• Prehospital and emergency department management is focused on acute exacerbations of the symptoms of aortic stenosis. (medscape.com)
  • However, recent studies have supported increased catecholamine levels during psychosomatic stress are believed to result in development of acute myocardial stunning and LV wall motion abnormalities. (scirp.org)
  • Acute coronary syndrome 27. (muni.cz)
  • The autopsy listed "coronary atherosclerosis" followed by "stenosis, thrombosis, chronic myocardial infarct, subacute myocardial infarcts, acute myocardial infarct, and acute ischemic change" as the cause(s) of death. (cdc.gov)
  • O'Brien ER, Glover C, and Labinaz M. Acute Outcome with the Flexicut directional Coronary Atherectomy Catheter for the Treatment of Coronary In-Stent Restenosis. (ottawaheart.ca)
  • Objective To explore acute and late coronary outcomes and their risk/modifiers in patients with Kawasaki disease (KD). (bmj.com)
  • Main outcome measures The acute coronary severities and late outcomes (survival free of coronary aneurysm persistence and ischaemia) were assessed. (bmj.com)
  • Results Coronary arterial lesions occurred in 40.6% of cases at their acute febrile stages, and persisted beyond 1 month in 196 (18.3%, M/F=138/58) patients: 125 (11.6%) had small aneurysms, 44 (4.1%) had medium aneurysms, and 27 (2.5%) had giant aneurysms. (bmj.com)
  • With intravenous immunoglobulin therapy, the risk of coronary arterial lesions for patients with Kawasaki disease has been reduced from 20-25% to 5-10% during the acute stage. (bmj.com)
  • 1 Despite receiving intravenous immunoglobulin (IVIG) therapy, coronary arterial lesions (CALs) occurred in 5-20% of patients with KD during the acute stage. (bmj.com)
  • Overview of Acute Coronary Syndromes (ACS) Acute coronary syndromes result from acute obstruction of a coronary artery. (msdmanuals.com)
  • Revascularization for Acute Coronary Syndromes Revascularization is the restoration of blood supply to ischemic myocardium in an effort to limit ongoing damage, reduce ventricular irritability, and improve short-term and long-term outcomes. (msdmanuals.com)
  • 10 dogs were chronically instrumented with catheters in the left atrium and aorta and with a balloon occluder and electromagnetic flow probe on the proximal left circumflex coronary artery. (jci.org)
  • The left circumflex coronary artery was either partially occluded to reduce phasic blood flow to control values (group 1) or it was completely occluded (group 2), and thallium-201 and a second microsphere label were injected. (jci.org)
  • The results indicate that cardiac CT might be especially useful in patients with ACS but with pretended normal coronary arteries based on the results of conventional coronary angiography. (escardio.org)
  • A patient presenting with uncontrolled heart failure should be treated supportively with oxygen, cardiac and oximetry monitoring, intravenous access, loop diuretics, nitrates (remembering the potential nitrate sensitivity of patients with aortic stenosis), morphine (as needed and tolerated), and noninvasive or invasive ventilatory support (as indicated). (medscape.com)
  • Cardiac contractile dysfunction during mild coronary flow reductions is due to an altered calcium-pressure relationship in rat hearts. (jci.org)
  • Myocardial strain imaging uses speckle-tracking echocardiography to measure tissue deformation through the cardiac cycle. (medscape.com)
  • Cardiac imaging is central to the diagnosis and risk stratification of coronary artery disease, beyond symptoms and clinical risk factors, by providing objective evidence of myocardial ischaemia and characterisation of coronary artery plaque. (bmj.com)
  • New cardiac CT techniques can assess coronary artery inflammation by imaging perivascular fat, and this may represent an important step forward in identifying the 'residual risk' that is not detected by plaque or ischaemia imaging. (bmj.com)
  • Cardiac CT (CCT) imaging has transformed the detection, characterisation and stratification of coronary artery disease (CAD) risk in individuals. (bmj.com)
  • As the stenosis progresses, patients are unable to increase stroke volume, and as a result, they are unable to increase cardiac output so as to compensate for increases in myocardial oxygen demand. (medscape.com)
