• Researchers did not have information on subjective outcomes such as nonfatal myocardial infarction . (medscape.com)
  • Myocardial rupture occurs in the setting of acute myocardial infarction (AMI),11 blunt and penetrating cardiac trauma, primary cardiac infection, primary and secondary cardiac tumors, infiltrative diseases of the heart, and aortic dissection. (medscape.com)
  • Ischemic myocardial rupture after acute myocardial infarction (AMI) may involve left ventricular (LV) and right ventricular (RV) free walls, ventricular septum, and LV papillary muscle, in decreasing order of frequency. (medscape.com)
  • This week it highlights hospitalizations rates for coronary atherosclerosis and acute myocardial infarction for the period 1996-2005. (cdc.gov)
  • Segment-Elevation Myocardial Infarction," published in the February 1, 2019, issue of the American Journal of Cardiology. (cdc.gov)
  • management of ST-segment-elevation myocardial infarction (STEMI) patients, and primary percutaneous coronary intervention (PCI) is the preferred reperfusion therapy when first-medical-contact-to-balloon time is within 90 minutes for patients admitted directly to a PCI-capable hospital and 2 hours for patients transferred to a PCI-capable hospital. (cdc.gov)
  • Pre-hospital transport times and outcomes after different reperfusion strategies for ST-elevation myocardial infarction. (cdc.gov)
  • ABSTRACT This study in May 2002, part of the Jordan Department of Statistics national cross- sectional, multistage employment and unemployment survey, measured the prevalence of self- reported myocardial infarction (MI) and the association with modifiable risk factors among Jordanians aged 40+ years. (who.int)
  • These analyses fail to account for the time course of the short-run cost savings from the rapid decline in risk of acute myocardial infarction (AMI) and stroke. (who.int)
  • Observational studies suggest associations between extremes of sleep duration and myocardial infarction (MI), but the causal contribution of sleep to MI and its potential to mitigate genetic predisposition to coronary disease is unclear. (nih.gov)
  • Background: Recent studies demonstrate that prothrombotic antiphospholipid antibodies (aPL) are overrepresented in patients with myocardial infarction (MI) due to coronary artery disease (MICAD). (lu.se)
  • The treatment of myocardial infarction has evolved considerably over the past decades. (bmj.com)
  • 1 Most attention, however, has been focused on treatments that may restore antegrade coronary blood flow in the culprit artery of the patient with evolving acute myocardial infarction. (bmj.com)
  • Angioplasty for acute myocardial infarction was first described as a rescue treatment in the case of failed intracoronary thrombolysis, and was studied extensively as adjunctive therapy, performed immediately (within hours), early (within 1-2 days), late (after two days), or elective for inducible ischaemia and/or postinfarction angina, after intravenous thrombolytic treatment. (bmj.com)
  • 2 It can be applied as an alternative reperfusion therapy in candidates for thrombolytic treatment, and is the only reperfusion option in many patients with acute myocardial infarction ineligible for thrombolytic treatment. (bmj.com)
  • The cardioprotective effects of Nar are well documented in the healthy state, in myocardial infarction, and in daunorubicin-, doxorubicin-, and high-glucose-induced cardiotoxicity [ 2 , 12 - 17 ]. (hindawi.com)
  • A preliminary study suggests that CTA can play the role cardiac MRI has been playing for detecting and quantifying myocardial infarction to estimate the potential success of coronary bypass graft surgery. (diagnosticimaging.com)
  • Delayed-enhancement and infarction volumes over total myocardial volume were evaluated by two radiologists using a 19-segment model for dual-source CT and cardiac MR. Ventricular function measures were also acquired using both techniques. (diagnosticimaging.com)
  • Paris, France - Aug. 30, 2011: Primary PCI is the best reperfusion therapy for patients presenting with acute ST-elevation myocardial infarction. (escardio.org)
  • A survey from 2007/8 showed that only 40% of European patients with ST-elevation myocardial infarction are treated with primary PCI. (escardio.org)
  • OPTIMAL REPERFUSION IN STEMI (presentation on Stent for Life and abstract 83408: CJ Terkelsen et al, Primary percutaneous coronary intervention as a national reperfusion strategy in patients with ST-elevation myocardial infarction: eleven years of experience from the Western Denmark Heart Registry. (escardio.org)
  • Does aspirin consumption affect the presentation or severity of acute myocardial infarction? (nih.gov)
  • The present population-based study explores the possibility that aspirin consumption affects the presentation and severity of acute myocardial infarction (AMI), and hence the likelihood of clinical detection. (nih.gov)
  • A drug known to reduce mortality rate in heart failure patients has now been found very effective when administered early in patients following an acute (ST elevated) myocardial infarction. (medindia.net)
  • Eplerenone, a mineralocorticoid receptor antagonist (MRA), has already been investigated and licensed for the use in patients with heart failure post myocardial infarction, but has so far not been investigated following acute STEMI without ongoing heart failure. (medindia.net)
