase (Alox5), a key enzyme in the biosynthesis of LMs. (cdc.gov)

Autophagy is a cellular catabolic process that eliminates damaged cell organelles, unfolded proteins, and various intracellular pathogens through lysosomal degradation. (hindawi.com)
In general, autophagy degrades long-lived damaged intracellular proteins, in contrast to the ubiquitin-proteasome system, which controls the degradation of short-lived proteins [ 2 ]. (hindawi.com)
The nutrient-dependent miRNA/mRNA balance controls 'seemingly futile' cycles of RNA-dependent protein biosynthesis and degradation (i.e., of nutrients to species-specific pheromones). (microrna.pro)
Under conditions of life that include nutrient-dependent / pheromone-controlled thermodynamics and thermoregulation, disordered protein degradation is not likely to be due to mutations (e.g., as commonly indicated). (microrna.pro)
Mutations perturb both the control and the regulation of protein biosynthesis and degradation. (microrna.pro)

During transcription, a section of DNA encoding a protein, known as a gene, is converted into a template molecule called messenger RNA (mRNA). (wikipedia.org)
S-Adenosylmethionine (SAM) is a naturally occurring molecule that functions as a methyl donor in many biochemical processes. (chemobiological.in)
A complementary RNA sequence that binds to a naturally occurring (sense) mRNA molecule, thus blocking its translation. (genomicglossaries.com)
MOCS1 gene mutations cause type A, MOCS2 gene mutations cause type B, and GPHN gene mutations cause type C. The proteins produced from each of these genes are involved in the formation (biosynthesis) of a molecule called molybdenum cofactor. (medlineplus.gov)

Interestingly, the character of charge transfer is quite different in proteins and in nucleic acids such as DNA 18 . (nature.com)
It seems that not until the technologies for working with nucleic acids and proteins are better integrated will their researchers be more connected than they are now. (genomicglossaries.com)

thus, PIGA mutations lead to a deficiency of GPI-anchored proteins, such as complement decay-accelerating factor (also known as CD55) and CD59 glycoprotein (CD59), which are both complement inhibitors. (medscape.com)
For more than 15 years he has been involved in discovery of inhibitors of bacterial cell-wall biosynthesis as potential antibacterial agents. (degruyter.com)

In this study, we combined transcript profiling and proteomic analysis to better understand which genes and proteins are altered by opaque2 in the W64A inbred line. (biomedcentral.com)
Serum concentrations of corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH) and corticosterone (CORT), expressions of genes and proteins for biosynthesis of hormones were lesser, which indicated an overall suppression of the hypothalamus-pituitary-adrenal (HPA) axis. (github.io)
Except for greater transcription of cyp19a1 in testes, transcriptions of genes and proteins for T and E2 biosynthesis along the HPG axis were lesser. (github.io)

This research systematically investigated effects of microcystin-LR (MC-LR) on endocrine organs, biosynthesis of hormones and positive/negative feedback of the endocrine system in rats. (github.io)
Transcripts of genes for biosynthesis of hormones and receptors along the HPT axis and expressions of proteins for biosynthesis of tetra-iodothyronine (T4) and tri-iodothyronine (T3) in thyroid were significantly altered. (github.io)
It was concluded that MCs caused an imbalance of positive and negative feedback of hormonal regulatory axes, blocked biosynthesis of key hormones and exhibited endocrine-disrupting effects. (github.io)
This data will allow for analysis of the selected steroid hormones and related binding protein that can be used to assist in disease diagnosis, treatment, and prevention of diseases, such as Polycystic Ovary Syndrome (PCOS), androgen deficiency, certain cancers, and hormone imbalances. (cdc.gov)

Major genomic deletions in independent eukaryotic lineages have led to repeated ancestral loss of biosynthesis pathways for nine of the twenty canonical amino acids. (elifesciences.org)
Previous studies have highlighted that EAA biosynthesis tends to be more energetically costly, raising the possibility that these pathways were lost from organisms with access to abundant EAAs. (elifesciences.org)
We designed codon-optimized biosynthesis pathways based on genes mined from Escherichia coli . (elifesciences.org)
The engulfment of a dying cell involves two parallel signal transduction pathways: theABC transporter CED-7 promotes cell-corpse recognition by the CED-1 transmembrane receptor, while the CED-2 Crk protein and the CED-10 Rac GTPase promote cytoskeletal reorganization and cell shape changes by the engulfing cell. (pdfdrugs.com)

