MyelomaTumorsBenignBrain neoplasmsMyeloproliferative NeoplasmsMelanomaMetastasisCarcinomaLymphoidMalignant neoplasmGrowths of tissueDiagnosisLymphomaEtiologyCancerLymphatic systemPancreasIntracranialSecondaryChronicMalignanciesOvarianMolecularArisesHistologyDiseaseFactorsHypertensionMESHMalignancyMetastaticGenesRectumColonCranial
Myeloma11
- 2) Plasmablastic plasma cell lymphoma or plasmablastic plasmacytoma: A lymphoid neoplasm that disseminates widely like the plasma cell lesions in multiple myeloma or is localized like the plasma cell lesions in plasmacytoma. (wikipedia.org)
- Multiple myeloma (MM) , also known as plasma cell myeloma , is a multifocal proliferation of plasma cells based in the bone marrow . (radiopaedia.org)
- Multiple myeloma remains incurable. (radiopaedia.org)
- Multiple myeloma accounts for one of the 'M's in the popular mnemonic for lucent bone lesions FEGNOMASHIC . (radiopaedia.org)
- As per the WHO classification of tumors of hematopoietic and lymphoid tissues , multiple myeloma is called plasma cell myeloma 14 . (radiopaedia.org)
- Smoldering multiple myeloma refers to a form that falls on the spectrum between monoclonal gammopathy of unknown significance (MGUS) and active multiple myeloma. (radiopaedia.org)
- Patients are asymptomatic, with worse biochemistry than MGUS but without the end-organ damage of active multiple myeloma 9 . (radiopaedia.org)
- Multiple myeloma and osteosarcoma combined account for ~50% of all primary bone malignancies 7 . (radiopaedia.org)
- 1 B cell neoplasms other than multiple myeloma including non-Hodgkin's lymphomas, and acute and chronic leukaemias might also exhibit lytic bone lesions, hypercalcaemia, and monoclonal gammopathy via the particular actions of interleukin (IL-1), IL-6, or tumour necrosis factor-α secreted by the neoplastic B cell clone, but not reported previously secondary to a primary cerebral lymphoma. (bmj.com)
- 5. Which of the following is a characteristic feature of multiple myeloma? (medicalbiochemist.com)
- Multiple Myeloma Multiple myeloma is a cancer of plasma cells that produce monoclonal immunoglobulin and invade and destroy adjacent bone tissue. (msdmanuals.com)
Tumors17
- Choroid plexus neoplasms are rare, intraventricular, primary central nervous system (CNS) tumors derived from choroid plexus epithelium that are seen predominantly in children. (medscape.com)
- [ 2 , 3 ] In adults, they account for less than 1% of primary intracranial neoplasms, whereas choroid plexus tumors represent up to 5% of pediatric brain tumors, and up to 20% of those arising in children aged 1 year and younger. (medscape.com)
- 3. Torre D. Multiple sebaceous tumors. (meduniver.com)
- Incidence of primary large bowel lymphomas comprises only 0.2-0.6% of large bowel malignant tumors ( 3 ). (frontiersin.org)
- The frequency of meningiomas in Africa is nearly 30% of all primary intracranial tumors. (medscape.com)
- Most primary brain tumors are solitary, but multiple primary brain tumors have been reported. (vin.com)
- Secondary or metastatic tumors appear to be less common and may result from local extension (e.g., nasal adenocarcinoma) or metastases from primary tumors elsewhere. (vin.com)
- Primary tumors other than meningiomas appear to be less common in cats than in dogs. (vin.com)
- Primary brain tumors originate from cells normally found within the brain and meninges. (vin.com)
- Secondary tumors are metastasis from a primary tumor located outside the nervous system, or occur by local invasion from adjacent non- neural tissues (e.g., bone). (vin.com)
- Pituitary gland neoplasms and tumors arising from cranial nerves are considered secondary brain tumors. (vin.com)
- Primary brain tumors often are slow growing and the brain adapts to the slow increase in ICP. (vin.com)
- Biochemical signs and severity of symptoms of primary hyperparathyroidism (pHPT) differ among patients, and little is known of any coupling of clinical characteristics of nonfamilial pHPT to genetic abnormalities in the parathyroid tumors. (lu.se)
