Mitochondrial DynamicsMitochondriaMitochondrial ProteinsGTP PhosphohydrolasesNeurodegenerative DiseasesMitochondrial DegradationOrganelle ShapeDynaminsNerve DegenerationMitochondrial MembranesOptic Atrophy, Autosomal DominantMicrotubule-Associated ProteinsMitochondrial DiseasesNeuronsMembrane Potential, MitochondrialParkinson DiseaseMitochondrial SizeAutophagyProton IonophoresMembrane FusionQuinazolinonesModels, BiologicalUbiquitin-Protein LigasesAlzheimer DiseaseMutationDNA, MitochondrialApoptosisReactive Oxygen SpeciesNerve Tissue ProteinsCell DeathPantothenate Kinase-Associated NeurodegenerationOxidative StressCell RespirationCells, CulturedMembrane ProteinsMolecular Dynamics SimulationMice, TransgenicMicroscopy, Electron, TransmissionSignal TransductionBrainMitochondria, HeartHeLa CellsEnergy MetabolismGreen Fluorescent ProteinsMitochondrial Membrane Transport ProteinsMicroscopy, ConfocalDisease Models, AnimalAgingtau ProteinsDrosophila ProteinsCell LineAdenosine TriphosphateCytochromes cProtein KinasesProtein TransportMitochondria, MuscleGene Expression RegulationHeredodegenerative Disorders, Nervous SystemPopulation DynamicsMicrogliaRats, Sprague-DawleyNeuroprotective AgentsBlotting, Westernalpha-SynucleinProtein BindingTauopathiesMolecular Sequence DataAmyloid beta-PeptidesHuntington DiseaseFibroblastsDopaminergic Neurons