• However, a monovalent serogroup A meningococcal conjugate vaccine (MenAfriVac) was introduced in the region in 2010. (wikipedia.org)
  • The Meningitis Vaccine Project was conceived in 2001 as an effort to stop the spread of meningitis in this region. (wikipedia.org)
  • Meningococcal vaccine availability differs by North American country. (medpagetoday.com)
  • Before a vaccine was available, Hib disease was the most common cause of meningitis in children under the age of five, and often led to pneumonia, skin infections, hearing loss, permanent brain injury or death. (texas.gov)
  • MenHibrix, a combination vaccine, is a 4-dose sequence approved for use in children as young as 6 weeks old and is indicated for active immunity against invasive disease caused by Neisseria meningitides serogroups C and Y, and Haemophilus influenzae type b. (medscape.com)
  • In October 2014, the FDA approved the first meningococcal vaccine for serogroup B (Trumenba) under the breakthrough therapy designation and accelerated approval regulatory pathways. (medscape.com)
  • Among the 29 meningococcal disease cases among persons with HIV in 2022, 22 had not received MenACWY vaccine, six had unknown MenACWY vaccination history, and one had received MenACWY vaccine, but the number of doses received was unknown. (medscape.com)
  • Three hundred thirty thousand doses of bivalent A/C meningococcal vaccine were given, achieving approximately 65% coverage of the target population. (cdc.gov)
  • Because of the risk of meningococcal disease among hikers, CDC recommends that tourists planning to hike in Nepal receive meningococcal vaccine. (cdc.gov)
  • Although all cases of meningococcal disease to date have occurred in hikers, it is prudent for other travelers to Nepal to receive the vaccine also. (cdc.gov)
  • The serogroup A meningococcal vaccine has a clinical efficacy of 85%-95% for at least 1 year, with protection achieved 1-2 weeks after vaccination. (cdc.gov)
  • The Hib vaccine has been very effective in reducing the rate of childhood meningitis. (weber.edu)
  • The pneumococcal vaccine works against the strain of bacteria causing meningitis primarily in elderly people. (weber.edu)
  • The vaccine currently in use is a Meningococcal Polysaccharides, Immunity after one vaccination lasts for three years. (gov.tw)
  • Serogroup A Neisseria meningitidis was the major cause of meningococcal meningitis epidemics in the African meningitis belt before 2010 when the monovalent meningococcal A conjugate vaccine (MenAfriVac) was introduced in the region. (springer.com)
  • This study showed the emergence of serogroup X, a non-vaccine type, as the predominant N. meningitidis serogroup in the wake of a declining serogroup W in Ghana's meningitis belt. (springer.com)
  • Beginning in 2010, in an effort to reduce the number of cases of meningococcus, a newly developed meningococcal A conjugate vaccine, known as MenAfriVac, was introduced to countries in the Meningitis Belt. (chop.edu)
  • This vaccine represents an affordable way to protect the millions of people at risk during the deadly group A meningococcal epidemics. (chop.edu)
  • On July 28, 2014, the American Academy of Pediatrics (AAP) updated recommendations for the administration of the meningococcal vaccine in children. (pharmacytimes.com)
  • This vaccine helps reduce the risk of developing Neisseria meningitidis infection, which may lead to diverse complications including meningitis, bacteremia, and pneumonia. (pharmacytimes.com)
  • 4 Despite the fact that serogroup B meningitis affects children disproportionately, currently, no vaccine is available in the United States that protects patients against serogroup B, which may be why the meningococcal vaccine is only recommended in selected groups of very young children. (pharmacytimes.com)
  • All formulations of the meningococcal vaccine are conjugated polysaccharide vaccines, with the exception of Menomune, which is a polysaccharide vaccine. (pharmacytimes.com)
  • Because conjugated vaccines stimulate a T-cell response, conjugated vaccines induce a more robust immune response and better immunologic memory than the polysaccharide-only meningococcal vaccine (Menomune), which does not stimulate a T-cell response. (pharmacytimes.com)
  • Unless use of the meningococcal conjugate vaccine is contraindicated, for pediatric patients, meningococcal conjugate vaccines (ie, Menveo, Menactra, or MenHibrix) are preferred over the meningococcal polysaccharide vaccine (ie, Menomune). (pharmacytimes.com)
  • Most infants should not receive the meningococcal vaccine. (pharmacytimes.com)
  • For most pediatric patients, the first meningococcal vaccine is administered between 11 and 15 years of age. (pharmacytimes.com)
  • Because the next dose is typically administered 16 years of age, it is important to remember that subsequent doses of the meningococcal vaccine must be administered at least 8 weeks apart. (pharmacytimes.com)
  • A variety of routine childhood and adolescent meningococcal vaccination programs using monovalent (serogroup C) and quadrivalent (A, C, Y, W) conjugate vaccines have been implemented in Canada since 2002, resulting in a decrease in invasive meningococcal disease (IMD) incidence, particularly in serogroup C. Meningococcal vaccines have also been used for outbreak response, including the multicomponent vaccine serogroup B vaccine. (canada.ca)
  • Invasive meningococcal disease caused by some serogroups is vaccine preventable and endemic in Canada, with increased activity occurring periodically in the winter months. (canada.ca)
  • This has resulted in a decrease in IMD incidence, particularly for serogroup C. In the last decade, the multicomponent meningococcal B vaccine (4CMenB) has been used to control outbreaks Footnote 3 but has not been used in routine vaccination programs across the country. (canada.ca)
  • In 2010, a new meningococcal conjugate vaccine (Menveo) was licensed for use in the United States for 11-55 year-olds and has demonstrated non-inferiority to MCV4 (Menactra). (mn.us)
  • Menactra was licensed for use in the United States in January 2005 for persons aged 11 to 55 years, and was the first meningococcal polysaccharide-protein conjugate vaccine for serogroups A,C,Y, and W-135 (MCV4). (mn.us)
  • A meningitis vaccine is only recommended for children 2 months to 10 years old identified as having an increased risk of meningitis infection. (chicagotribune.com)