  • Myocardial fibrosis is a common postmortem finding among young individuals with sudden cardiac death. (onteenstoday.com)
  • Myocardial fibrosis is an important part of cardiac remodeling that leads to heart failure and death. (onteenstoday.com)
  • Nearly all etiologies of heart disease involve pathological myocardial remodeling characterized by excessive deposition of extracellular matrix (ECM) proteins by cardiac fibroblasts (CFs), which reduces tissue compliance and accelerates the progression to heart failure. (onteenstoday.com)
  • Transient ischemic dilation (TID) in the setting of abnormal stress-rest cardiac SPECT myocardial perfusion imaging (MPI) has been linked with increased cardiovascular risk. (snmjournals.org)
  • In this study, cardiac CT was used to evaluate the prevalence of atherosclerotic lesions and the severity of coronary artery stenosis in patients with TID of the left ventricle with or without associated myocardial perfusion defects on SPECT MPI. (snmjournals.org)
  • When compared with the TID-negative control cohort, TID-positive patients had no significant differences in the presence and extent of atherosclerosis, the degree of coronary artery stenosis, or the calcium score at cardiac CT. (snmjournals.org)
  • The presence of TID with an otherwise normal SPECT MPI study does not translate into a greater extent of coronary artery disease as assessed by cardiac CT or increased risk for future major adverse cardiac events. (snmjournals.org)
  • CTA is appropriate for coronary artery evaluation before non-coronary cardiac surgery as an equivalent alternative to invasive angiography in patients with low-to-intermediate probability of CAD and younger patients with primarily non-degenerative valvular conditions. (diagnosticimaging.com)
  • Late enhancement CT imaging may be appropriate to evaluate myocardial viability in some patients who cannot undergo cardiac MRI if it has the potential to impact diagnosis and treatment. (diagnosticimaging.com)
  • It is a catheter-based procedure which is performed by the interventional cardiologist and cardiac surgeon for patients with calcified, narrowed aortic valve (aortic valve stenosis). (yashodahospitals.com)
  • This novel, interventional procedure is undertaken in the Cardiac Catheterization Lab (Cath-lab) where procedures like coronary angioplasty are regularly performed. (yashodahospitals.com)
  • The survivor of aortic combined with cardiac injury, even coronary artery injury, are fewer. (hindawi.com)
  • Cardiac troponins T and I are widely used for the diagnosis of myocardial injury. (medscape.com)
  • Electronic Medical Record-Based Machine Learning Approach to Predict the Risk of 30-Day Adverse Cardiac Events After Invasive Coronary Treatment: Machine Learning Model Development and Validation. (cdc.gov)
  • CT-QCA identified 25 plaques in infarct-related coronary arteries. (escardio.org)
  • From this study, it is concluded tht the myocardium distal to a critical stenosis suffers a progressive reduction in flow during ventricular fibrillation which does not occur in regions supplied by unstenosed coronary arteries. (johnshopkins.edu)
  • The Leadership Council of the American College of Cardiology (ACC) recommends considering percutaneous coronary intervention (PCI) in all patients with significant proximal coronary stenosis in major coronary arteries before transcatheter aortic valve replacement (TAVR), even though the indication is not covered in current guidelines. (medscape.com)
  • Angina commonly arises from vasospasm of the coronary arteries. (wikipedia.org)
  • Lower levels of nitric oxide are present in spastic coronary arteries. (wikipedia.org)
  • In humans, the nitrate action of nicorandil dilates the large coronary arteries at low plasma concentrations. (wikipedia.org)
  • BACKGROUND: In the medical literature, several cases of Tako-tsubo cardiomyopathy (TTC) with coronary artery disease (CAD) have been reported, and in clinical practice, several typical TTC cases show relevant stenoses of the coronary arteries spatially unrelated to the dysfunctional myocardium. (who.int)