  • Cardiac troponin is recommended as the preferred biomarker for the diagnosis of myocardial infarction for risk stratification and for therapeutic guidance regarding anticoagulation therapy and invasive management. (aacc.org)
  • But is it the most important biomarker to consider when screening for myocardial infarction? (aacc.org)
  • So when you see a patient who has an elevated troponin and you do not see any evidence on the ECG for myocardial infarction, and he has no typical chest pain indicative of myocardial ischemia, you need to do additional testings. (aacc.org)
  • So a patient has to undergo a very sophisticated and careful workup since we know that an elevated troponin in those who do not rule myocardial infarction still have a high risk and need to be identified properly. (aacc.org)
  • Although aggregate data suggest a link between snowfall and myocardial infarction (MI), individual risk has yet to be assessed. (cmaj.ca)
  • This large international study in 20,000 individuals finds the annual rate for myocardial infarction was low 0.6% but that combination therapy increased the risk 26% per year. (natap.org)
  • combination antiretroviral therapy was associated with a 26 percent relative increase in the rate of myocardial infarction per year of exposure during the first four to six years of use. (natap.org)
  • In addition, the relative increase in the risk of myocardial infarction per year cannot be extrapolated beyond the duration of follow-up in the study…… …….the annual rate of myocardial infarction, even among those exposed to therapy for four to six years, was less than 0.6 percent, and only a portion of the apparent excess risk could be attributed to combination antiretroviral therapy. (natap.org)
  • Other known risk factors for myocardial infarction probably contributed to the occurrence of these events. (natap.org)
  • Hence, the substantial benefits of combination antiretroviral therapy continue clearly to outweigh the increased risk of myocardial infarction associated with this therapy. (natap.org)
  • Conversely, significant contributions from diabetes, hypertension, and lipodystrophy were not identified…… we found no evidence to suggest that the duration of HIV-1 infection, the level of prior immunodeficiency, or the degree of HIV-1 RNA replication affected the association between exposure to therapy and the risk of myocardial infarction. (natap.org)
  • A marked decline in myocardial infarction (AMI) hospitalizations was observed worldwide during the COVID-19 outbreak. (mdpi.com)
  • Coronary angiography following acute myocardial infarction in Ontario, Canada. (ices.on.ca)
  • Methods - The temporal growth in the use of coronary angiography services and the use of statins after an acute myocardial infarction (AMI) was determined for all patients older than 65 years admitted to any hospital in Ontario, Canada, between 1992 and 2004. (ices.on.ca)
  • Background The circadian clock influences a number of cardiovascular (patho)physiological processes including the incidence of acute myocardial infarction. (bmj.com)
  • Objective To determine the impact of time-of-day onset of ST segment elevation myocardial infarction (STEMI) on infarct size. (bmj.com)
  • Acute myocardial infarction is myocardial necrosis resulting from acute obstruction of a coronary artery. (msdmanuals.com)
  • For non-ST-segment-elevation myocardial infarction, reperfusion is via percutaneous intervention or coronary artery bypass graft surgery. (msdmanuals.com)
  • Acute MI includes both non-ST-segment-elevation myocardial infarction (NSTEMI) and ST-segment-elevation myocardial infarction (STEMI). (msdmanuals.com)
  • Pathophysiology references Acute myocardial infarction is myocardial necrosis resulting from acute obstruction of a coronary artery. (msdmanuals.com)
  • Do you understand myocardial infarction and all the emergencies related to it? (proprofs.com)
  • To check your understanding, try this myocardial infarction MCQs with answers. (proprofs.com)
  • Otherwise and commonly known as a heart attack, Myocardial Infarction, abbreviated as MI, is when the blood decreases in the heart and stops. (proprofs.com)
  • Tissue plasminogen activator (tPA) is considered for treatment of a patient who arrives in the emergency department following onset of symptoms of myocardial infarction. (proprofs.com)
  • History of prior myocardial infarction. (proprofs.com)
  • Following myocardial infarction, a hospitalized patient is encouraged to practice frequent leg exercises and ambulate in the hallway as directed by his physician. (proprofs.com)
  • A patient arrives in the emergency department with symptoms of myocardial infarction, progressing to cardiogenic shock. (proprofs.com)
  • Cardiogenic shock is a serious complication of myocardial infarction with a high mortality rate. (proprofs.com)
  • Which of the following is the most common symptom of myocardial infarction? (proprofs.com)
  • What is Myocardial Infarction? (datasci.com)
  • Myocardial infarction (MI) occurs when the heart muscle is starved for oxygen long enough that cardiac cells die. (datasci.com)
  • Why Study Myocardial Infarction? (datasci.com)
  • How is Myocardial Infarction Studied? (datasci.com)
  • Several factors have been associated with an increased risk of developing ST elevation myocardial infarction (STEMI). (wikidoc.org)
  • Myocardial infarction ( MI ) or acute myocardial infarction ( AMI ), commonly known as a heart attack , results from the interruption of blood supply to a part of the heart, causing heart cells to die. (medicalxpress.com)