  • Bexsero is a vaccine used to protect individuals from the age of two months against invasive meningococcal disease caused by one group of the bacterium Neisseria meningitidis (group B). Invasive disease occurs when the bacteria spread through the body causing serious infections such as meningitis (infection of the membranes that surround the brain and spine) and septicaemia (blood infection). (europa.eu)
  • The FDA has approved the first U.S. vaccine against invasive meningococcal disease caused by Neisseria meningitides serogroup B. Trumenba is approved for use in individuals aged 10 through 25 years. (medscape.com)
  • Approval was based on three randomized studies in about 2800 adolescents, in which 82% of subjects given three doses of the vaccine developed antibodies against four different N meningitidis serogroup B strains representative of those that cause serogroup B meningococcal disease in the United States, compared with less than 1% prior to vaccination. (medscape.com)
  • Since the introduction of MenAfrivac vaccine in 2010, there has been a dramatic decrease in NmA cases while other pathogen species and Nm variants including NmW, NmC and Streptococcus pneumoniae have become more prevalent reflecting a greater diversity of bacterial strains causing meningitis epidemics in Africa today. (biomedcentral.com)
  • The most common meningococcal vaccine series usually starts at the age of 11 years. (smh.com)
  • Another meningococcal vaccine is recommended for teenagers and young adults aged 16-23 years, especially if they fall into a high-risk category. (smh.com)
  • There is also a MenB vaccine that addresses different forms of meningitis. (awayclinic.com)
  • Meningococcal polysaccharide vaccine ( MPSV4 ) has been available since the 1970s. (medthical.com)
  • It is the only meningococcal vaccine licensed for those older than 55 years old. (medthical.com)
  • Children between 2 months- 10 years : Meningococcal conjugate vaccine (MenACWY or Hib-MenCY-TT) is recommended for those who are at increased risk for meningococcal disease. (medthical.com)
  • The MenACWY vaccine was introduced in the UK in August 2015 to protect teenagers against a harmful strain of meningococcal W (MenW) disease which had been rapidly rising since 2009. (meningitis.org)
  • MenACWY vaccine directly protects vaccinated people from four different strains of meningococcal meningitis and septicaemia (groups A, C, W & Y) and also stops them from carrying the bacteria in the back of the nose and throat. (meningitis.org)
  • Routine meningococcal vaccine programs in Canada differ by province and territory. (gc.ca)
  • The CDC recommends all children receive their first dose of meningococcal serogroup A, C, Y and W-135 conjugate vaccine at age 11-12 and an additional booster dose at age 16. (nvic.org)
  • The booster dose recommendation was made in 2010 after studies noted that only 50 percent of adolescents vaccinated at age 11-12 had sufficient vaccine-acquired antibodies to protect them against meningococcal disease five years post-vaccination. (nvic.org)
  • The committee came to this conclusion after evaluating multiple factors including the high number of people that would require vaccination in order to prevent a single case of meningococcal disease, the low rates of the disease, the vaccine's cost, lack of efficacy and safety data as well as the potential risk that serious adverse reactions would exceed the number of cases potentially prevented from the vaccine. (nvic.org)
  • In 2020 for meningococcal cases, 85.7 percent of college students (18-24 years) and 69.2 percent of person not attending college (18-24 years) had received at least one dose of MenACWY vaccine. (nvic.org)
  • As of November 24, 2023, there have been 46,228 reports of meningococcal vaccine reactions, hospitalizations, injuries and deaths following meningococcal vaccinations made to the federal Vaccine Adverse Events Reporting System (VAERS), including 265 related deaths, 4,922 hospitalizations, and 606 related disabilities. (nvic.org)
  • As of December 1, 2023 , there had been 135 claims filed in the federal Vaccine Injury Compensation Program (VICP) for injuries and deaths following meningococcal vaccination, including 3 deaths and 132 serious injuries. (nvic.org)
  • Meningococcal B (MenB) vaccine is the new kid on the block for children and adolescents, having won approval in 2014. (texmed.org)
  • This vaccine for meningitis B often is confused with the older meningococcal vaccine. (texmed.org)
  • 1 Serogroup C vaccine is the only meningococcal vaccine routinely offered to all children in Australia under the National Immunization Programme. (who.int)
  • The national meningococcal C vaccination programme, introduced in Australia in January 2003, comprises ongoing inclusion of the vaccine in the National Immunization Programme schedule at one year of age, as well as a catch-up programme until 2006 for children aged 2-19 years. (who.int)
  • Two types of vaccines can protect against several kinds of meningococcal disease: meningococcal conjugate vaccine (protect against serogroups A, C, W, and Y) and meningococcal B vaccine (protect against serogroup B). (wa.gov)
  • Meningococcal conjugate vaccine is recommended for all children aged 11 to 12 years, with a booster shot for teens at 16 years of age. (wa.gov)
  • Travelers to certain countries, and anyone aged 2 months and older who are at increased risk for meningococcal disease should also get the vaccine. (wa.gov)
  • People who stay at increased risk for meningococcal disease should get revaccinated every 5 years with meningococcal conjugate vaccine as long as they remain at increased risk. (wa.gov)
  • Some people should get meningococcal B vaccine if they are 10 years of age and older with certain health conditions, taking certain medications, are at increased risk because of a meningococcal B disease outbreak, or work with meningococcal bacterial in a lab. (wa.gov)
  • Increasing the inclusion of meningococcal vaccines into the NIPs [national immunization programs] of North American countries beyond the US, Canada, and Cuba, is an important milestone that should remain a focus of public health authorities. (medpagetoday.com)
  • Meningococcal vaccines have helped to both reduce IMD rates among vaccinated individuals and provide some herd immunity against A, C, W, and Y (but not B) serogroups. (medpagetoday.com)