  • 50%) coronary stenosis not supplying the dysfunctional myocardium, whereas 407 patients (90.4%) had irrelevant stenosis or angiographically normal coronary arteries. (who.int)
  • EKG is appropriate for gate aortic dissection, aneurysm CTA, pulmonary embolus studies in men over age 45 and women over age 55, as well as analyze and report the coronary arteries. (diagnosticimaging.com)
  • 1. Relaxation and prevention of coronary artery spasm: Verapamil hydrochloride dilates the main coronary arteries and coronary arterioles, both in normal and ischemic regions, and is a potent inhibitor of coronary artery spasm, whether spontaneous or ergonovine-induced. (nih.gov)
  • This suggests that, in general, relief of spasm or dilation of coronary arteries is not an important factor in classical angina. (nih.gov)
  • Verapamil hydrochloride dilates the main coronary arteries and coronary arterioles, both in normal and ischemic regions, and is a potent inhibitor of coronary artery spasm, whether spontaneous or ergonovine-induced. (nih.gov)
  • That likely indicates a blockage (or partial blockage) in the coronary arteries that could lead to a heart attack. (radiologytoday.net)
  • Overview of Coronary Artery Disease Coronary artery disease (CAD) involves impairment of blood flow through the coronary arteries, most commonly by atheromas. (msdmanuals.com)
  • Automatic extraction of coronary arteries using deep learning in invasive coronary angiograms. (cdc.gov)
  • Multislice computed tomography (CT) can noninvasively identify the presence of coronary plaques even in the absence of significant coronary artery stenosis. (escardio.org)
  • OBJECTIVES: The purpose of this study was to compare myocardial contrast echocardiography (MCE) with single-photon emission computed tomography (SPECT) for the detection of significant coronary artery disease (CAD) in patients with symptoms suggestive of CAD. (northwestern.edu)
  • There are new recommendations for the use of coronary computed tomographic angiography (CCTA) from the Society of Cardiovascular Computed Tomography (SCCT). (diagnosticimaging.com)
  • Artificial intelligence evaluation of coronary computed tomography angiography for coronary stenosis classification and diagnosis. (cdc.gov)
  • Performance of machine learning-based coronary computed tomography angiography for selecting revascularization candidates. (cdc.gov)
  • Clinical Evaluation of the Automatic Coronary Artery Disease Reporting and Data System (CAD-RADS) in Coronary Computed Tomography Angiography Using Convolutional Neural Networks. (cdc.gov)
  • Thus, a more precise evaluation of coronary plaque might be obtained. (escardio.org)
  • CTA is appropriate for the evaluation of coronary anomalies. (diagnosticimaging.com)
  • Noninvasive CT evaluation of coronary lesion severity (by CTA) + hemodynamic significance (by CTP using a 320-row detector CT) was compared to invasive angiography + single photon emission CT (SPECT) and analyzed on a per-patient and per-vessel basis. (acc.org)
  • There are many thousands of patient-years of outcome data in the literature over the past few decades documenting the superiority of SPECT and PET-MPI [myocardial perfusion imaging] for prognostic evaluation of coronary heart disease and the assessment of effectiveness of lifestyle, medical, and revascularization therapies across a broad spectrum of clinical pretest risk. (radiologytoday.net)
  • Calcification of the aortic valve is found in almost all adults with hemodynamically significant aortic stenosis. (medscape.com)
  • Coronary angiography was performed which showed minimal coronary artery disease without a hemodynamically significant stenosis. (scirp.org)
  • That's important because the benefits of revascularization are highest in patients who have coronary stenoses that are flow-limiting and hemodynamically significant. (acc.org)
  • Investigators reported results of CORE320 at ESC 2012 and found that combined CTA and CTP was capable of detecting hemodynamically significant stenoses (50% or 70%), as defined by invasive angiography with an associated SPECT perfusion defect. (acc.org)
