Other alkaloids possess psychotropic (e.g. psilocin) and stimulant activities (e.g. cocaine, caffeine, nicotine, theobromine), and have been used in entheogenic rituals or as recreational drugs. (wikipedia.org)
(Brown, 2017) Psilocin is regarded as a prototypic classical psychedelic, and thus the main psychoactive effects of psilocin are due to binding to the 5-HT2A and 5-HT2C serotonin receptor subtypes, where it acts with high specificity as a partial agonist. (researchgate.net)
Psychedelic1
The lysergamides include LSD and lysergic acid hydroxyethylamide, which is a naturally occurring psychedelic found in morning glory seeds. (medscape.com)
Perception1
The stimulation of the 5-HT2A receptor is understood to be predominantly responsible for the characteristic psychoactive effects of 'changes in perception, visual patterns and discrete images, euphoria, distorted sense of time, synesthesia, emotional lability, and sometimes mystical or spiritual experiences' (Brown, et al. (researchgate.net)
Similar2
Some synthetic compounds of similar structure may also be termed alkaloids. (wikipedia.org)
Less similar and more toxic is A. pantherina, the Panther Cap. (sacredearth.com)
Group1
This group also includes some related compounds with neutral and even weakly acidic properties. (wikipedia.org)
Hydrogen1
In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen or sulfur. (wikipedia.org)
Substances4
The present study aims to develop a forensic toxicological library to identify 56 natural toxic substances by liquid chromatography-quadrupole time-of-flight tandem mass spectrometry (LC-QTOF-MS/MS). (springermedizin.de)
This library will be more effective for the screening of natural toxic substances in routine forensic toxicological analysis. (springermedizin.de)
To our knowledge, there are no reports dealing with development of library for natural toxic substances by LC-QTOF-MS/MS. (springermedizin.de)
In other words, when it comes to mixing psychoactive substances, the sum is more often than not different from the sum of its parts. (qualiacomputing.com)
Humans2
Although alkaloids act on a diversity of metabolic systems in humans and other animals, they almost uniformly evoke a bitter taste. (wikipedia.org)
Alkaloid-containing plants have been used by humans since ancient times for therapeutic and recreational purposes. (wikipedia.org)
Organisms1
Alkaloids are produced by a large variety of organisms including bacteria, fungi, plants, and animals. (wikipedia.org)
Serotonin2
Natural compounds containing nitrogen in the exocyclic position (mescaline, serotonin, dopamine, etc.) are usually classified as amines rather than as alkaloids. (wikipedia.org)
For example, while 5-MeO-DMT is relatively safe when vaporized (save for egregiously negligent uses of the drug and the occasional drowning in one's own vomit), taking 5-MeO-DMT orally in combination with an MAOI leads to extremely toxic reactions, such as severe hypertensive symptoms, overheating, and serotonin syndrome . (qualiacomputing.com)
Drug1
Consequently, fly-agaric (whether it is thought-about in any respect) is regarded solely as a harmful and probably toxic 'drug', fairly than a path to the divine. (rmt-racing.com)
Natural1
The boundary between alkaloids and other nitrogen-containing natural compounds is not clear-cut. (wikipedia.org)
Plants1
Extracts from plants containing toxic alkaloids, such as aconitine and tubocurarine, were used since antiquity for poisoning arrows. (wikipedia.org)
Development2
A significant contribution to the chemistry of alkaloids in the early years of its development was made by the French researchers Pierre Joseph Pelletier and Joseph Bienaimé Caventou, who discovered quinine (1820) and strychnine (1818). (wikipedia.org)
The development of the chemistry of alkaloids was accelerated by the emergence of spectroscopic and chromatographic methods in the 20th century, so that by 2008 more than 12,000 alkaloids had been identified. (wikipedia.org)