  • In the United States, multiple meningococcal serogroup A, C, W, and Y (MenACWY) conjugate vaccines as well as meningitis serogroup B vaccines are licensed. (medpagetoday.com)
  • The US Advisory Committee on Immunization Practices recommends routine MenACWY vaccination to adolescents and meningitis serogroup B (MenB) vaccines to certain high-risk groups. (medpagetoday.com)
  • Currently there are safe and effective vaccines against meningococcal disease caused by serogroups A, C, W135, and Y. Meningococcal vaccines are recommended for all 11 to 12 year olds, with a booster at 16. (cdc.gov)
  • Marc Merlin] Besides vaccines, are there things people can do to protect themselves from getting meningitis? (cdc.gov)
  • Leonard Mayer] Vaccines are the best strategy to prevent meningococcal disease. (cdc.gov)
  • As scientists advance in their understanding of meningitis, they have developed several vaccines that offer protection against the disease. (medicalnewstoday.com)
  • Examples include the meningococcal, Haemophilus influenzae type B (Hib), and pneumococcal vaccines. (medicalnewstoday.com)
  • In areas where vaccines are not available, the mumps virus is responsible for 10-20% of viral meningitis cases. (medicalnewstoday.com)
  • given the recent increase in meningococcal disease cases in this population, health care providers should ensure that all persons with HIV are up to date with MenACWY vaccination per ACIP recommendations, as well as other vaccines recommended for this population. (medscape.com)
  • Meningococcal polysaccharide vaccines have been used to control epidemics in the past (4-6). (cdc.gov)
  • 6. There are vaccines against many of the strains of bacteria that cause meningitis. (weber.edu)
  • Since the early 2000s, a variety of routine childhood and adolescent vaccination programs using monovalent (serogroup C) and quadravalent (serogroup A, C, Y and W-135) meningococcal conjugate vaccines have been implemented in Canada Footnote 3 . (canada.ca)
  • We are fortunate, especially in the UK, that vaccines for illnesses such as meningitis are readily available, and are often free of charge. (laboratorytalk.com)
  • The two new vaccines, MenACWY-CRM and 4CMenB, discovered by the University of Southampton (UOS) and manufactured by drugs firm Novartis, actively prevent the transmission of meningitis bacteria from one person to another. (laboratorytalk.com)
  • There are two vaccines available, they can prevent 4 types of meningococcal disease including the common serogroups B,C and Y. (medthical.com)
  • You must receive meningococcal vaccines at least 2 weeks before your first dose of ULTOMIRIS if you are not vaccinated. (biospace.com)
  • There are five FDA approved meningococcal vaccines available for use in the U.S. that target a total of 5 of the 13 serotypes of meningococcal disease. (nvic.org)
  • Three vaccines, Menectra (Sanofi Pasteur), Menveo (Novartis/GlaxoSmithKline), and MenQuadfi (Sanofi Pasteur) are conjugate vaccines that target serogroups A, C, Y and W-135 meningococcal bacteria and two vaccines, BEXSERO (Novartis/GlaxoSmithKline) and TRUMENBA (Wyeth/Pfizer) are recombinant vaccines that target serogroup B meningococcal bacteria. (nvic.org)
  • Meningococcal septicemia, which is characterized by rapid circulatory collapse and a hemorrhagic rash, is a more severe, but less common, form of meningococcal disease. (medscape.com)
  • In this case, the patient showed the effects of a meningococcal septicemia due to the petechial rash present on examination. (weber.edu)
  • Meningococcal disease-meningococcal meningitis or meningococcal septicemia, which are the two forms of this disease-are diseases that reappear from time to time. (smh.com)
  • They are a sign of blood poisoning (septicemia), which sometimes happens with meningitis, particularly the meningococcal strain. (lisd.net)
  • This bacterium can cause serious and sometimes fatal diseases including meningitis (infection of the brain lining) and meningococcal septicemia (infection of the blood). (gc.ca)
  • Most frequently, the illness can result in inflammation of the meninges of the brain (meningitis) and a serious bloodstream infection (septicemia/meningococcemia). (nvic.org)
  • It usually causes two types of infections: swelling of the covering of the brain and spinal cord (meningitis) and blood infections (septicemia). (wa.gov)
  • Meningococcal septicemia (bloodstream infection) is the second most common type of meningococcal infection (40 percent of cases). (wa.gov)
  • Canada and Cuba are the only other North American countries that recommend routine meningitis vaccination. (medpagetoday.com)
  • The incidence of Hib meningitis decreases after the age of 2 months due to vaccination. (medicalnewstoday.com)
  • Vaccination is used for close contacts of patients with meningococcal disease due to A, C, Y, or W135 serogroups, to prevent secondary cases. (medscape.com)
  • Quadrivalent meningococcal conjugate vaccination (MenACWY) is routinely recommended for adolescents and persons at increased risk for meningococcal disease, [ 1 ] including those with HIV. (medscape.com)
  • A dramatic decline in the number of meningitis cases occurred coincident with the initiation of the mass vaccination campaign. (cdc.gov)
  • Fever of short duration and slight swelling at the site of vaccination may occur within 24 hours after vaccination. (gov.tw)
  • Learn what the latest guidelines from the American Academy of Pediatrics recommend for meningococcal vaccination among children, adolescents, and young adults. (pharmacytimes.com)
  • Vaccination is also available to protect against certain types of meningitis, and it is recommended for certain groups such as college students living in dormitories. (awayclinic.com)
  • Preventative measures such as vaccination, good hygiene practices like regular handwashing and avoiding sharing drinks, cigarettes, or personal items with others can help to prevent the spread of meningitis. (awayclinic.com)
  • If your doctor decided that urgent treatment with ULTOMIRIS is needed, you should receive meningococcal vaccination as soon as possible. (biospace.com)
  • Following introduction of a childhood vaccination programme against meningococcal type C in 2003, notification rates in all age groups decreased, but the proportion of IMD notifications in people aged 65 years and over rose significantly (from 4% to 6%, P = 0.01). (who.int)
