MicrogliaNerve DegenerationNeurodegenerative DiseasesNeuronsBrainPantothenate Kinase-Associated NeurodegenerationDisease Models, AnimalGliosisAstrocytesAlzheimer DiseaseAmyloid beta-PeptidesNeuroprotective AgentsMice, Transgenictau ProteinsCell DeathMice, Inbred C57BLCells, CulturedParkinson DiseaseHeredodegenerative Disorders, Nervous Systemalpha-SynucleinNeurogliaNerve Tissue ProteinsEncephalitisTauopathiesDopaminergic NeuronsHippocampusNeurotoxinsHuntington DiseaseCentral Nervous SystemSubstantia NigraMice, KnockoutGlial Fibrillary Acidic ProteinAnimals, NewbornImmunohistochemistryParkinsonian DisordersInflammationRats, Sprague-DawleyOxidative StressAmyloid beta-Protein PrecursorAmyotrophic Lateral SclerosisNeurotoxicity SyndromesCerebral CortexPlaque, AmyloidAgingDopamineMinocyclineNeurofibrillary TanglesMutationLipopolysaccharidesSignal TransductionInclusion Bodies1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineAnimals, Genetically ModifiedKainic AcidGene Expression RegulationApoptosisAutophagyAntigens, CD11bSpinal CordProteostasis DeficienciesSpinocerebellar AtaxiasMitochondriaPrion DiseasesMPTP PoisoningNiemann-Pick Disease, Type CNeuroaxonal DystrophiesCell SurvivalCorpus StriatumBlotting, WesternAnalysis of VarianceIron Metabolism DisordersMice, Neurologic MutantsSilver StainingBehavior, AnimalReactive Oxygen SpeciesMacrophagesTime FactorsCoculture TechniquesCell CountTrinucleotide Repeat ExpansionCytokinesPhenotypeMultiple SclerosisOligodendrogliaIn Situ Nick-End LabelingRats, WistarDrosophilaCerebellumPrimary Cell CultureAxonsRotarod Performance TestPeptide FragmentsInterleukin-1betaBrain InjuriesLewy BodiesRNA, MessengerLysosomal Storage Diseases, Nervous SystemPrionsFrontotemporal Lobar DegenerationRetinal Degeneration