  • Classical symptoms of acute myocardial infarction include sudden chest pain (typically radiating to the left arm or left side of the neck), shortness of breath, nausea, vomiting, palpitations, sweating, and anxiety (often described as a sense of impending doom). (medicalxpress.com)
  • Immediate treatment for suspected acute myocardial infarction includes oxygen, aspirin, and sublingual nitroglycerin. (medicalxpress.com)
  • Objective To assess the association between off-hour (weekends and nights) presentation, door to balloon times, and mortality in patients with acute myocardial infarction. (bmj.com)
  • Study selection Any study that evaluated the association between time of presentation to a healthcare facility and mortality or door to balloon times among patients with acute myocardial infarction was included. (bmj.com)
  • 36 studies reported mortality outcomes for 1 892 424 patients with acute myocardial infarction, and 30 studies reported door to balloon times for 70 534 patients with ST elevation myocardial infarction (STEMI). (bmj.com)
  • Off-hour presentation for patients with acute myocardial infarction was associated with higher short term mortality (odds ratio 1.06, 95% confidence interval 1.04 to 1.09). (bmj.com)
  • Conclusion This systematic review suggests that patients with acute myocardial infarction presenting during off-hours have higher mortality, and patients with STEMI have longer door to balloon times. (bmj.com)
  • Acute myocardial infarction remains a leading cause of death worldwide. (bmj.com)
  • 1 Every year, approximately one million people in the United States have an acute myocardial infarction and 400 000 die from coronary heart disease. (bmj.com)
  • 2 Previous studies have suggested that patients with acute myocardial infarction who present to the hospital during off-hours (weekends and nights) may have higher mortality. (bmj.com)
  • 4 8 9 Because of the high incidence and case fatality of acute myocardial infarction, small increases in the relative risk of mortality during off-hours can translate to important effects in the population. (bmj.com)
  • THURSDAY, Feb. 3, 2022 (HealthDay News) -- Significantly faster declines in global cognition, memory, and executive function are seen following incident myocardial infarction (MI), according to a study presented at the American Stroke Association International Stroke Conference, held from Feb. 9 to 11 in New Orleans. (healthday.com)
  • Both corrected and persistent hyponatremia are predictors of all-cause mortality in patients presenting with myocardial infarction. (hcplive.com)
  • According to the authors of "Outcomes of Correcting Hyponatremia in Patients with Myocardial Infarction," published in Clinical Research in Cardiology , hyponatremia "has significant prognostic implications in patients with heart failure," but not much is known about the prognostic significance of hyponatremia in patients with myocardial infarction. (hcplive.com)
  • To evaluate the prognostic value of hyponatremia in patients with myocardial infarction (MI), and to assess the impact of managing hyponatremia on outcomes in patients with MI, the authors reviewed the records of 11,562 patients whose serum sodium levels were measured within 24 hours of admission and who were discharged from their institution with a diagnosis of myocardial infarction. (hcplive.com)
  • Based on these results, the authors wrote that "corrected and persistent hyponatremia in patients presenting with myocardial infarction is a predictor of all-cause mortality, major adverse cardiac events and heart failure-related 30-day rehospitalization. (hcplive.com)
  • Patients' data for the study were obtained from the EARLY-MYO-CMR (Early Assessment of Myocardial Tissue Characteristics by CMR in STEMI) registry, which was a prospective, multicenter registry of patients with ST-segment elevation myocardial infarction (STEMI) who underwent cardiac magnetic resonance (CMR) imaging after reperfusion therapy. (physiciansweekly.com)
  • A recent study discovered that shift employment causes myocardial infarction reperfusion damage. (physiciansweekly.com)
  • We aimed to summarize the evidence from randomized clinical trials studies examining the efficacy of ischemic postconditioning (IPost) in ST-elevation myocardial infarction. (dovepress.com)
  • Rapid, complete, and sustained reperfusion of the infarct-related coronary artery is a cornerstone in the treatment of acute ST-elevation myocardial infarction (STEMI). (dovepress.com)
  • This reduction can, in part, be attributed to better treatments, particularly in the acute phases of myocardial infarction (AMI). (oecd-ilibrary.org)
  • Among individuals who experience an acute myocardial infarction, approximately half will die of sudden death, and it often occurs outside of the hospital. (mdedge.com)
  • Many changes in the therapy of patients experiencing an acute myocardial infarction have occurred since that study began in 1979, including the use of thrombolytics, percutaneous coronary intervention, and coronary artery bypass surgery. (mdedge.com)
  • Well into the 1990s, fewer than 50% of patients who had experienced an acute myocardial infarction received that therapy. (mdedge.com)
  • Now, well over 90% of patients discharged from the hospital after an acute myocardial infarction are treated with β-blockers. (mdedge.com)