  • CONCLUSIONS: Myocardial contrast echocardiography is comparable to SPECT in the detection of CAD not only on a patient basis but also in the localization of disease by vascular territory in a relatively high-risk population. (northwestern.edu)
  • Coronary artery bypass grafting (CABG) and percutaneous transluminal coronary angioplasty (PTCA) are more effective than medical treatment for the management of ischaemic heart disease. (nih.gov)
  • Both CABG and PTCA improve the clinical status of symptomatic patients with single-vessel coronary artery disease. (nih.gov)
  • He is a PhD supervisor and researcher in the field of coronary calcification, and Doppler echocardiography in heart failure and valvular heart disease. (umu.se)
  • Currently the most active projects Michael Henein's Team is working on are coronary calcification, heart failure and valvular heart disease. (umu.se)
  • T1 and T2 mapping better characterize myocardial tissue by identifying areas of edema (T2), inflammation, and more diffuse fibrosis (T1), which may aid in diagnosing myocarditis without LGE, amyloidosis , hemochromatosis , and Fabry disease . (medscape.com)
  • However, coronary artery disease risk is also driven by biological processes, such as inflammation, that are not fully reflected by severity of stenosis, myocardial ischaemia or by coronary plaque features. (bmj.com)
  • Coronary artery disease risk assessment that incorporates clinical factors, plaque characteristics and perivascular inflammation offers a more comprehensive individualised approach to quantify and stratify coronary artery disease risk, with potential healthcare benefits for prevention, diagnosis and treatment recommendations. (bmj.com)
  • The aim of this study was to emphasize the impact of the aspartate aminotransferase-to-alanine aminotransferase ratio (De Ritis ratio) on the prognosis of patients with stable coronary artery disease (SCAD) undergoing percutaneous coronary intervention (PCI). (medscimonit.com)
  • Coronary heart disease, aortic stenosis and hypertension are the most frequent causes of myocardial fibrosis (13). (onteenstoday.com)
  • What kind of disease is myocardial fibrosis? (onteenstoday.com)
  • Myocardial fibrosis is a common final pathway in chronic myocardial disease and is the structural correlate of heart failure. (onteenstoday.com)
  • Previous studies have suggested that TID in the context of reversible myocardial perfusion defects is associated with increased risk of severe, extensive multivessel coronary artery disease (CAD) ( 1 , 6 , 7 ). (snmjournals.org)
  • 5) Behavior Questionnaire elicited data on behavior which may be associated with coronary heart disease for examined persons ages 25-74. (cdc.gov)
  • Overall, he said, "We found the addition of CT myocardial perfusion to CT angiography allows clinicians to distinguish between anatomic and flow limiting stenoses in patients with suspected coronary disease. (acc.org)
  • Coronary heart disease (CHD) causes many adverse cardiovascular events and poses a threat to the patient's health and quality of life. (wjgnet.com)
  • New York City has one of the highest reported death rates from coronary heart disease in the United States. (cdc.gov)
  • We conducted a cross-sectional validation study by using a random sample of death certificates that recorded in-hospital deaths in New York City from January through June 2003, stratified by neighborhoods with low, medium, and high coronary heart disease death rates. (cdc.gov)
  • We computed a comparability ratio (coronary heart disease deaths recorded on death certificates divided by validated coronary heart disease deaths) to quantify agreement between death certificate determination and clinical judgment. (cdc.gov)
  • Coronary heart disease appears to be substantially overreported as a cause of death in New York City among in-hospital deaths. (cdc.gov)
  • Coronary heart disease (CHD) is the leading cause of death for adults in the United States, and stroke ranks third (1). (cdc.gov)
  • Age-adjusted deaths from coronary heart disease in New York City (NYC) versus the United States overall. (cdc.gov)
  • Electrocardiogram-based deep learning algorithm for the screening of obstructive coronary artery disease. (cdc.gov)
