• The elements were evaluated by the total number of peripheral leukocyte, granulocyte and lymphocyte ratio and lymphocyte subsets. (scirp.org)
  • The number of leukocyte subsets, granulocyte and lymphocyte were also regulated by dose dependent manner. (scirp.org)
  • The purpose of this study was to determine the effects of increased training via cross-training (run + cycle) and run training on circulating leukocyte subsets. (nih.gov)
  • After initiation of PF-00547659 anti-MAdCAM-1 therapy, there was a small and non-significant increase in the numbers of overall CSF leukocytes, and in lymphocyte subsets (CD3 +, CD4 +, and CD8 + T cells). (elsevierpure.com)
  • Automated identification of leukocyte subsets improves standardization of database-guided expert-supervised diagnostic orientation in acute leukemia: a EuroFlow study. (bvsalud.org)
  • Of the 8 plasma membrane receptors for complement, only deficiencies of CR3 and CR4 due to CD18 deficiency have been described, known as leukocyte adhesion deficiency (LAD) type 1 . (medscape.com)
  • Leukocyte adhesion deficiency results from an adhesion molecule defect that causes granulocyte and lymphocyte dysfunction and recurrent soft-tissue infections. (msdmanuals.com)
  • Manifestations of leukocyte adhesion deficiency usually begin in infancy. (msdmanuals.com)
  • Diagnosis of leukocyte adhesion deficiency is by detecting absence or severe deficiency of adhesive glycoproteins on the surface of WBCs using monoclonal antibodies (eg, anti-CD11, anti-CD18) and flow cytometry. (msdmanuals.com)
  • Leukocyte adhesion deficiency type I is caused by a mutation in the common chain of the β2 integrin family CD18. (lu.se)
  • Purpose: Leukocyte telomere length has gained attention as a marker of oxidative damage and age-related diseases, including cancer. (aacrjournals.org)
  • We hypothesize that leukocyte telomere length might be able to predict future risk of cancer and examined this in a cohort of patients with Barrett's esophagus, who are at increased risk of esophageal adenocarcinoma and thus were enrolled in a long-term cancer surveillance program. (aacrjournals.org)
  • Leukocyte telomere length hazard ratios (HR) for risk of esophageal adenocarcinoma were calculated using multivariate Cox models. (aacrjournals.org)
  • Family members without TERT mutations have a shorter mean telomere length than normal, demonstrating epigenetic inheritance of shortened telomere lengths in the absence of an inherited TERT mutation. (nih.gov)
  • leukocytes characterised by the presence of differently staining granules in their cytoplasm when viewed under light microscopy. (wikidoc.org)
  • leukocytes characterized by the absence of granules in their cytoplasm . (wikidoc.org)
  • As the number of cells increases, the proportion of immature cells usually rises, perhaps because the demands on the leukocyte-producing tissues in the bone marrow have increased to the point at which there is an insufficient number of mature cells for delivery into the circulation . (britannica.com)
  • Several different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a hematopoietic stem cell . (wikidoc.org)
  • Decreased WBC count, leukopenia, is seen when supply is depleted by infection or treatment such as chemotherapy or radiation therapy, or when a hematopoietic stem cell abnormality does not allow normal growth/maturation within the bone marrow, such as myelodysplastic syndrome or leukemia. (medscape.com)
  • he said that spoken voices sounded muffled, and he leukocytes/µL (100% lymphocytes). (cdc.gov)
  • In a normal person the immune system (the T lymphocytes, those that mature in the thymus , in particular) keeps the latent viruses in check. (britannica.com)
  • The white blood cells (leukocytes) are further divided into phagocytes or myeloid (neutrophils, eosinophils, basophils, monocytes) and immunocytes or lymphoid (lymphocytes). (medscape.com)
  • Neutrophils constitute 50 to 70% of total leukocytes and form the first line of defense against bacteria and fungi, according to studies . (steptohealth.com)
  • The effect of chemotherapeutic agents - cytosine arabinoside, methotrexate, procarbazine, vinblastine and vincristine - generally applied in the treatment of human cancer were tested on the motility of polymorphonuclear leukocytes. (karger.com)