  • The NCQA has recently introduced a new measure to ensure continuing therapy after 6 months, after a study in 2006 indicated that only 71% of patients after an acute myocardial infarction were still receiving β-blockers. (mdedge.com)
  • The observations from Olmsted County place in perspective the success of the quality improvement process in mitigating mortality in acute myocardial infarction. (mdedge.com)
  • The main cause for the development of cardiogenic shock is the loss of myocardial function due to myocardial infarction leading to impaired left ventricular function with unstable haemodynamics and reduced systolic and mean arterial pressures. (cochrane.org)
  • Evidence from earlier published studies suggested that certain patients with acute myocardial infarction complicated by cardiogenic shock and treated by thrombolysis may derive benefit from a period of support with the IABP. (cochrane.org)
  • Intra-aortic balloon pump counterpulsation (IABP) is currently the most commonly used mechanical assist device for patients with cardiogenic shock due to acute myocardial infarction. (cochrane.org)
  • It is assessing whether the positron emission tomography (PET) tracer 18F-sodium fluoride is as a marker of coronary plaque vulnerability and can detect culprit and non-culprit unstable coronary plaques in patients with recent myocardial infarction. (ed.ac.uk)
  • The investigators intend to recruit 700 patients hospitalised with myocardial infarction and proven multivessel coronary artery disease. (ed.ac.uk)
  • Zalunfiban acetate is under clinical development by CeleCor Therapeutics and currently in Phase III for Myocardial Infarction. (pharmaceutical-technology.com)
  • According to GlobalData, Phase III drugs for Myocardial Infarction have a 65% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. (pharmaceutical-technology.com)
  • Zalanfiban (RUC-4, zalunfiban acetate) is under investigation for the treatment of ST-segment elevated myocardial infarction and chronic coronary artery disease. (pharmaceutical-technology.com)
  • CeleCor Therapeutics (CeleCor) is a biotechnology company that focused on developing a first-point-of-contact therapy to improve the treatment of serious heart attacks and developed a point of care injectable to treat ST-segment elevated myocardial infarction. (pharmaceutical-technology.com)
  • HealthDay News) - Proton pump inhibitor (PPI) use is associated with increased risk of first-time ischemic stroke and myocardial infarction (MI), according to a study published online Oct. 12 in the Journal of Internal Medicine . (clinicaladvisor.com)
  • Long-term use of proton pump inhibitors, dose-response relationship, and associated risk of ischemic stroke and myocardial infarction. (clinicaladvisor.com)
  • Schisandra chinensis is a commonly used traditional Chinese medicine, which has been widely used in the treatment of acute myocardial infarction in China. (frontiersin.org)
  • Cardiovascular disease, including atherosclerosis, myocardial infarction, heart failure and stroke, is the leading cause of morbidity and mortality in developed nations. (frontiersin.org)
  • Social status and subjective perceptions of 250 men after myocardial infarction. (cdc.gov)
  • Tenderness of the chest wall is reported in as many as 5% of patients who are diagnosed with myocardial infarction (MI). (medscape.com)
  • Medical management of acute ST elevation myocardial infarction. (medscape.com)
  • Intravenous thrombolysis in acute myocardial infarction. (medscape.com)
  • Costa e Silva R, Pellanda L, Portal V, Maciel P, Furquim A, Schaan B. Transdisciplinary approach to the follow-up of patients after myocardial infarction. (medscape.com)
  • The role of reperfusion therapy in paced patients with acute myocardial infarction. (medscape.com)
  • Third universal definition of myocardial infarction. (medscape.com)
  • American College of Cardiology/American Heart Association/European Society of Cardiology/World Heart Federation Universal definition of myocardial infarction classification system and the risk of cardiovascular death: observations from the TRITON-TIMI 38 Trial (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel-Thrombolysis in Myocardial Infarction 38). (medscape.com)
  • 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. (medscape.com)
  • Determinants of collateral development in patients with acute myocardial infarction. (medscape.com)
  • The repercussions of the occurrence of Acute Myocardial Infarction (AMI) extend beyond hospital discharge articulating chronic treatment and changes in lifestyle, and may promote the mobilization of the patient's support network. (bvsalud.org)
  • Anticoagulants and myocardial infarction : a reappraisal / edited by T. W. Meade. (who.int)
  • 100 Patients of acute myocardial infarction treated in an intensive coronary care unit. (who.int)
  • Datey KK, Nathwani AN, Shah RM, Deshmukh MM. 100 Patients of acute myocardial infarction treated in an intensive coronary care unit. (who.int)
  • Among patients with diabetes and without known coronary artery disease and referred for myocardial perfusion imaging, 12.7% had significant ischemia, and 60% had reduced myocardial blood flow reserve (MBFR) including those without symptoms of ischemia. (medscape.com)
  • Myocardial ischemia occurs when blood flow to your heart is reduced, preventing the heart muscle from receiving enough oxygen. (sparrow.org)