  • Epidemics occur throughout Africa in the dry season, coincide with periods of very low humidity and dusty conditions, and disappear with the onset of the rains, suggesting that these environmental factors may also play an important role in the occurrence of the disease ( 1 - 3 ). (cdc.gov)
  • Experts at the Centers for Disease Control and Prevention (CDC) today launched a campaign to educate parents about one of the things they can do to protect their children at 11 and 12 years of age and for years to come: make sure they are vaccinated against serious, sometimes life-threatening diseases such as meningitis, tetanus, diphtheria, whooping cough, and cervical cancer. (cdc.gov)
  • Lapeyssonnie noticed that the disease occurred in areas receiving 300-1,100 mm of mean annual rainfall, which is the case in sub-Saharan Africa. (wikipedia.org)
  • Meningococcal disease is persistently high in this region. (wikipedia.org)
  • Other factors contributing to the sustained transmission of meningococcal disease include dust, other respiratory viruses that co-circulate, as well as close social contact. (wikipedia.org)
  • At its peak, the incidence of meningococcal disease has reached rates of up to 1,000 cases per 100,000 inhabitants, such as during the epidemics of 1996 and 2000-2001. (wikipedia.org)
  • Despite a declining incidence of invasive meningococcal disease (IMD) in many areas of North America, ongoing challenges to prevention efforts exist, according to an update from the Global Meningococcal Initiative. (medpagetoday.com)
  • Marc Merlin] Hi, I'm Marc Merlin and today I'm talking with Dr. Leonard Mayer, a public health microbiologist specializing in meningococcal disease at CDC. (cdc.gov)
  • Our conversation is based on a study about invasive meningococcal capsular group Y disease in England and Wales, which appears in CDC's journal, Emerging Infectious Diseases . (cdc.gov)
  • Marc Merlin] Dr. Mayer, what is meningococcal disease? (cdc.gov)
  • Such invasive meningococcal disease is a serious, life-threatening illness requiring prompt medical treatment. (cdc.gov)
  • Other types of meningococcal disease, such as pneumonia, can also occur. (cdc.gov)
  • Of the 12 known capsule serogroups, A, B, C, W135, and Y -- plus sometimes X -- are the main ones which cause meningococcal disease. (cdc.gov)
  • Over the past 10 to 20 years, the proportion of meningococcal disease caused by Men Y has changed in several countries, including the United States, and from this study, the United Kingdom, too. (cdc.gov)
  • It was designed to monitor any changes in the number of cases of meningococcal disease, changes in the syndrome or type of disease, changes in the age group affected, and changes in the bacteria causing disease. (cdc.gov)
  • Leonard Mayer] Comparing 2007 to 2009, there was a slight decrease in the number of cases of meningococcal disease, but the proportion caused by Men Y doubled. (cdc.gov)
  • Leonard Mayer] Meningococcal disease in the US is rare, with about 1,000 cases reported each year. (cdc.gov)
  • The clone that increased the most in the UK study during the study time period is similar to the one causing about one third of all meningococcal disease in the US over the past several years. (cdc.gov)
  • Meningococcal disease can be fatal in 10 to 15percent of cases and result in long-term disabilities in 15 percent of survivors. (cdc.gov)
  • If someone you've been in close contact with gets meningococcal disease, your doctor or health department may recommend antibiotics to prevent you from getting infected. (cdc.gov)
  • The type of pathogen that causes meningitis influences its symptoms and the severity of the disease. (medicalnewstoday.com)
  • According to the Centers for Disease Control and Prevention (CDC) , non- polio enteroviruses are the leading cause of viral meningitis in the United States. (medicalnewstoday.com)
  • Studies show a higher rate of fungal meningitis in children with a hematological disease such as leukemia or children who have undergone a hematopoietic stem cell or solid organ transplant . (medicalnewstoday.com)
  • This can cause a delay in meningitis diagnosis and allow the disease to become more serious. (medicalnewstoday.com)
  • Meningococcal disease is potentially fatal and always should be viewed as a medical emergency. (medscape.com)
  • Recent outbreaks of serogroup B meningococcal disease on a few college campuses have heightened concerns for this potentially deadly disease. (medscape.com)
  • [ 2 ] This report describes an increase in meningococcal disease among persons with HIV in the United States in 2022. (medscape.com)
  • Meningococcal disease cases are reported through the National Notifiable Diseases Surveillance System, with additional epidemiologic information and isolates obtained through Enhanced Meningococcal Disease Surveillance. (medscape.com)
  • During 2017-2021, five to 15 meningococcal disease cases were reported each year among persons with HIV, representing 1.5%-4.3% of all meningococcal disease cases annually (Figure). (medscape.com)
  • Based on preliminary data, 29 meningococcal disease cases have been reported among persons with HIV in 2022, accounting for 9.8% of all cases. (medscape.com)
  • however, after excluding MSM outbreak-associated cases for all years, a substantial increase in meningococcal disease cases among persons with HIV in 2022 remained (i.e., 14 cases compared with four to eight cases per year during 2017-2021) (Figure). (medscape.com)
  • Health care providers should also maintain a high index of suspicion for meningococcal disease among persons with HIV who have symptoms of meningococcal disease. (medscape.com)
  • [ 3 ] Providers should ensure that patients with meningococcal disease and unknown HIV status are screened for HIV. (medscape.com)
  • However, meningococcal disease among hikers is now being recognized. (cdc.gov)
  • Between January 1984 and January 1985, two culture-confirmed and four clinically suspected cases of meningococcal disease have been documented among tourists from western countries traveling in Nepal. (cdc.gov)
  • Editorial Note: Epidemic meningococcal disease has not been reported previously in Nepal, and, except for Mongolia and Vietnam, has been reported in no other Asian country (1,2). (cdc.gov)
