• claudins
  • Many seminal discoveries have been published in the journal, including the first descriptions of numerous cellular functions and structures, such as the secretory pathway, mitochondrial and chloroplast DNA, microtubules, intermediate filaments, tight junctions (including occludins and claudins), adherens junctions, and cadherins. (wikipedia.org)
  • mice
  • A) Occludin, ZO-1 and claudin-5 expression in sham group, NS and metformin-treated mice at 3 days following tMCAO. (nih.gov)
  • The animal model for SAH is well established, and numerous studies are reported in mice [ 5 ]. (hindawi.com)
  • Adult ICR male mice ( n = 118) underwent 90-min middle cerebral artery occlusion and received 2 × 10 5 mesenchymal stem cell transplantation. (biomedcentral.com)
  • Mice were exposed to 1.2 g/m 3 1,2-DCE for 3.5 h per day for 1, 2, or 3 days, namely group A, B, and C. Na + -K + -ATPase and Ca 2+ -ATPase activity, ATP and lactic acid content, intracellular free Ca 2+ concentration and ZO-1 and occludin expression in the brain were measured. (frontiersin.org)
  • Furthermore, studies in which mice were deprived of occludin expression showed morphological stability in several epithelial tissues but also found chronic inflammation and hyperplasia in the gastric epithelium, calcification in the brain, testicular atrophy, loss of cytoplasmic granules in straited duct cells of salivary gland, and thinning of the compact bone. (wikipedia.org)
  • The phenotypical response of these mice to the lack of occludin suggest that the function of occludin is more complex than thought and requires more work. (wikipedia.org)
  • Mice that are deficient in claudin-2 have reduced reabsorption of Na+ in the proximal tubule, consistent with a role in paracellular transport. (wikipedia.org)
  • kidney
  • 2002).[supplied by OMIM] Claudin-2 is expressed in cation-leaky epithelia such as that of the kidney proximal tubule. (wikipedia.org)