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  • retinal nerve fiber
  • To investigate the reproducibility of peripapillary retinal nerve fiber layer thickness (RNFLT) measurements obtained with optical coherence tomography (OCT) in glaucoma patients both before and after a comprehensive ophthalmic examination including Goldmann applanation tonometry and pupillary dilation. (arvojournals.org)
  • Prior to examination and prior to instillation of any topical medications, the Stratus OCT was used to perform three consecutive scans of the peripapillary retinal nerve fiber layer (RNFL) of both eyes using the 3.4 mm Fast RNFL protocol. (arvojournals.org)
  • The purpose of this study was to cluster the test points of the combined 24-2 and 10-2 visual fields (VFs) and circumpapillary retinal nerve fiber layer thickness (cpRNFLT) sectors using explanatory factor analyses (EFAs). (arvojournals.org)
  • Retinal
  • Correlation between Axial Length and Retinal Nerve Fiber Layer Thickness in Myopic Eyes. (thefreedictionary.com)
  • 4,5 Apart from elevated intraocular pressure (IOP), various pressure independent factors represent the main risk factors for loss of retinal nerve fiber layer (RNFL) with subsequent glaucomatous damage in PXF syndrome. (thefreedictionary.com)
  • Optical coherence tomography (OCT) manufacturers graphically present circumpapillary retinal nerve fiber layer thickness (cpRNFLT) together with normative limits to support clinicians in diagnosing ophthalmic diseases. (spiedigitallibrary.org)
  • The sparing of this layer is important in the treatment of the disease as it is the basis for connecting retinal prostheses to the optic nerve, or implanting stem cells that could regenerate the lost photoreceptors. (wikipedia.org)
  • This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918) Walia S, Fishman GA, Edward DP, Lindeman M. Retinal nerve fiber layer defects in RP patients. (wikipedia.org)
  • PMID 17898300 Oishi A, Otani A, Sasahara M, Kurimoto M, Nakamura H, Kojima H, Yoshimura N. Retinal nerve fiber layer thickness in patients with retinitis pigmentosa. (wikipedia.org)
  • nociceptors
  • C fiber receptors include: C fiber nociceptors responsible for the second, burning pain C fiber warming specific receptors responsible for warmth ultra-slow histamine-selective C fibers responsible for itch tactile C fibers sensual touch includes CT fibres, also known as C low-threshold mechanoreceptors (CLTM), which are unmyelinated afferents found in human hairy skin, and have a low mechanical threshold (wikipedia.org)
  • neuropathic
  • Damage or injury to nerve fibers causes neuropathic pain . (wikipedia.org)
  • Pain in cancer can be produced by mechanical (e.g. pinching) or chemical (e.g. inflammation) stimulation of specialized pain-signalling nerve endings found in most parts of the body (called nociceptive pain), or it may be caused by diseased, damaged or compressed nerves, in which case it is called neuropathic pain. (wikipedia.org)
  • afferents
  • To investigate the role of small myelinated afferents in nonhistaminergic itch, we tested, in psychophysical studies in humans, the effect of a differential nerve block on itch produced by intradermal insertion of spicules from the pods of a cowhage plant ( Mucuna pruriens ). (jneurosci.org)
  • In electrophysiological recordings from primary afferents in the anesthetized monkey, we tested whether cowhage, histamine, or capsaicin activated high threshold A-fiber afferents. (jneurosci.org)
  • In the context of a given brain region, afferents are arriving fibers while efferents are exiting fibers. (wikipedia.org)
  • membrane
  • Osmotic and diffusion permeabilities ( P f and P d ) of invertebrate nerve fibers to tritiated water were measured to determine what water flux studies could reveal about "the nerve membrane" and to directly test the possibility of active transport of water into or out of invertebrate nerve fibers. (rupress.org)
  • We propose that calcium activated phospholipase A2 plays a central role in resealing of the ruptured nerve membrane. (sciencemag.org)
  • Damage
  • So, she went back to the drawing board and discovered that if she also used the laser to damage some skin cells in the tail fin, the nerves regenerated. (mdibl.org)
  • Rieger and colleagues went on discover that the opposite is also true: when they used a cancer chemotherapy drug to damage skin cells in a zebrafish tail fin, it contributed to the degeneration of the fin's nerve fibers . (mdibl.org)