  • Large epidemics of group A meningococcal disease have occurred primarily in the 'meningitis belt' of Africa, which consists of the semiarid Sahelian zone south of the Sahara (3). (cdc.gov)
  • By comparison, the annual incidence of meningococcal disease in this age group in the United States is approximately 0.3/100,000 (7). (cdc.gov)
  • As the disease progresses, patients of any age may have seizures' (CDC Meningococcal Disease). (weber.edu)
  • Since meningitis is a reportable, communicable disease, the medical teams must promptly notify state and county public health officials. (weber.edu)
  • Meningococcal meningitis is an acute infectious bacterial disease. (gov.tw)
  • Meningococcal disease is found worldwide but epidemics may occur within this country, particularly during the dry season. (fitfortravel.nhs.uk)
  • Large epidemics of the disease due to meningococci have spread during the last decade throughout a large area of Africa's 'meningitis belt' and outside [ 1 ]. (springer.com)
  • Cerebrospinal meningitis (CSM) caused by N. meningitidis is a contagious disease. (springer.com)
  • However, other countries, specially those neighbouring the belt are also reporting meningococcal disease. (who.int)
  • Invasive meningococcal disease is a rare but severe infection in Canada that mostly affects the very young. (canada.ca)
  • National enhanced case-based surveillance has been conducted in Canada since 1995 through the Public Health Agency of Canada's Enhanced Invasive Meningococcal Disease Surveillance System (eIMDSS). (canada.ca)
  • There is perennial interest in invasive meningococcal disease (IMD) from a public health and general community perspective. (health.gov.au)
  • Single organ disease such as arthritis occurs less frequently. (health.gov.au)
  • The bacterial form of this disease is associated with hearing loss, which occurs in 15 to 30 percent of children who contract the disease, due to inflammation damaging the nerve that conducts sound from the ear to the brain for processing. (chicagotribune.com)
  • Although group B meningococcal disease is relatively uncommon in Europe, it is more common in certain regions of Europe. (europa.eu)
  • Meningococcal C disease is a rare but life-threatening infection that occurs mainly in children and young adults. (laboratorytalk.com)
  • Students starting university and mixing with lots of new people, some of whom may unknowingly carry the meningococcal bacteria, are at risk of infection," said expert on meningococcal disease for PHE Shamez Ladhani. (laboratorytalk.com)
  • This overview aims to describe the main patterns of meningitis disease cases and pathogens from 1928 to 2018 in Africa with a special focus on disease conditions "out-of-the-belt" area that is still usually unexplored. (biomedcentral.com)
  • Formerly concentrated in the region of the meningitis belt with Sub-Saharan and Sudanian environmental conditions, the disease extends now outside these historical limits to reach more forested regions in the central parts of the continent. (biomedcentral.com)
  • Earlier this month, the Florida Department of Health and the US Centers for Disease Control and Prevention both detected an ongoing outbreak of meningococcal disease (meningitis) in Florida, with the number of cases so far this year already surpassing the 5-year average. (smh.com)
  • What are the symptoms of meningococcal disease? (awayclinic.com)
  • Meningococcal disease typically manifests 1-10 days after exposure. (awayclinic.com)
  • Meningococcal disease is fast-moving disease that has a case-fatality ratio of 10%-20%, even with antibiotic treatment. (awayclinic.com)
  • Approximately 40% of people with meningococcal disease present with meningococcal sepsis, known as meningococcemia. (awayclinic.com)
  • Among infants and children under 2 years old, meningococcal disease may have nonspecific symptoms. (awayclinic.com)
  • About 10-15% of those with meningococcal disease has been associated with fatality. (medthical.com)
  • It is more prevalent among children below 1 year old and also in college students among 16-21 years old.Those with asplenia (previously spleen removed ) are also at risk of meningococcal disease. (medthical.com)
  • It is endemic in East Africa, Mauritania in North Africa and South Africa and disease transmission occurs during periods of extreme flooding. (org.in)
  • For example, in 2014/15 MenW accounted for 24% of cases of meningococcal disease in England compared to only 1-2% in 2008/9. (meningitis.org)
  • The strain (ST-11) was identified using the MRF Meningococcal Genome Library to be a particular strain responsible for causing high disease rates and very high fatality rates in South America. (meningitis.org)
  • Meningococcal disease is spread from close and prolonged contact with an infected person through saliva or secretions (fluids) from the nose and throat. (gc.ca)
  • Can meningococcal disease be treated? (gc.ca)
  • Where is meningococcal disease a concern? (gc.ca)
  • Meningococcal disease occurs worldwide with seasonal variations. (gc.ca)
  • Invasive meningococcal disease can also present as arthritis and pneumonia. (nvic.org)
  • Meningococcal disease is not easily spread and requires one to be susceptible to the infection and to have regular close contact with a person who is colonizing the bacteria. (nvic.org)
  • Individuals most at risk for contracting meningococcal disease are infants, adolescents, young adults and seniors. (nvic.org)
  • Between 10-20 percent of individuals are asymptomatic carriers and colonize the bacteria that causes meningococcal disease in the back of their throats. (nvic.org)
  • Invasive meningococcal disease may cause permanent injury including brain damage, hearing loss, loss of a limb or death. (nvic.org)
  • Persons noted to be at highest risk of developing complication from meningococcal disease are those with certain genetic factors, HIV, smokers as well as those who have a family member with the disease. (nvic.org)
  • There are several different groups of meningococcal bacteria that cause disease. (alpinistory.ru)
  • Meningococcal disease is a very serious illness caused by bacteria. (alpinistory.ru)
  • Vaccinations against hepatitis A are also recommended as travel vaccinations, and vaccinations against hepatitis B, typhoid, rabies and meningococcal disease (ACWY) for long-term stays or special exposure. (agooddir.com)
