Nitrate reductase (NADPH) (EC 1.7.1.3, assimilatory nitrate reductase, assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase, NADPH-nitrate reductase, assimilatory NADPH-nitrate reductase, triphosphopyridine nucleotide-nitrate reductase, NADPH:nitrate reductase, nitrate reductase (NADPH2), NADPH2:nitrate oxidoreductase) is an enzyme with systematic name nitrite:NADP+ oxidoreductase. (wikipedia.org)
This enzyme catalises the following chemical reaction nitrite + NADP+ + H2O ⇌ {\displaystyle \rightleftharpoons } nitrate + NADPH + H+ Nitrate reductase is an iron-sulfur molybdenum flavoprotein. (wikipedia.org)
An enzyme that catalyzes the oxidation of nitrite to nitrate in the presence of NADP+. (bvsalud.org)
The behaviour of nitrate reductase preparations during fractionation whether from P. sepia grown with KNO 3 or with NH 4 Cl suggests that the enzyme is the same from both sources. (microbiologyresearch.org)
In order to examine the function of the enzyme, the structure of NADH-cytochrome b(5) reductase from human erythrocytes has been determined and refined by X-ray crystallography. (nih.gov)
Under certain conditions (NH 4 NO 3 medium, 10%, v/v, O 2 in N 2 ) molybdenum (10 μ g./l.) depressed the nitrate reductase activity, but this effect was annulled by repeated subcultivation in molybdenum-deficient medium. (microbiologyresearch.org)
On the basis of its amino acid sequence, transhydroxylase can be classified as a member of the dimethylsulfoxide reductase family, whereas classification of the tungsten/molybdenum-containing acetylene hydratase has to await the determination of its amino acid sequence. (studyres.com)
Cytochrome4
Erythrocyte NADH-cytochrome b(5) reductase reduces methaemoglobin to functional haemoglobin. (nih.gov)
The molecular structure was compared with those of rat NADH-cytochrome b(5) reductase and corn nitrate reductase. (nih.gov)
A model of the complex between cytochrome b(5) and the human reductase has been built and compared with that of the haem-containing domain of the nitrate reductase molecule. (nih.gov)
The interaction between cytochrome b(5) and the human reductase differs from that of the nitrate reductase because of differences in the amino-acid sequences. (nih.gov)
Mechanism1
His current research interests focus on the identification of new antimicrobial therapies and unravel the molecular mechanism underlying the transcripcional regulation of bacterial ribonucleotide reductase genes. (ibecbarcelona.eu)
Influence1
The structures around 15 mutation sites of the human reductase have been examined for the influence of residue substitutions using the program ROTAMER. (nih.gov)
Structure1
The human reductase resembles the rat reductase in overall structure as well as in many side chains. (nih.gov)
Effect2
SUMMARY: The effect of cultural conditions on the growth and nitrate reductase activity of a bacterium, now identified as Photobacterium sepia , were examined. (microbiologyresearch.org)