• prognostic
  • In severe sepsis patients, however, no information is available yet about the prognostic value of natriuretic peptides. (ahajournals.org)
  • In the present study, we investigated the potential of N-BNP (N-terminal B-type natriuretic peptide) as a prognostic marker for risk of CV (cardiovascular) events, overall mortality and progression to ESRD (end-stage renal disease) in a cohort of 83 pre-dialysis CKD (chronic kidney disease) patients without clinical evidence of heart failure. (clinsci.org)
  • dysfunction
  • Background- Increased plasma levels of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) have been identified as predictors of cardiac dysfunction and prognosis in congestive heart failure and ischemic heart disease. (ahajournals.org)
  • 7 8 9 10 11 The relationship between these natriuretic peptides and survival is believed to be based mainly on their reflection of increased LV filling pressure secondary to LV dysfunction. (ahajournals.org)
  • In this report, we present data from a cohort of 131 patients with documented AMI and a median follow-up time of 1293 days, and we compare the merit of these three members of the cardiac natriuretic peptide family as indicators of LV dysfunction, defined as LV ejection fraction ≤45%, and long-term survival after AMI. (ahajournals.org)
  • kidney
  • Lower levels of NPPA expression are found in other tissues such as the brain, kidney, lung, uterus and placenta. (wikipedia.org)
  • mortality
  • McQuade and colleagues ( 1 ) suggest that achieving predischarge natriuretic peptide (NP) thresholds is associated with reduced heart failure mortality and readmissions. (annals.org)
  • antibody
  • The antibody was raised in rabbit using a synthetic peptide, and can be used for immunohistochemical (IHC) detection of human BNP. (clontech.com)
  • myocardial
  • 4 The likelihood ratio for a patient without a history of myocardial infarction, with negative results on chest radiography and electrocardiography, and with concentrations of brain natriuretic peptide below the cut off, individually and in combination, are shown in the table. (bmj.com)
  • decrease
  • The net effect of these peptides is a decrease in blood pressure due to the decrease in systemic vascular resistance and, thus, afterload. (wikipedia.org)
  • biological
  • The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing. (wikipedia.org)
  • Cleavage at other sites produces shorter BNP peptides with unknown biological activity. (wikipedia.org)
  • blood
  • Brain lymphoma, sometimes called primary lymphoma of the brain, is cancer of an individual's white blood cells that starts in the brain, states MedlinePlus. (reference.com)