In one such example, HTS was used to measure the patient-specific TCR sequences in patients with cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome) after a non-myeloablative allogeneic transplant. (stanford.edu)
This phase I trial identifies the best dose, possible benefits, and/or side effects of duvelisib in combination with nivolumab in treating patients with stage IIB-IVB mycosis fungoides and Sezary syndrome. (clfoundation.org)
Giving duvelisib in combination with nivolumab may work better than giving each of these drugs individually, or treating with the usual approach in patients with mycosis fungoides and Sezary syndrome. (clfoundation.org)
While skin cancer can manifest in various forms, this comprehensive guide will focus on four major types: Basal Cell Carcinoma, Cutaneous T-Cell Lymphoma, Mycosis Fungoides, and Sezary Syndrome. (senderrarx.com)
Mycosis fungoides and Sezary syndrome: an update // Curr Oncol Rep. - 2006. (pdt-journal.com)
Results from a multi-center phase III trial examiniing the safety and efficacy of two doses of denileukin diftitox (Ontak) in patients with biopsy-confirmed CD25 assay-positive cutaneous T-cell lymphoma (CTCL), including both mycosis fungoides and Sezary Syndrome suggest merely that this recombinant protein can outperform a placebo. (lymphomainfo.net)
Cutaneous19
Sézary disease, or Sézary syndrome, is a type of cutaneous T-cell lymphoma that was first described by Albert Sézary. (wikipedia.org)
Mycosis fungoides is the most common form of a type of blood cancer called cutaneous T-cell lymphoma. (medlineplus.gov)
As the nomenclature and description of the disease spectrum under the descriptive term parapsoriasis evolved, the primary focus has been on the distinction of whether the disorder progresses to mycosis fungoides (MF) or cutaneous T-cell lymphoma (CTCL). (medscape.com)
One of the most common blood-related cancers is mycosis fungoides, a type of cutaneous T-cell lymphoma. (trebalm.com)
Cutaneous T-cell lymphoma is a general term from mycosis fungoides or occur spontane- to identify non-Hodgkin's T-cell lymphomas ously, although some authors now consider that primarily affect the skin. (bvsalud.org)
subtypes of cutaneous T-cell lymphoma, SS is a malignant neoplasm originating the most common of which are mycosis from T lymphocytes, which involves the fungoides and Sézary syndrome (SS). (bvsalud.org)
Mycosis fungoides and Sézary syndrome are the 2 main types of cutaneous T-cell lymphomas. (msdmanuals.com)
Mycosis fungoides (cutaneous T-cell lymphoma) can be difficult to distinguish from nonmalignant chronic dermatoses. (msdmanuals.com)
Mycosis fungoides (MF) is the most common form of primary cutaneous lymphoma, resulting from the infiltration of malignant T cells into skin tissues. (iranjd.ir)
The commonest and least serious of the deep mycoses, characterized by nodular lesions of the cutaneous and subcutaneous tissues. (lookformedical.com)
en] There are many radiosensitive diseases associated to the skin such as mycosis fungoids and the syndrome of Sezary that are part of a sub-group of cutaneous diseases type T-cell lymphoma. (iaea.org)
Increased expression of CTLA-4 in malignant T-cells from patients with mycosis fungoides -- cutaneous T cell lymphoma. (uams.edu)
Immune function abnormalities in peripheral blood mononuclear cell cytokine expression differentiates stages of cutaneous T-cell lymphoma/mycosis fungoides. (uams.edu)
Revisions to the staging and classification of mycosis fungoides and Sézary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous task force of the European Organization for Research and Treatment of Cancer (EORTC) // Blood. (pdt-journal.com)
Mycosis fungoides (MF) and its variants represent the most common form of cutaneous T-cell lymphomas. (appliedradiationoncology.com)
Lymphoma2
Mycosis fungoides -This is the most common type of skin lymphoma, accounting for about half of all cases. (uhapo.co.in)
