Bone Marrow NeoplasmsMyeloproliferative DisordersJanus Kinase 2Bone MarrowBone and BonesPrimary MyelofibrosisPolycythemia VeraThrombocythemia, EssentialBone Marrow CellsMyelodysplastic-Myeloproliferative DiseasesBone Marrow TransplantationReceptors, ThrombopoietinBone RemodelingThrombocytosisLeukemia, Myelomonocytic, ChronicBone DensityLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeBone Marrow DiseasesBone RegenerationHematopoietic Stem CellsLeukemia, Myelomonocytic, JuvenileBone ResorptionMyelodysplastic SyndromesAnemia, RefractoryMutationBone NeoplasmsBone Marrow ExaminationSplenomegalyOsteogenesisBone DevelopmentProto-Oncogene Proteins c-cblBone SubstitutesHematologic NeoplasmsPhiladelphia ChromosomeBone DiseasesLeukemia, Myeloid, AcuteLeukemia, Myelogenous, Chronic, BCR-ABL PositiveBone MatrixJanus KinasesOsteoblastsTissue EngineeringMegakaryocyte Progenitor CellsMice, Inbred C57BLSTAT5 Transcription FactorTissue ScaffoldsNeoplasmsLeukemiaMegakaryocytesCell DifferentiationHematopoiesisLeukemia, MyeloidHematologyBone TransplantationCell ProliferationMyeloid Progenitor CellsMyelopoiesisClonal EvolutionBlast CrisisFusion Proteins, bcr-ablBone Marrow PurgingAnemia, SideroblasticFemurBone Morphogenetic Protein 2Cells, CulturedCalcification, PhysiologicGene Knock-In TechniquesPancreatic NeoplasmsProtein Kinase InhibitorsMutation, MissenseColony-Forming Units AssayDNA Mutational AnalysisAmino Acid SubstitutionMegakaryocyte-Erythroid Progenitor CellsHematopoiesis, ExtramedullaryTransplantation, HomologousCell Transformation, NeoplasticBone Diseases, MetabolicFractures, BoneCalcium PhosphatesGranulocytesTibiaMice, TransgenicOsteoclastsPrognosisDisease Models, AnimalAlkaline PhosphataseHaversian SystemPhenotypeMesenchymal Stromal CellsProto-Oncogene ProteinsBiocompatible MaterialsFlow CytometryNeoplasms, Cystic, Mucinous, and SerousSignal TransductionDisease ProgressionOsteocytesBone Morphogenetic ProteinsX-Ray MicrotomographyPoint MutationDurapatite