AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, AgricultureInformation ScienceHealth Care
Intracranial AneurysmAneurysmAneurysm, RupturedEmbolization, TherapeuticCerebral AngiographySubarachnoid HemorrhageAngiography, Digital SubtractionAneurysm, InfectedAortic AneurysmSurgical InstrumentsMagnetic Resonance AngiographyHeart AneurysmAortic Aneurysm, ThoracicBalloon OcclusionAneurysm, DissectingEndovascular ProceduresTreatment OutcomeMechanical ThrombolysisTomography, X-Ray ComputedRupture, SpontaneousCerebral ArteriesNeurosurgical ProceduresCarotid Artery, InternalIliac AneurysmStentsImaging, Three-DimensionalBlood Vessel ProsthesisCoronary AneurysmPlatinumBlood Vessel Prosthesis ImplantationGlasgow Outcome ScaleVascular Surgical ProceduresFollow-Up StudiesRetrospective StudiesRetreatmentAneurysm, FalsePosterior Cerebral ArteryAortic RuptureIntracranial ThrombosisAngiographyMicrosurgeryCircle of WillisCerebral RevascularizationPostoperative ComplicationsEquipment DesignCarotid Artery DiseasesAnterior Cerebral ArteryAorta, AbdominalBasilar ArteryCoronary OcclusionEquipment Failure AnalysisAortographyVertebral ArteryTime FactorsCoated Materials, BiocompatibleArterial Occlusive DiseasesRetinal Vein OcclusionRisk FactorsRetinal Artery OcclusionCraniotomyRecurrenceIntracranial Arteriovenous MalformationsPancreatic ElastaseModels, CardiovascularCerebral HemorrhageIntraoperative ComplicationsProsthesis DesignCerebrovascular CirculationProspective StudiesSensitivity and SpecificityPolyvinylsNeurologic ExaminationProstheses and ImplantsImage Processing, Computer-AssistedIncidental FindingsIschemic Attack, TransientIntracranial EmbolismOphthalmic ArteryRadiography, InterventionalFeasibility StudiesVasospasm, IntracranialLoeys-Dietz SyndromeBrain IschemiaMarfan SyndromeCatheterizationDental OcclusionCerebral Arterial DiseasesMiddle Cerebral ArteryMagnetic Resonance ImagingForeign-Body MigrationCarotid Artery, Internal, DissectionContrast MediaIliac ArteryBrain Hemorrhage, TraumaticLigationPolycystic Kidney, Autosomal DominantTomography, Spiral ComputedDisease Models, AnimalCarotid Artery, ExternalHemodynamics
Subarachnoid hemorrhageRuptureArteryAngiographyStentsCoilAngiographicHemorrhageNeckCerebral AneurysmCoilsSmall aneurysmsComplicationsRetreatment ratesRecurrenceVesselSaccular aneurysmsPipeline Embolization DeviceClinicalGiant aneurysmsVascularEmbolization of intracranialSafety and efficacyUnruptured and rupturedMulticenterPatients with rupturedIschemic strokeRuptured or unruptured aneurysmPosteriorBasilarAbstractThromboembolicComplete occlusion ratesTreated aneurysms were includedManagement of unrupturedNeurosurgeryCerebrovascular DiseasesCentersSystematic ReviewStenosis or aneurysmMorphologyVesselsPolycystic kidneyFlow diversion
Subarachnoid hemorrhage5
Rupture13
  • One patient experienced abrupt in-stent thrombosis resulting in a transient neurologic deficit, and 1 patient died due to rupture of a coexisting aneurysm. (ajnr.org)
  • 1 Flow conditions within the parent artery and the aneurysm itself have long been thought to play an important role in aneurysm growth and rupture. (ajnr.org)
  • Our review suggests that SFD achieves comparable AOR to its contemporary, the Pipeline Embolization Device (ev3 Endovascular, Plymouth, MN, USA) but has a higher rate of higher rate of ischemic complications, aneurysm rupture and mortality. (nih.gov)
  • Although fibrinoid necrosis and Charcot-Bouchard aneurysms (CBAs) have been postulated to underlie vessel rupture in ICH, the role and significance of CBAs in ICH has been controversial. (nature.com)
  • The International Study of Unruptured Intracranial Aneurysms (ISUIA) indicated a relatively low risk of rupture in small aneurysms without history of SAH. (medscape.com)
  • The presence of cigarette smoking, family history of aneurysms, polycystic kidney disease, or systemic lupus erythematosus may elevate the risk of rupture and should be considered. (medscape.com)
  • The occurrence, growth, thrombosis, and even rupture of intracranial saccular aneurysms can be explained by abnormal hemodynamic shear stresses on the walls of large cerebral arteries, particularly at bifurcation points. (medscape.com)
  • Unruptured aneurysms do not usually cause symptoms, unless they rupture or when they compress adjacent neural structures causing focal neurological deficits. (hindawi.com)
  • At last angiographic follow-up (n = 55), 7.5 ± 4.2 months post-procedure, 32 aneurysms (57.1%) were graded as RRC I, 7 (12.5%) RRC II, and 17 RRC III (30.4%).Clinical complications, excluding death, were seen in 4 patients (6.8%) including 1 delayed aneurysm rupture and 3 symptomatic ischaemic events. (bvsalud.org)
  • Can We Explain Machine Learning-based Prediction For Rupture Status Assessments of Intracranial Aneurysms? (cdc.gov)
