NeuronsInsulinReceptor, InsulinNeurons, AfferentInsulin ResistanceMotor NeuronsScienceGlucoseTumor Necrosis Factor-alphaInsulin Receptor Substrate ProteinsTumor Markers, BiologicalTumor BurdenCell Line, TumorCells, CulturedInsulin, Long-ActingSignal TransductionTime FactorsHypoglycemic AgentsInsulin AntibodiesMice, Inbred C57BLAction PotentialsResearch PersonnelInsulin AntagonistsIslets of LangerhansWilms TumorRNA, MessengerImmunohistochemistryInsulin LisproNeoplasms, ExperimentalGenes, Tumor SuppressorDopaminergic NeuronsGlucose Tolerance TestTumor Suppressor Protein p53Carcinoid TumorMice, TransgenicDose-Response Relationship, DrugDiabetes Mellitus, Type 2Rats, WistarInsulin Infusion SystemsTumor Suppressor ProteinsGlucose Clamp TechniquePhosphorylationCell LineMice, KnockoutDisease Models, AnimalNerve Tissue ProteinsNeuroendocrine TumorsPatch-Clamp TechniquesGABAergic NeuronsElectrophysiologyInsulin AspartBrain NeoplasmsInsulin, IsophaneHistory, 20th CenturyAdipose TissueHippocampusHyperinsulinismTumor MicroenvironmentResearchMutationInsulin, Regular, PorkSynapsesBiomedical ResearchGanglia, SpinalAxonsLiverMolecular Sequence DataInsulin-Secreting CellsModels, BiologicalReverse Transcriptase Polymerase Chain ReactionMammary Neoplasms, ExperimentalCell SurvivalObesityCell ProliferationSensory Receptor CellsSynaptic TransmissionInsulinsDendritesElectric StimulationGene Expression RegulationGlucagonRats, Sprague-DawleyAnimals, NewbornNeoplasmsMembrane PotentialsBlotting, WesternOlfactory Receptor NeuronsNeovascularization, PathologicGene ExpressionTransfectionCerebral CortexSpinal CordCell DivisionMuscle, SkeletalCholinergic NeuronsC-PeptideFastingNobel PrizeInsulin, Regular, Humangamma-Aminobutyric Acid