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  • results
  • CONCLUSIONS: These results suggest that chrysin-nitrofurantoin interactions occur in the small intestine in rats, but not in mice, possibly due to the higher levels of Bcrp expression in the small intestine in rats, compared with those in mice. (ualberta.ca)
  • Furadantin
  • The FDA-approved label for Furadantin includes a warning that cases of hemolytic anemia of the primaquine-sensitivity type have been induced by nitrofurantoin, presumably due to G6PD -deficiencies as have been linked to primaquine . (snpedia.com)
  • bacteria
  • however, the safety and effectiveness of nitrofurantoin in treating clinical infections due to these bacteria have not been established in adequate and well controlled clinical trials. (nih.gov)
  • The broad-based nature of this mode of action may explain the lack of acquired bacterial resistance to nitrofurantoin, as the necessary multiple and simultaneous mutations of the target macromolecules would likely be lethal to the bacteria. (nih.gov)
  • Treatment options for vancomycin-resistant E. faecalis include nitrofurantoin (in the case of uncomplicated UTIs), linezolid, and daptomycin, although ampicillin is preferred if the bacteria are susceptible. (wikipedia.org)
  • Another group of DNA inhibitors, including nitrofurantoin and metronidazole, act upon anaerobic bacteria. (wikipedia.org)
  • Microbiology
  • The efficacy of nitrofurantoin in treating UTIs combined with a low rate of bacterial resistance to this agent makes it one of the first-line agents for treating uncomplicated UTIs as recommended by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. (wikipedia.org)
  • Klebsiella
  • NOTE: Some strains of Enterobacter species and Klebsiella species are resistant to nitrofurantoin. (nih.gov)
  • Nitrofurantoin is an anti-infective agent that is FDA approved for the treatment of urinary tract infections when due to susceptible strains of Escherichia coli , enterococci , Staphylococcus aureus , and certain susceptible strains of Klebsiella and Enterobacter species. (wikidoc.org)
  • Nitrofurantoin has been shown to have good activity against: E. coli Staphylococcus saprophyticus Coagulase negative staphylococci Enterococcus faecalis Staphylococcus aureus Streptococcus agalactiae Citrobacter species Klebsiella species Bacillus subtilis species It is used in the treatment of infections caused by these organisms. (wikipedia.org)
  • treatment
  • The reaction can occur within hours of the start of treatment if the patient has previously received nitrofurantoin, or within a few days of starting nitrofurantoin for the first time. (medicinenet.com)
  • Nitrofurantoin is not recommended for the treatment of pyelonephritis, prostatitis and intra-abdominal abscess, because of extremely poor tissue penetration and low blood levels. (wikipedia.org)