  • For subgroup analysis, LVIS stents were associated with a significantly higher rate of complete occlusion ( P = 0.014) and a lower rate of intraprocedural rupture ( p = 0.021). (frontiersin.org)
  • Ruptured Aneurysms: Diagnosis, Management and Treatment: Imaging paradigms of ruptured aneurysms, management options for co-morbidities associated with aneurysm rupture, treatment options including coiling, clipping, flow diverter stents, flow disruptors 5. (intechopen.com)
  • The natural history of saccular intracranial aneurysms consists of three phases: initiation, growth, and either stabilization or rupture, and the application of scientific principles to biological processes has made it easier to understand the behavior of aneurysm formation and rupture. (intechopen.com)
Artery30
  • Treatment of large, wide-neck, or otherwise untreatable aneurysms with functional reconstruction of the parent artery may be achieved with relative safety using dedicated flow-modifying devices with or without adjunctive use of intrasaccular coil packing. (ajnr.org)
  • 1 - 3 Early experimental work suggested 3 potential mechanisms of action: improved anatomic reconstruction of the parent artery, functional modification of flow across the orifice of the aneurysm, and biologic repair of the aneurysm neck by neointimal overgrowth. (ajnr.org)
  • 4 - 11 Yet, the early application of stent-assisted aneurysm therapy was primarily focused on geometric reconstruction of the parent artery through improved coil packing of the aneurysm. (ajnr.org)
  • Ischemic complications and parent artery occlusion each occurred in 10% of patients. (nih.gov)
  • Treatment methods were observation ( n = 6), stent-assisted coil embolization ( n = 9), parent artery occlusion ( n = 6), and flow diversion ( n = 7). (ajnr.org)
  • Improvement of the mRS score on follow-up was observed in the flow diversion (6/7, 85.7%) and parent artery occlusion (4/6, 66.7%) groups but not in the stent-assisted coil embolization and observation groups. (ajnr.org)
  • A worsened mRS score was most common in the observation group (4/6, 66.7%), followed by stent-assisted coil embolization (3/9, 33.3%), parent artery occlusion (2/6, 33.3%), and flow diversion (0/7, 0%) groups. (ajnr.org)
  • When treating intracranial vertebrobasilar dissecting aneurysms with brain stem compression, parent artery occlusion and flow diversion should be considered to reduce aneurysm size and improve the mRS score. (ajnr.org)
  • of these patients, 37 had carotid artery aneurysms below the origin of the ophthalmic artery, 21 had aneurysms arising from the supraclinoid portion of the carotid artery, six had basilar trunk aneurysms, and one had a distal vertebral aneurysm. (thejns.org)
  • Of 67 patients who underwent a formal occlusion test, eight with carotid artery aneurysms did not initially tolerate the occlusion test, and ischemic signs disappeared instantaneously with deflation and removal of the balloon. (thejns.org)
  • Ipsilateral internal or common carotid artery occlusion. (mayo.edu)
  • It is mainly effective in wide neck unerupted saccular aneurysms, that are difficult to coil because of the tendency of the coils to fill the parent artery (referred to as prolapse). (wikipedia.org)
  • These devices can be used to treat aneurysms by doing a cerebral angiogram via femoral artery or radial artery access. (wikipedia.org)
  • The patency status of the parent artery is evaluated on a three-point scale, from no change in the parent artery diameter to parent artery occlusion. (wikipedia.org)
  • Besides one basilar apex aneurysm, all aneurysms were located at the anterior communicating artery (AComA) complex. (springer.com)
  • Aneurysm is an abnormal local dilatation in the wall of a blood vessel, usually an artery, due to a defect, disease, or injury. (medscape.com)
  • Giant proximal carotid artery aneurysms are in many ways the prototype for all giant aneurysms. (elsevierpure.com)
  • White, J & Replogle, RE 2005, ' Microsurgical and endovascular treatment of giant internal carotid artery aneurysms ', Operative Techniques in Neurosurgery , vol. 8, no. 2, pp. 78-84. (elsevierpure.com)
  • Replogle, Robert E. / Microsurgical and endovascular treatment of giant internal carotid artery aneurysms . (elsevierpure.com)
  • The composite primary efficacy end point of complete aneurysm occlusion (Raymond-Roy 1) without parent artery stenosis or aneurysm retreatment was achieved in 84.7% (95% CI, 78.6%-90.9%) of patients. (escholarship.org)
  • A machine learning model for non-invasive detection of atherosclerotic coronary artery aneurysm. (cdc.gov)
  • Surgical management of ruptured middle cerebral artery aneurysms with large intraparenchymal or sylvian fissure hematomas. (neurosurgery.directory)