- Hemangiosarcomas are locally invasive and multicentric ( having two or more primary tumors ). (ivis.org)
- The focused ultrasound assessment with sonograms in trauma (FAST) revealed multiple tumors in the heart which were then confirmed in echocardiographic examination performed by a veterinary cardiologist. (biomedcentral.com)
- Heart tumors (HT) are uncommon in companion animals, accounting for roughly 0.2% of all neoplasms. (biomedcentral.com)
- For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. (icd10data.com)
Benign1
- Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
Brain neoplasms1
- Gliomas are the most common primary brain neoplasms. (medscimonit.com)
Myeloproliferative Neoplasms2
- Patients with underlying hypercoagulable states, most frequently myeloproliferative neoplasms, are at highest risk for primary Budd-Chiari syndrome, and multiple genes have been associated. (logicalimages.com)
- 10. Which of the following is a common finding in myeloproliferative neoplasms (MPNs)? (medicalbiochemist.com)
Melanoma3
- Multiple malignant melanocytic lesions developed in a 54-year-old man 4 years after a primary malignant melanoma (Clark level IV) had been excised and 2 months after taking L-Dopa for Parkinsonism. (nih.gov)
- Choroidal melanoma is the most common primary malignant ocular tumor in human adults. (molvis.org)
- We have studied the transgenic mouse strain, Tyrp-1-TAg, to try to gain insight into possible molecular mechanisms common to pigmented ocular neoplasms occurring spontaneously in the eyes of these mice and human choroidal melanoma. (molvis.org)
Metastasis1
- Lee V, Gessler D, Cataltepe O. Case report: cranial angiosarcoma with multiple hemorrhagic brain metastasis in a child. (umassmed.edu)
Carcinoma2
- Transarterial radioembolization (TARE) with yttrium 90 is increasingly utilized for the treatment of hepatic neoplasms, whether primary (particularly hepatocellular carcinoma [HCC]) or metastatic (particularly colorectal). (thieme-connect.com)
- They also show that families with the CDKN2A 113insArg mutation have an increased risk not only of multiple melanomas and pancreatic carcinoma but also of breast cancer. (lu.se)
Lymphoid6
- Lymphoid neoplasms with plasmablastic differentiation were classified by the World Health Organization, 2017 as a sub-grouping of several distinct but rare lymphomas in which the malignant cells are B-cell lymphocytes that have become plasmablasts, i.e. immature plasma cells. (wikipedia.org)
- Due to their malignant nature, however, the plasmablasts in lymphoid neoplasms with plasmablastic differentiation do not mature into plasma cells or form antibodies but rather uncontrollably proliferate in and damage various tissues and organs. (wikipedia.org)
- The lymphoid neoplasms with plasmacytic differentiation are: 1) Plasmablastic lymphoma: The most common of these lymphoid neoplasms. (wikipedia.org)
- 6) Human herpesvirus 8-positive diffuse large B-cell lymphoma, not otherwise specified: This lymphoid neoplasm usually arises from the lymphoproliferative disease, idiopathic multicentric Castleman disease. (wikipedia.org)
- Except for human herpesvirus 8-positive diffuse large B-cell lymphoma, not otherwise specified, these lymphoid neoplasms are often associated with Epstein-Barr virus infection of the malignant plasmablastic cells. (wikipedia.org)
- In cases so infected, the lymphoid neoplasm may result, at least in part, from this viral infection and therefore can be considered as examples of the Epstein-Barr virus-associated lymphoproliferative diseases. (wikipedia.org)
Malignant neoplasm1
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. (icd10data.com)
Growths of tissue1
- Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
Diagnosis7
- Early diagnosis of primary intestinal NK/T cell lymphoma is frequently difficult. (frontiersin.org)
- Herein we report a case with unilateral abducens nerve palsy as initial symptom in the primary sphenoidal sinus ENKL and investigated the clinical feature of the diagnosis and therapy. (hindawi.com)
