• ischemic
  • 2 Ischemic preconditioning may also be an important adaptive response in humans in the setting of percutaneous transluminal coronary angioplasty with repeated inflations, 3 4 myocardial protection during coronary artery bypass graft surgery, 5 and preinfarction angina. (ahajournals.org)
  • calcium
  • Calcium-sensitizing agents exert a positive inotropic action by increasing the sensitivity of the myocardial contractile apparatus to calcium. (ahajournals.org)
  • demand
  • CO is regulated principally by the demand for oxygen by the cells of the body. (wikipedia.org)
  • The theory behind this approach is that by simultaneously limiting the oxygen demand and maximizing oxygen delivery to the heart after damage has occurred, the heart is more fully able to recover. (wikipedia.org)
  • tissue
  • Gaseous signaling molecules are gaseous molecules that are either synthesised internally (endogenously) in the organism, tissue or cell or are received by the organism, tissue or cell from outside (say, from the atmosphere or hydrosphere, as in the case of oxygen) and that are used to transmit chemical signals which induce certain physiological or biochemical changes in the organism, tissue or cell. (wikipedia.org)
  • The dead heart muscle is replaced by non-contractile fibrotic tissue, forming the myocardial scar. (wikipedia.org)
  • quiescence
  • The main goals of hypothermic cardioplegia are: Immediate and sustained electromechanical quiescence Rapid and sustained homogeneous myocardial cooling Maintenance of therapeutic additives in effective concentrations Periodic washout of metabolic inhibitors The most common procedure for accomplishing asystole is infusing cold cardioplegic solution into the coronary circulation. (wikipedia.org)
  • nitric oxide
  • Nitric oxide, known as the 'endothelium-derived relaxing factor', or 'EDRF', is biosynthesized endogenously from L-arginine, oxygen, and NADPH by various nitric oxide synthase (NOS) enzymes. (wikipedia.org)
  • A particularly important intermediate in the chemical industry, nitric oxide forms in mixtures of nitrogen and oxygen at high temperatures, as found in combustion systems such as internal-combustion piston engines, gas turbines, furnaces, and boilers. (wikipedia.org)
  • When exposed to oxygen, nitric oxide is converted into nitrogen dioxide. (wikipedia.org)
  • In water, nitric oxide reacts with oxygen and water to form HNO2 or nitrous acid. (wikipedia.org)
  • The nitric oxide reacts with the ozone to produce oxygen and nitrogen dioxide, accompanied with emission of light (chemiluminescence): ·NO + O3 → NO2 + O2 + hν which can be measured with a photodetector. (wikipedia.org)
  • Concentrations
  • Efaproxiral can be absorbed via transdermal, rectal, inhalation and gastrointestinal routes, though not at plasma concentrations great enough to alter the oxygen-haemoglobin dissociation curve. (wikipedia.org)