  • We present a 61-year-old female with an unruptured intracranial aneurysm on the left superior hypophyseal artery. (neurointervention.org)
  • Multiple embolic infarction and total occlusion of the left internal carotid artery (ICA) was occurred one day later. (neurointervention.org)
  • Temporary artery clipping facilitates safe cerebral aneurysm management, besides a risk for cerebral ischemia. (sharif.edu)
  • We developed an artificial neural network (ANN) to predict the safe clipping time of temporary artery occlusion (TAO) during intracranial aneurysm surgery. (sharif.edu)
  • A cerebral aneurysm is defined as a local outpouching of an intracranial artery and can either be saccular or fusiform. (intechopen.com)
  • Lateral projection of a left common carotid artery injection that displays the order of branching in the intracranial carotid, including 1: ophthalmic, 2: posterior communicating, 3: anterior choroidal, and 4: anterior cerebral arteries. (medscape.com)
  • The est prevalence is reported from Turkey, with BD tend to be multiple and pul- patient was given oral acetazolamide, 80-370per100000,andrangesfrom2 monary artery aneurysms are relatively 125mgtwiceaday. (who.int)
  • According to the severe course in men and in those with repair of pulmonary artery aneurysm in international criteria for diagnosis [ 4 ], onsetbefore25yearsofage[ 2 ]. (who.int)
Angiography11
  • Angiography at 6 months demonstrated complete occlusion in 17 and partial filling in 1 of 18 patients. (ajnr.org)
  • Examination for treatment selection included assessment of the circle of Willis by compression angiography and xenon blood flow studies, with the ultimate evaluation being test occlusion under systemic heparinization with the balloon temporarily placed in the desired position. (thejns.org)
  • Regression or evolution of these aneurysms is monitored with serial angiography. (medscape.com)
  • We report a rare case of recurrence of a large intracavernous aneurysm after angiography proved complete occlusion. (bmj.com)
  • Digital subtraction angiography (DSA) is still considered the gold standard among the currently used imaging methods for the diagnosis of an intracranial aneurysm. (hindawi.com)
  • Rotational angiograph and 3-D CT angiography are useful in understanding the vascular morphology while MRI scanning helps determine the true size of the lesion and evaluate the condition of the surrounding brain and the relationship of the aneurysm to such structures as the optic nerve. (elsevierpure.com)
  • Methods The success of aneurysm obliteration was assessed within 2 weeks after surgery by digital subtraction angiography (DSA). (neurosurgery-blog.com)
  • Artificial Intelligence Application to Screen Abdominal Aortic Aneurysm Using Computed tomography Angiography. (cdc.gov)
  • Cerebral Angiography under Artificial Intelligence Algorithm in the Design of Nursing Cooperation Plan for Intracranial Aneurysm Patients in Craniotomy Clipping. (cdc.gov)
  • Multidimensional Deep Learning Reduces False-Positives in the Automated Detection of Cerebral Aneurysms on Time-Of-Flight Magnetic Resonance Angiography: A Multi-Center Study. (cdc.gov)
  • 34: Turner RD, Vargas J, Turk AS, Chaudry MI, Spiotta AM. Novel device and technique for minimally invasive intracerebral hematoma evacuation in the same setting of a ruptured intracranial aneurysm: combined treatment in the neurointerventional angiography suite. (neurosurgery.directory)
Stents7
  • A few clinical case reports, however, suggested that improved outcomes associated with the use of stents may be attributable to stent-induced modification of flow within and around the aneurysm, 12 , 13 providing the impetus for development of higher coverage endoluminal sleeves for the treatment of cerebral aneurysms. (ajnr.org)
  • Flow diverter stents in the treatment of intracranial aneurysms: Where are we? (wikipedia.org)
  • 14 ] While the development of intracranial stents has enhanced treatment of wide-necked aneurysms, there is reluctance to use this technology during the acute posthemorrhage period. (surgicalneurologyint.com)
  • 20 ] Balloon remodeling has provided an alternative to intracranial stents especially since it can be used without antiplatelet therapy. (surgicalneurologyint.com)
  • Currently, the stent has been used widely in various diseases such as cervical carotid stenosis, intracranial stenosis, dissecting aneurysms and intracranial wide-neck aneurysms, where stents are placed across the neck of an aneurysm to allow for coil deployment into the aneurysm without compromising the parent vessel. (neurointervention.org)
  • Since its debut as an endovascular aid, Neuroform stents (Stryker, Kalamazoo, MI, USA) were quickly followed by other stents, and each stent targets aneurysms of specific shapes and parent patterns ( 11 ). (frontiersin.org)
