• analysis
  • Molecular Analysis of Hereditary Nonpolyposis Colorectal Cancer in the United States: High Mutation Detection Rate Among Clinically Selected Families and Characterization of an American Founder Genomic Deletion of the MSH2 Gene American Journal of Human Genetics. (jove.com)
  • DECIPHER is a web-based resource and database of genomic variation data from analysis of patient DNA. (wikipedia.org)
  • This method can rapidly amplify minute amounts of DNA samples to a reasonable quantity for genomic analysis. (wikipedia.org)
  • Due to its strand displacement during amplification, the amplified DNA has sufficient coverage of the source DNA molecules, which provides high quality product for genomic analysis. (wikipedia.org)
  • Gene order evolution and genomic analysis of the model eukaryote, Saccharomyces cerevisiae, and other yeast species (PhD thesis). (wikipedia.org)
  • Variants
  • As only a relatively small proportion of the CNV regions overlap with regions found in other studies, the current total of more than 6,000 CNVs detailed in the Database of Genomic Variants ( http://projects.tcag.ca/variation/ ) is most likely an underestimate. (pubmedcentralcanada.ca)
  • protein
  • Cyanines dyes are usually synthesized from 2, 3, 5 or 7 methine structures with reactive groups on either one or both of the nitrogen side chains so that they can be chemically linked to either nucleic acids or protein molecules. (wikipedia.org)
  • method
  • Therefore, a more efficient non-sequence-specific method to amplify minute amounts of DNA is necessary, especially in single cell genomic studies. (wikipedia.org)
  • differences
  • However, comparative studies in other coral species are imperative to provide insight into the molecular differences between coral species and to determine the extent to which previous findings can be generalized. (biomedcentral.com)
  • The aim of this technique is to quickly and efficiently compare two genomic DNA samples arising from two sources, which are most often closely related, because it is suspected that they contain differences in terms of either gains or losses of either whole chromosomes or subchromosomal regions (a portion of a whole chromosome). (wikipedia.org)
  • different
  • The authors painted a series of individual human chromosomes from a DNA library with two different fluorophores in different proportions to test the technique, and also applied CGH to genomic DNA from patients affected with either Downs syndrome or T-cell prolymphocytic leukemia as well as cells of a renal papillary carcinoma cell line. (wikipedia.org)
  • The results of the study emphasize the need for quality control of the nucleic acid extracts with standardised methods to prevent false negative results and to allow data comparison among different diagnostic laboratories. (pubmedcentralcanada.ca)
  • single cell
  • A major drawback of genomic profiling for embryo quality is that the results generally rely on the assessment of a single cell, PGP has inherent limitations as the tested cell may not be representative of the embryo because of mosaicism. (wikipedia.org)
  • either
  • The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism. (google.com.au)
  • reference
  • By use of aCGH, DNA derived from tumor tissue can be compared with reference DNA, e.g., normal whole blood DNA, and genomic imbalances can effectively be investigated. (biomedcentral.com)
  • result
  • He is best known for his discovery that the genome of the yeast Saccharomyces cerevisiae underwent complete genome duplication about 100 million years ago, an event that is now known to be the result of hybridization between two divergent species. (wikipedia.org)