DESCRIPTION Serine is among the many 20 naturally-occurring amino acids utilized by all organisms inside the biosynthesis of proteins. (chicken-genome.org)
Because alternative RNA splicing allows different types of mRNA molecules to be created from a single gene, it generates the diversity of protein function and structure that is essential to complex organisms. (genomicglossaries.com)
Instead, nutrient metabolism to pheromones controls nutrient-dependent reproduction and stabilizes intracellular signaling and the internuclear interactions of the genome to prevent the runaway selection for mutations in mutated organisms, which obviously never occurs. (microrna.pro)
I think he anticipated intuitive agreement (e.g., all organisms must eat and reproduce for natural selection to occur) rather than the statistical bastardization of his theory that followed. (microrna.pro)

Together, these results suggest that sleep-induced surge in ATP and the decrease in P-AMPK levels set the stage for increased anabolic processes during sleep and provide insight into the molecular events leading to the restorative biosynthetic processes occurring during sleep. (jneurosci.org)
For biosynthetic reactions to occur, it is therefore necessary to directly couple them with entropy-increasing reactions. (lindau-nobel.org)

Naturally occurring or "programmed" cell death is widespread during C. elegans development. (pdfdrugs.com)

This also may occur in patients with secondary carnitine deficiency as a consequence of ventricular tachycardia or fibrillation. (medscape.com)

The autophagophore membrane then elongates and encloses the molecules to be degraded forming an autophagosome, which occurs in two separate conjugation reactions catalyzed by autophagy-related proteins (ATGs). (hindawi.com)
There is growing evidence that the Dermal-Epidermal Junction (DEJ) and its proteins are a target of oxidative stress autophagy, matrix metalloproteinases, and senescence [6]. (heraldopenaccess.us)

Paula joined the Stanford faculty in 2013 where her current research program is focused on understanding the biosynthesis and physiological function of "molecular fossils" or biomarkers in extant bacteria. (stanford.edu)
Activity-based probes of cysteine proteases lead to non-native protein-protein contacts, which need to be resolved in order to be able to issue statements about physiological states and substrate binding. (bvsalud.org)
Thus, this chaperon protein can be an important player in physiological and pharmacological regulation of ASD features. (epiphanyasd.com)
Skin aging is a natural physiological process that occurs due to intrinsic and extrinsic factors. (heraldopenaccess.us)

These findings provide new information on the putative role of succinylated intermediates in arginine biosynthesis and on the evolution of transcarbamylases. (nih.gov)

A survey of agricultural technologies influencing the biosynthesis and accumulation of phenolic compounds in crop plants is presented, including observations on the effects of light, temperature, mineral nutrition, water management, grafting, elevated atmospheric CO 2 , growth and differentiation of the plant and application of elicitors, stimulating agents and plant activators. (mdpi.com)
These differences in protein abundance have given greater understanding of the mechanism by which salt stress promotes fatty acid accumulation in the un-sequenced microalga C. nivalis as it switches to a non-growth state, whereas C. reinhardtii does not have this response. (biomedcentral.com)
These analyses showed that the accumulation of some lysine-rich proteins, such as sorbitol dehydrogenase and glyceraldehyde3-phosphate dehydrogenase, was increased in mature kernels and may contribute substantially to the lysine content of opaque2 endosperm. (biomedcentral.com)
These changes in protein accumulation result in an endosperm that has nearly twice the lysine and tryptophan content of wild-type maize [ 3 ], which substantially improves its value for monogastric animals [ 9 ]. (biomedcentral.com)
In disorders of fatty acid oxidation, excessive lipid accumulation occurs in muscle, heart, and liver, with cardiac and skeletal myopathy and hepatomegaly. (medscape.com)

Previously, skin formulations were based on ascorbic acid, tocopherol, niacinamide, retinyl palmitate, anti-aging peptides, and proteins as topical solutions that reduce Reactive Oxygen Species (ROS) [3]. (heraldopenaccess.us)