  • Thirty-one aneurysms were treated with the support of different applications ( n = 32) of the Solitaire AB stents followed by the standard coiling procedure ( n = 30). (neurologyindia.com)
Coil13
  • There was no difference between coil-packed and unpacked aneurysms. (ajnr.org)
  • Flow diverters are treatment for intracranial aneurysms alternative to endosaccular coil embolization, although the techniques can be combined, especially in large/giant aneurysms. (wikipedia.org)
  • Stent-assisted coil embolization is an option for treatment of ruptured wide neck ruptured aneurysms and for salvage treatment during unassisted embolization of ruptured aneurysms but complications and retreatment rates are higher than for routine clipping or coiling of cerebral aneurysms. (surgicalneurologyint.com)
  • CONCLUSIONS: Clinical outcomes of the Surpass flow diverter in the treatment of intracranial aneurysms show a safety profile that is comparable with that of stent-assisted coil embolization. (umassmed.edu)
  • Since the International Subarachnoid Aneurysm Trial demonstrated its safety and efficacy, endovascular treatment (EVT) involving coil embolization has been a mainstay of treatment for both unruptured and ruptured intracranial aneurysms [ 1 ]. (e-jnc.org)
  • At most centers, coil embolization for ruptured intracranial aneurysm (RIA) is performed under general anesthesia (GA), which provides optimal conditions for the procedure [ 2 ]. (e-jnc.org)
  • We enrolled 245 patients with ruptured tiny intracranial aneurysms treated with coil embolization. (frontiersin.org)
  • BACKGROUND: Two types of treatment are being used for patients with ruptured intracranial aneurysms: endovascular detachable-coil treatment or craniotomy and clipping. (ox.ac.uk)
  • and Packing Coil, which is uniquely designed to pack densely behind Ruby and POD to occlude arteries and veins throughout the peripheral vasculature, including aneurysms. (penumbrainc.com)
  • To report patients with intracranial wide-necked or complex aneurysms who underwent Solitaire stent-assisted coil embolization. (neurologyindia.com)
  • The Penumbra SMART COIL System is comprised of COMPLEX and WAVE ™ coils designed for framing, filling, and finishing intracranial aneurysms and embolising vascular malformations. (shinsokai.com)
  • Background and purpose The HydroSoft coil was developed as a finishing coil, ideally to be placed along the aneurysm neck to enhance intracranial aneurysm healing. (elsevierpure.com)
  • The GEL THE NEC (Gaining Efficacy Long Term: Hydrosoft, an Emerging, New, Embolic Coil) multicenter registry was developed to assess the safety and efficacy of HydroSoft coils in treating intracranial aneurysms. (elsevierpure.com)
Angiographic11
  • Immediate angiographic occlusion was achieved in 4 and flow reduction, in another 15 aneurysms. (ajnr.org)
  • In terms of angiographic distribution, 86.8% of aneurysms were located in the anterior circulation and 13.2% in the posterior circulation. (nih.gov)
  • [ 1 ] Published data vary according to the definition of what constitutes an aneurysm and whether the series is based on autopsy data or angiographic studies. (medscape.com)
  • Six month angiographic follow-up demonstrated complete occlusion. (bmj.com)
  • Unfortunately, obvious aneurysm recurrence was confirmed on 2 year angiographic follow-up. (bmj.com)
  • Seven of 21 patients (33%) with angiographic follow-up required further treatment of the coiled aneurysm. (surgicalneurologyint.com)
  • We present preliminary clinical and angiographic results of an experimentally optimized Surpass flow diverter for treatment of intracranial aneurysms in a prospective, multicenter, nonrandomized, single-arm study. (umassmed.edu)
  • Angiographic results showed a high rate of intracranial aneurysm occlusion. (umassmed.edu)
  • The angiographic follow-up outcomes showed that the SAC group had a higher complete occlusion rate and lower recurrence rate (88.2 vs. 67.1%, 5.4 vs. 15.2%, P = 0.001). (frontiersin.org)
  • The following variables were obtained: demographics/ comorbidities, aneurysm geometry, adjunctive devices used, proportion of patients in whom HydroSoft coils were successfully placed, and long-term angiographic outcomes (graded by an independent core laboratory using the Modified Raymond Scale), and procedure-related adverse events. (elsevierpure.com)
  • At last angiographic follow-up (mean 9.0±6.3 months), the complete occlusion rate was 63.2% (280/442) and near complete occlusion rate was 25.2% (107/442). (elsevierpure.com)
Hemorrhage5
  • Infectious aneurysms are friable, with an increased propensity for hemorrhage. (medscape.com)