- Staging procedures including CT of the abdomen and pelvis, bilateral bone marrow aspiration, and biopsies were within normal limits precluding the diagnosis of primary cerebral lymphoma. (bmj.com)
- 2007) The utility of Pax-5 immunohistochemistry in the diagnosis of undifferentiated malignant neoplasms Mod. (roche.com)
- BACKGROUND: Spinal metastases are being diagnosed more frequently because of increasing life expectancies and advances in the diagnosis and therapy of primary tumours. (iospress.com)
- The occurrence of this tumor in the heart has been described only in a few publications in dogs, and such a multiple heart RMS as presented below is an extremely uncommon diagnosis not only in veterinary but also in human medicine. (biomedcentral.com)
- If the features of anxiety that are seen are not typical for a primary anxiety disorder, and there is a medical condition present, this is an indication that anxiety due to another medical condition may be an appropriate diagnosis. (theravive.com)
Lymphoma4
- Extranodal NK/T cell lymphoma is a rare non-Hodgkin lymphoma mainly involving the upper aerodigestive tract, even rarer is primary extranasal disease involving the intestine. (frontiersin.org)
- We present a case of primary intestinal NK/T cell lymphoma with diagnostic challenge, which eventually developed into multiple intestinal perforations. (frontiersin.org)
- Primary cerebral lymphoma is a unique and infrequent CNS malignancy in which the B lymphocyte subtype constitutes most cases. (bmj.com)
- 2 We describe an unusual presentation of a B cell primary cerebral lymphoma mimicking a plasma cell dyscrasia. (bmj.com)
Etiology1
- Clinicians should be careful to exclude other etiologies of liver failure that can predispose patients to developing hepatic venous outflow tract obstruction that is either nonocclusive or not the primary etiology of the patient's liver failure. (logicalimages.com)
Cancer2
- 0001). Families with breast cancer also had a propensity for multiple melanomas in females, suggesting that a sex-dependent factor may modify the phenotypic expression of CDKN2A alterations. (lu.se)
- Title : The effect of multiple primary rules on population-based cancer survival Personal Author(s) : Weir, Hannah K.;Johnson, Christopher J.;Thompson, Trevor D. (cdc.gov)
Lymphatic system1
- Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
Pancreas1
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified ( C25.9 ). (icd10data.com)
Intracranial2
- Choroid plexus neoplasms can produce hydrocephalus and increased intracranial pressure by a number of mechanisms, including obstruction of normal cerebrospinal fluid (CSF) flow, overproduction of CSF by the tumor itself, local expansion of the ventricles, or spontaneous hemorrhage. (medscape.com)
- Meningiomas account for approximately 20% of all primary intracranial neoplasms. (medscape.com)
Secondary5
- Radioembolization with 90 yttrium microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies. (thieme-connect.com)
- Synovial chondromatosis occurs as either a primary or a secondary form. (medscape.com)
- Budd-Chiari syndrome is hepatic venous outflow tract obstruction due to either primary vascular occlusion (thrombosis) or secondary occlusion from extrinsic compression (eg, malignancy). (logicalimages.com)
- Examination of cells whether from a primary or secondary site, including fluids aspirated using endoscopes or needles. (who.int)
- It can be present in two forms: primary or secondary. (bvsalud.org)
Chronic2
- Common types of MPNs include chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). (medicalbiochemist.com)
- 1. Which of the following is NOT a primary characteristic feature of chronic myeloid leukemia (CML)? (medicalbiochemist.com)
Malignancies2
- It accounts for 1% of all malignancies and 10-15% of all hematological neoplasms 12,14 . (radiopaedia.org)
