• skin
  • Keratinocytes in plaques from 18 psoriasis patients were more intensely stained than those from normal skin. (rupress.org)
  • Differentiated keratinocytes secrete keratin proteins which contribute to the formation of an extracellular matrix and is an integral part of the skin barrier function. (wikipedia.org)
  • In normal skin, the rate of keratinocyte production equals the rate of loss, taking about two weeks for a cell to journey from the stratum basale to the top of the stratum granulosum, and an additional four weeks to cross the stratum corneum. (wikipedia.org)
  • protein
  • Baden HP, Kubilus J, Wolman SR, Steinberg ML, Phillips SB, Kvedar JC (1987) The NM 1 keratinocyte line is cytogenetically and biologically stable and exhibits a unique structural protein. (springer.com)
  • expression
  • Gilmour continued her research at The Wistar Institute in Philadelphia, Pennsylvania, first as postdoctoral fellow (1984 to 1987) and then as research associate (1988 to 1990 While at Wistar, she began her work in characterizing the regulation and expression of ornithine decarboxylase (ODC) in both normal and tumor tissue. (wikipedia.org)
  • individuals
  • The plasma concentration reached a steady state on Day 5 of repeated administration study when nadifloxacin 1% cream was applied at 5 g twice daily to normal healthy individuals for a period of 7 days. (wikipedia.org)
  • generally
  • In these patients, Na+ ion concentrations can greatly increase (up to 180 mmol/L). In people who have hyperhidrosis, the sweat glands (eccrine glands in particular) overreact to stimuli and are just generally overactive, producing more sweat than normal. (wikipedia.org)
  • free
  • spinous layer (stratum spinosum) Keratinocytes become connected through desmosomes and start produce lamellar bodies, from within the Golgi, enriched in polar lipids, glycosphingolipids, free sterols, phospholipids and catabolic enzymes. (wikipedia.org)