  • Pre-test probability for coronary artery disease in patients with chest pain based on machine learning techniques. (cdc.gov)
  • Machine learning-enhanced echocardiography for screening coronary artery disease. (cdc.gov)
  • A machine-learning based bio-psycho-social model for the prediction of non-obstructive and obstructive coronary artery disease. (cdc.gov)
  • Development and evaluation of a radiomics model of resting N-ammonia positron emission tomography myocardial perfusion imaging to predict coronary artery stenosis in patients with suspected coronary heart disease. (cdc.gov)
  • A clinical decision support system for predicting coronary artery stenosis in patients with suspected coronary heart disease. (cdc.gov)
  • Study on the risk of coronary heart disease in middle-aged and young people based on machine learning methods: a retrospective cohort study. (cdc.gov)
  • Deep learning to detect significant coronary artery disease from plain chest radiographs AI4CAD. (cdc.gov)
  • Deep learning artificial intelligence framework for multiclass coronary artery disease prediction using combination of conventional risk factors, carotid ultrasound, and intraplaque neovascularization. (cdc.gov)
  • Coronary atherosclerotic disease is a leading cause of mortality and morbidity due to major cardiovascular events in the United States and abroad. (bvsalud.org)
  • Furthermore, combined CTA and CTP was superior to CTA alone for correctly identifying flow-limiting and functionally relevant obstructive CAD and predicted revascularization with accuracy similar to invasive coronary angiography + SPECT. (acc.org)
  • These data provide basic validation that supports the use of intravenous dipyridamole and thallium-201 as an alternative to exercise stress and thallium-201 for evaluating the effects of coronary occlusive lesions on the distribution of regional myocardial blood flow. (jci.org)
  • Although IVIG use improves the initial severity of coronary lesions, it does not further modify the long-term fate of coronary aneurysms. (bmj.com)
  • CTA provides morphologic information of coronary anatomy and is capable of detecting the presence of atherosclerotic lesions. (acc.org)
  • Intravascular imaging, using ultrasound (IVUS) or optical coherence tomography, reveals that angiographic assessment of the coronary lumen grossly underestimates the presence, nature and extent of coronary artery plaque. (bmj.com)
  • Cardiologists cannot solely rely on the angiographic appearance of epicardial coronary artery stenosis when evaluating patients with myocardial ischaemia. (rcpe.ac.uk)
  • We have carried out such a comparison in patients with isolated proximal left anterior descending artery stenosis, conserved left ventricular function, and documented ischaemia. (nih.gov)
  • Historically, evaluation of CAD was guided by symptoms, and crude measures of myocardial ischaemia with limited sensitivity and specificity from exercise ECG (ExECG) and other stress tests. (bmj.com)
  • First, two-dimensional imaging cannot assess haemodynamic consequences of stenoses, in terms of myocardial ischaemia. (bmj.com)
  • Among the patients with KD with coronary aneurysms, 10-year ischaemia event-free and aneurysm persistence probability was 87.5% and 20.6%, respectively. (bmj.com)
  • Myocardial contrast echocardiography is a new technique allowing bedside assessment of myocardial perfusion. (northwestern.edu)
  • Echocardiography is the preferred imaging test for aortic stenosis. (medscape.com)
  • Aortic stenosis is seen on 2-dimensional echocardiography. (medscape.com)
  • In 37 patients (age 58 +/- 9 years) with ischemic left ventricular dysfunction, myocardial viability was assessed using low-dose (10 microg/kg body weight per min) two-dimensional dobutamine stress echocardiography (DSE), tissue Doppler imaging, SRI and (18)F-fluorodeoxyglucose ((18)FDG) positron emission tomography (PET). (nih.gov)
  • The principal utility of CMR and its advantage over echocardiography for cardiomyopathy is its use of late gadolinium enhancement (LGE) , which visualizes myocardial tissue and detects scar, fibrosis, or infiltration. (medscape.com)