  • Myocardial ischemia, also called cardiac ischemia, reduces the heart muscle's ability to pump blood. (sparrow.org)
  • Myocardial ischemia might also cause serious abnormal heart rhythms. (sparrow.org)
  • Treatment for myocardial ischemia involves improving blood flow to the heart muscle. (sparrow.org)
  • Making heart-healthy lifestyle choices is important in treating and preventing myocardial ischemia. (sparrow.org)
  • Some people who have myocardial ischemia don't have any signs or symptoms (silent ischemia). (sparrow.org)
  • Myocardial ischemia occurs when the blood flow through one or more of your coronary arteries is decreased. (sparrow.org)
  • Myocardial ischemia can develop slowly as arteries become blocked over time. (sparrow.org)
  • Atherosclerosis is the most common cause of myocardial ischemia. (sparrow.org)
  • The clot might block an artery and lead to sudden, severe myocardial ischemia, resulting in a heart attack. (sparrow.org)
  • Coronary artery spasm is an uncommon cause of myocardial ischemia. (sparrow.org)
  • Type 1 and type 2 diabetes are linked to an increased risk of myocardial ischemia, heart attack and other heart problems. (sparrow.org)
  • People who get regular aerobic exercise have better heart health, which is associated with a lower risk of myocardial ischemia and heart attack. (sparrow.org)
  • Second, we describe the role of clinical settings such as acute or chronic myocardial ischemia, as initiators of pathways of endogenous myocardial regeneration. (wjgnet.com)
  • Persistent myocardial ischemia and hypoxia will cause malignant cardiac remodeling and subsequent heart failure. (hindawi.com)
  • Alpha adrenergic contributions to dysrhythmia during myocardial ischemia and reperfusion in cats. (jci.org)
  • Thus, enhanced alpha-adrenergic responsiveness occurs during myocardial ischemia and appears to be primary mediator of the electrophysiological derangements and resulting malignant dysrhythmias induced by catecholamines during myocardial ischemia and reperfusion. (jci.org)
  • To evaluate the effects of dexmedetomidine on myocardial ischemia-reperfusion injury in rats and its anti-apoptotic role, as well as the mechanism by which it regulates Janus kinase 2/signal transducers and activators of transcription 3 signal. (ijpsonline.com)
  • The left anterior descending coronary artery was ligated to construct the model of myocardial ischemia-reperfusion. (ijpsonline.com)
  • Dexmedetomidine pretreatment can obviously relieve myocardial ischemia-reperfusion injury and cardiomyocyte apoptosis in rats probably by activating the Janus kinase 2/signal transducers and activators of transcription 3 signaling pathway. (ijpsonline.com)
  • As asymptomatic myocardial ischemia (MI) is frequent in diabetes, we hypothesized that DPN may be associated with MI in patients with type 2 diabetes mellitus and no history of cardiovascular events. (springer.com)
  • All subjects underwent Technetium-99 m sestamibi single-photon emission computed tomographic imaging for the estimation of myocardial ischemia, expressed as Summed Stress Score (SSS). (springer.com)
  • Diabetes is a pivotal cause of asymptomatic myocardial ischemia (MI) even in the absence of coronary artery disease [ 3 ]. (springer.com)
  • Epigastric or chest symptoms from myocardial ischemia may incorrectly be attributed to a gastrointestinal (GI) source. (medscape.com)
  • Additionally, patients with myocardial ischemia may report relief or improvement with GI remedies (eg, antacids). (medscape.com)
  • The discomfort of myocardial ischemia may also erroneously be attributed to a musculoskeletal etiology. (medscape.com)
  • This retrospective, observational study included 2730 consecutive patients with diabetes and without known coronary artery disease treated in a large health system in the bi-state Kansas City metro area during 2010-2016 who underwent pharmacologic rest/stress myocardial perfusion imaging (MPI) using rubidium-82 positron emission tomography . (medscape.com)
  • What is a myocardial perfusion imaging test? (heart.org)
  • Myocardial perfusion imaging (MPI) is a non-invasive imaging test that shows how well blood flows through your heart muscle. (heart.org)
  • Establishing the feasibility of perfusion CT to do what cardiac MRA does for delayed-enhancement myocardial imaging could eliminate the need for cardiac MRA in this important function and help speed therapy decision-making for surgical candidates. (diagnosticimaging.com)
  • Myocardial rupture (or perforation) may also occur iatrogenically during percutaneous cardiac procedures (including device implantation) or open heart surgery (particularly valve replacement). (medscape.com)
  • Blunt cardiac trauma, most commonly occurring in the setting of an automobile accident, may cause myocardial rupture as a result of cardiac compression between the sternum and the spine, direct impact on the heart (sternal trauma), or deceleration injury. (medscape.com)
  • Delayed myocardial rupture has been reported as a result of cardiac contusion. (medscape.com)
  • Acute mitral or tricuspid regurgitation, VSD, or pericardial tamponade may result from myocardial rupture secondary to blunt cardiac trauma. (medscape.com)
  • Considering the complex nature of the adult heart, it is no wonder that innate regenerative processes, while maintaining adequate cardiac function, fall short in myocardial jeopardy. (wjgnet.com)
