• Nafarelin, sold under the brand name Synarel among others, is a gonadotropin-releasing hormone agonist (GnRH agonist) medication which is used in the treatment of endometriosis and early puberty. (wikipedia.org)
  • A bottle of nafarelin nasal spray (brand name Synarel) lasts for about 7 days at a dosage of 1,600 μg/day. (wikipedia.org)
  • Each bottle of nafarelin nasal spray (brand name Synarel) contains about 60 sprays delivering approximately 200 μg nafarelin in 100 μL solution per actuation. (wikipedia.org)
  • Normal supplies of Synarel ® Nasal Spray are expected to resume in mid-May 2023. (hps.com.au)
  • Nafarelin , sold under the brand name Synarel among others, is a medication used to treat endometriosis and early puberty . (mdwiki.org)
  • The recipient will need to take Nafarelin (Synarel) nasal spray daily, from day 2 or 21 of the menstrual cycle, until the day before the donors egg collection. (cyprusivf.ru)
  • GnRH agonists products include Lupron Depot-Ped (leuprolide acetate), Fensolvi (leuprolide acetate), Synarel (nafarelin), Supprelin LA (histrelin), and Triptodur (triptorelin)," one report explains. (medicalviolence.com)
  • The medication is used as a nasal spray two to three times per day. (wikipedia.org)
  • Nafarelin is available in the form of a 0.2% nasal spray for use one, two, or three times per day. (wikipedia.org)
  • [9] It is one of two GnRH analogues available as a nasal spray, the other being buserelin . (mdwiki.org)
  • The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being buserelin. (wikipedia.org)
  • Nafarelin is a GnRH agonist, or an agonist of the GnRH receptor, the biological target of GnRH. (wikipedia.org)
  • As a result, nafarelin suppresses the GnRH-induced secretion of the gonadotropins, luteinizing hormone and follicle-stimulating hormone, from the pituitary gland. (wikipedia.org)
  • Nafarelin is a GnRH analogue, or a synthetic analogue of GnRH. (wikipedia.org)
  • Monroe SE, Blumenfeld Z, Andreyko JL, Schriock E, Henzl MR, Jaffe RB: Dose-Dependent Inhibition of Pituitary-Ovarian Function during Administration of a GnRH Agonistic Analog (Nafarelin). (sapub.org)
  • There is a case report of severe hyperkalemia during nafarelin therapy in a woman with uterine fibroids. (wikipedia.org)
  • Nafarelin was introduced for medical use in 1990. (wikipedia.org)
  • Nafarelin can also be used to treat hirsutism and polycystic ovary syndrome by lowering gonadotropin and androgen levels. (wikipedia.org)
  • Nafarelin is used to treat precocious puberty at a dosage of 1,600 to 1,800 μg per day. (wikipedia.org)
  • Nafarelin is used to treat endometriosis at lower dosages of 400 to 800 μg per day. (wikipedia.org)
  • The elimination half-life of nafarelin is 2.5 to 3.0 hours by intranasal administration, whereas the half-life of nafarelin and its metabolites by subcutaneous injection is 85.5 hours. (wikipedia.org)
  • Nafarelin, sold under the brand name Synarel among others, is a gonadotropin-releasing hormone agonist (GnRH agonist) medication which is used in the treatment of endometriosis and early puberty. (wikipedia.org)
  • Nafarelin acetate, sold under the brand name Synarel, and buserelin, sold under the brand name Suprecur, are GnRH agonists taken via a daily nasal spray. (devonzuegel.com)
  • Agonists with two substitutions include leuprorelin, buserelin, histrelin, goserelin, and deslorelin: the agent's nafarelin and triptorelin are agonists with single substitutions at position (vi). (phcoker.com)
  • Drugs including leuprolide, nafarelin and goserelin, which are all approved by the Food and Drug Administration, put the brakes on these ovary-stimulating hormones. (getmegiddy.com)
  • The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being buserelin. (wikipedia.org)
  • GnRH agonists are given by injections into fat, as implants placed into fat, and as nasal sprays. (phcoker.com)
  • Commonly prescribed for six months to a year, these drugs may take the form of tablets, injections or injectable implants, and nasal sprays. (getmegiddy.com)
  • 8. Ovulation inhibition with nafarelin acetate nasal administration for six months. (nih.gov)
  • Nafarelin is used to treat endometriosis at lower dosages of 400 to 800 μg per day. (wikipedia.org)
  • Nafarelin is used to treat precocious puberty at a dosage of 1,600 to 1,800 μg per day. (wikipedia.org)
  • The elimination half-life of nafarelin is 2.5 to 3.0 hours by intranasal administration, whereas the half-life of nafarelin and its metabolites by subcutaneous injection is 85.5 hours. (wikipedia.org)
  • Close one nostril by gently placing your finger against the side of your nose, tilt your head slightly forward and, keeping the bottle upright, insert the nasal tip into the other nostril. (medlineplus.gov)
  • The authors of one of these new studies pointed out that eczema is common in infants but can lead to asthma and food and nasal allergies . (rxwiki.com)
  • Side effects of nafarelin are related to sex hormone deprivation and include symptoms of low testosterone levels and low estrogen levels such as hot flashes, sexual dysfunction, vaginal atrophy, and osteoporosis. (wikipedia.org)
  • Side effects of nafarelin are related to sex hormone deficiency and include hot flashes, vaginal dryness, headaches, mood changes, and sexual dysfunction. (wikipedia.org)
  • Nafarelin should be started between the second and fourth days of your menstrual period. (medlineplus.gov)