Transcription occurs in the nucleus using DNA as a template to produce mRNA. (wikipedia.org)
Chronic ER stress promotes apoptosis, at least in part through the UPR-induced transcription factor C/EBP homologous protein (CHOP). (jci.org)
One of these genes, lin-35 , encodes a protein similar to the product of the human tumor suppressor gene Rb, and two other genes, dpl-1 and efl-1 , encode DP and E2F transcription factors, respectively. (pdfdrugs.com)
Many of these genes encode proteins similar to known transcription factors, and our studies indicate that the generation of cell diversity during development is in part regulated by a cascade of interacting transcription factors. (pdfdrugs.com)
The transcription of COX-1 yields a 2.7-kilobase (kb) messenger ribonucleic acid (mRNA) that encodes a 576-residue, 65-kd protein. (medscape.com)
Conversely, the transcription of COX-2 yields a 4.5-kb mRNA that encodes a 70-kd protein with roughly 70-75% homology to the COX-1 protein. (medscape.com)

A Bacteroides fragilis gene (argF'(bf)), the disruption of which renders the bacterium auxotrophic for arginine, was expressed and its recombinant protein purified and studied. (nih.gov)
Preterm newborns also may be at risk for developing carnitine deficiency because immature renal tubular function combined with impaired carnitine biosynthesis renders them strictly dependent on exogenous supplies to maintain normal plasma carnitine levels. (medscape.com)

Protein biosynthesis has a key role in disease as changes and errors in this process, through underlying DNA mutations or protein misfolding, are often the underlying causes of a disease. (wikipedia.org)
Clinical manifestations of PNH occur when a HSC clone carrying somatic PIGA mutations acquires a growth advantage and differentiates, generating mature blood cells that are deficient of GPI-anchored proteins. (medscape.com)
Mutations in the MOCS1 , MOCS2 , or GPHN gene reduce or eliminate the function of the associated protein, which impairs molybdenum cofactor biosynthesis. (medlineplus.gov)

Saccharomyces cerevisiae has been extensively employed as the chassis organism for steroids biosynthesis since it is generally regarded as safe (GRAS) feature, well-studied genetic background and readily available manipulation tools. (springeropen.com)
It is derived from progesterone via 17α-hydroxylase and is a chemical intermediate in the biosynthesis of several other steroids, including cortisol. (cdc.gov)

The levels of phosphorylated AMP-activated protein kinase (P-AMPK), well known for its role in cellular energy sensing and regulation, and ATP show reciprocal changes. (jneurosci.org)
Despite the importance of the precise fluctuations of JH levels during insect development, the molecular mechanisms underlying the regulation of JH biosynthesis remain poorly understood. (nature.com)

There were abundance differences in proteins associated with stress, photosynthesis, carbohydrate and lipid metabolism proteins. (biomedcentral.com)

Moreover, PRIN2 and CSP41b form a distinct protein complex in vitro that binds DNA. (frontiersin.org)
Taken together, our results suggest that PEP activity and consequently the switch from NEP to PEP activity, is essential during embryo development and that the PRIN2-CSP41b DNA binding protein complex possibly is important for full PEP activity during this process. (frontiersin.org)
BodyStrong's Amino Complex contains 17 different amino acids from hydrolyzed protein. (allstarhealth.com)
BodyStrong's Amino Complex provides a full spectrum 1,500 mg array of essential and non-essential amino acids derived from hydrolyzed protein. (allstarhealth.com)
In the presence of sufficient nutrients, activation of mTOR inhibits the ULK1 complex, whereas, under conditions of nutrient starvation, AMPK inhibits mTOR and activates the ULK1 and PI3KC3 complex leading to initiation of phagophore biosynthesis. (hindawi.com)
First, phagophore formation requires cytoplasmic vesicle nucleation, which occurs when the ATG1/ULK1 complex, which is comprised of ULK1, FIP200, ATG13, and ATG101, interacts with the Class III PI3K complex. (hindawi.com)
Hence, the commentary highlights the significance of dermal-epidermal junction proteins, specifically collagen IV, a target of a newly developed complex DL-linefade. (heraldopenaccess.us)
The interconnecting complex meshwork of DEJ proteins and the finger-like rete ridges aid in maintaining the skin's structural integrity and mechanical stability. (heraldopenaccess.us)

