• axon
  • Quantitative sudomotor axon reflex testing (QSART) measures sweating response at local body sites to evaluate the small nerve fibers that innervate sweat glands. (wikipedia.org)
  • cerebral
  • The total number of long range fibers within a cerebral hemisphere is 2% of the total number of cortico-cortical fibers (across cortical areas) and is roughly the same number as those that communicate between the two hemispheres in the brain's largest white tissue structure, the Corpus callosum. (wikipedia.org)
  • Aggregates of gray matter such as the basal ganglia (caudate nucleus, putamen, globus pallidus, substantia nigra, subthalamic nucleus, nucleus accumbens) and brainstem nuclei (red nucleus, cranial nerve nuclei) are spread within the cerebral white matter. (wikipedia.org)
  • humans
  • To investigate the role of small myelinated afferents in nonhistaminergic itch, we tested, in psychophysical studies in humans, the effect of a differential nerve block on itch produced by intradermal insertion of spicules from the pods of a cowhage plant ( Mucuna pruriens ). (jneurosci.org)
  • cranial
  • Malignant cells can migrate along spinal or cranial nerve epineurium-perineurium, invade the subpial space, and travel along blood vessels into the endoneurial space, or invade the nerve parenchyma. (wikipedia.org)
  • These cells have the ability to penetrate the pial membrane and invade the spinal cord and cranial nerves. (wikipedia.org)
  • Diplopia is the most common symptom of cranial nerve dysfunction. (wikipedia.org)
  • NM diffused infiltration of tumor cells into the subarachnoid space may be associated with increased intracranial pressure, signs of meningeal irritation, and damage to the cranial and spinal nerve roots. (wikipedia.org)
  • signals
  • CIPA is caused by a genetic mutation which prevents the formation of nerve cells which are responsible for transmitting signals of pain, heat, and cold to the brain. (wikipedia.org)
  • small
  • These fibers, categorized as C fibers and small Aδ fibers, are present in skin, peripheral nerves, and organs. (wikipedia.org)
  • Patients with Fabry disease have isolated small fiber engagement, and can have a more widespread small fiber disruption. (wikipedia.org)
  • There are many possible causes of small fiber neuropathy. (wikipedia.org)
  • A recent study revealed dysfunction of a particular sodium channel (Nav1.7) in a significant portion of the patient population with an idiopathic small fiber neuropathy. (wikipedia.org)
  • The diagnosis of small fiber neuropathy often requires ancillary testing. (wikipedia.org)
  • Specimens are sent to a specialized laboratory for processing and analysis where the small nerve fibers are quantified by a neuropathologist to obtain a diagnostic result. (wikipedia.org)
  • sensations
  • These findings demonstrate that activity in nociceptive, myelinated afferents contributes to cowhage-induced sensations, and that nonhistaminergic itch is mediated through activity in both unmyelinated and myelinated afferents. (jneurosci.org)
  • control
  • Fourteen subjects (7 female, 7 male) were each given two to four control tests with cowhage on the dorsum of the hand within the anticipated autonomous zone of the superficial branch of the radial nerve (in the region of the interosseus muscle and extending to the base of the thumb and adjacent two fingers). (jneurosci.org)
  • Rho, Rac, and Cdc42 have been the most extensively characterized family members and were originally implicated in the signal transduction pathways that control actomyosin assembly in stress fibers, lamellipodia, and filopodia, respectively. (jneurosci.org)
  • density
  • His most recent work on the specific and non-specific binding of tetrodotoxin has provided new information about the density of sodium channels in various types of nerve. (wikipedia.org)
  • This skin punch biopsy measurement technique is called intraepidermal nerve fiber density (IENFD). (wikipedia.org)
  • induces
  • The basic concept of the Marr-Albus theory is that the climbing fiber serves as a "teaching signal", which induces a long-lasting change in the strength of parallel fiber inputs. (wikipedia.org)
  • known
  • The most common cause of mononeuropathy is physical compression of the nerve, known as compression neuropathy. (wikipedia.org)
  • investigate
  • Electrophysiological experiments in anesthetized monkey were used to investigate the responsiveness of cutaneous, nociceptive, myelinated afferents to different chemical stimuli (cowhage spicules, histamine, capsaicin). (jneurosci.org)
  • type
  • More than one type of nerve may be affected at the same time. (wikipedia.org)
  • Observations of long-term depression in parallel fiber inputs have provided support for theories of this type, but their validity remains controversial. (wikipedia.org)
  • often
  • Polyneuropathy" is a pattern of nerve damage that is quite different from mononeuropathy, often more serious and affecting more areas of the body. (wikipedia.org)
  • role
  • However, rigorous psychophysical and neurophysiological evidence for a functional role of A-fibers in the mediation of nonhistaminergic itch in primates is lacking. (jneurosci.org)
  • pass
  • The endoneurium runs longitudinally along the nerve fiber, but with discontinuities where septa pass inward from the innermost layer of the perineurium. (wikipedia.org)