• axon
  • Dr Massimo Hilliard said that the discovery of gene mec-17 causing axon (nerve fibre) degeneration could open the door to better understand the mechanisms of neuronal injury and neurodegenerative diseases characterised by axonal pathology, such as motor neuron disease, Parkinson's, Alzheimer's and Huntington's diseases. (neurosciencenews.com)
  • With funding from the European Research Council and the Wellcome Trust, Holt's research group is aiming to better understand the molecular and cellular mechanisms that guide and maintain axon growth , which in turn will aid better understanding of how nerve connections are first established. (medicalxpress.com)
  • Schwann cell precursors (a first derivative of Neural crest cells) are present as the nerve axon grows from the dorsal neural tube, but it has been shown that these glial precursors are not essential to axonal growth. (wikipedia.org)
  • Bell's Palsy, which is thought to occur due to a viral reactivation which can lead (through unknown mechanisms) to diffuse axon demyelination and degeneration of the seventh cranial nerve, results in a hemifacial paralysis due to non-functionality of the nerve. (wikipedia.org)
  • neurons
  • This is particularly true for neurons, especially the extensions called axons that transmit electrochemical signals to other nerve cells. (medicalxpress.com)
  • Neural crest cells are found in the dorsal neural tube from which nerves and glia alike grow and Neural crest cells are the precursors to many various tissue types including enteric neurons and glia. (wikipedia.org)
  • Spinal muscular atrophies (SMAs) are a genetically and clinically heterogeneous group of rare debilitating disorders characterised by the degeneration of lower motor neurons (neuronal cells situated in the anterior horn of the spinal cord) and subsequent atrophy (wasting) of various muscle groups in the body. (wikipedia.org)
  • humans
  • These results indicate that the gene transfer of GDNF, BDNF, TGFβ2, and GIF and oral administration of T-588 may prevent the degeneration of motoneurons in adult humans with motoneuron injury and motor neuron diseases. (nii.ac.jp)
  • Brain
  • the cordlike association of nerve tissues that links the brain and nerve ganglia by innervation to the other organs and tissues of the body. (thefreedictionary.com)
  • The researchers hope to discover new pain drugs that take aim only at the peripheral nerve system, while not affecting the brain and the rest of the central nervous system. (neuropathyhomeremedy.com)
  • Scientists at the Queensland Brain Institute (QBI) have identified a gene that protects against spontaneous, adult-onset progressive nerve degeneration. (neurosciencenews.com)
  • The right facial nerves of adult Fischer 344 male rats were avulsed and adenoviral vectors encoding glial cell line-derived neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF), transforming growth factor-β2 (TGFβ2), and growth inhibitory factor (GIF) were injected into the facial canal. (nii.ac.jp)
  • Cambridge neuroscientists and mathematicians are using a variety of techniques to understand how the brain 'wires up', and what it might be able to tell us about degeneration in later life. (medicalxpress.com)
  • Über
  • Über eine dem Bilde der cerebrospinalen grauen Degeneration ähnliche Erkrankung des centralen Nervensystems ohne anatomischen Befund, nebst einigen Bemerkungen über paradoxe Contraction. (wikipedia.org)
  • Symptoms
  • Many cases of coenurosis probably existed years before it was recognized or discovered, but the first cases to be diagnosed were as follows: T. multiceps: Diagnosed for the first time in 1913 in Paris, when a man presented symptoms of CNS nerve degeneration. (wikipedia.org)
  • severe
  • After going through alot of tests they found I have severe muscle and nerve degenation in my lower back. (medhelp.org)
  • In the case that all is negative maybe you should consider surgery after everything in the case you are young since it can get solved but please make sure to check with few other doctors) Normally surgery happens when the nerve degeneration is so severe that is the only mechanism to try to regenerate the damaged nerve. (medhelp.org)
  • Hereditary neuralgic amyotrophy (HNA) is a neuralgic disorder that is characterized by nerve damage and muscle atrophy, preceded by severe pain. (wikipedia.org)
  • The severe pain of HNA can be controlled with an anti-inflammatory drug such as prednisone, although it is unknown whether these anti-inflammatory drugs actually slow or stop the nerve degeneration process. (wikipedia.org)
  • However, in a severe case permanent nerve damage may occur. (wikipedia.org)