Post-translational modifications can alter the protein's ability to function, where it is located within the cell (e.g. cytoplasm or nucleus) and the protein's ability to interact with other proteins. (wikipedia.org)
Besides, proteins BdDOF24 and BdGAMYB interact in yeast-2 hybrid systems and in plant nuclei, and in transient expression assays in aleurone layers BdDOF24 is a transcriptional repressor and BdGAMYB is an activator of the BdCathB promoter, as occurs with the puta-tive orthologous in barley BPBF-HvDOF24 and HvGAMYB. (upm.es)
These include lead's ability to inhibit or mimic the actions of calcium (which can affect calcium-dependent or related processes) and to interact with proteins (including those with sulfhydryl, amine, phosphate, and carboxyl groups) [ATSDR 2010]. (cdc.gov)

These findings suggest that CHOP is a fundamental factor that links protein misfolding in the ER to oxidative stress and apoptosis in β cells under conditions of increased insulin demand. (jci.org)

Furthermore, the changes in ATP exhibit reciprocity with the phosphorylated state of the cellular energy sensor, phosphorylated AMP-activated protein kinase (P-AMPK), thus supporting the induction of anabolic processes during sleep. (jneurosci.org)
Protein post-translational modifications (PTMs) take many shapes, have many effects and are necessary for cellular homeostasis. (biologists.com)

Programmed cell death appears to be initiated by the transcriptional activation of egl-1 , the protein product of which binds the mitochondrial protein CED-9 and causes the release of CED-4 from CED-9 and the translocation of CED-4from the mitochondrial to the nuclear membrane. (pdfdrugs.com)

The mature mRNA is exported from the cell nucleus via nuclear pores to the cytoplasm of the cell for translation to occur. (wikipedia.org)

In biological systems, charge transfer figures in various key processes, from energy transduction to CO 2 reduction and water splitting, to nucleic acid biosynthesis. (nature.com)
Abnormal increases in cell wall plasticity, biosynthesis of proteins, and production of ethylene occur in plant tissues following exposure, and these processes are responsible for uncontrolled cell division. (ac.ir)

It enhances the performance of niacinamide-based skin formulations by acting synergistically and inducing collagen IV biosynthesis. (heraldopenaccess.us)
These zones are mainly composed of collagen IV, plectin, laminin (proteins of BM), and nidogen in the upper regions, collagen IV, VI, anchoring fibrils, and heparan sulfate proteoglycan (proteins of LD) [8]. (heraldopenaccess.us)
Collagen IV is a known significant anchoring protein found in the lamina densa region of the DEJ that provides a framework to the interconnecting network of dermis-epidermis. (heraldopenaccess.us)
Although these products help treat skin issues, niacinamide usually targets the collagen I and III proteins of the inner dermal layer of the skin that causes skin aging [9]. (heraldopenaccess.us)
Collagen IV in the DEJ gets depleted as the non-photodamaged skin aging occurs chronologically [8]. (heraldopenaccess.us)

However, the exact mechanisms by which it improves protein quality and creates a soft endosperm texture are unclear. (biomedcentral.com)

Thus, it is now thought that all eukaryotes contain an organelle related to mitochondria, and its most conserved function is in Fe/S protein biogenesis, not ATP production. (ncl.ac.uk)
However, the physiologic significance of prostaglandin production did not unfold until 1971, when Vane, Smith, and Willis discovered that aspirin and indomethacin inhibited prostaglandin biosynthesis. (medscape.com)

They provide structural evidence that this protein is a novel N-succinyl-L-ornithine transcarbamylase. (nih.gov)

ALAD is a zinc-binding protein which is important in the biosynthesis of heme , the co-factor found in hemoglobin . (wikidoc.org)

The process of activation and catalytic turnover of DUB Cezanne-1 is a multistage cycle with several critical dynamic transitions that cannot be characterized based on protein structures alone. (bvsalud.org)

They have been defined as monotropic integral membrane proteins located primarily in the endoplasmic reticulum (COX-1) and the perinuclear envelope (COX-2). (medscape.com)

Maize protein is deficient in the essential amino acids lysine and tryptophan, which limits its value for monogastric animals. (biomedcentral.com)

DNA repair proteins that include the bacterial MutS DNA mismatch-binding protein and its eukaryotic homologs that function in DNA MISMATCH REPAIR and recombination of DNA during MEIOSIS. (bvsalud.org)

BASF has provided data on the identity of rice line PWC16, a detailed description of the modification method and breeding history, information on the modified gene, the resulting protein and its mode of action and the stability of trait expression. (canada.ca)

The discovery of a tiny mitochondrion in microsporidia (Figures 1 and 2) was an important piece of evidence that led to current ideas that the mitochondrial endosymbiosis occurred at the origin of eukaryotes. (ncl.ac.uk)

