• Nitric Oxide
  • Further, the nitric oxide inhibitor (NO), L-Nomega - nitro-Arginine Methyl Ester (L-NAME) 10 mg/kg totally inhibited the rise in medullary blood flow due to CCD-X. In vitro studies in isolated perfused kidneys (IPK) and in pressurised microvessels (PMV) confirmed the in vivo effect to cause vasoconstriction, which was inhibited by endothelin A and B antagonists. (wikipedia.org)