Negative allosteric modulator allosteric site. Medical search. Frequent questions

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Anatomy4

HEK293 Cells CHO Cells Cell Line Oocytes

Organisms6

Erythrocebus patas Cricetinae Cricetulus Rats, Sprague-Dawley Xenopus laevis Escherichia coli

Chemicals and Drugs82

Receptor, Metabotropic Glutamate 5 Cyclohexylamines Receptors, Metabotropic Glutamate Receptors, Calcium-Sensing Receptors, Nicotinic Pyridines Benzamides Phthalimides N-Methylscopolamine Gallamine Triethiodide Calcium Obidoxime Chloride Receptor, Muscarinic M2 Receptors, GABA-A Alcuronium Receptor, Muscarinic M1 GABA Modulators Ligands Isoindoles Phosphofructokinases Receptor, Muscarinic M4 alpha7 Nicotinic Acetylcholine Receptor Tacrine Isoxazoles MSH Release-Inhibiting Hormone Adenosine Monophosphate Cholinergic Agents Fructosediphosphates GABA-A Receptor Agonists Fructose-Bisphosphatase Glycogen Phosphorylase, Muscle Form Benzothiadiazines Muscarinic Agonists Receptors, Muscarinic Benzodiazepines Pregnanolone Piperidines Nootropic Agents Carbolines Phenylurea Compounds Bicyclo Compounds Receptors, G-Protein-Coupled Nicotinic Agonists Adenosine Triphosphate Nicotinic Acids GABA-B Receptor Agonists Diazepam Small Molecule Libraries Excitatory Amino Acid Agents Nicotinic Antagonists Ribonucleotide Reductases Galantamine Thiophenes Receptor, Muscarinic M5 Hexosediphosphates Recombinant Proteins Cyclic Nucleotide Phosphodiesterases, Type 5 Cytidine Diphosphate GABA Agents Receptors, GABA-B Protein Subunits Adenosine Diphosphate Hydrocarbons, Brominated Glucose-6-Phosphate Excitatory Amino Acid Agonists Glutamic Acid Pentobarbital GABA Agonists Receptors, AMPA Affinity Labels Thiadiazoles Receptor, Adenosine A1 3',5'-Cyclic-GMP Phosphodiesterases Aspartate Carbamoyltransferase Central Nervous System Agents Amides Pregnanediones Aniline Compounds Acetylcholine Peptidomimetics Xanthenes Nucleotides

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Radioligand Assay Models, Molecular Binding, Competitive Drug Discovery Crystallography, X-Ray Mutagenesis, Site-Directed Drug Design Models, Chemical Amino Acid Substitution Models, Biological Molecular Dynamics Simulation Patch-Clamp Techniques High-Throughput Screening Assays

Phenomena and Processes24

Allosteric Regulation Allosteric Site Structure-Activity Relationship Dose-Response Relationship, Drug Binding Sites Protein Binding Kinetics Binding, Competitive Protein Conformation Molecular Structure Protein Structure, Tertiary Catalytic Domain Amino Acid Sequence Protein Structure, Quaternary Mutation Protein Structure, Secondary Amino Acid Substitution Dimerization Drug Partial Agonism Enzyme Activation Drug Interactions Signal Transduction Molecular Dynamics Simulation Substrate Specificity

Disciplines and Occupations2

Drug Discovery Drug Design

Information Science3

Amino Acid Sequence Molecular Sequence Data Molecular Dynamics Simulation

Anatomy Organisms Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Allosteric Regulation Allosteric Site Receptor, Metabotropic Glutamate 5 Cyclohexylamines Receptors, Metabotropic Glutamate Erythrocebus patas Receptors, Calcium-Sensing Receptors, Nicotinic Structure-Activity Relationship Pyridines Benzamides Phthalimides Dose-Response Relationship, Drug N-Methylscopolamine Radioligand Assay Gallamine Triethiodide Calcium Binding Sites Models, Molecular Obidoxime Chloride Protein Binding Receptor, Muscarinic M2 Receptors, GABA-A Alcuronium Cricetinae Receptor, Muscarinic M1 GABA Modulators Kinetics HEK293 Cells Ligands Binding, Competitive Isoindoles Phosphofructokinases Receptor, Muscarinic M4 alpha7 Nicotinic Acetylcholine Receptor Protein Conformation CHO Cells Cell Line Cricetulus Molecular Structure Tacrine Rats, Sprague-Dawley Protein Structure, Tertiary Isoxazoles Drug Discovery Crystallography, X-Ray MSH Release-Inhibiting Hormone Adenosine Monophosphate Catalytic Domain Cholinergic Agents Fructosediphosphates GABA-A Receptor Agonists Fructose-Bisphosphatase Glycogen Phosphorylase, Muscle Form Mutagenesis, Site-Directed Benzothiadiazines Muscarinic Agonists Amino Acid Sequence Receptors, Muscarinic Benzodiazepines Drug Design Molecular Sequence Data Pregnanolone Piperidines Nootropic Agents Protein Structure, Quaternary Carbolines Phenylurea Compounds Bicyclo Compounds Receptors, G-Protein-Coupled Xenopus laevis Mutation Nicotinic Agonists Adenosine Triphosphate Nicotinic Acids Models, Chemical GABA-B Receptor Agonists Diazepam Small Molecule Libraries Protein Structure, Secondary Excitatory Amino Acid Agents Nicotinic Antagonists Ribonucleotide Reductases Galantamine Thiophenes Receptor, Muscarinic M5 Hexosediphosphates Escherichia coli Recombinant Proteins Amino Acid Substitution Cyclic Nucleotide Phosphodiesterases, Type 5 Cytidine Diphosphate GABA Agents Receptors, GABA-B Models, Biological Dimerization Protein Subunits Adenosine Diphosphate Hydrocarbons, Brominated Glucose-6-Phosphate

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