  • Because aging has been demonstrated to be directly related to the occurrence of cardiac disorders, together, the data have prompted us to investigate the effects of Nar in a cellular model of aged myocardial cells. (hindawi.com)
  • Although CP-BOLD looks similar to standard CINE, changes in myocardial intensity patterns and shape across cardiac phases, due to the heart's motion, BOLD effect and artifacts affect the underlying mechanisms of fully supervised segmentation techniques resulting in a significant drop in segmentation accuracy. (springer.com)
  • Cardiac troponin is a cardio specific protein that is detectable in the blood of patients with myocardial injury with sensitive and specific assays. (aacc.org)
  • You need to do cardiac ultrasounds to understand his myocardial function, and if he has shortness of breath, you need to do a CT scan to exclude pulmonary embolism. (aacc.org)
  • BACKGROUND Myocardial mass is a key determinant of cardiac muscle function and hypertrophy. (uni-muenchen.de)
  • Myocardial depolarization leading to cardiac muscle contraction is reflected by the amplitude and duration of the QRS complex on the electrocardiogram (ECG). (uni-muenchen.de)
  • Rho-kinase inhibition reduced significantly blood pressure, cardiac hypertrophy, myocardial collagen and macrophage infiltration, but not aortic wall hypertrophy. (portlandpress.com)
  • A significant correlation was found between PBMC Rho-kinase activity and cardiac remodeling, specifically with hypertrophy ( r = 0.51, P ≤0.01), myocardial collagen ( r = 0.40, P ≤0.05) and ED1 immunostaining ( r = 0.48, P ≤0.01). (portlandpress.com)
  • Through the network analysis, reduction of cardiac preload and myocardial contractility was shown to be the major effect of Schisandra components, which was further experimentally validated. (frontiersin.org)
  • Both hemodynamic factors (increased intracavitary pressure) and regional myocardial structural weakness (myocyte necrosis, collagen matrix resolution, and intense inflammation) can make important contributions to myocardial rupture in the setting of AMI. (medscape.com)
  • For the end point infarct size, estimated by biomarkers of myocardial necrosis, an overall pooled effect was SMD =−0.58, 95% CI: −0.96 to −0.19. (dovepress.com)
  • myocardial necrosis. (cdc.gov)
  • Abnormal QRS amplitude or duration reflect changes in myocardial mass and conduction, and are associated with increased risk of heart failure and death. (uni-muenchen.de)
  • When Asian dust clouds blow in to Japan's Kumamoto Prefecture, hospitals in the region handle a surge of acute myocardial infarctions (AMI) in the following 24 hours, and now a new prediction tool could help pinpoint which patients are at greatest risk. (escardio.org)
  • In the US, about 1.0 million myocardial infarctions occur annually. (msdmanuals.com)
  • Approximately one-quarter of all myocardial infarctions are "silent", that is without chest pain or other symptoms. (medicalxpress.com)
  • A severe myocardial contusion may lead to signs and symptoms of a heart attack. (medlineplus.gov)
  • Relationship between regional myocardial blood flow and thallium-201 distribution in the presence of coronary artery stenosis and dipyridamole-induced vasodilation. (jci.org)
  • Regional myocardial blood flow was measured during control conditions with radioisotope-labeled microspheres, and the phasic reactive hyperemic response to a 20-s transient occlusion was then recorded. (jci.org)
  • 5 min later, the animals were sacrificed, the left ventricle was sectioned into 1-2-g samples, and thallium-201 activity and regional myocardial blood flow were measured. (jci.org)
  • During the dipyridamole infusion, the increases in phasic blood flow, the distributions of regional myocardial blood flow, and the relationships between thallium-201 localization and regional blood flow were comparable to values previously observed in exercising dogs with similar occlusions. (jci.org)
  • These data provide basic validation that supports the use of intravenous dipyridamole and thallium-201 as an alternative to exercise stress and thallium-201 for evaluating the effects of coronary occlusive lesions on the distribution of regional myocardial blood flow. (jci.org)
  • The advanced echocardiography technique called myocardial work (MW), through the analysis of the left ventricular pressure - strain loop, is among the possibilities for evaluating these individuals. (bvsalud.org)
  • A myocardial bridge (MB) is a congenital heart defect in which one of the coronary arteries tunnels through the heart muscle itself (myocardium). (wikipedia.org)
  • However, if a band of muscle forms around one of the coronary arteries during the fetal stage of development, then a myocardial bridge is formed - a "bridge" of heart muscle over the artery. (wikipedia.org)
  • Penetrating myocardial injury occurs most commonly as a result of stab or gunshot wounds (see the image below). (medscape.com)
  • Myocardial bridging is a congenital anomaly in which the arteries that feed the muscles of the heart form inside the heart muscle instead of on the outer surface. (luriechildrens.org)
  • CONCLUSIONS Taken together, our findings provide new insights into genes and biological pathways controlling myocardial mass and may help identify novel therapeutic targets. (uni-muenchen.de)
  • Alternative sympatholytic interventions including pretreatment with 6-hydroxydopamine to deplete myocardial norepinephrine from 8.8 +/- 1.4 to 0.83 +/- 0.2 ng/mg protein and render the heart unresponsive to tyramine (120 microgram/kg) attenuated dysrhythmias induced by both coronary occlusion and reperfusion in a fashion identical to that seen with alpha-receptor blockade. (jci.org)