  • What diseases occur in travelers, and how can disease be prevented? (okkii.com)
  • Errors by general practitioners, including failing to treat diabetes, failing to refer following symptoms of arterial blockage, Cauda Equina/Spinal abscesses, meningococcal disease and meningitis. (no5.com)
  • Your patients might not be familiar with meningococcal disease because it is relatively rare in the U.S. When it hits, though, it's nasty, leading to meningitis or bloodstream infections, among other ailments. (texmed.org)
  • Invasive meningococcal disease in elderly people, New South Wales, Australia, 1993 to 2012 Western Pacific Surveillance and Response Journal , 2012, 4(4):4-10. (who.int)
  • Little information is available publicly on invasive meningococcal disease (IMD) in elderly people in Australia. (who.int)
  • 2 In Australia, the highest rates of invasive meningococcal disease (IMD) are among children under 5 years and young adults between 15 and 24 years of age. (who.int)
  • There are five types (serogroups) of meningococcal bacteria that cause most disease worldwide: A, B, C, W, and Y. Serogroups B, C, and Y cause most of the illness seen in the United States. (wa.gov)
  • Meningitis is the most common form of meningococcal disease (50 percent of cases). (wa.gov)
  • If a person has symptoms of meningococcal disease, they usually appear anywhere from 3 to 4 days after exposure. (wa.gov)
  • Some people are carriers of meningococcal bacteria, but they have no symptoms of disease. (wa.gov)
  • In young children, doctors may also look at the child's reflexes for signs of meningococcal disease, specifically meningitis. (wa.gov)
  • Although it is rare, people can get meningococcal disease more than once. (wa.gov)
  • All preteens and teens should get vaccinated against meningococcal disease because there is a potential risk of reinfection for this age group. (wa.gov)
  • What makes meningococcal disease a serious illness? (wa.gov)
  • Even with antibiotic treatment, 10 to 15 in 100 people infected with meningococcal disease will die. (wa.gov)
  • Who is at risk for meningococcal disease? (wa.gov)
  • Anyone can get meningococcal disease, but rates of disease are highest in children younger than 1 year of age, followed by a second peak in adolescence. (wa.gov)
  • Among teens and young adults, those 16 through 23 years old have the highest rates of meningococcal disease. (wa.gov)
  • Other factors that may increase risk for meningococcal disease include household crowding, smoking, and having a viral infection that occurs before meningococcal infection. (wa.gov)
  • What is the best way to prevent meningococcal disease? (wa.gov)
  • The best protection against meningococcal disease is to get vaccinated. (wa.gov)
  • For over 100 years, major epidemics of meningococcal disease have occurred every few years within the African meningitis belt, which runs across the continent from Senegal to Ethiopia. (bvsalud.org)
  • Leadership Forum (MLF), in Dubai in May 2010 to exchange opinions on meningococcal disease and prevention strategies. (who.int)
  • Current travel guidelines for preven- iours (e.g. kissing, coughing, smoking) onstrated for serogroups C and W135 tion of meningococcal disease vary from all increase exposure to the bacteria [1]. (who.int)
  • Prevention and control of meningo- coccal disease and Meningococcal disease and college students: recommenda- tions of the Advisory Committee on Immunization Practices (ACIP). (cdc.gov)
  • Since then, meningococcal outbreaks in the meningitis belt have primarily been due to serogroups C and W. A few serogroup X outbreaks have also been reported. (wikipedia.org)
  • However, several outbreaks of serogroups B (NmB) and C (NmC) have occurred. (medpagetoday.com)
  • Therefore, this study aimed to establish the trends in N. meningitidis serogroups from 2016 to 2020 in Ghana's meningitis belt. (springer.com)
  • With current methods, the timing of future outbreaks is unpredictable, and tools that identify the key environmental factors associated with areas prone to meningitis epidemics would help us to understand the basis for these outbreaks and eventually optimize prevention and control activities. (cdc.gov)
  • Since the early 1900s, large and unpredictable outbreaks of meningococcal meningitis have occurred in regions of sub-Saharan Africa. (chop.edu)
  • The Meningococcus (Infections) bacterium has been the source of most of the " meningitis " outbreaks across North America over the last 2 decades. (drpaul.com)
  • This is why outbreaks of infection occur more frequently in crowded conditions such as in the army, school, or dormitory settings. (drpaul.com)
  • Are meningitis outbreaks common? (smh.com)
  • But it does happen from time to time in certain groups who tend to live together or congregate, especially college students, because they group together and they're at the right age where most of these outbreaks occur. (smh.com)
  • Now these outbreaks tend to be rather protracted, and cases don't occur all at the same time. (smh.com)
  • What should people do to protect themselves from meningitis outbreaks? (smh.com)
  • Anyone living or working with the local population (e.g. health care workers) in areas where meningitis is present or outbreaks are occurring (such as the sub-Saharan African meningitis belt ). (gc.ca)
  • In sub-Saharan Africa, where the meningitis belt extends from Senegal to Ethiopia, most outbreaks occur from December to June. (gc.ca)
  • However, outbreaks continue to occur, including in Texas. (texmed.org)
  • A study has suggested that, at least in children, CSF sterilization may occur more rapidly after initiation of parenteral antibiotics than previously suggested, with complete sterilization of meningococcus within 2 hours and the beginning of sterilization of pneumococcus by 4 hours. (medscape.com)
  • Serogroup A meningococcus is implicated in a significant number of epidemics of meningitis that occur in the African meningitis belt and China but rarely in industrialised countries. (springer.com)
  • ULTOMIRIS increases your chance of getting serious and life-threatening meningococcal infections that may quickly become life-threatening and cause death if not recognized and treated early. (biospace.com)
