• genome
  • The cloning and sequencing of the complete genome of Norovirus genus has resulted in the development of molecular detection methods. (news-medical.net)
  • Like all noroviruses, MNV has a linear, non-segmented, positive-sense RNA genome of approximately 7.5 kbp, encoding a large polyprotein which is cleaved into six smaller non-structural proteins (NS1/2 to NS7) by the viral 3C-like protease (NS6), a major structural protein (VP1) of about 58~60 kDa and a minor capsid protein (VP2). (wikipedia.org)
  • Phylogenetic prediction of cis-acting elements: a cre-like sequence in Norovirus genome? (wikipedia.org)
  • capsid
  • Some examples are norovirus GII/Hu/US/2010/GII.P12-GII.12/HS206norovirus,norovirus GII/Hu/GB/2010/GII.P4_GII.4_NewOrleans2009/London48, or if only the capsid sequence is known: norovirus GI/Hu/AU/2012/GII.4 Sydney/Melbourne456. (news-medical.net)
  • This current study was a continuation of an earlier project conducted at the National Institutes of Health in the United States, where they discovered that citrate from a commercial company could bind to the norovirus capsid protein. (dkfz.de)
  • genogroup
  • Correct classification is important particularly for noroviruses belonging to genogroup II, genotype 4 (GII.4), due to the emergence of new pandemic GII.4 variants. (news-medical.net)
  • The strain name should include the organism (norovirus GI-VI), host (human, porcine, bovine, etc.), country code (ISO), year of sampling, genogroup and genotype and variant name (city, if necessary followed by a serial number). (news-medical.net)
  • prevention
  • The availability of more sensitive diagnostic methods has radically changed our appreciation of the epidemiology of norovirus disease, which resulted in strategies for prevention and treatment of this easily transmitted viral agent. (news-medical.net)
  • spreads
  • Norovirus is a germ that spreads quickly and easily. (cdc.gov)
  • This short video explains what norovirus is, how it spreads, and how you can protect yourself and loved ones from getting it. (cdc.gov)
  • Norovirus spreads quickly. (cdc.gov)
  • Norovirus spreads quickly from person to person in enclosed places like nursing homes, daycare centers, schools, and cruise ships. (cdc.gov)
  • The notoriety of norovirus comes from the ease with which it spreads from one person to another: You can catch it by ingesting food or drink that's been contaminated, or by touching any contaminated surface, then touching your nose, mouth or eyes. (livescience.com)
  • severe
  • Ms Hewitt said the emergence of new strain prompted a warning for healthcare institutions to be prepared for a severe norovirus season with the rise of the Sydney-2012 variant. (nzherald.co.nz)
  • cases
  • There were 87 cases of norovirus in October and November last year, compared with 14 in 2011 and 23 in 2010, ESR senior scientist Joanne Hewitt said. (nzherald.co.nz)
  • Norovirus result in about 685 million cases of disease and 200,000 deaths globally a year. (wikipedia.org)
  • sequence
  • In addition to these proteins, MNV is unique amongst the noroviruses in possessing an additional fourth open reading frame overlapping the VP1 coding sequence. (wikipedia.org)
  • recover
  • If you have been infected with norovirus, do not prepare food for others for at least two days after you recover, the CDC recommends. (livescience.com)
  • deaths
  • CDC estimates that each year in the United States norovirus causes 19 to 21 million illnesses, 56,000 to 71,000 hospitalizations, and 570 to 800 deaths. (cdc.gov)
  • Health
  • Christopher Beveridge, manager of environmental health for the district health unit, said Thursday that norovirus was found in a stool sample from a patient admitted to hospital. (cbc.ca)
  • days
  • Although having norovirus can be unpleasant, it is not usually dangerous and most who contract it make a full recovery within two to three days. (wikipedia.org)
  • found
  • Some older observations found that fruit extracts, such as orange or pomegranate juice, could reduce the infectivity of surrogate noroviruses. (dkfz.de)
  • surfaces
  • The combination of cleaning and disinfecting surfaces is usually effective at removing contamination, although some pathogens such as norovirus have an apparent resistance to these techniques. (wikipedia.org)