  • Intracoronary methoxamine (0.1 microM) in animals depleted of myocardial catecholamines by 6-hydroxydopamine pretreatment did not affect idioventricular rate before coronary occlusion. (jci.org)
  • OBJECTIVES This meta-analysis sought to gain insights into the genetic determinants of myocardial mass. (uni-muenchen.de)
  • Evaluation of myocardial work in patients with resistant arterial hypertension. (bvsalud.org)
  • Synthetic generation of myocardial blood-oxygen-level-dependent MRI time series via structural sparse decomposition modeling. (springer.com)
  • Myocardial contusion is a bruise of the heart muscle. (medlineplus.gov)
  • Mechanism investigations revealed a unique nuclear receptor subfamily 1 group D member 1/cardiotrophin-like cytokine factor 1 axis in the heart, which was critical in mediating the negative effects of shift work on myocardial damage. (physiciansweekly.com)
  • 26 weeks of treatment with empagliflozin reduced the myocardial glucose metabolic rate by 45.1% in patients with type 2 diabetes. (consultantlive.com)
  • Treatment with empagliflozin was linked to a significant reduction in the myocardial glucose metabolic rate in patients with type 2 diabetes (T2D) without coronary artery disease, according to recent findings. (consultantlive.com)
  • The study, " Effects of 26 weeks of treatment with empagliflozin vs glimepiride on the myocardial glucose metabolic rate in patients with type 2 diabetes: The randomized, open-label, crossover, active-comparator FIORE trial ," was published in Diabetes, Obesity and Metabolism . (consultantlive.com)
  • The clinical presentation of myocardial rupture depends on the mechanism and site of injury and the hemodynamic effects of the rupture. (medscape.com)
  • Artificial neural networks can detect coronary artery disease in myocardial bull\u2019s-eye scintigrams with such a high accuracy that the application of neural networks as clinical decision support tools appears to have significant potential. (lu.se)
  • Third, the hitherto conducted clinical studies that examined different approaches of initiating endogenous myocardial regeneration in failing human hearts are analyzed. (wjgnet.com)
  • The purpose of the present study was to develop a computer-based method for automatic detection and localization of coronary artery disease in myocardial bull's-eye scintigrams. (lu.se)
  • This study assesses the relationship between the distribution of thallium-201 and myocardial blood flow during coronary vasodilation induced by intravenous dipyridamole in canine models of partial and complete coronary artery stenosis. (jci.org)
  • The discomfort of myocardial ischemia may also erroneously be attributed to a musculoskeletal etiology. (medscape.com)
  • 6-Gingerol (6-G) is known to alleviate myocardial ischemia/reperfusion injury. (hindawi.com)
  • Myocardial ischemia/reperfusion injury (MIRI) causes damage to the function, metabolism, and structure of the heart. (hindawi.com)
  • Schematic of proposed mechanism of myocardial ischaemic. (researchgate.net)
  • The presence of normal or non-obstructive coronary lesions would suggest possibility of different mechanism of myocardial necrosis. (lww.com)
  • 2001). Histopathology of myocardial damage in experimental fluorosis in rabbits. (fluoridealert.org)
  • These involve the activation of Jak/STAT3 and PI3K/Akt, which subsequently decreases mitochondrial permeability transition pore (mPTP) opening and increases mitochondrial K ATP (Mito K ATP ) channel opening, which attenuates myocardial ischaemia reperfusion injury. (researchgate.net)
  • Myocardial ischaemia reperfusion injury is the leading cause of death in patients with cardiovascular disease. (researchgate.net)
  • Interventions such as ischaemic pre and postconditioning protect against myocardial ischaemia reperfusion injury. (researchgate.net)
  • as a feasible method for reduction of myocardial ischaemia-reperfusion (IR) injury. (researchgate.net)
  • Myocardial fibrosis can develop as a consequence of myocardial ischaemia and is present in 16-55% of sudden cardiac deaths (Davies and Popple 1979). (forensicmed.co.uk)
  • In the US, about 1.0 million myocardial infarctions occur annually. (msdmanuals.com)
  • But the great majority of myocardial infarctions are not fatal, whether treated or untreated. (onteenstoday.com)
  • prolonged ingestion of fluoride through drinking water, particularly with high doses, induced significant histopathological and biochemical changes leading to myocardial tissue damage. (fluoridealert.org)
  • It is believed that fluoride toxicity is brought about by oxidative stress and, thus, the probably interaction between fluoride and the myocardial metabolism can be responsible for histopathological and biochemical changes in myocardial tissue. (fluoridealert.org)
  • Project Goals The goal of the project is to develop a myocardial biopsy catheter of materials safe for MRI operation yet sufficiently sharp to extract myocardial tissue effectively. (sbir.gov)
  • We developed two engineered cardiac grafts, based on decellularized scaffolds from myocardial and pericardial tissues and repopulated them with adipose tissue mesenchymal stem cells (ATMSCs). (nature.com)
