• All participants underwent technetium-99 m sestamibi (99mTc-MIBI) scintigraphy and ankle-brachial index (ABI) examination. (bvsalud.org)
  • Plenar imaging for the evaluation of sensificity of myocardial perfusion scintigraphy with Technetium-99m sestamibi in coronary artery disease. (mil.pl)
  • Triggered by electrocardiogram (EKG) to obtain differential information about the heart in various parts of its cycle, gated myocardial SPECT can be used to obtain quantitative information about myocardial perfusion, thickness, and contractility of the myocardium during various parts of the cardiac cycle, and also to allow calculation of left ventricular ejection fraction, stroke volume, and cardiac output. (wikipedia.org)
  • Myocardial perfusion imaging (MPI) is a form of functional cardiac imaging, used for the diagnosis of ischemic heart disease. (wikipedia.org)
  • Transient ischemic dilation (TID) in the setting of abnormal stress-rest cardiac SPECT myocardial perfusion imaging (MPI) has been linked with increased cardiovascular risk. (snmjournals.org)
  • Transient ischemic dilation (TID) on stress SPECT myocardial perfusion imaging (MPI) is defined as the apparent presence of left ventricular (LV) dilation on poststress relative to rest images. (snmjournals.org)
  • 1 The basic principle of radionuclide MPI is to administer a radiopharmaceutical intravenously and image blood flow to the heart muscle (myocardial perfusion), both at rest and under stress. (cadth.ca)
  • 7 Viable myocardial cells take up the radionuclide tracer (either thallium isotope [ 201 TI] or isotope 99m Tc-labelled radiotracer) in proportion to blood flow. (cadth.ca)
  • The American Heart Association recommends that in nonemergency settings, patients should be informed of the risks (including those associated with radiation) and benefits involved in the use of cardiac CT scanning, radiopharmaceuticals, and fluoroscopy. (medscape.com)
  • Careful evaluation of the patient's history and physical examination (including signs of congestion, such as jugular venous distention [JVD]) can provide important information about the underlying cardiac abnormality in heart failure. (medscape.com)
  • 1 The American College of Cardiology/American Heart Association (ACC/AHA) 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery 3 stratify cardiac risk of non-cardiac surgery, according to procedure - vascular surgery is associated with the highest cardiac risk. (cadth.ca)
  • As with nuclear imaging for other cardiac indications, the relative distribution of the radionuclide allows for visualization of blood flow through the heart and gives information regarding the functional capacity of the heart. (cadth.ca)
  • Here we report the results of our studies on the possibility to detect in vivo and non-invasively malignant tumors that will become resistant to subsequent therapy using single-photon emission tomography and 99mTc-Sestamibi, a tumor-seeking agent currently used in clinical practice. (cnr.it)
  • [ 3 ] However, other studies and/or tests may be necessary to identify structural abnormalities or conditions that can lead to or exacerbate heart failure. (medscape.com)
  • It is the test of choice for patients with active chest pain, an ECG with no ischemic changes, and an initial negative troponin result, according to the American College of Radiology guidelines. (medscape.com)
  • Therefore, the corresponding radiopharmaceuticals have been a major focus, and some of them like 99m Tc-Annexin V, 18 F-ML-10, 18 F-CP18, and 18 F-ICMT-11 are currently under clinical investigations in Phase I/II or Phase II/III clinical trials on a wide scope of diseases. (oncotarget.com)
  • Our studies showed that both the uptake and efflux mechanisms of 99mTc-Sestamibi can be helpful for the non-invasive assessment of drug resistance in cancer. (cnr.it)
  • The CBC aids in the assessment of severe anemia, which may cause or aggravate heart failure. (medscape.com)
  • These noninvasive tests can be performed in an outpatient setting, in a physician's office, in a hospital, or in an observation unit, as well as for admitted inpatients. (medscape.com)
  • Congenital heart diseases (CHDs) are the most common major congenital anomaly at up to 28%1 and are responsible for 5.7% of all infant mortality.2. (annals.edu.sg)
  • In cases of severe heart failure, however, prolonged, rigid sodium restriction, coupled with intensive diuretic therapy and the inability to excrete water, may lead to dilutional hyponatremia, which occurs because of a substantial expansion of extracellular and intravascular fluid volume and a normal or increased level of total body sodium. (medscape.com)
  • Serum electrolyte values are generally within reference ranges in patients with mild to moderate heart failure before treatment. (medscape.com)
  • GTN can also be used alone or in combination with other agents to decrease the number of ischaemic episodes in patients with proven CAD or ischaemic cardiomyopathy with a high degree of effectiveness. (bmj.com)
  • Liga R, Colli A, Taggart DP, Boden WE, De Caterina R. Myocardial Revascularization in Patients With Ischemic Cardiomyopathy: For Whom and How. (bu.edu)
  • Nowadays, coronary computed tomography angiography (CCTA) has a role of paramount importance in the diagnostic algorithm of ischemic heart disease (IHD), both in stable coronary artery disease (CAD) and acute chest pain. (bvsalud.org)
  • My principal research interests include studies in stable ischemic heart disease, post-MI secondary prevention, acute coronary syndromes, and preventive cardiology. (bu.edu)
  • Marked ischemic ST-segment elevations in inferior limb leads (II, III, aVF) and laterally (V 6 ) suggestive of acute inferolateral MI, and prominent ST-segment depressions with upright T waves in V 1 -V 4 are consistent with associated acute posterior MI. (basicmedicalkey.com)
  • Lack of technetium-99m methoxyisobutylisonitrile ((99m) Tc-MIBI) uptake is consistently reported to predict poor response to subsequent chemotherapy in a variety of human malignant tumours. (cnr.it)