• fetal
  • We describe a kindred in which the index case presented with fetal hydrops, and early neonatal death, and the second child had severe anaemia at delivery. (bmj.com)
  • This observation was experimentally validated by Rupert E. Billingham and Peter Medawar in 1953, who showed by injecting foreign cells into fetal or neonatal mice, they could become accepting of future grafts from the same foreign donor. (wikipedia.org)
  • mucosal
  • When the GALT receives signals from the intestinal flora or food Ags, it must induce a state of nonresponsiveness (mucosal tolerance). (jimmunol.org)
  • Quantitative morphologic differences in the rectal mucosa biopsies were noted with EGF(1-48) treatment compared with baseline or placebo and included a statistically significant increase in the number of mitoses per mucosal crypt on study day 4, significantly increased thickness of rectal mucosa from baseline on study days 4 and 7, and increased crypt surface area of rectal mucosa in parallel with increased mucosa thickness on day 14. (ox.ac.uk)
  • The relevant evidence for the role of EGF in intestinal development and mucosal repair, as well as its potential involvement in the genesis of NEC will be reviewed. (biomedsearch.com)
  • Organoid units are multicellular aggregates derived from the intestine that contain both mucosal and mesenchymal elements, 3 the relationship between which preserves the intestinal stem cell niche. (jove.com)
  • At birth, the neonate's mucosal immune system is relatively undeveloped, but the colonization of intestinal flora promotes its development. (wikipedia.org)
  • absorptive
  • Fasting between 0 and 48 hours post hatch decreased crypt size, the number of crypts per villus, crypt proliferation, villus area, and the rate of enterocyte (intestinal absorptive cells) migration in the duodenum and jejunum. (wikipedia.org)
  • malabsorption
  • In young children and previously unexposed adults, particularly travelers from low- to high-prevalence parts of the world, Giardia can produce serious diarrhoeal illness with intestinal malabsorption, marked weight loss, and in infants and young children, impairment of growth and development. (lww.com)
  • Excessive alcohol consumption Excessive consumption of antidiuretics or inadequate levels of antidiuretic hormone Intestinal malabsorption caused by short bowel syndrome Ketogenic Diet Biotin is a coenzyme for five carboxylases in the human body (propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, pyruvate carboxylase, and 2 forms of acetyl-CoA carboxylase. (wikipedia.org)
  • pigs
  • The aim of the study was to investigate the effect of exogenous ghrelin, administered intra-gastrically, on the processes of mitosis, apoptosis, autophagy, crypt fission and changes in histometry of the small intestine mucosa in neonatal pigs, fed with a milk formula. (lu.se)
  • milk
  • Compared to the control group (C7), feeding milk formula supplemented with ghrelin resulted in significant changes in the small intestinal morphometry and mucosa histometry. (lu.se)
  • Moreover, direct actions on tissues other than the gut mucosa would further require that substantial amounts of milk growth factors are absorbed intact into the neonatal circulation. (springer.com)
  • Humans
  • 5 The availability of immunocompromised mouse strains will also permit us to apply the technique to human intestinal tissue and optimize the formation of human TESI as a mouse xenograft before its transition into humans. (jove.com)
  • small
  • Moreover, we demonstrated that autophagy is involved in the small intestine mucosa remodeling and ghrelin may be an important factor for its regulation. (lu.se)
  • Meconium ileus accounts for up to 33% of neonatal small-bowel obstructions. (merckmanuals.com)
  • It originates from telangiectatic small blood vessels in the intestinal mucosa. (wikipedia.org)
  • Biotin deficiency rarely occurs among healthy people because the daily requirement of biotin is low, many foods provide adequate amounts of it, intestinal bacteria synthesize small amounts of it, and the body effectively scavenges and recycles it from bodily waste. (wikipedia.org)
  • Disease
  • Despite the frequency of these procedures, a significant knowledge gap remains in describing the inherent effects of intestinal resection on host physiology and disease pathophysiology. (jove.com)
  • Once mastered, the murine ileocolic resection procedure will provide a reproducible tool for studying the effects of intestinal resection in models of human disease. (jove.com)
  • blood
  • If a child is not diagnosed during the routine newborn screening test (typically performed 2-7 days after birth, using samples drawn by neonatal heel prick), and a phenylalanine restricted diet is not introduced, then phenylalanine levels in the blood will increase over time. (wikipedia.org)