  • Based on these findings, Rieger wants to see whether similar processes may be going on in the hands and feet of cancer patients who struggle with painful nerve damage, called peripheral neuropathy, caused by certain chemotherapy drugs, including taxanes and platinum compounds. (mdibl.org)
  • After bowel surgery, more than half of the patients suffer from irreparable nerve damage. (medicalxpress.com)
  • The cornea is the most densely innervated tissue in the body, so corneal nerve assessment is extremely sensitive for detecting small sensory nerve fiber damage as compared to other tests including measurement of intra-epidermal nerve fibers in the skin, notes lead investigator Joseph L. (thefreedictionary.com)
  • This study focuses on the use of Metanx® as the sole treatment for improving and reversing nerve damage in type 2 diabetic patients with peripheral neuropathy. (clinicaltrials.gov)
  • Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss. (wikipedia.org)
  • Conversely, optic nerve damage may occur with normal pressure, known as normal-tension glaucoma. (wikipedia.org)
  • In English, the word was used as early as 1587 but did not become commonly used until after 1850, when the development of the ophthalmoscope allowed people to see the optic nerve damage. (wikipedia.org)
  • degeneration
  • This eccentric training method is especially important for individuals with chronic Achilles tendinosis which is classified as the degeneration of collagen fibers. (wikipedia.org)
  • stimulus
  • A touch or painful stimulus, for example, creates a sensation in the brain only after information about the stimulus travels there via afferent nerve pathways. (wikipedia.org)
  • cells
  • It consists of axons of more than one million nerve cells and is very important for voluntary control of the muscles of the body, arms and legs. (wingsforlife.com)
  • The growth factor IGF1 (Insulin like growth factor) influences and promotes the development and growth of nerve cells. (wingsforlife.com)
  • Another notable structure is the medulla of the adrenal gland, where chromaffin cells function as modified post-ganglionic nerves. (wikipedia.org)
  • Most of the fibers are centripetal, and are the direct continuations of the axis-cylinder processes of the cells of the ganglionic layer, but a few of them are centrifugal and ramify in the inner plexiform and inner nuclear layers, where they end in enlarged extremities. (wikipedia.org)
  • itch
  • Magerl, 1991 ) suggest that activity in thinly myelinated Aδ-fibers may contribute to the sensation of itch. (jneurosci.org)
  • However, rigorous psychophysical and neurophysiological evidence for a functional role of A-fibers in the mediation of nonhistaminergic itch in primates is lacking. (jneurosci.org)
  • In addition, it has not been explored if C- and A-fibers mediate different qualities of the itch percept. (jneurosci.org)
  • In psychophysical experiments, we used a selective conduction block of myelinated fibers to test the hypothesis that activity in A-fibers contributes to cowhage-induced itch. (jneurosci.org)
  • branch
  • Fourteen subjects (7 female, 7 male) were each given two to four control tests with cowhage on the dorsum of the hand within the anticipated autonomous zone of the superficial branch of the radial nerve (in the region of the interosseus muscle and extending to the base of the thumb and adjacent two fingers). (jneurosci.org)
  • A 2.5-cm-wide rubber band was draped over the wrist directly over the superficial branch of the radial nerve. (jneurosci.org)
  • The Martin-Gruber Anastomosis (or Martin-Gruber Connection) is a communicating nerve branch between the median nerve and the ulnar nerve in the forearm. (wikipedia.org)
  • Each sweat gland receives several nerve fibers that branch out into bands of one or more axons and encircle the individual tubules of the secretory coil. (wikipedia.org)
  • It is controlled by the deep perineal branch of the pudendal nerve. (wikipedia.org)
  • experiments
  • In experiments where nerve injury is caused but nearby C fibers remain intact, increased spontaneous activity in the C fibers is observed. (wikipedia.org)