  • Microscopic cervicitis (≥10 polymorphonuclear leukocytes/epithelial cell) and normal (predominantly lactobacillary) microbiota were the most frequent findings in the samples in which the pathogens were detected alone or in multiple infections, except for samples with Trichomonas vaginalis in which the coccobacillary microbiota was the most common. (hindawi.com)
  • 30 pmnl/hpf (polymorphonuclear leukocytes per high-powered field) on Gram stain [ 2 ]. (hindawi.com)
  • 20 µg/108 leukocytes) was deficient in 92.0% of asthmatics versus 8.0% of controls. (who.int)
  • Leukopenia is characterized by leukocyte counts that are abnormally low (below 4,000 per cubic millimetre). (britannica.com)
  • [1] In conditions such as leukemia the number of leukocytes is higher than normal, and in leukopenia this number is much lower. (wikidoc.org)
  • Oncolytic vesicular stomatitis virus (VSV) can be delivered intravenously to target primary and metastatic lesions, but the interaction between human peripheral blood leukocytes (PBLs) and VSV remains poorly understood. (karger.com)
  • Diagnosis can be confirmed through measurement of glucocerebrosidase activity in peripheral blood leukocytes. (medscape.com)
  • Studies state that normal white blood cell counts in adults are between 4,500 and 11,000 white blood cells per cubic millimeter of blood (mm³) . (steptohealth.com)
  • Remission means a child doesn't have any signs or symptoms of the condition, and blood cell counts are within normal limits. (medicinenet.com)
  • Leukocyte counts of 12,000 to 20,000 per cubic millimetre during infections are not unusual. (britannica.com)
  • The stated normal range for human blood counts varies between laboratories, but a neutrophil count of 2.5-7.5 x 10 9 /L is a standard normal range. (bionity.com)
  • People of African and Middle Eastern descent may have lower counts which are still normal. (bionity.com)
  • Vitamin C intake was assessed by 3-day dietary recall, and plasma and leukocyte vitamin C concentrations were measured colorimetrically. (who.int)
  • As the infection subsides, the number of younger forms and the total white cell count decrease and ultimately return to normal. (britannica.com)
  • When there is no infection, the neutrophil count is about twice the normal level. (lu.se)
  • Our observations suggest that normal numbers and composition of intrathecal leukocytes do not decrease the incidence of PLPH. (elsevierpure.com)
  • 2 ] in 1994 and is defined by the expression of a variety of cell surface antigens, including the stem cell marker CD34, the pan-leukocyte marker CD45, and monocyte markers CD14 and CD11. (ersjournals.com)
  • The type of leukocyte determines its specific functions within the immune system. (steptohealth.com)
  • White blood cells or leukocytes are cells of the immune system which defend the body against both infectious disease and foreign materials. (wikidoc.org)
  • B cells are normal but memory and switch B cells are low. (medscape.com)
  • The Innate Immunity Signal Transduction in Human Leukocytes is a research study to determine the response of immune cells from the bloodstream. (nih.gov)
  • Leukocytes are the most important defense cells in the human body. (steptohealth.com)
  • Leukocytes are the most abundant immune cells in the body. (steptohealth.com)
  • Leukocytes, or white blood cells, are a group of blood cells that actively participate in the innate and adaptive immune response of each person, according to different studies . (steptohealth.com)
  • They're the least abundant leukocytes, constituting between 0.4 and 1 % of white blood cells. (steptohealth.com)
  • Normal myeloid cells undergo differentiation to form leukocytes. (medicinenet.com)
  • There are some immature cells, but others are normal and function normally. (medicinenet.com)
  • The condition in which white cells are present in greater numbers than normal is termed leukocytosis . (britannica.com)
  • The physical properties of leukocytes, such as volume, conductivity, and granularity, may change due to activation, the presence of immature cells, or the presence of malignant leukocytes in leukemia. (wikidoc.org)
  • they account for 70% of all white blood cells (leukocytes). (bionity.com)
  • n = 45) samples analyzed with the ALOT was constructed, and served as a reference for the AGI tool to automatically identify normal cells . (bvsalud.org)
  • Populations not unequivocally identified as normal cells were labeled as checks and were classified by an expert. (bvsalud.org)