  • Coronary angiography revealed a disruption of the proximal left anterior descending artery with a 95% stenosis. (hindawi.com)
  • [ 2 ] In symptomatic patients with medically treated moderate to severe aortic stenosis, death usually occurs within 5 years. (medscape.com)
  • In truly asymptomatic patients with severe aortic stenosis, the issue of valve replacement is less clear. (medscape.com)
  • Patients with severe heart failure due to aortic stenosis that is resistant to medical management should be considered for urgent surgery. (medscape.com)
  • The high rate of restenosis and the absence of a mortality benefit preclude its use as a definitive treatment method in adults with severe aortic stenosis. (medscape.com)
  • She was diagnosed with severe stenosis of aortic valve, with extensive valve calcification. (yashodahospitals.com)
  • After failed coronary artery percutaneous transluminal angioplasty (PTA) and deteriorated aortic lesion, the ruptured aorta was subsequently successfully treated by us with a self-made individualized endograft. (hindawi.com)
  • [ 5 ] Finally, in 1977 Andreas Grüntzig performed the first percutaneous coronary angioplasty in a patient with angina pectoris and a stenosis of the left anterior coronary artery. (medscape.com)
  • Three dimensional cross-sectional imaging has been shown to help reduce procedural complications such as vascular access injury, paravalvular regurgitation, and coronary obstruction. (medscape.com)
  • Earlier it was believed that the reason for TCM was coronary artery spasm. (scirp.org)
  • This property increases myocardial oxygen delivery in patients with coronary artery spasm and is responsible for the effectiveness of verapamil hydrochloride in vasospastic (Prinzmetal's or variant) as well as unstable angina at rest. (nih.gov)
  • Atrial fibrillation in the setting of aortic stenosis is considered a medical emergency, and sinus rhythm should be restored urgently in patients who are hemodynamically unstable. (medscape.com)
  • 1. Atrial fibrillation may impair coronary blood flow by tachycardia and reflex vasoconstriction. (portlandpress.com)
  • Aortic stenosis (AS) is the obstruction of blood flow across the aortic valve. (medscape.com)
  • Doppler interrogation of the aortic valve makes use of the modified Bernoulli equation (gradient = 4 × velocity 2 ) to assess the severity of the stenosis. (medscape.com)
  • The only definitive treatment for aortic stenosis in adults is aortic valve replacement, performed surgically or percutaneously. (medscape.com)
  • Regardless of the etiology, calcification of the aortic valve leads to stenosis, inevitably resulting in a fixed obstruction to LV emptying. (medscape.com)
  • Myocardial Fibrosis Predicts 10-Year Survival in Patients Undergoing Aortic Valve Replacement. (onteenstoday.com)
  • Aortic valve stenosis and regurgitation 21. (muni.cz)
  • Transcatheter Aortic Valve Replacement (TAVR) is used for patients with aortic stenosis, who are very weak and cannot tolerate a major heart surgery. (yashodahospitals.com)
  • Aortic valve stenosis is a condition wherein the valve is not able to open and close completely. (yashodahospitals.com)
  • METHODS: A total of 123 patients scheduled for coronary angiography underwent intermediate (mechanical index 0.5) triggered replenishment MCE and SPECT imaging at rest and after vasodilator stress. (northwestern.edu)
  • Transient ischemic dilation (TID) on stress SPECT myocardial perfusion imaging (MPI) is defined as the apparent presence of left ventricular (LV) dilation on poststress relative to rest images. (snmjournals.org)
  • The combination of CTA and CTP had similar diagnostic power to the combination of ICA and SPECT myocardial perfusion imaging (MPI) in identifying revascularized patients at 30 days (p = 0.13). (acc.org)
  • Schwartz says his center has reported good- to excellent-quality images in patients who are obese or superobese (body mass index of 30 to 64) with CZT SPECT, which has set the stage for diagnostic evaluation compared with coronary angiography in this underserved and growing population. (radiologytoday.net)
  • Further, T2* mapping, another parametric imaging approach, can detect and quantify myocardial iron deposition, primarily to assess iron overload cardiomyopathy. (medscape.com)
