• allele
  • Using the amplification refractory mutagenesis system, two different reactions distinguished the presence of a guanine (normal E1u allele) from that of an adenine (Kalow E1k allele) at nucleotide 1615 within the coding sequences of the gene. (wikipedia.org)
  • The criterion is that the frequency of the least common morph is too high simply to be the result of new mutations or, as a rough guide, that it is greater than 1% (though that is far higher than any normal mutation rate for a single allele). (wikipedia.org)
  • That is, the presence of a single wild-type allele is sufficient to permit the production of the normal number of melanin granules. (wikipedia.org)
  • recessive
  • These were English Fallow, red eye, solid without ring German, red eye with ring Californian, similar to German, red eye with ring Californian, a near solid red eye type with rather fine grey markings Texas, a red eye with strong body colour He said all were recessive and produce normals if intermated. (wikipedia.org)
  • In the Recessive Pied the clear areas are very extensive and many Recessive Pieds are predominantly clear with quite small irregularly shaped areas of normal pigmentation. (wikipedia.org)
  • kidney
  • As soon as parent knows Walcott-Rallison syndrome is the source, treatment or therapy plans need to be drawn up along with frequent check ins to make sure kidney and liver functions are around normal and insulin therapy are working. (wikipedia.org)
  • metabolism
  • On the basis of genetic polymorphism a population may be divided into two groups namely extensive metabolizers (EMs) demonstrating normal metabolism of the drugs and poor metabolizers (PMs) demonstrating impaired metabolism of drugs due to the deficiency of CYPs. (redorbit.com)
  • The study of normal human metabolism and its alterations is central to the understanding and treatment of a variety of human diseases, including diabetes, metabolic syndrome, neurodegenerative disorders, and cancer. (embopress.org)
  • individuals
  • The number of CR1 molecules decreases with aging of erythrocytes in normal individuals and is also decreased in pathological conditions such as systemic lupus erythematosus (SLE), HIV infection, some haemolytic anaemia s and other conditions featuring immune complexes. (wikipedia.org)
  • Although
  • Although some normal responses to bacterial lipopolysaccharide (LPS) administration are observed (shivering and lethargy), these mice are resistant to LPS-induced lethality. (jax.org)
  • activity
  • Dibucaine inhibits normal butyrylcholinesterase activity, reducing the ability to convert butyrylcholine to its byproducts. (wikipedia.org)