  • Although factors predisposing populations to meningitis epidemics are poorly understood, population susceptibility, introduction of new strains, poor living conditions, and concurrent infections have all been implicated. (cdc.gov)
  • Meningococcal infections in the nasopharynx may cause no symptoms-up to 30 percent of the population may harbour the bacteria between epidemics . (britannica.com)
  • Infections of the lining of the brain and spinal cord in the central nervous system can result in meningococcal meningitis. (britannica.com)
  • Meningococcal infections can be very serious, and can lead to meningitis and even death. (cdc.gov)
  • These infections are not very common - an estimated 1,400 to 2,800 cases occur in the United States annually. (cdc.gov)
  • Research shows that over 70% of these infections occur in children under the age of five. (medicalnewstoday.com)
  • One of the difficulties with treating meningococcal infections is that they can spread so quickly and cause such an overwhelming infection, that even antibiotics and other supportive treatments can't always stop the infection. (drpaul.com)
  • Toxic deafness may result from exposure to such agents as salicylates, diuretics, or aminoglycoside antibiotics, or be due to infections of the central nervous system (meningococcal meningitis, syphilis) or of the eighth cranial nerve. (tabers.com)
  • Is meningitis exasperated by COVID or flu or other respiratory infections? (smh.com)
  • Your patients might not have heard of pneumococcal bacteria, but they probably know some of its serious conditions: pneumonia, meningitis, sinusitis, blood infections, and ear infections. (texmed.org)
  • The African meningitis belt is a region in sub-Saharan Africa where the rate of incidence of meningitis is very high. (wikipedia.org)
  • In the African meningitis belt, the WHO defines a meningococcal epidemic as at least 100 cases per 100,000 inhabitants in a year. (wikipedia.org)
  • Comparative epidemiologic study of meningococcic cerebrospinal meningitis in temperate regions and in the meningitis belt in Africa. (wikipedia.org)
  • However, serogroup W also causes endemic diseases in some African meningitis belt countries. (springer.com)
  • Serogroup A epidemics in Africa's meningitis belt occur every 8-12 years, with each wave following a gradual increase in volume-decrease in the volume of cases pattern [ 14 ]. (springer.com)
  • Although meningococcal meningitis is endemic in various regions worldwide, its burden is remarkable in 26 countries comprising the 'meningitis belt' of subSaharan Africa, stretching from Senegal in the west to Ethiopia in the east [ 16 ]. (springer.com)
  • Epidemics in Africa are most prevalent in all or parts of 18 countries that stretch across sub-Saharan Africa, commonly referred to as the Meningitis Belt. (chop.edu)
  • High-risk groups for contracting infection include travellers to endemic areas including the sub-Saharan African meningitis belt, young children, adolescents and individuals living in crowded quarters Footnote 2 . (canada.ca)
  • and they cannot be pilgrims (640 per 100 000) and their tors associated with bacterial carriage: boosted--on the contrary, repeated contacts (up to 28 per 100 000) and crowded conditions (e.g. military bar- polysaccharide vaccinations result in peaks during meningitis belt epidemics racks, dormitories, pubs, events), travel a reduced immune response (hypo- (up to 800 per 100 000) [13]. (who.int)
  • In children, the first symptoms of meningitis are usually a fever , severe headache , and vomiting . (medicalnewstoday.com)
  • Although fever is one of the most telling signs of meningitis, it is often absent in babies younger than 3 months old. (medicalnewstoday.com)
  • 2. 'High fever, headache, and stiff neck are common symptoms of meningitis in anyone over the age of 2 years. (weber.edu)
  • Sudden onset occurs in 1 to 7 days after infection with fever, intense headache, nausea, vomiting, stiff neck, petechial rash, pink macules, and even loss of consciousness and sleeping sickness. (gov.tw)
  • Meningitis symptoms can include a blotchy red rash, fever, vomiting and stiffness, which can lead to blood poisoning and in some cases can be fatal. (laboratorytalk.com)
  • For meningitis, you get hit with a very severe headache, fever, and body aches. (smh.com)
  • Meningococcal meningitis is characterized by sudden onset of headache, fever, and neck stiffness. (awayclinic.com)
  • Dengue fever, transmitted by mosquitoes, occurs along the Red Sea coast. (agooddir.com)
  • Leishmaniasis and West Nile fever occur. (agooddir.com)
  • Knowing whether meningitis is caused by a virus or bacterium is important because the severity of illness and the treatment differ. (weber.edu)
  • This infection is dangerous because, in addition to causing meningitis, the bacteria can enter the bloodstream (referred to as meningococcemia) and cause the body to go into shock, resulting in kidney failure and unfortunately, possibly death. (drpaul.com)
  • This occur when the bacteria enters the bloodstream and disseminate throughout the body. (medthical.com)
  • This infection commonly occurs when bacteria from an upper respiratory infection enter the bloodstream. (alpinistory.ru)
  • We describe a model that predicts the probability, based on environmental information, of an area experiencing an epidemic of meningitis. (cdc.gov)
  • During the first 6 months of 1983, an epidemic of serogroup A meningococcal meningitis, resulting in 875 cases and 95 deaths, occurred in the Kathmandu valley of Nepal. (cdc.gov)
  • These diseases occur endemically, meaning that there's a background rate of occurrence, but they can also occur in an epidemic way like this one-in a cluster where you get more cases occurring in a geographically concentrated area, among groups of people or in a certain city or college and so forth. (smh.com)
  • The objectives of this review were to revise WHO guidelines on control of epidemic meningitis in subSaharan Africa conce. (bvsalud.org)
  • It was also higher for those with meningococcal pneumonia when compared to meningococcal meningitis. (cdc.gov)
  • Four cases had meningitis, 3 had bacteremia without another focus of infection, 1 had pneumonia, and 1 had tracheobronchitis. (mn.us)
  • Details of all known meningitis epidemics occurring before 2000 in countries comprising continental Africa were compiled from information documented in the published literature and unpublished institutional reports at the end of June 2001. (cdc.gov)