  • History of major symptomatic intracranial hemorrhage within 12 months that was not related to anticoagulation. (mayo.edu)
  • Prior Intracranial hemorrhage that the investigator believes represents a contraindication to the perioperative or periprocedural antithrombotic and antiplatelet treatments necessary to complete endarterectomy or stenting per protocol. (mayo.edu)
  • One patient had a spontaneous parenchymal hemorrhage contralateral to the treated aneurysm discovered 10 days after treatment. (surgicalneurologyint.com)
  • El Naamani K, Abbas R, Ghanem M, Mounzer M, Tjoumakaris SI, Gooch MR, Rosenwasser RH, Jabbour PM. Resuming Anticoagulants in Patients With Intracranial Hemorrhage: A Meta-Analysis and Literature Review. (jefferson.edu)
Neck16
  • A total of 19 wide-neck aneurysms were treated in 18 patients: 10 by implantation of PEDs alone and 9 by a combination of PED and coils. (ajnr.org)
  • we considered these to have a high likelihood of failure and/or recurrence with conventional endovascular techniques either because of a large or giant aneurysm or an unfavorable neck-to-sack ratio. (ajnr.org)
  • On multivariate analysis only history of smoking, location of occlusion, aneurysm size, wide neck aneurysm, stent-assisted coiling, female sex and history of hypertension were associated with complete occlusion. (bmj.com)
  • The internal elastic membrane is reduced or absent, and the media ends at the junction of the aneurysm neck with the parent vessel. (medscape.com)
  • All aneurysms were wide-necked with a mean dome-to-neck ratio of 1.5. (springer.com)
  • Rates of adequate occlusion (complete occlusion to neck remnant) and retreatment at last follow-up were 84.8% (95% CI 73% to 96.6%) and 4.5% (95% CI 2.2% to 6.8%), respectively. (bmj.com)
  • BACKGROUND AND PURPOSE: Incomplete occlusion and recanalization of large and wide-neck brain aneurysms treated by endovascular therapy remains a challenge. (umassmed.edu)
  • After analyzing each case, the following characteristics were important indications for the use of the FD: (1) aneurysm fusiform appearance, (2) very wide neck, and (3) our lack of experience in by-pass in children. (surgicalneurologyint.com)
  • The primary study results of the anterior circulation aneurysm cohort of the treatment of wide-neck, saccular, intracranial, aneurysms with the Neuroform Atlas Stent System (ATLAS trial [Safety and Effectiveness of the Treatment of Wide Neck, Saccular Intracranial Aneurysms With the Neuroform Atlas Stent System]) are presented. (escholarship.org)
  • A total of 182 patients with wide-neck anterior circulation aneurysms at 25 US centers were enrolled. (escholarship.org)
  • Mean aneurysm size was 6.1±2.2 mm, mean neck width was 4.1±1.2 mm, and mean dome-to-neck ratio was 1.2±0.3. (escholarship.org)
  • Aneurysm neck geometry might influence the efficacy of the flow diverter. (edu.au)
  • All baseline characteristics were equivalent between the two groups except for aneurysm size and dome-to-neck aspect ratio. (frontiersin.org)
  • Notably, the unique structural characteristics of tiny intracranial aneurysms, such as very small size, thin aneurysm wall, and relatively wide neck, make it difficult and challenging for both clipping and endovascular treatment ( 4 ). (frontiersin.org)
  • YOKNEAM, Israel & MIAMI-(BUSINESS WIRE)- Rapid Medical ™, a leading developer of advanced neurovascular devices, today announced new clinical data showing significant advantages of its novel COMANECI™ embolization assist device over established techniques to treat ruptured wide-neck intracranial aneurysms. (novumpr.nl)
  • It has been used in over 12,000 procedures worldwide in wide-neck aneurysm treatments-and in Europe only-to open arteries constricted by vasospasm. (novumpr.nl)
Cerebral Aneurysm2
  • The purpose of this study is to retrospectively review our experience with stent-assisted embolization of patients with an acutely ruptured cerebral aneurysm. (surgicalneurologyint.com)
  • Medical records and imaging were reviewed for 36 patients who underwent stent-assisted embolization of a ruptured cerebral aneurysm. (surgicalneurologyint.com)
Coils5
  • This study aimed to investigate the predictors of complete occlusion with endovascular coiling using SMART coils. (bmj.com)
  • Conclusion This study identified the rate and predictors of complete occlusion using SMART coils. (bmj.com)
  • The aneurysm was treated by a combination of a Tubridge flow diverter and coils, and balloon angioplasty, after flow diverter devices deployment for parent vessel stenosis. (bmj.com)
  • 2) intracranial aneurysms in the anterior circulation treated with the Neuroform Atlas Stent and approved coils. (escholarship.org)
  • The LANTERN Microcatheter is designed to assist in the delivery of diagnostic agents, such as contrast media, and therapeutic devices, such as occlusion coils, to the peripheral vasculature. (penumbrainc.com)
