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  • Effects
  • Because the effectiveness of these agents has been based largely on improvement in subjective reporting of hot flashes, it is not clear whether benefits are due to physiological effects on hot flashes or due to improvements in mood or other related symptoms. (clinicaltrials.gov)
  • central
  • Anticholinergics are divided into three categories in accordance with their specific targets in the central and peripheral nervous system: antimuscarinic agents, ganglionic blockers, and neuromuscular blockers. (wikipedia.org)
  • Active
  • Active transport Releasing agent Bermingham DP, Blakely RD (October 2016). (wikipedia.org)
  • A small electric current is applied to an iontophoretic chamber placed on the skin, containing a charged active agent and its solvent vehicle. (wikipedia.org)
  • benzodiazepines
  • However, a systematic review concluded that compared with other anxiolytic agents (benzodiazepines and buspirone), hydroxyzine was equivalent in efficacy, acceptability, and tolerability, however there is insufficient evidence to recommend it as a treatment for generalised anxiety disorder due to the high risk of bias in the reviewed studies. (wikipedia.org)
  • For dentistry and obstetrics as well as other surgeries and procedures and acute pain situations like accidents, hydroxyzine is useful as a first-line anxiolytic and opioid adjunct because it lacks both antagonism and synergy with benzodiazepines and scopolamine, allowing either of these agents to be used simultaneously or later in the procedure if need be. (wikipedia.org)