  • In hypertensive heart disease, reactive myocardial fibrosis represents as an excessive accumulation of fibrillar collagen within the normal connective tissue structures of the myocardium. (springer.com)
  • The fact, that the myocardium of both ventricles is involved, irrespective of ventricular loading conditions, suggests that circulating factors, and not the hemodynamic load are primary responsible for this adverse response of the myocardial fibrous tissue. (springer.com)
  • In contrast, PGE 2 , which would be elevated in myocardial tissue after angiotensin-converting enzyme inhibition, counteracts the fibrotic effects of the RAAS on myocardial tissue. (springer.com)
  • Factor SM, Zhao MJ, Eng C, Robinson TF (1988) The effects of acutely increased ventricular cavity pressure on intrinsic myocardial connective tissue. (springer.com)
  • CONCLUSIONS: Myocardial edema is present in cardiac amyloidosis by histology and cardiovascular magnetic resonance T2 mapping. (ucl.ac.uk)
  • 2018 ESC/EACTS Guidelines on myocardial revascularization. (qmul.ac.uk)
  • Myocardial metabolism for the toxicologist. (nih.gov)
  • Image-guided myocardial biopsy using MRI might enhance the diagnostic utility and safety of myocardial biopsy in inflammatory or infiltrative cardiomyopathies. (sbir.gov)
  • This solicitation aims to support the development of an MRI myocardial biopsy forceps and accessories for commercial clinical availability. (sbir.gov)
  • A phase I award would develop and test functioning MRI myocardial biopsy forceps system, including accessories, in vivo. (sbir.gov)
  • Myocardial biopsy is the removal of a small piece of heart muscle for examination. (mountsinai.org)
  • Myocardial biopsy is done through a catheter that is threaded into your heart ( cardiac catheterization ). (mountsinai.org)
  • Histological evidence of edema was present in 87.5% of biopsy samples ranging from 5% to 40% myocardial involvement. (ucl.ac.uk)
  • Epigastric or chest symptoms from myocardial ischemia may incorrectly be attributed to a gastrointestinal (GI) source. (medscape.com)
  • A severe myocardial contusion may lead to signs and symptoms of a heart attack. (medlineplus.gov)
  • It also induces myocardial apoptosis, inflammatory response, and oxidative stress resulting in severe arrhythmia, cardiac failure, and even sudden cardiac death [ 4 ]. (hindawi.com)
  • In various experimental in vivo models, it has been shown that myocardial fibrosis is always associated with activation of circulating or local renin-angiotensin-aldosterone systems (RAAS). (springer.com)
  • Thus cardiac fibroblast function is modulated by either effector hormone of the RAAS, AngII and ALDO, via specific receptors that lead to progressive myocardial fibrosis in disease states where circulating or local RAAS is activated, i.e., in hypertensive heart disease. (springer.com)
  • Objective: We extended those findings by analyzing the kinetic profile of salivary and serum biomarker profiles in patients undergoing alcohol septal ablation and percutaneous coronary intervention (PCI) as models of acute myocardial injury. (umich.edu)
  • Percutaneous coronary intervention (PCI) and thrombolytic therapy can recover myocardial blood supply in timely manner. (hindawi.com)
  • The most important aim is to spread the Working Group mission into the new generation of researchers and clinicians interested in the field of the myocardial and pericardial diseases. (escardio.org)
  • The Young in career will work within the Working Group on myocardial and pericardial diseases, contributing to its activities to fulfill its aims and share its mission. (escardio.org)
  • Collectively, engineered cardiac grafts -with pericardial or myocardial scaffolds- were effective in restoring cardiac function post-MI, and pericardial scaffolds showed better structural integrity and recolonization capability. (nature.com)
  • The aim of our study was to assess whether transitory nutritional risk after heart surgery influences on the left ventricle myocardial mass (LVMM), assessed by echocardiography. (karger.com)
  • Alternative sympatholytic interventions including pretreatment with 6-hydroxydopamine to deplete myocardial norepinephrine from 8.8 +/- 1.4 to 0.83 +/- 0.2 ng/mg protein and render the heart unresponsive to tyramine (120 microgram/kg) attenuated dysrhythmias induced by both coronary occlusion and reperfusion in a fashion identical to that seen with alpha-receptor blockade. (jci.org)
  • To evaluate the reliability of [ 123 I]meta-iodobenzylguanidine (MIBG) myocardial scintigraphy for diagnosing Parkinson's disease (PD). (bmj.com)
  • However, the underlying molecular mechanisms of 6-G myocardial protection are not known. (hindawi.com)
  • Rats were subjected to I/R in the presence or absence of 6-G and the changes of cardiac function, infarct size and histopathological changes, and the levels of cardiac troponin T, creatine kinase-MB, and myocardial apoptosis were examined. (hindawi.com)
  • We found that 6-G (6 mg/kg) pretreatment significantly improved heart function and ameliorated infarct size and histopathological changes and cardiac troponin T and creatine kinase-MB levels induced by I/R. Moreover, pretreatment with 6-G significantly inhibited myocardial apoptosis and caspase-3 activation induced by I/R. 6-G also upregulated expression of PI3K, p-Akt, and Akt in myocardial tissues. (hindawi.com)
  • 2011). Chronic fluoride toxicity and myocardial damage: antioxidant offered protection in second generation rats. (fluoridealert.org)