  • The experiments started at the University of Cambridge, beginning in 1935 with frog sciatic nerve, and soon after they continued their work using squid giant axons at the Marine Biological Association Laboratory in Plymouth. (wikipedia.org)
  • regeneration
  • The nerve regeneration was occurring in tissue being spontaneously formed to replace a section of a young zebrafish's tail fin that had been lopped off 3 days earlier. (mdibl.org)
  • Along with other tools, Rieger is using such imaging to explore how the processes of nerve regeneration and wound healing are coordinated. (mdibl.org)
  • brain
  • The MRI results showed that the football players developed changes in the corpus callosum, a critically important band of nerve fibers that connects the two halves of the brain. (pharmiweb.com)
  • Based on the information in the nerve impulses, the brain is able to identify the location and intensity of the pain and what kind of reaction it warrants. (wikipedia.org)
  • The lower seven cranial nerves and the major vessels to and from the brain traverse the temporal bone. (wikipedia.org)
  • changes
  • C fibers respond to all kinds of physiological changes in the body. (wikipedia.org)
  • The only signs are gradually progressive visual field loss, and optic nerve changes (increased cup-to-disc ratio on fundoscopic examination). (wikipedia.org)
  • or from skin, nerve and other changes caused by a hormone imbalance or immune response. (wikipedia.org)
  • muscle
  • The external urethral sphincter originates at the ischiopubic ramus and inserts into the intermeshing muscle fibers from the other side. (wikipedia.org)
  • The urethrovaginal muscle fibers wrap around the vagina and urethra and contraction leads to constriction of both the vagina and the urethra. (wikipedia.org)
  • giant
  • P f /P d ratios for lobster walking leg nerve fibers were found to be about 20 ± 7 at 14°C. P d measurements were made for squid giant axons at 25°C. and found to yield a value of 4 x 10 -4 cm. -1 sec. -1 . (rupress.org)
  • The medial giant interneuron (MG) is an interneuron in the abdominal nerve cord of crayfish. (wikipedia.org)
  • Giant nerve fiber system of the crayfish. (wikipedia.org)
  • signals
  • Within the brain, reception of a signal for a stressor by the hypothalamus leads to an increase in activity of the sympathoadrenal system, essentially within the nerves that send signals to the adrenal glands. (wikipedia.org)
  • researchers
  • Next, the researchers want to learn about the specific mechanisms that enable the micelles to restore function to damaged nerve cells. (orthospinenews.com)
  • University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials. (innovations-report.com)
  • Researchers including Alfredson and his team in Sweden believe these nerve fibers to be the cause of the pain - they injected local anaesthetic around the vessels and this decreased significantly the pain from the Achilles tendon. (wikipedia.org)
  • muscles
  • There have been theories that it is a type of Herpes virus that has somehow gotten into the nerve conductors that control muscles, these too are wishy washy so far with no real hard evidence as of yet. (aboutbfs.com)
  • Brain
  • Craniofacial resection can help preserve the optic nerves and brain while removing the cribriform plate, olfactory bulb, dura surrounding the bulb and even the orbital periosteum. (wikipedia.org)
  • activity
  • BenfoMax maintains healthy advanced glycation end (AGE) product activity which supports vascular, nerve, retinal and kidney health. (forresthealth.com)
  • Orthostatic syncope is caused by response failure or a lack of sympathetic nerve activity to the orthostatic challenge, followed by fluid shift and subsequent low cerebral perfusion. (frontiersin.org)
  • layers
  • Histological structure of the type 3 juncturae is denser and thicker than type 2 juncturae and tendinous fibers are arranged in two layers. (wikipedia.org)
  • System
  • Since both the sympathetic nerve fibers and adrenal medulla are part of the central nervous system (CNS), electrical impulses carried by the nervous system are converted to a chemical response in the adrenal gland. (wikipedia.org)
  • pressure
  • Known as Pregnancy-Related Sciatica, it is caused by the pressure of the baby on the sciatic nerve. (sciaticnervecure.info)
  • With brachial plexopathy, surgical decompression may be warranted if the pathophysiology of the disease is causing pressure on the affected nerves. (wikipedia.org)