Small aneurysms2
  • CBAs, also known as miliary aneurysms or microaneurysms, are small aneurysms that arise from arterioles usually less than 300 µm in diameter [ 18 ]. (nature.com)
  • PREMIER: Flow Diversion Effective for Small Aneurysms Results of a new trial show high occlusion and low retreatment rates of intracranial aneurysms approximately 7 mm in size with the Pipeline Embolization Device, already approved for larger aneurysms. (medscape.com)
Complications7
  • 10, use of SFD only, data on complications and aneurysm occlusion rate (AOR). (nih.gov)
  • Medical therapy of cerebral aneurysms involves general supportive measures and prevention of complications for individuals who are in the periprocedural period or are poor surgical candidates. (medscape.com)
  • Following surgical or endovascular aneurysm treatment, blood pressure is maintained at higher levels to diminish complications associated with vasospasm. (medscape.com)
  • Prediction, pattern recognition and modelling of complications post-endovascular infra renal aneurysm repair by artificial intelligence. (cdc.gov)
  • Unfortunately, the physiologic mechanism of these serious procedure-related complications, such as instent stenosis or subacute in stent thrombosis after stenting and coiling of aneurysms, and their influence on overall long-term outcomes is unknown. (neurointervention.org)
  • Complication Avoidance: Tips and tricks to avoid complications in the treatment of brain aneurysms. (intechopen.com)
  • Although the initial technical and clinical results of Solitaire stent-assisted coiling of aneurysms was reported to be encouraging in recent reports, we had encountered higher thromboembolic and hemorrhagic complications in our patients. (neurologyindia.com)
Retreatment rates2
  • However, the occlusion rates seem rather low and the retreatment rates rather high compared to other treatment methods. (springer.com)
  • A recent meta-analysis published in World Neurosurgery found that COMANECI is associated with lower hemorrhagic and thromboembolic complication rates, higher complete occlusion rates, and similar residual retreatment rates than stent-assisted and balloon-assisted coiling techniques. (novumpr.nl)
Recurrence6
  • Aneurysm treatment by intrasaccular packing has been associated with a relatively high rate of recurrence. (ajnr.org)
  • Subsequently, all patients with an aneurysm remnant or recurrence of the target aneurysm retreated with microsurgical clipping were identified. (springer.com)
  • WEB treatment of acutely ruptured aneurysms results in high adequate occlusion rates, low perioperative complication rates, no rebleeding, and low recurrence requiring retreatment. (bmj.com)
  • Simultaneously, previous studies indicated that the stent-assisted coiling (SAC) technique was associated with a higher complete occlusion rate and lower recurrence rate at follow-up compared with coiling alone (CA) in ruptured intracranial aneurysms ( 7 , 8 ). (frontiersin.org)
  • However, studies on aneurysm occlusion, recurrence, and procedural complication rates of SAC treatment for ruptured tiny intracranial aneurysms were limited and heterogeneous ( 9 , 10 ). (frontiersin.org)
  • During follow-up we did not detect any aneurysm recurrence or haemorrhage. (uni-tuebingen.de)
Vessel7
  • An aneurysm is an abnormal local dilatation in the wall of a blood vessel. (medscape.com)
  • These are true aneurysms-that is, they are dilatations of a vascular lumen caused by weakness of all vessel-wall layers. (medscape.com)
  • Flow diverters can be placed in the parent vessel or within the aneurysm, which are called intrasaccular flow diverters. (wikipedia.org)
  • Most saccular or intracranial berry aneurysms were once thought to be congenital in origin, arising from focal defects in the media and gradually developing over a period of years as arterial pressure first weakens and subsequently balloons out the vessel wall. (medscape.com)
  • The absence of metallic mesh in the aneurysm's parent vessel lumen obviates the need for potent antiplatelet therapy, making this device appealing for acutely ruptured aneurysms not amenable to clipping or coiling. (bmj.com)
  • Preoperative trail balloon occlusion can help determine the patients' tolerance of temporary occlusion or if permanent vessel sacrifice is an option. (elsevierpure.com)
  • The functional prognosis of mechanical thrombectomy (MT) for mild acute ischemic stroke (AIS) with large-vessel occlusion (LVO) is controversial. (karger.com)
Saccular aneurysms4
  • Saccular aneurysms are rounded berrylike outpouchings that arise from arterial bifurcation points, most commonly in the circle of Willis (see the image below). (medscape.com)