  • CT coronary angiography can detect coronary plaque with high resolution, estimate the degree of functional stenosis and characterise plaque features. (bmj.com)
  • Endocardial and epicardial blood flows were measured by the radioactive microsphere technique prior to the application of the stenosis and after one hour and 2 hours of fibrillation. (johnshopkins.edu)
  • Endocardial and epicardial flow in the distribution of the unstenosed circumflex coronary artery remained unchanged. (johnshopkins.edu)
  • Strain rate imaging is superior to two-dimensional DSE and tissue Doppler imaging for the assessment of myocardial viability. (nih.gov)
  • The emerging field of coronary physiology allows operators to perform quantitative measurements of lesion severity and are evidence based to guide the need for coronary intervention. (rcpe.ac.uk)
  • The effect of a critical coronary artery stenosis on myocardial blood flow and metabolism in the fibrillating heart was assessed by placing 10 dogs on cardiopulmonary bypass, venting the ventricle, inducing ventricular fibrillation, and applying critical stenosis to the left anterior descending coronary artery (LAD). (johnshopkins.edu)
  • Contrast-enhanced T1 mapping is mostly used for calculating extracellular volume fraction (ECV) - that is, the ratio of pre- and postcontrast myocardial T1 to that of the ventricular blood compartment T1. (medscape.com)
  • Selective arterial-coronary venous lactate differences were determined at control, one hour, and 2 hours. (johnshopkins.edu)
  • Verapamil hydrochloride is a calcium ion influx inhibitor (slow-channel blocker or calcium ion antagonist) that exerts its pharmacologic effects by modulating the influx of ionic calcium across the cell membrane of the arterial smooth muscle as well as in conductile and contractile myocardial cells. (nih.gov)
  • Also the results of bypass surgery were improved by the use of arterial grafts [ 7 ] and percutaneous coronary interventions (PCI) have been made more effective through the introduction of stents, particularly drug-eluting stents. (medscape.com)
  • This unloading of the heart reduces myocardial energy consumption and oxygen requirements and probably accounts for the effectiveness of verapamil hydrochloride in chronic stable effort angina. (nih.gov)
  • This study assesses the relationship between the distribution of thallium-201 and myocardial blood flow during coronary vasodilation induced by intravenous dipyridamole in canine models of partial and complete coronary artery stenosis. (jci.org)
  • Overall, this leads to relaxation of the smooth muscle and coronary vasodilation. (wikipedia.org)
  • Adenosine causes nonselective activation of four different receptors, including A2A-mediated vasodilation of the coronary microcirculation and 'off target' A2B receptor-mediated mast cell degranulation and bronchial constriction. (rcpe.ac.uk)
  • On the other hand, outlet resistance (i.e., microvascular resistance), stenosis degree, and percent stenosis length contributed the most to FFR computation and needed to be tuned to the patient of interest. (duke.edu)
  • This multicenter, multinational, prospective study included 381 patients with suspected CAD who had been referred for clinically indicated coronary angiography. (acc.org)
  • CCTA is appropriate in symptomatic patients with intra-coronary stent diameters great than or equal to 3.0 mm, implementing measures to improve stent imaging accuracy, such as heart-rate control, iterative, sharp kernel, and mono-energetic reconstruction. (diagnosticimaging.com)
  • CCT imaging for CAD initially quantified coronary artery calcification, as it was readily detected on CT images, and quantified to generate a coronary artery calcium score (CACS) that represented a surrogate marker of the presence and extent of CAD. (bmj.com)
  • [ 1 ] Symptoms of aortic stenosis usually develop gradually after an asymptomatic latent period of 10-20 years. (medscape.com)
  • The development of symptoms due to aortic stenosis provides a clear indication for replacement. (medscape.com)
  • Many cases of pulmonic stenosis are mild and do not cause symptoms. (adam.com)