Increases in seed was done through self pollination, or natural pollination occurring within the variety. (canada.ca)

More than half of all human genes are alternatively spliced, so it is expected that alternative pre- mRNA splicing will be responsible for the identification of more than 90 percent of all human proteins. (genomicglossaries.com)
Highly specific and effective gene silencing of any disease can be achieved by an accurate knowledge of the target mRNA sequence and rational design of its complementary antisense agents for the downregulation of its protein message. (genomicglossaries.com)
Treatment of J774A.1 murine macrophages with MWCNTs increased the expression of Alox5 mRNA in a concentration- and time-dependent manner, with the largest induction (5.3-fold over control) occurring at 10 mg/ml and 3 days post-exposure. (cdc.gov)

We have assigned the function "Hydroxymethylglutaryl-CoA reductase (EC 1.1.1.34)" to the encoded protein. (theseed.org)

the next seven years showing that the mitosome functions in the biosynthesis of essential cytosolic and nuclear Iron/Sulphur (Fe/S) proteins . (ncl.ac.uk)

Transformation of ESR into the cell stress augments reception in the domain responsible for binding the endo- and exogenous ligands of sigma 1 receptor chaperon protein (Sigma1R) [1] responsible for adaptive reactions [8]. (epiphanyasd.com)

One of these PTMs, Nε-lysine acetylation, was thought to occur only in the mitochondria, cytosol and nucleus, but this paradigm was challenged in the past decade with the discovery of lysine acetylation in the lumen of the endoplasmic reticulum (ER). (biologists.com)

JH biosynthesis involves a series of enzymatic reactions that are conventionally organized into two modules. (nature.com)
Discontinue use and consult your doctor if any adverse reactions occur. (allstarhealth.com)

No matter how toxic, no chemical can harm a person (child, adult, or both) unless exposure occurs . (cdc.gov)

In order for a cell to respond to changes in internal and external environmental factors, a broad range of protein co- and post-translational modifications have evolved to expand upon the relatively static properties encoded in protein side-chains. (biologists.com)
The method of single-cell analysis is being used to find out which DNA segments become active for the protein biosynthesis of a cell. (tum.de)
When a protein for cell assembly is generated, only certain segments of a person's DNA are read and translated into RNA which serves as a basis for protein biosynthesis. (tum.de)

Processing of fusion proteins by the TEV protease can either be achieved by encoding the TEV protease and its recognition site on one construct (self-cleavage) or on two different constructs (co-expression). (bvsalud.org)
The mutant also had altered expression of a number of starch biosynthesis genes and this was associated with a more highly crystalline starch. (biomedcentral.com)

Biologic uptake: the process by which the transfer of substances from the environment to plants, animals, and humans occurs. (cdc.gov)

We show here that PLASTID REDOX INSENSITIVE 2 (PRIN2) and CHLOROPLAST STEM-LOOP BINDING PROTEIN 41 kDa (CSP41b), two proteins identified in plastid nucleoid preparations, are essential for proper plant embryo development. (frontiersin.org)
Amino Acids, the building blocks of protein, are essential for muscle growth, maintenance and repair. (allstarhealth.com)

Anatomy16

Organisms10

Chemicals and Drugs149

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes56

Disciplines and Occupations1

Technology, Industry, Agriculture2

Information Science5

Health Care1

Enzymes8

Heme biosynthesis1

Metabolic pathways2

Pathway6

Amino acid6

Synthesis11

Novo4

Maturation4

Lipids3

Enzyme3

Degradation5

Molecule4

Nucleic acids2

Inhibitors2

Genes and proteins3

Hormones4

Pathways4

Organisms4

Biosynthetic2

Naturally1

Secondary1

Autophagy2

Physiological4

Intermediates1

Accumulation5

Peptides1

Transcription6

Renders2

Mutations3

Steroids2

Regulation2

Metabolism1

Complex8

Interact3

Oxidative stress1

Cellular2

Binds1

Cytoplasm1

Processes2

Collagen5

Mechanisms1

Production2

Structural1

Hemoglobin1

Structures1

Membrane1

Deficient1

Bacterial1

Stability1

Mitochondrial1

Increases1

MRNA3

Function1

Nuclear1

Exogenous1

Thought to occur1

Reactions2

Adult1

Cell3

Expression2

Substances1

Essential2