  • Common locations of cerebral saccular aneurysms. (medscape.com)
  • Less common causes of saccular aneurysms include trauma, infection, tumor, drug abuse (cocaine), and high-flow states associated with AVMs or fistulae. (medscape.com)
  • BackgroundIntracranial fusiform aneurysms are less common than saccular aneurysms, but are associated with higher mortality and morbidity. (journaltocs.ac.uk)
Pipeline Embolization Device1
  • Few prospective studies exist evaluating the safety and efficacy of the Pipeline Embolization Device (PED) in the treatment of intracranial aneurysms. (nih.gov)
Clinical7
  • In the present study, the clinical and radiologic outcomes of unruptured intracranial vertebrobasilar dissecting aneurysms with brain stem compression based on different treatment modalities were evaluated. (ajnr.org)
  • Treatment decisions should be based on the clinical status of the patient, vascular anatomy of the aneurysm, and surgical or endovascular considerations. (medscape.com)
  • More recently, the data from the prospective "CLinical Assessment of WEB device in Ruptured aneurYSms" (CLARYS) study have been published [ 34 ]. (springer.com)
  • We conducted a prospective study to investigate the clinical and radiological outcome in a surgical case series of 176 patients with 203 unruptured intracranial aneurysms (UIA). (neurosurgery-blog.com)
  • Before treatment, the clinical status was assessed using the Glasgow Coma Scale (GCS)[ 43 ] in patients with nonruptured aneurysms and the Hunt and Kosnik scale for ruptured. (surgicalneurologyint.com)
  • Prediction of abdominal aortic aneurysm growth by artificial intelligence taking into account clinical, biologic, morphologic, and biomechanical variables. (cdc.gov)
  • Stability Assessment of Intracranial Aneurysms Using Machine Learning Based on Clinical and Morphological Features. (cdc.gov)
Giant aneurysms1
  • All giant aneurysms treated with PED alone were demonstrated by follow-up cross-sectional imaging to have involuted by 6 months. (ajnr.org)
Vascular5
  • Although genetic conditions are associated with increased risk of aneurysm development (see below), most intracranial aneurysms probably result from hemodynamically induced degenerative vascular injury. (medscape.com)
  • Other noninvasive imaging modalities have been developed for imaging the intracranial vessels and detecting aneurysms or other vascular pathology. (hindawi.com)
  • The common causes of intracranial aneurysm include hemodynamically induced or degenerative vascular injury, atherosclerosis (typically leading to fusiform aneurysms), underlying vasculopathy (eg, fibromuscular dysplasia), and high-flow states, as in arteriovenous malformation (AVM) and fistula. (medscape.com)
  • CT Circle of Willis demonstrates the vascular anatomy of the intracranial vessels for possible occlusion or aneurysms. (medical.canon)
  • 15%) followed by 2 cases of vascular obliteration (AICA/VA). In conclusion endovascular reconstruction using a FD represents a modern and e ective treatment in those aneurysms that are not suitable for conventional interventional or surgical treatment. (uni-tuebingen.de)
Embolization of intracranial1
  • Endovascular embolization of intracranial aneurysms has emerged as a viable and sometimes preferable method of treatment of intracranial aneurysms as demonstrated in the International Subarachnoid Aneurysm Trial (ISAT). (surgicalneurologyint.com)
Safety and efficacy2
  • This study aims to compare the safety and efficacy of stent-assisted coiling (SAC) with those of coiling alone (CA) for the treatment of ruptured tiny intracranial aneurysms. (frontiersin.org)
  • The safety and efficacy of SAC in the treatment of ruptured tiny intracranial aneurysms need to be further investigated. (frontiersin.org)
Unruptured and ruptured1
  • Since its approval by the US Food and Drug Administration (FDA) in 2018, the flow disruptor Woven EndoBridge (WEB) device has become increasingly popular for the endovascular treatment of unruptured and ruptured cerebral aneurysms. (springer.com)
Multicenter2
  • We performed a multicenter study prospectively evaluating patients with unruptured intracranial aneurysms treated with PED. (nih.gov)
  • Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6?Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study. (jefferson.edu)
Patients with ruptured3
  • Among patients with ruptured aneurysms, 6.2-15.1% are tiny intracranial aneurysms ( 2 , 3 ). (frontiersin.org)
  • International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. (ox.ac.uk)
  • METHODS: 2143 patients with ruptured intracranial aneurysms, who were admitted to 42 neurosurgical centres, mainly in the UK and Europe, took part in the trial. (ox.ac.uk)
Ischemic stroke1
