• PROTEINS
  • Despite being one of the most studied proteins in biology, its physiological function is not yet conclusively established: mice genetically engineered to lack myoglobin can be viable and fertile but show many cellular and physiological adaptations to overcome the loss. (wikipedia.org)
  • isolate
  • I was wondering today whether it would be possible to isolate myoglobin from the blood of a deep diving sea mammal, and cultivate it to inject into humans - therefore giving us a possibility of staying underwater longer - a helpful remedy for one of the harry potter tasks in the 4th film/book! (thenakedscientists.com)
  • Until the gift of the sperm whale meat, Kendrew couldn't isolate enough myoglobin to grow crystals of sufficient size for his research. (si.edu)
  • Stability
  • Chow CJ, Ochiai Y, Watabe S, Hashimoto K (1989) Reduced stability and accelerated autoxidation of tuna myoglobin in association with freezing and thawing. (springer.com)
  • resembles
  • Globin E: a globin responsible for storing and delivering oxygen to the retina in birds Globin-coupled sensors: chimeric, with an N-terminal myoglobin-like domain and a C-terminal domain that resembles the cytoplasmic signalling domain of bacterial chemoreceptors. (wikipedia.org)
  • available
  • If the myoglobin test is available, it may be ordered to assess persons with chest pain who are suspected of having a heart attack. (labcorp.com)
  • heart
  • When heart or skeletal muscle is injured, myoglobin is released into the blood. (labcorp.com)
  • Sometimes, a myoglobin blood test may be used along with a troponin test as a cardiac biomarker to help detect a heart attack early, but in the U.S., it is used less frequently for this purpose. (labcorp.com)
  • An increase in myoglobin is detectable sooner than troponin, but it is not as specific for heart damage and it will not stay elevated as long as troponin. (labcorp.com)
  • Although a negative myoglobin result effectively rules out a heart attack, a positive result must be confirmed by testing for troponin. (labcorp.com)
  • Myoglobin is not widely used for diagnosing heart attacks because it has largely been replaced by Troponin, which is much more specific. (labcorp.com)
  • Flögel U, Fago A, Rassaf T (2010) Keeping the heart in balance: the functional interactions of myoglobin with nitrogen oxides. (springer.com)
  • Myoglobin is a sensitive marker for muscle injury, making it a potential marker for heart attack in patients with chest pain. (wikipedia.org)
  • take
  • similarly, myoglobin can take the forms of oxymyoglobin (MbO2), carboxymyoglobin (MbCO), and metmyoglobin (met-Mb). (wikipedia.org)
  • work
  • It's important to highlight that the behaviour of myoglobin doesn't work in the same way, as 2,3-BPG has no effect on it. (wikipedia.org)
  • hours
  • Blood levels of myoglobin can rise very quickly with severe muscle damage and can be measured within a few hours following an injury. (labcorp.com)