  • In Africa, epidemics have been cyclic, occurring every 10-12 years and lasting 2-3 years. (cdc.gov)
  • Among Nm, serogroup A used to be responsible for up to 80 to 85% of meningococcal meningitis cases in Africa. (biomedcentral.com)
  • Based on basic spatio-temporal methods, and a 90-years database of reported suspected meningitis cases and death from the World Health Organization, we used both geographic information system and spatio-temporal statistics to identify the major localizations of meningitis epidemics over this period in Africa. (biomedcentral.com)
  • The most dramatic impacts of climate change and variability in Africa were probably best observed in the 1990s when multiple El Niño and La Niña events occurred. (org.in)
  • Over 90 per cent of the global malaria burden occurs in Africa and is associated with considerable mortality and morbidity. (org.in)
  • Occurs in sub-Saharan Africa, Saudi Arabia and India. (glphysician.com)
  • Occurs in tropical and subtropical regions of Africa and South America. (glphysician.com)
  • In the case of meningococcal meningitis, other symptoms can include stiff neck , vomiting , confusion, and photophobia (increased sensitivity of the eyes to light). (britannica.com)
  • Meningitis is an infection of the membranes covering the brain and spinal cord. (medlineplus.gov)
  • If the provider thinks meningitis is possible, a lumbar puncture ( spinal tap ) will likely be done to obtain a sample of spinal fluid for testing. (medlineplus.gov)
  • Meningitis is an inflammation of the protective tissues and fluid surrounding the brain and spinal cord. (medicalnewstoday.com)
  • 1. 'Meningitis is an infection of the fluid of a person's spinal cord and the fluid that surrounds the brain. (weber.edu)
  • People sometimes refer to it as spinal meningitis. (weber.edu)
  • Meningitis is an infection that affects the membranes that surround the brain and spinal cord, known as the meninges. (awayclinic.com)
  • In some cases, people with meningitis may also receive corticosteroids, which can reduce inflammation and swelling around the brain and spinal cord. (awayclinic.com)
  • Meningitis is an inflammation of the covering of the brain and spinal cord---also called the meninges. (lisd.net)
  • Meningitis is the infection of the membrane lining of the brain and spinal cord. (medthical.com)
  • Meningitis is a medical term that refers to an inflammation of the membranes that cover the brain and spinal cord (meninges). (alpinistory.ru)
  • Meningitis is most often caused by a bacterial or viral infection that moves into the cerebral spinal fluid (CSF). (alpinistory.ru)
  • Meningitis is an infection of the meninges (a thin lining covering the brain and spinal cord) caused by any one of a number of different bacteria. (alpinistory.ru)
  • when they infect blood, it's called meningococcal bacteremia. (cdc.gov)
  • One death occurred in a case less than 1 year of age with bacteremia attributed to serogroup C. (mn.us)
  • For example, you can brush your teeth and get bacteremia for a short time and have no SIRS (Systemic Inflammatory Response Syndrome) criteria occur. (medicinenet.com)
  • If a person ever develops such a rash, especially in the context of an outbreak of meningococcal infection, medical attention should be sought immediately. (drpaul.com)
  • A simple cold or respiratory tract infection can also lead to meningitis. (medicalnewstoday.com)
  • Meningitis spreads through sneezing, coughing or direct contact with an infected person's respiratory secretions. (awayclinic.com)
  • There are many different subtypes of the bacteria, but five of the subtypes (A, B, C, Y and W135) are responsible for the majority of meningococcal cases. (gc.ca)
  • This report published in Communicable Diseases Intelligence Volume 25, No 3, August 2001 contains the annual report of the Australian Meningococcal Surveillance Programme, 2000. (health.gov.au)
  • Every year, more meningococcal meningitis diseases are registered during the dry season from December to May. (agooddir.com)
  • Meningitis can quickly become a life-threatening illness. (medlineplus.gov)
  • Teens are at an increased risk of meningococcal meningitis due to common everyday activities such as sharing utensils and water bottles, and kissing.4,5,6 Meningococcal meningitis has a 10-15% fatality rate and cases have occurred in which an otherwise healthy young person will contract the illness, become severely sick, and die in as little as 24 hours after the first symptoms appear. (immunize.org)
  • Meningitis caused by bacteria is considered more serious and can lead to severe illness and death. (awayclinic.com)
  • It is known that meningococcal bacteria spread from person to person by close, prolonged contact and exhalation or inhalation of droplets that contain these bacteria. (meningitisnow.org)
  • It is fatal in one in 10 cases and one in 7 survivors is left with a severe handicap, such as deafness or brain injury' (Meningitis Foundation of America). (weber.edu)
  • In severe cases, meningitis can lead to brain damage, hearing loss, and other serious complications. (awayclinic.com)
  • For example, malaria became endemic in the Central Kenya highlands after 1993 when the mean temperature permanently exceeded 18°C. Prior to the ongoing malaria control efforts, severe epidemics occurred in the East African highlands during El Niño years, resulting in 100 per cent increase in hospital admissions. (org.in)
  • It commonly occurs in children and adults, though young children are more susceptible to the infection. (medicalnewstoday.com)
  • As for adults who were never vaccinated for meningitis, it's a good idea to talk to your physician about getting vaccinated if you are planning to travel overseas, are entering the military or have an immune deficiency. (chicagotribune.com)
  • This could provide a degree of herd protection against meningitis if implemented in a campaign in which high transmission occurs, for example in teenagers and young adults," said Read. (laboratorytalk.com)
  • The trial enrolled adults with suspected meningitis and randomized them to either dexamethasone 10mg IV q6hrs x4 days started 15-20 minutes before the first IV antibiotics or a placebo IV with the same administration schedule. (medicine52in52.com)