  • The outcomes were statistically comparable between EC and NC for both ruptured and unruptured IA, except for a lower incidence of ischemic stroke in patients undergoing EC for ruptured aneurysms (OR 0.12, 95% CI 0.02 to 0.84).ConclusionsMost pregnant and postpartum patients are treated with EC for both ruptured and unruptured IA. (journaltocs.ac.uk)
Ruptured or unruptured aneurysm2
  • There were no statistically significant differences in the baseline characteristics between patients undergoing EC versus NC for either ruptured or unruptured aneurysm groups. (journaltocs.ac.uk)
  • Patients aged 21-90 years with a ruptured or unruptured aneurysm 3-15 mm in size were eligible for enrollment. (elsevierpure.com)
Posterior4
  • 2 deaths were related to the aneurysms (3.4%) - one ruptured dissecting MCA aneurysm, and one giant partially thrombosed posterior circulation aneurysm. (bvsalud.org)
  • MATERIALS AND METHODS: At 24 centers, 165 patients with 190 intracranial aneurysms of the anterior and posterior circulations were enrolled. (umassmed.edu)
  • Morbidity occurred in 4% and 7.4% of patients treated for aneurysms of the anterior and posterior circulation, respectively. (umassmed.edu)
  • Neurologic death during follow-up was observed in 1.6% and 7.4% of patients with treated intracranial aneurysms of the anterior and posterior circulation, respectively. (umassmed.edu)
Basilar1
  • Scope and Contents Drawings and notes relating to a named patient's basilar aneurysm. (ed.ac.uk)
Abstract1
  • abstract = "Background and purpose: Recent studies have shown promising results regarding intracranial aneurysms treated with flow diverters. (edu.au)
Thromboembolic1
  • More recently, application of diffusion-weighted MRI has demonstrated silent thromboembolic events associated with endovascular treatment of unruptured cerebral aneurysms. (medscape.com)
Complete occlusion rates1
  • Furthermore, COMANECI demonstrated statistically better complete occlusion rates than SAC and equivalent rates to BAC. (novumpr.nl)
Treated aneurysms were included1
  • One hundred and ninety-one patients with 207 treated aneurysms were included in this registry. (nih.gov)
Management of unruptured2
  • The management of unruptured intracranial aneurysms is highly controversial. (medscape.com)
  • Future studies in the management of unruptured intracranial aneurysms may systematically account for the evolving technology of advanced endovascular approaches, detailed aneurysm morphology, novel neuroimaging correlates, ethnic and geographical variation, neurocognitive impairment following endovascular or surgical treatment, and quality-of-life issues. (medscape.com)
Neurosurgery1
  • Between February 2007 and July 2008, a total of 19 aneurysms in 18 patients were treated at the National Institute of Neurosurgery, Budapest. (ajnr.org)
Cerebrovascular Diseases1
  • Deep Learning in the Management of Intracranial Aneurysms and Cerebrovascular Diseases: A Review of the Current Literature. (cdc.gov)
Centers1
  • At most centers, general anesthesia (GA) has been preferred for endovascular treatment (EVT) of ruptured intracranial aneurysms (RIAs). (e-jnc.org)
Systematic Review2
  • Recent guidelines and an evidence-based systematic review of the literature have formulated recommendations for the care of patients with unruptured intracranial aneurysms, principally based on age, history, and aneurysm size. (medscape.com)
  • Detection of cerebral aneurysms using artificial intelligence: a systematic review and meta-analysis. (cdc.gov)
Stenosis or aneurysm1
Morphology1
  • The anatomical characterization and morphology of unruptured aneurysms are not readily standardized, however. (medscape.com)
Vessels3
  • The use of intravenous contrast media is necessary for the identification of blood vessels and provides accurate information regarding the location, the size, and the shape of an aneurysm, as well as the presence of multiple aneurysms. (hindawi.com)
  • Notes = Abnormal outpouching in the wall of intracranial blood vessels. (ed.ac.uk)
  • vasculitis lead to occlusion of the vessels genital ulcerations, unilateral oedema or aneurysm formation [ 7 ]. (who.int)
Polycystic kidney2
  • Autosomal dominant polycystic kidney disease (ADPKD) is by far the most common genetic abnormality associated with intracranial aneurysms, with an estimated 5-40% of ADPKD patients harboring such lesions. (medscape.com)
  • These are patients with polycystic kidney disease, Marfan syndrome, coarctation of the aorta, fibromuscular dysplasia, family history of saccular aneurysm, and Ehlers-Danlos syndrome. (hindawi.com)
Flow diversion1
  • Intrasaccular flow disruption describes an endovascular treatment method, where in contrast to flow diversion, the device is directly placed into the aneurysm sac [ 28 ]. (springer.com)