  • Problems start when leukemia cells become more numerous than normal cells and erythrocyte precursor cells5. (bvsalud.org)
  • Within normal limits intravenous drug use. (cdc.gov)
  • Elevated leukocytes and CRP level indicated prolonged intravenous antibiotic treatment course. (springer.com)
  • Hydration, with intravenous normal saline at a reasonable rate, is essential. (medscape.com)
  • The percentage of leukocytes can increase or decrease in response to a wide range of diseases, making their determination indispensable for the diagnosis and early treatment of many conditions. (steptohealth.com)
  • As a result, numerous authors have suggested an introduction of sperm DNA damage testing into the andrological laboratory workup as an independent tool as DNA fragmentation apart from normal sperm morphology appears to be a reliable and more robust parameter than conventional semen analysis due to its low biological variability and thus is a useful biomarker that should be implemented in any andrological diagnostic workup [ 19 - 21 ]. (hindawi.com)
  • The correct diagnosis and treatment of these patients depend on the knowledge of normal hemostasis mechanisms and the results of laboratory tests that evaluate these mechanisms. (bvsalud.org)
  • A white blood cell which appears 5,000 to 10,000 times in each cubic millimeter of normal human blood. (digitalnaturopath.com)
  • Eosinophilic leukocytosis, an increase in the number of eosinophilic leukocytes, is encountered in many allergic reactions and parasitic infections. (britannica.com)
  • i. of the uterus the process of reduction of the uterus to its normal nonpregnant size and state following childbirth. (theodora.com)
  • Floor heating system regulated total number of peripheral leukocyte. (scirp.org)
  • Total bilirubin = 2 times the normal value for each institution. (who.int)
  • Plasma and leukocyte vitamin C levels were significantly lower in the asthma group. (who.int)
  • and normal renal and liver function. (cdc.gov)
  • A finding of less than 15% of mean normal activity is diagnostic. (medscape.com)
  • For normal function, an activated PMN generates a certain concentration of reactive oxygen species (ROS). (scirp.org)
  • Une corrélation significative positive a été trouvée entre la vitamine C plasmatique et l'apport alimentaire en vitamine C. Le taux de vitamine C plasmatique et leucocytaire était significativement moins élevé dans le groupe des patients asthmatiques. (who.int)
  • Une étude a été menée dans des unités de soins intensifs en chirurgie pour adultes de l'hôpital universitaire de Zagazig, (Égypte) auprès de 25 patients atteints de septicémie, de 27 patients atteints d'une septicémie sévère et de 28 témoins. (who.int)
  • Glucosylceramide, the accumulated glycolipid, is primarily derived from the phagocytosis and degradation of senescent leukocytes and erythrocyte membranes. (medscape.com)
  • article nr. 55037C-1000 ML) and 10 µl freshest normal blood anticoagulated with 11 mM sodium citrate (within 30 min after withdrawal). (scirp.org)
  • The scientific term leukocyte directly reflects this description, derived from Greek leukos - white, and kytos - cell. (wikidoc.org)
  • A large body of evidence now implicates increased leukocyte-endothelial cell adhesion as a key early event in the development of diabetic retinopathy. (diabetesjournals.org)
  • We recently reported that raised activity of the glycosylating enzyme core 2 β 1,6- N -acetylglucosaminyltransferase (GlcNAc-T) through protein kinase C (PKC)β2-dependent phosphorylation plays a fundamental role in increased leukocyte-endothelial cell adhesion and capillary occlusion in retinopathy. (diabetesjournals.org)
  • The exact pathogenic mechanism by which capillary nonperfusion, as demonstrated by fluorescein angiography, occurs is still unclear, but recent experimental animal studies ( 3 - 5 ) demonstrate that increased leukocyte entrapment in retinal capillaries of diabetic rats is an early event associated with areas of capillary nonperfusion and the development of endothelial cell damage. (diabetesjournals.org)
  • A scanning electron microscope image of normal circulating human blood. (wikidoc.org)
  • Asthma is a chronic relapsing inflammatory study in Tehran with the hypothesis that disorder of the airways and a major health plasma and leukocyte vitamin C level are problem worldwide [ 1 ]. (who.int)