- Two cases of multiple primary malignancies (two or more neoplasms without any relationship between them) are presented in this paper. (banglajol.info)
Ovarian1
- 18 With the exception of the ovarian neoplasms, the same carcinomas analyzed for gene expression were also examined for HE4 by immunohistochemistry on tissue microarrays (see below). (nature.com)
Molecular2
- Undoubtedly, advances in molecular biology will allow scientists to determine the exact genomic aberration responsible for each specific neoplasm. (medscape.com)
- Using a combination of molecular dynamics (MD) simulations and small-angle X-ray scattering (SAXS), we discovered an allosteric interface between the SH2 and kinase domain required for Btk activation and to which multiple XLA mutations map. (rcsb.org)
Arises1
- The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
Histology1
- A review of 155 cases of primary synovial chondromatosis by McCarthy et al identified only four cases of aggressive behavior and chondrosarcomalike histology (one in the elbow and three in the hip). (medscape.com)
Disease2
- Several of the recurrent lesions that showed junctional melanocytic components were considered primary melanomas and it was suggested that L-Dopa was responsible for malignant transformation of nevi and for rapid progression of the disease. (nih.gov)
- The common causes of unilateral abducens nerve palsy are neoplasm and vascular disease in middle-aged people [ 1 ]. (hindawi.com)
Factors2
- Multiple geenetic and environmental factors have been linked to the development of CRC. (mindmeister.com)
- The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause. (lookformedical.com)
Hypertension1
- 1 in Europe, hypertension is one of the most common interventions in primary care, and CCBs are a first-line treatment for this. (bmj.com)
MESH1
- Multiple Endocrine Neoplasia Type 2b" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Malignancy1
- This association may not be fortuitous and suggests that patients with multiple hamartomas of the perifollicular connective tissue should be examined periodically for intestinal polyps before malignancy develops. (nih.gov)
Metastatic1
- 11 Lee EJ, Chung HW, Jo JH, So Y. Radioembolization for the treatment of primary and metastatic liver cancers. (thieme-connect.com)
Genes3
- Our data show that, in contrast to adult MDS, Ras/MAPK pathway mutations are common in pediatric MDS (45% of primary cohort), while mutations in RNA splicing genes are rare (2% of primary cohort). (nature.com)
- Multiple large cohort studies of adult MDS patients found recurrent mutations in genes important in epigenetic regulation (e.g. (nature.com)
- We show that Ras/MAPK pathway mutations are common in pediatric primary MDS (45%) while mutations in RNA splicing genes are rare (2%), and that germline SAMD9/SAMD9L mutations are present in 17% of primary MDS patients. (nature.com)
Rectum1
- CRC is a neoplasm that develops in the colon or rectum. (mindmeister.com)
Colon5
- Multiple primary carcinomata of the colon duodenum and larynx associated with keratoacanthoma of the face. (meduniver.com)
- Colonoscopy showed multiple irregular ulcers in colon. (frontiersin.org)
- The resected specimen showed multiple perforations of the colon. (frontiersin.org)
- In this paper, we describe a very rare case of ENKTL involving the colon with multiple intestinal perforations. (frontiersin.org)
- A total of three colonoscopes and biopsies were performed for the patient, and the results showed multiple irregular ulcers in the whole colon ( Figure 1 ). (frontiersin.org)
Cranial3
- Multiple cranial nerve deficits or bilateral abducens nerve palsy associated with ENKL have been reported [ 3 ], but isolated unilateral abducens palsy is rarely reported. (hindawi.com)
- Neoplasms involving the brain stem may result in cranial nerve deficits. (vin.com)
- Direct lateral radiography of the skull of the patient, showing multiple punched out lytic lesions of the cranial vault, with no evidence of a periosteal reaction. (bmj.com)