However, this description includes several skin diseases that likely arise from a variable degree of lymphocytic inflammation, which may have nonspecific histopathology to histology, with abnormal lymphocytes seen in mycosis fungoides. (medscape.com)
CTCL1
Mycosis Fungoides is the most common subtype of CTCL and typically progresses slowly over many years. (senderrarx.com)
The immunohistochemical features are very similar to those presented in mycosis fungoides except for the following differences: More monotonous cellular infiltrates (large, clustered atypical pagetoid cells) in Sézary syndrome Sometimes absent epidermotropism Increased lymph node involvement with infiltrates of Sézary syndrome. (wikipedia.org)
Mycosis fungoides and Sézary syndrome are uncommon chronic T-cell non-Hodgkin lymphomas primarily affecting the skin and occasionally the lymph nodes. (msdmanuals.com)
PURPOSE: This phase II trial is studying how well lenalidomide works in treating patients with relapsed mycosis fungoides/Sezary syndrome. (stanford.edu)
EORTC consensus recommendations for the treatment of mycosis fungoides/Sezary syndrome // Eur J Cancer. (pdt-journal.com)
Leukemic1
In some cases, a leukemic phase called Sézary syndrome is characterized by the appearance of malignant T cells with serpentine nuclei in the peripheral blood. (msdmanuals.com)
The question ought to be what are myelodysplastic syndromes (MDS), since this is a group of similar blood and bone marrow diseases that. (lymphomainfo.net)
Regarding the epidemiological distribu- skin biopsy of the dorsal and anterior chest tion of this syndrome, it predominates in region. (bvsalud.org)
In Sézary syndrome, the skin is typically diffusely red with cracking of the palms and soles. (msdmanuals.com)
Genes2
Certain variations of HLA genes may affect the risk of developing mycosis fungoides or may impact progression of the disorder. (medlineplus.gov)
Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome. (cdc.gov)
Chromosome Abnormalities1
It is unclear whether these genetic changes play a role in mycosis fungoides, although the tendency to acquire chromosome abnormalities (chromosomal instability) is a feature of many cancers. (medlineplus.gov)
Diagnosis1
A bone marrow smear was performed, in which 'cerebriform' cells were identified, confirming the diagnosis of Sézary syndrome. (bvsalud.org)
Stages1
Mycosis fungoides may progress slowly through several stages, although not all people with the condition progress through all stages. (medlineplus.gov)
Plaques1
The tumors in mycosis fungoides, which are composed of cancerous T cells, are raised nodules that are thicker and deeper than plaques. (medlineplus.gov)
Tumors1
Mycosis fungoides was so named because the tumors can resemble mushrooms, a type of fungus. (medlineplus.gov)
Infiltrates1
Folliculotropic mycosis fungoides is a distinct variant of mycosis fungoides characterized by the presence of folliculotropic infiltrates with preferential involvement of the head and neck region. (nextstepsinderm.com)
The only difference between pagetoid reticulosis and mycosis fungoides is seen on biopsy. (vin.com)
Disorder1
El-Darouti et al reported on a 7-year study of a hypopigmented disorder that the researchers believe should be classified as a new variant of parapsoriasis en plaque. (medscape.com)
This complication almost never happens in dogs but happens in approximately 5 percent of humans with mycosis fungoides, so the term may come up if you do any internet research. (vin.com)
Disease2
Immunogenetic factors in mycosis fungoides: can the HLA system influence the susceptibility and prognosis of the disease? (cdc.gov)
Mycosis fungoides: association of KIR ligands and HLA-DQB1*05 with bad prognosis of the disease. (cdc.gov)
Progress1
Mycosis fungoides can progress to what is called Sézary syndrome. (vin.com)
Development1
It is possible that other factors, such as environmental exposure or certain bacterial or viral infections, are involved in the development of mycosis fungoides. (medlineplus.gov)
Cases1
In the Western population, there are around 3 cases of Sézary syndrome per 1,000,000 people. (wikipedia.org)