  • sympathetic
  • The present study shows that all SCI individuals were able to maintain MAP by increasing leg vascular resistance during head-up tilt, despite nerve degeneration in L and lack of centrally mediated sympathetic control in all SCI individuals. (ru.nl)
  • rats
  • The team, led by Jeffrey Isner of Tufts University School of Medicine in Boston, Massachusetts, injected the VEGF-1 and VEGF-2 genes into the leg muscles of diabetic rats and rabbits to stimulate blood vessel growth around degenerating nerves. (genomenewsnetwork.org)
  • reflexes
  • It was in this paper that Dr. Spiegel suggested that pre-examination of the patients' range of motion and reflexes would eliminate time and exploration of nerve entrapments during the electromyoneurographic procedure. (wikipedia.org)
  • patients
  • A study conducted on patients with proximal radial nerve injuries used the procedure to indicate the degree of both pre- and postoperative nerve damage. (wikipedia.org)
  • When looking at the sample data table, one can see that postoperative patients generally see an increase in mean radial nerve amplitude, a decrease in mean radial nerve latency and increases in nerve motor conduction velocity. (wikipedia.org)
  • researchers
  • This technology will allow researchers to test potential drugs for treating pain using the nerve cells in a lab, all based on an individual patient's own genetic signature, says Mick Bhatia, who led the team of researchers at McMaster University in Hamilton. (neuropathyhomeremedy.com)
  • Blood turned into nerve cells by Canadian researchers. (neuropathyhomeremedy.com)
  • muscle
  • The scientists studied the molecular processes involved in these changes and discovered that the activation of the Ret receptor counteracts the muscle degeneration. (healthcanal.com)
  • Perisynaptic Schwann Cells (PSCs) contribute to the tripartite synapse organization in combination with the pre-synaptic nerve and the post-synaptic muscle fiber. (wikipedia.org)
  • Various forms of physiotherapy and occupational therapy are frequently able to slow down the pace of nerve degeneration and muscle wasting. (wikipedia.org)
  • Electromyoneurography is a technique that uses surface electrical probes to obtain electrophysiological readings from nerve and muscle cells. (wikipedia.org)
  • This procedure now analyzes the nerve conduction and muscle potentials through the use of H-Reflex and F-Wave studies. (wikipedia.org)
  • Electromyoneurography's unique combination of recording in muscle and nerve simultaneously typically results in a higher level of diagnostic ability in the field of medicine. (wikipedia.org)
  • diseases
  • I have degeneration disk diseases is there any I can do for pain out surgery. (medhelp.org)
  • Mutant forms of the protein associated with peripheral nerve disease have been shown to aberrantly bind to the transmembrane receptor proteins neuropilin 1 and Trk receptors A-C. Glycyl-tRNA synthetase has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. (wikipedia.org)
  • The peripheral nerve diseases Charcot-Marie-Tooth disease type 2D (CMT2D) and distal spinal muscular atrophy type V (dSMA-V) have been liked to dominant mutations in GARS. (wikipedia.org)
  • neural
  • These neural stem cells are then manipulated in the lab to give rise to several types of nerve cells, including those that make up the peripheral nervous system throughout the arms, legs and the rest of the body. (neuropathyhomeremedy.com)
  • It was found that these newly discovered cells were present in nerve degeneration models, showing their non-neural nature. (wikipedia.org)
  • motor
  • He extensively used electrodiagnostic testing and demonstrated heightened motor nerve sensitivity in tetanus. (wikipedia.org)
  • damage
  • See your Chicago chiropractor for relief of nerve compression and for prevention of damage to the nerve being compressed. (coxchirocare.com)
  • The high level of sensitivity that electromyoneurography employs makes it ideal for detecting peripheral nerve damage as well as a variety of myopathies in their early stages. (wikipedia.org)
  • cells
  • Canadian scientists have discovered a way to turn a simple blood sample from a man or woman into a variety of nerve cells, including those that are responsible for pain, numbness and other sensations. (neuropathyhomeremedy.com)
  • results
  • These results are all general trends that would be expected when operating on damaged nerves in effort to increase their performance. (wikipedia.org)
  • Function
  • If the recurrent larangyl nerve is targeted, the pharynx will begin to atrophy and voice function may be lost. (wikipedia.org)